Derangements of liver tissue bioenergetics in concanavalin A-induced hepatitis.

abstract：BACKGROUND:Acetaminophen (APAP) overdose induces massive hepatocyte necrosis. Liver regeneration is a vital process for survival after a toxic insult. Since hepatocytes are mostly in a quiescent state (G0), the regeneration process requires the priming of hepatocytes by cytokines such as TNF-α and IL-6. Ringer's lactat...

journal_title：BMC gastroenterology

authors： Yang R,Zhang S,Kajander H,Zhu S,Koskinen ML,Tenhunen J

更新日期：2011-11-15 00:00:00

abstract：BACKGROUND:Alpha-fetoprotein (AFP)-producing pancreatic neuroendocrine tumors (pNETs) are rare, and the few reported cases usually coexisted with other malignant components such as adenocarcinoma or hepatoid carcinoma. We present here the first case of pure AFP-producing pNET. CASE PRESENTATION:A 56-year-old male pati...

journal_title：BMC gastroenterology

authors： Zhu X,Yong H,Zhang L,Huang Y,Zheng J,Liu C,Xiu D,Zhang P

更新日期：2015-02-12 00:00:00

abstract：BACKGROUND:The use of thickeners is a standard therapy for decreasing episodes of regurgitation or vomiting in infants. However, it remains to be investigated whether thickener is effective for vomiting and/or chronic respiratory symptoms in children with cerebral palsy. METHODS:We enrolled 18 neurologically impaired ...

journal_title：BMC gastroenterology

authors： Miyazawa R,Tomomasa T,Kaneko H,Arakawa H,Shimizu N,Morikawa A

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:Endothelial nitric oxide synthase (eNOS) has previously been detected in the glandular part of the human gastric mucosa. Furthermore, nitric oxide (NO) has been shown to influence gastric secretion in various animal models. The present study was conducted to investigate the influence of exogenously and endog...

journal_title：BMC gastroenterology

authors： Berg A,Redeen S,Ericson AC,Sjöstrand SE

更新日期：2004-08-06 00:00:00

abstract：BACKGROUND:The combination of boceprevir or telaprevir with peginterferon-alfa and ribavirin for the treatment of patients infected with HCV genotype 1 has led to significantly increased rates of sustained virological response (SVR) in phase III trials. There is only limited data regarding the safety and efficacy in a ...

journal_title：BMC gastroenterology

authors： Wehmeyer MH,Eißing F,Jordan S,Röder C,Hennigs A,Degen O,Hüfner A,Hertling S,Schmiedel S,Sterneck M,van Lunzen J,Lohse AW,Schulze zur Wiesch J,Lüth S

更新日期：2014-05-05 00:00:00

abstract：BACKGROUND:Gastric ulcers are a frequent problem in the United States. Proton pump inhibitors have been shown to increase healing rates and improve clinical symptoms. The objective of this study is to compare gastric ulcer healing rates for patients treated with a proton pump inhibitor (PPI) (omeprazole, rabeprazole, p...

journal_title：BMC gastroenterology

authors： Salas M,Ward A,Caro J

更新日期：2002-07-15 00:00:00

abstract：BACKGROUND:To investigate the effect of albumin infusion on cirrhotic patients admitted for acute gastrointestinal bleeding. METHODS:Medical records of cirrhotic patients who admitted due to acute gastrointestinal bleeding through January 2009 to December 2018 were reviewed. Clinical data and the total amount of album...

journal_title：BMC gastroenterology

authors： Wang Z,Xie YW,Lu Q,Yan HL,Liu XB,Long Y,Zhang X,Yang JL

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:It is unknown whether narrow-band imaging (NBI) could be more effective than high-definition white-light endoscopy (HD-WLE) in detecting serrated lesions in patients with prior serrated lesions > 5 mm not completely fulfilling serrated polyposis syndrome (SPS) criteria. METHODS:We conducted a randomized, cr...

journal_title：BMC gastroenterology

authors： Riu Pons F,Andreu M,Naranjo D,Álvarez-González MA,Seoane A,Dedeu JM,Barranco L,Bessa X

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:High dose intravenous proton pump inhibitor after endoscopic therapy for peptic ulcer bleeding has been recommended as adjuvant therapy. Whether oral proton pump inhibitor can replace intravenous proton pump inhibitor in this setting is unknown. This study aims to compare the clinical efficacy of oral and in...

journal_title：BMC gastroenterology

authors： Yen HH,Yang CW,Su WW,Soon MS,Wu SS,Lin HJ

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:Inadequate response to proton pump inhibitor (PPI) therapy in patients with gastroesophageal reflux disease (GERD) is reported in up to 40%. Patients with non erosive reflux disease (NERD) have lower response rates compared to patients with erosive reflux disease (ERD); pH metry contributes to GERD diagnosis...

journal_title：BMC gastroenterology

authors： Kandulski A,Peitz U,Mönkemüller K,Neumann H,Weigt J,Malfertheiner P

更新日期：2013-01-16 00:00:00

abstract：BACKGROUND:Pancreatic hamartoma is an extremely rare benign disease of the pancreas. Only 30 cases have been reported to date. CASE PRESENTATION:A 68-year-old man presented with an asymptomatic solid and multi-cystic lesion in the uncus of the pancreas, incidentally detected on abdominal enhanced computed tomography. ...

journal_title：BMC gastroenterology

authors： Matsushita D,Kurahara H,Mataki Y,Maemura K,Higashi M,Iino S,Sakoda M,Shinchi H,Ueno S,Natsugoe S

更新日期：2016-01-14 00:00:00

abstract：BACKGROUND:Gastric tuberculosis mimicking submucosal tumors is extremely rare and often misdiagnosed. CASE PRESENTATION:Three cases of gastric tuberculosis mimicking submucosal tumors were identified among patients admitted to local county hospitals because of upper abdominal discomfort and pain, with gastroscopy show...

journal_title：BMC gastroenterology

authors： Zhu R,Zhou Y,Wang H,Di L,Zhao K,Tuo B,Wu H

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:Perianal fistula surgery can damage the anal sphincters which may cause faecal incontinence. By measuring regional pressures, 3D-HRAM potentially provides better guidance for surgical strategy in patients with perianal fistulas. The aim was to measure regional anal pressures with 3D-HRAM and to compare these...

journal_title：BMC gastroenterology

authors： Felt-Bersma RJF,Vlietstra MS,Vollebregt PF,Han-Geurts IJM,Rempe-Sorm V,Vander Mijnsbrugge GJH,Molenaar CBH

更新日期：2018-04-04 00:00:00

abstract：BACKGROUND:Signet ring cell carcinoma of the colon and rectum is rare, and most cases are detected at an advanced stage. We present a case of primary signet ring cell carcinoma detected at an early stage by magnifying endoscopy with narrow-band imaging (NBI) and crystal violet staining. CASE PRESENTATION:A 73-year-old...

journal_title：BMC gastroenterology

authors： Ohnita K,Isomoto H,Akashi T,Hashiguchi K,Matsushima K,Minami H,Akazawa Y,Yamaguchi N,Takeshima F,To K,Takeshita H,Yasui H,Abe K,Nakao K

更新日期：2015-07-24 00:00:00

abstract：BACKGROUND:Polyethylene glycol is commonly used to manage constipation and is available with or without electrolytes. The addition of electrolytes dates back to its initial development as lavage solutions in preparation for gastrointestinal interventions. The clinical utility of the addition of electrolytes to polyethy...

journal_title：BMC gastroenterology

authors： Katelaris P,Naganathan V,Liu K,Krassas G,Gullotta J

更新日期：2016-03-31 00:00:00

abstract：BACKGROUND:Rebamipide is a gastroprotective agent with promising results against gastric damage induced by non-steroidal anti-inflammatory drugs. The present study evaluated if rebamipide protects against naproxen-induced gastric damage in healthy volunteers. Changes in gastric PGE2 tissue concentration were also evalu...

journal_title：BMC gastroenterology

authors： Gagliano-Jucá T,Moreno RA,Zaminelli T,Napolitano M,Magalhães AF,Carvalhaes A,Trevisan MS,Wallace JL,De Nucci G

更新日期：2016-06-04 00:00:00

abstract：BACKGROUND:The evidence on the role of gut microbiota in post-infectious irritable bowel syndrome (PI-IBS) is convincing. Lactobacillus spp. positively affect IBS symptoms, although the mechanisms through which probiotics exert their beneficial effects are largely unknown. The aim of the study is to evaluate the role o...

journal_title：BMC gastroenterology

authors： Compare D,Rocco A,Coccoli P,Angrisani D,Sgamato C,Iovine B,Salvatore U,Nardone G

更新日期：2017-04-14 00:00:00

abstract：BACKGROUND:Liver injury and regeneration involve complicated processes and are affected by various physio-pathological conditions. Surgically, severe liver injury after surgical resection often leads to fatal liver failure, especially with some underlying pathological conditions such as steatosis. Therefore, protection...

journal_title：BMC gastroenterology

authors： Haga S,Yimin,Ozaki M

更新日期：2017-01-13 00:00:00

abstract：BACKGROUND:Current literature has demonstrated that host glutamine depletion facilitates tumorigenesis. Likewise, the glutamine transporter SLC38A1 is putatively associated with malignant transformation and tumor progression. Taken together, this forms the premise for undertaking the current study. The twofold aim of t...

journal_title：BMC gastroenterology

authors： Xie J,Li P,Gao HF,Qian JX,Yuan LY,Wang JJ

更新日期：2014-04-09 00:00:00

abstract：BACKGROUND:From the morphological appearance, it was impossible to distinguish terminal portal venules from small lymphatic vessels in the portal tract even using histochemical microscopic techniques. Recently, D2-40 was found to be expressed at a high level in lymphatic endothelial cells (LECs). This study was underta...

journal_title：BMC gastroenterology

authors： Yokomori H,Oda M,Kaneko F,Kawachi S,Tanabe M,Yoshimura K,Kitagawa Y,Hibi T

更新日期：2010-11-08 00:00:00

abstract：BACKGROUND:Little data exists on the factors associated with health care seeking behaviour for primary symptoms of colorectal cancer (CRC). This study aimed to identify individual, provider and psychosocial factors associated with (i) ever seeking medical advice and (ii) seeking early medical advice for primary symptom...

journal_title：BMC gastroenterology

authors： Courtney RJ,Paul CL,Sanson-Fisher RW,Macrae FA,Attia J,McEvoy M

更新日期：2012-08-03 00:00:00

abstract：BACKGROUND:CMUSE is a rare disease whose diagnosis remains difficult because the lesion is confined to the small bowel. CASE PRESENTATION:Here, we present a case of 43-year-old female patient suffered chronic abdominal pain for 20 years, and finally diagnosed with CMUSE. Capsule endoscopy was performed when general en...

journal_title：BMC gastroenterology

authors： Tao EW,Zou TH,Wang YF,Tang JT,Chen YX,Gao QY

更新日期：2019-04-03 00:00:00

abstract：BACKGROUND:Apoptosis inhibitor of macrophage (AIM) and adipocytokines are involved in the metabolic syndrome, which has been putatively associated with the progression of chronic hepatitis C (CHC). However, the association between these cytokines and CHC is not fully elucidated. The aim of this study is to test whether...

journal_title：BMC gastroenterology

authors： Mera K,Uto H,Mawatari S,Ido A,Yoshimine Y,Nosaki T,Oda K,Tabu K,Kumagai K,Tamai T,Moriuchi A,Oketani M,Shimada Y,Hidaka M,Eguchi S,Tsubouchi H

更新日期：2014-02-13 00:00:00

abstract：BACKGROUND:The natural course and treatment strategies for asymptomatic or oligosymptomatic pancreatic necrosis are still poorly defined. The aim of this retrospective study was to establish criteria for the need of intervention in patients with pancreatic necrosis. METHODS:A total of 31 consecutive patients (18 male,...

journal_title：BMC gastroenterology

authors： Jürgensen C,Arlt A,Neser F,Fritscher-Ravens A,Stölzel U,Hampe J

更新日期：2012-05-14 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of liver diseases, ranging from pure steatosis to nonalcoholic steatohepatitis (NASH), and eventually to liver cirrhosis with its complications. Identifying advanced fibrosis in patients is crucial to evaluating prognosis and possible therapeu...

journal_title：BMC gastroenterology

authors： Raszeja-Wyszomirska J,Szymanik B,Ławniczak M,Kajor M,Chwist A,Milkiewicz P,Hartleb M

更新日期：2010-06-28 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is defined as a multifactorial disorder associated with visceral hypersensitivity, altered gut motility and dysfunction of the brain-gut axis. Gut microbiota and its metabolites are proposed as possible etiological factors of IBS. Short chain fatty acids (SCFAs) induce both inh...

journal_title：BMC gastroenterology

authors： Shaidullov IF,Sorokina DM,Sitdikov FG,Hermann A,Abdulkhakov SR,Sitdikova GF

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:To exam the biochemical, obstetric management and pregnancy outcome in women with intrahepatic cholestasis of pregnancy (ICP) and treatment with ursodeoxycholic acid (UDCA). METHODS:Pregnancy outcome in patients with ICP (N = 307) was studied and patients treated with UDCA (N = 208) vs. no UDCA were compare...

journal_title：BMC gastroenterology

authors： Joutsiniemi T,Timonen S,Linden M,Suvitie P,Ekblad U

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Studies have demonstrated usefulness of cognitive-behavioural therapy (CBT) in managing distress in inflammatory bowel disease (IBD); however, few have focused on IBD course. The present trial aimed to investigate whether adding CBT to standard treatment prolongs remission in IBD in comparison to standard th...

journal_title：BMC gastroenterology

authors： Mikocka-Walus A,Bampton P,Hetzel D,Hughes P,Esterman A,Andrews JM

更新日期：2015-05-02 00:00:00

abstract：BACKGROUND:It is believed that inflammatory bowel diseases (IBD) result from an imbalance in the intestinal immune response towards the luminal microbiome. Dectin-1 is a widely expressed pattern recognition receptor that recognizes fungi and upon recognition it mediates cytokine responses and skewing of the adaptive im...

journal_title：BMC gastroenterology

authors： Heinsbroek SE,Oei A,Roelofs JJ,Dhawan S,te Velde A,Gordon S,de Jonge WJ

更新日期：2012-04-16 00:00:00

abstract：BACKGROUND:In China, the incidence of Inflammatory bowel disease (IBD) has shown a significant growth trend. Analysis of the epidemiology, clinical manifestations, diagnostic means, and treatment of IBD will further improve the clinician's understanding of IBD, improve knowledge and further enable early diagnosis and s...

journal_title：BMC gastroenterology

authors： Zhai H,Liu A,Huang W,Liu X,Feng S,Wu J,Yao Y,Wang C,Li Q,Hao Q,Hu J,Zhang S

更新日期：2016-01-12 00:00:00