Chronic treatment with a long-acting somatostatin analogue in a patient with intestinal carcinoid tumor: occurrence of cholelithiasis.

Abstract:

:The long-acting somatostatin analogue SMS 201-995 has been used efficaciously in the therapy of metastatic carcinoid tumor, vasoactive intestinal peptide producing islet cell carcinoma, acromegaly, and TSH secreting pituitary tumors. We report the development of a gallstone in a patient treated for 23 months with a long acting somatostatin analogue for a metastatic carcinoid tumor. Symptomatic improvement and a reduction in the urinary excretion of 5-hydroxyindoleacetic acid occurred. There was no evidence of a gallstone on ultrasound and CT scan of the abdomen prior to somatostatin therapy. A progressively enlarging, asymptomatic gallstone developed during therapy.

journal_name

J Endocrinol Invest

authors

Roti E,Minelli R,Gardini E,Salvi M,Bianconi L,Balducci L,Manfredi A,Braverman LE

doi

10.1007/BF03348589

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

69-72

issue

1

eissn

0391-4097

issn

1720-8386

journal_volume

13

pub_type

杂志文章
  • Hyperprolactinemia affects spermiogenesis in adult male rats.

    abstract::The mechanisms underlying the antifertility effects of hyperprolactinemia have yet to be established in an appropriate experimental model. Hyperprolactinemia is a known side effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be dopamine type-D2 receptor antagonist. In our earlier study in adu...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345528

    authors: Aleem M,Choudhari J,Padwal V,Balasinor N,Parte P,Gill-Sharma MK

    更新日期:2005-01-01 00:00:00

  • Proteomic analysis of human thyroid fine needle aspiration fluid.

    abstract::The aim of this study was to determine the protein pattern of human thyroid fine needle aspiration fluid (FNA) using a proteomic approach. FNA proteins were separated using 2-dimensional gel electrophoresis (2DE), digested and then analyzed by peptide mass fingerprinting. For the first time, we provided an image of th...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349229

    authors: Giusti L,Iacconi P,Ciregia F,Giannaccini G,Basolo F,Donatini G,Miccoli P,Lucacchini A

    更新日期:2007-11-01 00:00:00

  • Corticosterone methyloxydase deficiency type II in a Croatian girl.

    abstract::This is a brief case report on a four-month-old girl who was admitted for failure to thrive and moderate dehydration. On admission she was mildly dehydrated and undernourished but with otherwise normal physical findings. Laboratory investigation disclosed mild but constant hyponatremia and hyperkalemia, very high plas...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348705

    authors: Mardesić D,Sarnavka V,Dumić M,Stipić V

    更新日期:1992-03-01 00:00:00

  • Endothelin-1 and endothelin-3 stimulate insulin release by isolated rat pancreatic islets.

    abstract::Endothelins (ETs) are potent vasoconstrictive peptides released from the endothelium and other tissues, which act on target cells by receptorial calcium-mediated mechanisms. ET-1 levels are increased in diabetes, and observations suggest the involvement of ETs in the pathogenesis of diabetic angiopathy. However, it is...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343715

    authors: De Carlo E,Milanesi A,Martini C,Maffei P,Sicolo N,Scandellari C

    更新日期:2000-04-01 00:00:00

  • Immunohistochemical detection of estrogen and progesterone receptors in the normal urinary bladder and in pseudomembranous trigonitis.

    abstract::According to recent studies showing the presence of estrogens receptors (ERs) in the human female lower urinary tract, we performed ER and progesterone receptor (PR) assays in fresh frozen and paraffin embedded biopsies taken from the urinary bladder. Fourteen females undergoing endoscopy during staging for gynecologi...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347639

    authors: Pacchioni D,Revelli A,Casetta G,Cassoni P,Piana P,Tizzani A,Bussolati G,Massobrio M

    更新日期:1992-11-01 00:00:00

  • Presence of cortistatin in the human pancreas.

    abstract::Cortistatin (CST), a 17-amino acid peptide partially homologous to somatostatin (SRIF), has been originally isolated from the cerebral cortex and recently found in monocytes and macrophages of the immune system. CST binds all 5 SRIF receptors, as well the GH secretagogue (GHS)/ghrelin receptors. CST exerts sleep promo...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347348

    authors: Papotti M,Tarabra E,Allia E,Bozzalla-Cassione F,Broglio F,Deghenghi R,Ghigo E,Muccioli G

    更新日期:2003-08-01 00:00:00

  • Hyperthyroidism due to familial pituitary resistance to thyroid hormone: successful control with 3, 5, 3' triiodothyroacetic associated to propranolol.

    abstract::We herein describe a family with thyroid hormone resistance. Thyroid hormones and basal TSH were elevated. Pituitary tumor or abnormality in thyroid hormone binding proteins were ruled out by appropriate tests. Mother and sister of the propositus presented similar abnormal hormonal features but no hyperthyroidism. Ini...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347890

    authors: Aguilar Diosdado M,Escobar-Jimenez L,Fernandez Soto ML,Garcia Curiel A,Escobar-Jimenez F

    更新日期:1991-09-01 00:00:00

  • Growth hormone insufficiency in a girl with the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

    abstract::Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is an inherited disease which may comprise many endocrine and non-endocrine components. GH insufficiency has not been recognised as a classical manifestation of this syndrome. We describe the case of a girl with APECED, who presented with four end...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345481

    authors: Franzese A,Valerio G,Di Maio S,Iannucci MP,Bloise A,Tenore A

    更新日期:1999-01-01 00:00:00

  • A rapid procedure for the quantitation of natriuretic peptide RNAs by competitive RT-PCR in congenital heart defects.

    abstract::We report an original application of quantitative reverse transcription-polymerase chain reaction (Q.RT-PCR) for the evaluation of atrial natriuretic factor (ANF), brain natriuretic peptide (BNP) and beta-actin mRNA in small atrial samples (10-15 mg). A fixed amount of total RNA was simultaneously reverse transcribed ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343655

    authors: Iascone MR,Vittorini S,Collavoli A,Cupelli A,Kraft G,Biagini A,Clerico A

    更新日期:1999-12-01 00:00:00

  • Multiple endocrine neoplasia type 2A/localized cutaneous lichen amyloidosis associated with malignant pheochromocytoma and ganglioneuroma.

    abstract::We hereby present a rare variant of multiple endocrine neoplasia type 2A (MEN2A) associated with a rare skin disease primary cutaneous lichen amyloidosis and discrete malignant pheochromocytoma in both adrenal glands and pancreatic tail, and interestingly accompanied ganglioneuroma located in retroperitoneum in a 34-y...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347557

    authors: Gullu S,Gursoy A,Erdogan MF,Dizbaysak S,Erdogan G,Kamel N

    更新日期:2005-09-01 00:00:00

  • Hyperinsulinemic hypoglycemia associated with ectopic Cushing's syndrome due to a pancreatic endocrine tumor in a Type 2 diabetes mellitus patient: clinical implications of a rare association.

    abstract:BACKGROUND:The coexistence of insulin and ACTH hypersecretion in the same patient is extremely rare. A diabetic patient with a pancreatic endocrine tumor (PET) co-secreting insulin and ACTH is even rarer and has never been described. The combination of these two endocrine syndromes results in a peculiar clinical pictur...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347062

    authors: Filippella M,Davì MV,Doveri G,Lillaz E,Ciccarelli A,Massimetti E,Toaiari M,Falconi M,Colao A,Faggiano A

    更新日期:2011-03-01 00:00:00

  • Characterization of novel genes in AZF regions.

    abstract::The long arm of the Y chromosome contains genes mapped in loci involved in male infertility, short stature and gonadoblastoma. However, many of these genes have not been fully characterized, and are not currently investigated in patients affected by such diseases. We report a study aimed to the genomic characterizatio...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343790

    authors: Stuppia L,Gatta V,Fogh I,Gaspari AR,Grande R,Morizio E,Fantasia D,Pizzuti A,Calabrese G,Palka G

    更新日期:2000-11-01 00:00:00

  • Mineralocorticoid receptor p.I180V polymorphism: association with body mass index and LDL-cholesterol levels.

    abstract:BACKGROUND/AIMS:Aldosterone and the mineralocorticoid receptor (MR) play a major role in sodium balance and blood pressure control. They are also involved in adipocyte metabolism. The aim of this study was to analyze the association between the MR p.I180V polymorphism with hypertension and markers of cardiovascular ris...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346627

    authors: Fernandes-Rosa FL,Bueno AC,de Souza RM,de Castro M,dos Santos JE,Foss MC,Zennaro MC,Bettiol H,Barbieri MA,Antonini SR

    更新日期:2010-07-01 00:00:00

  • Non-specific rheumatic manifestations in patients with Hashimoto's thyroiditis: a pilot cross-sectional study.

    abstract:PURPOSE:Hashimoto's thyroiditis (HT) is often associated with rheumatic disorders (arthritis, etc.), but many HT patients report non-specific rheumatic signs and symptoms in the absence of clinically evident rheumatic diseases. Aim of this study was to evaluate the prevalence of non-specific rheumatic manifestations (R...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-019-01083-w

    authors: Giuffrida G,Bagnato G,Campennì A,Giovinazzo S,Keller KP,Alibrandi A,Roberts WN,Trimarchi F,Ruggeri RM

    更新日期:2020-01-01 00:00:00

  • Synthesis of esters of androgens with unsaturated fatty acids for androgen requiring therapy.

    abstract::Androgens' metabolism and activity are gaining a more and more important role in human physiology particularly referring to aging and to neurodegenerative diseases. Androgen treatment is often required for long-lasting disorders. In order to improve their duration and effects, androgens can be administered as esters o...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/8655

    authors: Aiello F,Garofalo A,Aloisi AM,Lamponi S,Magnani A,Petroni A

    更新日期:2013-06-01 00:00:00

  • The use of ultrasensitive thyroglobulin assays reduces but does not abolish the need for TSH stimulation in patients with differentiated thyroid carcinoma.

    abstract::Measurement of serum Tg using ultrasensitive assays is proposed to replace TSH-stimulated Tg measurement in the follow-up of differentiated thyroid cancer (DTC). Aim of our study was to verify this possibility using two ultrasensitive Tg assays. We selected 215 DTC patients with undetectable (<1 ng/ml) basal serum Tg ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/7571

    authors: Castagna MG,Tala Jury HP,Cipri C,Belardini V,Fioravanti C,Pasqui L,Sestini F,Theodoropoulou A,Pacini F

    更新日期:2011-09-01 00:00:00

  • Heterogeneous phenotype in children affected by non-autoimmune hypothyroidism: an update.

    abstract:BACKGROUND:In the last decades, a higher incidence of congenital hypothyroidism (CH) has been recorded in Italy (1:1940) and worldwide, mainly due to the shift to lower screening TSH cutoffs. Although CH can also be caused by dysgenetic defects, most CH cases have recently been found to be more frequently associated wi...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/s40618-015-0288-5

    authors: Vigone MC,Di Frenna M,Weber G

    更新日期:2015-08-01 00:00:00

  • Associations between two single nucleotide polymorphisms of the adiponectin gene, its circulating concentrations and cardiometabolic risk factors in prepubertal children with and without abdominal obesity.

    abstract:BACKGROUND:The adiponectin gene has been identified as a susceptibility locus for metabolic syndrome, diabetes and cardiovascular disease. AIM:To examine the influence of two single nucleotide polymorphisms (SNPs) of this gene (+276G>T and +45T>G) on circulating adiponectin concentrations, and to evaluate their relati...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.3275/8972

    authors: Galcheva SV,Martorana D,Iotova VM,Yotov Y,Neri TM,Street ME

    更新日期:2013-11-01 00:00:00

  • Subclinical hypothyroidism: the state of the art.

    abstract::Subclinical hypothyroidism (SH) is a common clinical problem, particularly in adulthood and the elderly. Its prevalence is conditioned by several etiological and risk factors. The highest age- and sex-specific rates are in women over 60. SH may be associated with manifestations of mild thyroid failure, which may rever...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03345571

    authors: Arrigo T,Wasniewska M,Crisafulli G,Lombardo F,Messina MF,Rulli I,Salzano G,Valenzise M,Zirilli G,De Luca F

    更新日期:2008-01-01 00:00:00

  • Predictors of electrocardiographic abnormalities in type 1 Diabetes: the Wisconsin Epidemiologic Study of Diabetic Retinopathy.

    abstract:PURPOSE:To determine the incidence and determinants of developing abnormalities on the 12-lead electrocardiogram (ECG) in persons with type 1 diabetes. METHODS:We evaluated the distribution of ECG abnormalities and risk factors for developing new abnormalities in 266 (mean age = 44 years ± 9.0; 50 % female) people wit...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-016-0564-z

    authors: O'Neal WT,Lee KE,Soliman EZ,Klein R,Klein BE

    更新日期:2017-03-01 00:00:00

  • Iodine deficiency in Calabria: characterization of endemic goiter and analysis of different indicators of iodine status region-wide.

    abstract::The distribution of goiter prevalence in schoolchildren (no.=13,984, age 6-14 yr), the neonatal TSH results obtained from the congenital hypothyroidism screening program and the urinary iodine excretion values (no.=284) were employed for the assessment of iodine deficiency in Calabria, a Southern Italy region. Data we...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343991

    authors: Costante G,Grasso L,Schifino E,Marasco MF,Crocetti U,Capula C,Chiarella R,Ludovico O,Nocera M,Parlato G,Filetti S

    更新日期:2002-03-01 00:00:00

  • Prevalence of metabolic syndrome in rural and urban Chinese population in Qingdao.

    abstract:AIMS:To investigate the prevalence of metabolic syndrome and its components in both rural and urban Chinese population. SUBJECTS AND METHODS:A population-based crosssectional survey was conducted in Qingdao, China in 2006 with 6100 Chinese aged 35-74 yr invited and 5355 who attended; 3357 subjects, 1562 urban (46.5%) ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/BF03346711

    authors: Zhao J,Pang ZC,Zhang L,Gao WG,Wang SJ,Ning F,Nan HR,Ren J,Qiao Q,Qingdao 2006 Diabetes Survey Group.

    更新日期:2011-06-01 00:00:00

  • Meal intake similarly reduces circulating concentrations of octanoyl and total ghrelin in humans.

    abstract:UNLABELLED:ABSTRACT. Several data show that meal intake and nutritional status regulate circulating ghrelin concentrations in humans. Ghrelin mainly circulates in two different forms: octanoyl and des-octanoyl ghrelin. Most circulating ghrelin is des-octanoyl ghrelin which is considered inactive because it lacks endocr...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:

    authors: Lucidi P,Murdolo G,Di Loreto C,Parlanti N,De Cicco A,Ranchelli A,Fatone C,Taglioni C,Fanelli C,Santeusanio F,De Feo P

    更新日期:2004-05-01 00:00:00

  • Pituitary imaging abnormalities in patients with and without hypopituitarism after traumatic brain injury.

    abstract::Recent evidence suggests that patients with traumatic brain injury (TBI) are at substantial risk of hypopituitarism. The pathomechanisms, however, are not completely understood yet. Little is known about the association of morphological changes in the sella region with pituitary function in TBI. In this study, we asse...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346291

    authors: Schneider HJ,Sämann PG,Schneider M,Croce CG,Corneli G,Sievers C,Ghigo E,Stalla GK,Aimaretti G

    更新日期:2007-04-01 00:00:00

  • Signals that determine the fate of osteoblastic cells.

    abstract::Signals that determine skeletal cell fate, function and apoptosis are critical to normal bone remodeling. Skeletal cells synthesize growth factors; some regulate cell replication, others regulate osteoblastic differentiation. Bone morphogenetic proteins (BMP) and Wnts induce the differentiation of mesenchymal cells to...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Canalis E,Deregowski V,Pereira RC,Gazzerro E

    更新日期:2005-01-01 00:00:00

  • Incidence of congenital hypothyroidism in the Autonomous Province of Bolzano: benefit of increased iodine intake.

    abstract:PURPOSE:Although a nation-wide salt iodization program on voluntary basis was implemented in 2005, many areas in our country are still characterized by mild iodine deficiency. Differently from the rest of Italy, an efficient program of iodine prophylaxis was implemented in 1981 in the Autonomous Province of Bolzano. Th...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-014-0206-2

    authors: Olivieri A,Radetti G,Medda E,Italian Study Group for Congenital Hypothyroidism.

    更新日期:2015-02-01 00:00:00

  • Safety and effectiveness of Omnitrope® in patients with growth hormone deficiency: snapshot analysis of PATRO Adults study in the Italian population.

    abstract:PURPOSE:PATRO adults is an ongoing, multicenter, observational, post-marketing surveillance study aimed at investigating the long-term safety (primary endpoint) and effectiveness (secondary endpoint) of the recombinant human growth hormone (rhGH) Omnitrope® during routine clinical practice. This report describes data f...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-020-01308-3

    authors: Arosio M,Arnaldi G,Gasco V,Giavoli C,Puxeddu E,Vettor R,Ambrosio MR,Gallinari P,Zouater H,Fedeli P,Ferone D

    更新日期:2021-02-01 00:00:00

  • Relative cardiac expression of growth hormone receptor and insulin-like growth factor-I mRNA in congenital heart disease.

    abstract::GH may exert direct growth-promoting and metabolic actions on target tissues, but most of its effects are mediated by circulating (endocrine) or local (auto-/paracrine) IGF-I. The GH/IGF-I system has an important role in cardiac development and in maintaining the structure and function of the heart. A subgroup of chil...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345590

    authors: Nygren A,Sunnegårdh J,Albertsson-Wikland K,Berggren H,Isgaard J

    更新日期:2008-03-01 00:00:00

  • Occurrence of lymphocyte proliferative response to thyroglobulin and antithyroglobulin antibodies in normal individuals: lack of correlation with HLA.

    abstract::Peripheral mononuclear cells (MNC) of patients with autoimmune thyroid disease have been shown to proliferate when cultured with human thyroglobulin (hTg). In addition, such a phenomenon is apparent in a certain number of healthy individuals. In this study we have attempted to correlate hTg-induced MNC proliferation, ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347192

    authors: Bagnasco M,Orlandini A,Melioli G,Venuti D,Canonica GW,Ferrara GB

    更新日期:1987-04-01 00:00:00

  • Estrogen and progesterone receptors in the human vagina.

    abstract::Estrogen (E) and progesterone (Pg) receptor (R) levels were determined in the human vagina in relation to menopausal status, day of ovarian cycle and pregnancy. The results obtained confirmed that the human vagina contains ER and, in addition, demonstrated for the first time the presence of PgR in this organ in humans...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350667

    authors: Di Carlo F,Racca S,Gallo E,Conti G,Russo A,Mondo F,Francalanci S

    更新日期:1985-04-01 00:00:00