Abstract:
:Hepatitis C virus infection (HCV) is one of the most pressing health emergencies in the world with a global prevalence of about 170 million people chronically infected worldwide. In Europe, Italy has the highest HCV prevalence (3 - 4.4%) with peaks of 12.6 - 26% in Southern regions and the major islands. In Italy HCV genotype 1b prevails, and genotype 4 is mainly found in the south of the country where the prevalence is particularly high in regions such as Calabria.Phylogenetics analysis is a molecular tool widely used to study rapidly-evolving RNA viruses that establish chronic infections such as HCV. Searching the scientific literature, it was found that thirty-nine genetic studies on HCV genotypes have been carried out in Italy between 1997 to 2012 years. However, phylogenetic analysis was performed only in fourteen out of thirty-nine HCV studies (36%) considered. Monitoring the genetic evolution of HCV is an essential step to control the local as well as global HCV epidemic and to develop efficient preventive and therapeutic strategies.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Ciccozzi M,Lo Presti A,Ciccaglione AR,Zehender G,Ciotti Mdoi
10.1186/1471-2334-12-S2-S5subject
Has Abstractpub_date
2012-01-01 00:00:00pages
S5issn
1471-2334pii
1471-2334-12-S2-S5journal_volume
12 Suppl 2pub_type
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pub_type: 杂志文章,已发布勘误
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pub_type: 杂志文章
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更新日期:2017-11-06 00:00:00
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abstract:BACKGROUND:Listeriosis is a severe food-borne infection caused by the Gram-positive rod, Listeria monocytogenes. Despite the low incidence (3-8 cases per million), Listeriosis has a case fatality rate of 20-30% as it occurs predominantly in immunocompromised individuals at extremes of age, diabetics and pregnant women....
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journal_title:BMC infectious diseases
pub_type: 杂志文章
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更新日期:2012-06-20 00:00:00
abstract:BACKGROUND:Over 80% of morbidity due to soil-transmitted helminthiasis (STH) occurs in low-income countries. Children under 5 account for 20-30% of the burden in endemic areas. This study assessed the prevalence, intensity and factors associated with STH infections among preschool-age children (PSAC) in Hoima district,...
journal_title:BMC infectious diseases
pub_type: 杂志文章
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更新日期:2018-08-17 00:00:00
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pub_type: 杂志文章
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更新日期:2019-09-03 00:00:00
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journal_title:BMC infectious diseases
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更新日期:2010-09-10 00:00:00
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pub_type: 杂志文章,随机对照试验
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