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A modified regimen of extracorporeal cardiac shock wave therapy for treatment of coronary artery disease.

Abstract：

BACKGROUND:Cardiac shock wave therapy (CSWT) improves cardiac function in patients with severe coronary artery disease (CAD). We aimed to evaluate the clinical outcomes of a new CSWT treatment regimen. METHODS:The 55 patients with severe CAD were randomly divided into 3 treatment groups. The control group (n = 14) received only medical therapy. In group A ( n = 20), CSWT was performed 3 times within 3 months. In group B ( n = 21), patients underwent 3 CSWT sessions/week, and 9 treatment sessions were completed within 1 month. Primary outcome measurement was 6-minute walk test (6MWT). Other measurements were also evaluated. RESULTS:The 6MWT, CCS grading of angina, dosage of nitroglycerin, NYHA classification, and SAQ scores were improved in group A and B compared to control group. CONCLUSIONS:A CSWT protocol with 1 month treatment duration showed similar therapeutic efficacy compared to a protocol of 3 months duration. CLINICAL TRIAL REGISTRY:We have registered on ClinicalTrials.gov, the protocol ID is CSWT IN CHINA.

journal_name

Cardiovasc Ultrasound

journal_title

Cardiovascular ultrasound

authors

Wang Y,Guo T,Ma TK,Cai HY,Tao SM,Peng YZ,Yang P,Chen MQ,Gu Y

doi

10.1186/1476-7120-10-35

subject

Has Abstract

pub_date

2012-08-17 00:00:00

pages

35

issn

1476-7120

pii

1476-7120-10-35

journal_volume

10

pub_type

杂志文章,随机对照试验

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