Disturbed oscillatory brain dynamics in subcortical ischemic vascular dementia.

abstract：BACKGROUND:The aim of this study was to assess the distribution of key SNARE proteins in glutamatergic and GABAergic synapses of the adult rat cerebellar cortex using light microscopy immunohistochemical techniques. Analysis was made of co-localizations of vGluT-1 and vGluT-2, vesicular transporters of glutamate and ma...

journal_title：BMC neuroscience

authors： Benagiano V,Lorusso L,Flace P,Girolamo F,Rizzi A,Bosco L,Cagiano R,Nico B,Ribatti D,Ambrosi G

更新日期：2011-11-17 00:00:00

abstract：BACKGROUND:This study examined the relationship of the arithmetic mismatch negativity (AMN) and the semantic evaluation of numerical magnitude. The first question was whether the AMN was sensitive to the incongruity in numerical information per se, or rather, to the violation of strategic expectations. The second quest...

journal_title：BMC neuroscience

authors： Hsu YF,Szücs D

更新日期：2011-08-11 00:00:00

abstract：BACKGROUND:To reach and grasp an object in space on the basis of its image cast on the retina requires different coordinate transformations that take into account gaze and limb positioning. Eye position in the orbit influences the image's conversion from retinotopic (eye-centered) coordinates to an egocentric frame nec...

journal_title：BMC neuroscience

authors： Andersson F,Etard O,Denise P,Petit L

更新日期：2004-09-19 00:00:00

abstract：BACKGROUND:Odorant stimuli can access the olfactory epithelium either orthonasally, by inhalation through the external nares, or retronasally by reverse airflow from the oral cavity. There is evidence that odors perceived through these two routes can differ in quality and intensity. We were curious whether such differe...

journal_title：BMC neuroscience

authors： Furudono Y,Cruz G,Lowe G

更新日期：2013-04-08 00:00:00

abstract：BACKGROUND:Previous studies found that rats subjected to carrageenan injection develop hyperalgesia, and despite complete recovery in several days, they continue to have an enhanced hyperalgesic response to a new noxious challenge for more than 28d. The study's aim was to identify candidate genes that have a role in th...

journal_title：BMC neuroscience

authors： Yukhananov R,Kissin I

更新日期：2008-03-13 00:00:00

abstract：BACKGROUND:Parkinson disease (PD) is a movement disorder affecting 1 % of people over the age of 60. The etiology of the disease is unknown; however, accumulating evidence suggests that mitochondrial defects, oxidative stress, and neuroinflammation play important roles in developing the disease. Current medications for...

journal_title：BMC neuroscience

authors： Javed H,Azimullah S,Abul Khair SB,Ojha S,Haque ME

更新日期：2016-08-22 00:00:00

abstract：BACKGROUND:To determine whether early imitative responses fade out following the maturation of attentional mechanisms, the relationship between primitive imitation behaviors and the development of attention was examined in 4-month-old infants. They were divided into high and low imitators, based on an index of imitatio...

journal_title：BMC neuroscience

authors： Nakagawa A,Sukigara M,Benga O

更新日期：2003-12-24 00:00:00

abstract：BACKGROUND:Acute subdural hemorrhage (ASDH) is a severe consequence of traumatic brain injury. The occurrence of subdural blood increases the lethality of these patients independent of the amount of blood or elevated intracranial pressure. Thrombin is one of the potential harmful blood components. Possible harmful effe...

journal_title：BMC neuroscience

authors： Krämer TJ,Sakas W,Jussen D,Krenzlin H,Kempski O,Alessandri B

更新日期：2018-12-27 00:00:00

abstract：BACKGROUND:An individual's ability to recognise and pay attention to others is crucial in order to behave appropriately in various social situations. Studies in humans have shown a sex bias in sociability as well as social memory, indicating that females have better face memory and gaze more at the eyes of others, but ...

journal_title：BMC neuroscience

authors： Karlsson SA,Haziri K,Hansson E,Kettunen P,Westberg L

更新日期：2015-11-25 00:00:00

abstract：BACKGROUND:Receptor-interacting protein 3 (RIP3), a member of RIP family proteins, has been shown to participate in programmed necrosis or necroptosis in cell biology studies. Evidence suggests that necroptosis may be a mode of neuronal death in the retina. RESULTS:In the present study we determined the expression of ...

journal_title：BMC neuroscience

authors： Huang JF,Shang L,Zhang MQ,Wang H,Chen D,Tong JB,Huang H,Yan XX,Zeng LP,Xiong K

更新日期：2013-02-02 00:00:00

abstract：BACKGROUND:Stress involves alterations of brain functioning that may precipitate to mood disorders. The neurotrophin Brain Derived Neurotrophic Factor (BDNF) has recently been involved in stress-induced adaptation. BDNF is a key regulator of neuronal plasticity and adaptive processes. Regulation of BDNF is complex and ...

journal_title：BMC neuroscience

authors： Tognoli C,Rossi F,Di Cola F,Baj G,Tongiorgi E,Terova G,Saroglia M,Bernardini G,Gornati R

更新日期：2010-01-14 00:00:00

abstract：BACKGROUND:Better treatments for schizophrenia are urgently needed. The therapeutic use of the nitric oxide (NO)-donor sodium nitroprusside (SNP) in patients with schizophrenia has shown promising results. The role of NO in schizophrenia is still unclear, and NO modulation is unexplored in ketamine (KET) animal models ...

journal_title：BMC neuroscience

authors： Kandratavicius L,Balista PA,Wolf DC,Abrao J,Evora PR,Rodrigues AJ,Chaves C,Maia-de-Oliveira JP,Leite JP,Dursun SM,Baker GB,Guimaraes FS,Hallak JE

更新日期：2015-03-07 00:00:00

abstract：BACKGROUND:The properties of Ca2+ signaling mediated by purinergic receptors are intrinsically linked with functional activity of astrocytes. At present little is known concerning Ca2+-dependent purinergic responses in adult human astrocytes. This work has examined effects of purinergic stimulation to alter levels of i...

journal_title：BMC neuroscience

authors： Hashioka S,Wang YF,Little JP,Choi HB,Klegeris A,McGeer PL,McLarnon JG

更新日期：2014-01-22 00:00:00

abstract：BACKGROUND:The GABAergic system plays an important role in modulating levels of anxiety. When transplanted into the brain, precursor cells from the medial ganglionic eminence (MGE) have the ability to differentiate into GABAergic interneurons and modify the inhibitory tone in the host brain. Currently, two methods have...

journal_title：BMC neuroscience

authors： Romariz SA,Paiva Dde S,Valente MF,Barnabé GF,Frussa-Filho R,Barbosa-Silva RC,Calcagnotto ME,Longo BM

更新日期：2014-08-02 00:00:00

abstract：BACKGROUND:The potential adverse effect of mobile phone radiation is currently an area of great concern in the field of public health. In the present study, we aimed to investigate the effect of mobile phone radiation (900 MHz radiofrequency) during hatching on postnatal social behaviors in chicks, as well as the effec...

journal_title：BMC neuroscience

authors： Zhou Z,Shan J,Zu J,Chen Z,Ma W,Li L,Xu J

更新日期：2016-06-10 00:00:00

abstract：BACKGROUND:Polymorphisms in the gene for phosphatidylinositol binding clathrin assembly protein (PICALM), an endocytic-related protein, are associated with a small, increased risk of developing Alzheimer's disease (AD), strongly suggesting that changes in endocytosis are involved in the aetiology of the disease. We hav...

journal_title：BMC neuroscience

authors： Thomas RS,Henson A,Gerrish A,Jones L,Williams J,Kidd EJ

更新日期：2016-07-18 00:00:00

abstract：BACKGROUND:The neuropeptide arginine vasopressin (Avp) modulates social behaviors via its two centrally expressed receptors, the Avp 1a receptor and the Avp 1b receptor (Avpr1b). Recent work suggests that, at least in mice, Avp signaling through Avpr1b within the CA2 region of the hippocampus is critical for normal agg...

journal_title：BMC neuroscience

authors： Witchey SK,Stevenson EL,Caldwell HK

更新日期：2016-11-24 00:00:00

abstract：BACKGROUND:The effects of negative emotion on different processing periods in spatial and verbal working memory (WM) and the possible brain mechanism of the interaction between negative emotion and WM were explored using a high-time resolution event-related potential (ERP) technique and time-locked delayed matching-to-...

journal_title：BMC neuroscience

authors： Li X,Chan RC,Luo YJ

更新日期：2010-05-07 00:00:00

abstract：BACKGROUND:Human brain microvascular endothelial cells (hBMVECs) are integral part of the blood brain barrier. Post-translational modifications of adherens junction proteins regulate the permeability of human brain microvascular endothelial cells. Pro-inflammatory signals can induce tyrosine phosphorylation of adherens...

journal_title：BMC neuroscience

authors： Mishra R,Singh SK

更新日期：2014-06-26 00:00:00

abstract：BACKGROUND:Protein aggregation plays important roles in several neurodegenerative disorders. For instance, insoluble aggregates of phosphorylated tau and of Aβ peptides are cornerstones in the pathology of Alzheimer's disease. Soluble protein aggregates are therefore potential diagnostic and prognostic biomarkers for t...

journal_title：BMC neuroscience

authors： Kamali-Moghaddam M,Pettersson FE,Wu D,Englund H,Darmanis S,Lord A,Tavoosidana G,Sehlin D,Gustafsdottir S,Nilsson LN,Lannfelt L,Landegren U

更新日期：2010-10-05 00:00:00

abstract：BACKGROUND:Chlamydophila (Chlamydia) pneumoniae is an intracellular bacterium that has been identified within cells in areas of neuropathology found in Alzheimer disease (AD), including endothelia, glia, and neurons. Depending on the cell type of the host, infection by C. pneumoniae has been shown to influence apoptoti...

journal_title：BMC neuroscience

authors： Appelt DM,Roupas MR,Way DS,Bell MG,Albert EV,Hammond CJ,Balin BJ

更新日期：2008-01-24 00:00:00

abstract：BACKGROUND:A delay in surgical nerve repair results in impaired nerve function in humans, but mechanisms behind the weakened nerve regeneration are not known. Activating transcription factor 3 (ATF3) increases the intrinsic growth state of injured neurons early after injury, but the role of long-term changes and their ...

journal_title：BMC neuroscience

authors： Saito H,Dahlin LB

更新日期：2008-09-18 00:00:00

abstract：BACKGROUND:Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurological pathologies may exacerbate neurodegenerative processes. Accumulating evidence suggests that omega...

journal_title：BMC neuroscience

authors： Zgórzyńska E,Stulczewski D,Dziedzic B,Su KP,Walczewska A

更新日期：2021-01-27 00:00:00

abstract：BACKGROUND:Cys-loop receptors play important roles in fast neuronal signal transmission. Functional receptors are pentamers, with each subunit having an extracellular, transmembrane (TM) and intracellular domain. Each TM domain contains 4 α-helices (M1-M4) joined by loops of varying lengths. Many of the amino acid resi...

journal_title：BMC neuroscience

authors： Tang B,Lummis SCR

更新日期：2018-09-06 00:00:00

abstract：BACKGROUND:Histone deacetylases (HDACs) are enzymes that modulate gene expression and cellular processes by deacetylating histones and non-histone proteins. While small molecule inhibitors of HDAC activity (HDACi) are used clinically in the treatment of cancer, pre-clinical treatment models suggest they also exert neur...

journal_title：BMC neuroscience

authors： Zhou Q,Dalgard CL,Wynder C,Doughty ML

更新日期：2011-05-26 00:00:00

abstract：BACKGROUND:This work examines the central nervous system distribution of virus-labeled neurons from the rat urinary bladder and the prostate simultaneously within the same tissue sections. Two immunohistochemically distinct pseudorabies virus strains were simultaneously injected into male Sprague Dawley rats (approxima...

journal_title：BMC neuroscience

authors： Nadelhaft I,Miranda-Sousa AJ,Vera PL

更新日期：2002-07-12 00:00:00

abstract：BACKGROUND:Multi-sensor technologies such as EEG, MEG, and ECoG result in high-dimensional data sets. Given the high temporal resolution of such techniques, scientific questions very often focus on the time-course of an experimental effect. In many studies, researchers focus on a single sensor or the average over a sub...

journal_title：BMC neuroscience

authors： Schurger A,Marti S,Dehaene S

更新日期：2013-10-14 00:00:00

abstract：BACKGROUND:Multi-sensory integration is necessary for organisms to discriminate different environmental stimuli and thus determine behavior. Caenorhabditis elegans has 12 pairs of amphid sensory neurons, which are involved in generating behaviors such as thermotaxis toward cultivation temperature, and chemotaxis toward...

journal_title：BMC neuroscience

authors： Adachi R,Osada H,Shingai R

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Distinctive patterns of functional connectivity (FC) abnormalities in neural circuitry has been reported in patients with bipolar depression (BD) and unipolar depression (UD). However, it is unclear that whether this distinct functional connectivity patterns are diagnosis specific between BD and UD. This stu...

journal_title：BMC neuroscience

authors： Liu C,Pu W,Wu G,Zhao J,Xue Z

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:To measure the impact of masticatory reduction on learning and memory, previous studies have produced experimental masticatory reduction by modified diet or molar removal. Here we induced spatial learning impairment in mice by reducing masticatory activity and then tested the effect of a combination of envir...

journal_title：BMC neuroscience

authors： Mendes Fde C,de Almeida MN,Felício AP,Fadel AC,Silva Dde J,Borralho TG,da Silva RP,Bento-Torres J,Vasconcelos PF,Perry VH,Ramos EM,Picanço-Diniz CW,Sosthenes MC

更新日期：2013-06-28 00:00:00