Abstract:
:The longitudinal coverage of a LINAC-mounted CBCT scan is limited to the corresponding dimensional limits of its flat panel detector, which is often shorter than the length of the treatment field. These limits become apparent when fields are designed to encompass wide regions, as when providing nodal coverage. Therefore, we developed a novel protocol to acquire double orbit CBCT images using a commercial system, and combine the images to extend the longitudinal coverage for image-guided adaptive radiotherapy (IGART). The protocol acquires two CBCT scans with a couch shift similar to the "step-and-shoot" cine CT acquisition, allowing a small longitudinal overlap of the two reconstructed volumes. An in-house DICOM reading/writing software was developed to combine the two image sets into one. Three different approaches were explored to handle the possible misalignment between the two image subsets: simple stacking, averaging the overlapped volumes, and a 3D-3D image registration with the three translational degrees of freedom. Using thermoluminescent dosimeters and custom-designed holders for a CTDI phantom set, dose measurements were carried out to assess the resultant imaging dose of the technique and its geometric distribution. Deformable registration was tested on patient images generated with the double-orbit protocol, using both the planning FBCT and the artificially deformed CBCT as source images. The protocol was validated on phantoms and has been employed clinically for IRB-approved IGART studies for head and neck and prostate cancer patients.
journal_name
J Appl Clin Med Physjournal_title
Journal of applied clinical medical physicsauthors
Zheng D,Lu J,Jefferson A,Zhang C,Wu J,Sleeman W,Weiss E,Dogan N,Song S,Williamson Jdoi
10.1120/jacmp.v13i4.3796subject
Has Abstractpub_date
2012-07-05 00:00:00pages
3796issue
4issn
1526-9914journal_volume
13pub_type
杂志文章abstract::The purpose of this study was to compare two different styles of prostate IGRT: bony landmark (BL) setup vs. fiducial markers (FM) setup. Twenty-nine prostate patients were treated with daily BL setup and 30 patients with daily FM setup. Delivered dose distribution was reconstructed on cone-beam CT (CBCT) acquired onc...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v14i3.4203
更新日期:2013-05-06 00:00:00
abstract::We investigate the role of adaptive radiation therapy in pediatric patients with diffuse pontine glioma and the impact of steroid-related weight gain on treatment parameters utilizing cone-beam CT. Fifteen patients with diffuse pontine glioma were treated with three-dimensional conformal radiation therapy and enrolled...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:
更新日期:2011-01-30 00:00:00
abstract::The Vero4DRT (MHI-TM2000) is capable of performing X-ray image-based tracking (X-ray Tracking) that directly tracks the target or fiducial markers under continuous kV X-ray imaging. Previously, we have shown that irregular respiratory patterns increased X-ray Tracking errors. Thus, we assumed that audio instruction, w...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v14i5.4488
更新日期:2013-09-06 00:00:00
abstract::Endorectal balloons (ERBs) are routinely used in prostate proton radiation therapy to immobilize the prostate and spare the rectal wall. Rectal gas can distend the rectum and displace the prostate even in the presence of ERBs. The purpose of this work was to quantify the effects an ERB with a passive gas release condu...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i5.3945
更新日期:2012-09-06 00:00:00
abstract::To monitor delivered dose and trigger plan adaptation when deviation becomes unacceptable, a clinical treatment dose (Tx-Dose) reconstruction system based on three-dimensional (3D)/four-dimensional (4D)-cone beam computed tomograpy (CBCT) images was developed and evaluated on various treatment sites, particularly for ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12474
更新日期:2018-11-01 00:00:00
abstract::The purpose of this study was to perform comprehensive measurements and testing of a Novalis Tx linear accelerator, and to develop technical guidelines for com-missioning from the time of acceptance testing to the first clinical treatment. The Novalis Tx (NTX) linear accelerator is equipped with, among other features,...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i3.3729
更新日期:2012-05-10 00:00:00
abstract::This work describes the use of 3D printing technology to create individualized boluses for patients treated with electron beam therapy for skin lesions of the eye canthi. It aimed to demonstrate the effectiveness of 3D-printed over manually fabricated paraffin boluses. The study involved 11 patients for whom the const...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12013
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:The aim of the current study was to evaluate the backscatter dose and energy spectrum from the Lipiodol with flattening filter (FF) and flattening filter-free (FFF) beams. Moreover, the backscatter range, that was defined as the backscatter distance (BD) are revealed. METHODS:6 MVX FF and FFF beams were delive...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12560
更新日期:2019-06-01 00:00:00
abstract::The purpose of this study is to evaluate the accuracy of the electron Monte Carlo (eMC) dose calculation algorithm included in a commercial treatment planning system and compare its performance against an electron pencil beam algorithm. Several tests were performed to explore the system's behavior in simple geometries...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i3.4636
更新日期:2015-05-08 00:00:00
abstract::Significant controversy surrounds the 2012 / 2014 decision announced by the Trustees of the American Board of Radiology (ABR) in October of 2007. According to the ABR, only medical physicists who are graduates of a Commission on Accreditation of Medical Physics Education Programs, Inc. (CAMPEP) accredited academic or ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v11i2.3005
更新日期:2010-04-12 00:00:00
abstract::To improve the penumbra of low-energy beams used in spot-scanning proton therapy, various collimation systems have been proposed and used in clinics. In this paper, focused on patient-specific brass collimators, the collimator-scattered protons' physical and biological effects were investigated. The Geant4 Monte Carlo...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12653
更新日期:2019-07-01 00:00:00
abstract::The nonphysical wedge is a modality that uses computer-controlled jaw motion to generate wedge-shaped dose distributions. There are Varian enhanced dynamic wedges (EDWs) and Siemens virtual wedges (VWs). We recently commissioned dynamic wedges on both Varian and Siemens LINACs. The beam data, acquired with a Wellhofer...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v5i4.1964
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:We conducted this dosimetric analysis to evaluate the feasibility of a multi-center stereotactic body radiation therapy (SBRT) trial for renal cell carcinoma (RCC) using different SBRT platforms. MATERIALS/METHODS:The computed tomography (CT) simulation images of 10 patients with unilateral RCC previously trea...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12308
更新日期:2018-03-14 00:00:00
abstract:PURPOSE:The objective of this study was to evaluate the impact of the magnetic field regulation in conjunction with the volumetric repainting technique on the spot positions and range in pencil beam scanning proton therapy. METHODS:"Field regulation" - a feature to reduce the switching time between layers by applying ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.13045
更新日期:2020-10-15 00:00:00
abstract::We report on initial patient studies to evaluate the performance of a commercial respiratory gating radiotherapy system. The system uses a breathing monitor, consisting of a video camera and passive infrared reflective markers placed on the patient's thorax, to synchronize radiation from a linear accelerator with the ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v2i4.2596
更新日期:2001-10-01 00:00:00
abstract::We investigate the sensitivity of IMRT commissioning using the TG-119 C-shape phantom and credentialing with the IROC head and neck phantom to treatment planning system commissioning errors. We introduced errors into the various aspects of the commissioning process for a 6X photon energy modeled using the analytical a...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i1.5452
更新日期:2016-01-08 00:00:00
abstract::A method to evaluate the electron beam energy constancy by employing the computed radiography (CR) system has been developed. In this method, a right triangular plastic wedge is used to produce a curve of the CR storage phosphor plate signal versus the wedge thickness. The curve, which resembles the percentage depth i...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v10i4.2911
更新日期:2009-10-15 00:00:00
abstract::We clarified the relationship between the display size of MRI images and observer performance using a digital contrast-detail (d-CD) phantom. The d-CD phantom was developed using Microsoft Visual Basic 2010 Express. It had a 512 × 512 matrix in size and a total of 100 holes, whose diameter increased stepwise from 4 to...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i1.5876
更新日期:2016-01-08 00:00:00
abstract::The management of a pregnant patient in radiation oncology is an infrequent event requiring careful consideration by both the physician and physicist. The aim of this manuscript was to highlight treatment planning techniques and detail measurements of fetal dose for a pregnant patient recently requiring treatment for ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12262
更新日期:2018-09-01 00:00:00
abstract::The purpose of this study was to investigate amplitude gating combined with a coached breathing strategy for 10 MV flattening filter-free (FFF) volumetric-modulated arc therapy (VMAT) on the Varian TrueBeam linac. Ten patient plans for VMAT SABR liver were created using the Eclipse treatment planning system (TPS). The...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i4.5350
更新日期:2015-07-08 00:00:00
abstract:PURPOSE:To assess the noise characteristics of the new adaptive statistical iterative reconstruction (ASiR-V) in comparison to ASiR. METHODS:A water phantom was acquired with common clinical scanning parameters, at five different levels of CTDIvol . Images were reconstructed with different kernels (STD, SOFT, and BONE...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12253
更新日期:2018-03-01 00:00:00
abstract::During volume-modulated arc therapies (VMAT), dosimetric errors are introduced by multiple open dynamic leaf gaps that are present in fixed diaphragm linear accelerators. The purpose of this work was to develop a methodology for adjusting the rounded leaf end modeling parameters to improve out-of-field dose agreement ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i6.6343
更新日期:2016-11-08 00:00:00
abstract:PURPOSE:This study evaluates the clinical use of the RUBY modular QA phantom for linac QA to validate the integrity of IGRT workflows including the congruence of machine isocenter, imaging isocenter, and room lasers. The results have been benchmarked against those obtained with widely used systems. Additionally, the RU...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.13006
更新日期:2020-10-01 00:00:00
abstract::The purpose of this study was to describe our experience with 1.0T MR-SIM including characterization, quality assurance (QA) program, and features necessary for treatment planning. Staffing, safety, and patient screening procedures were developed. Utilization of an external laser positioning system (ELPS) and MR-compa...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i2.5201
更新日期:2015-03-08 00:00:00
abstract::The monochromatic images acquired by Gemstone spectral imaging (GSI) mode on the GE CT750 HD theoretically determines the computed tomography (CT) number more accurately than that of conventional scanner. Using the former, the CT number is calculated from (synthesized) monoenergetic X-ray data. We reasoned that the mo...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v14i5.4335
更新日期:2013-09-06 00:00:00
abstract::The purpose of this study was to compare dosimetric parameters of treatment plans among four techniques for preoperative single-fraction partial breast radiotherapy in order to select an optimal treatment technique. The techniques evaluated were noncoplanar 3D conformal radiation therapy (3D CRT), noncoplanar intensit...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i1.5126
更新日期:2015-01-08 00:00:00
abstract::A wide variety of existing combinations of target and filter materials (target/filter combinations) are used in mammography equipment. The patient dose depends on the X-ray quality that is derived from the target/filter combination, and a calibration of the dosimeter that is used in the measurement that corresponds to...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i6.5604
更新日期:2015-11-08 00:00:00
abstract::The purpose of the present study was to use a kilovoltage imaging device to measure interfractional and intrafractional setup deviations in patients with head-and-neck or brain cancers receiving intensity-modulated radiotherapy (IMRT) treatment. Before and after IMRT treatment, approximately 3 times weekly, 7 patients...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v8i4.2439
更新日期:2007-09-24 00:00:00
abstract:PURPOSE:The purpose of this study was to optimize intra-voxel incoherent motion (IVIM) measurement in diffusion-weighted imaging (DWI) of breast cancer by separating perfusion and diffusion effects through the determination of an optimal threshold b-value, thus benign and cancerous breast tissues can be accurately diff...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2017-05-01 00:00:00
abstract::In order to locate lung tumors on kV projection images without internal markers, digitally reconstructed radiographs (DRRs) are created and compared with projection images. However, lung tumors always move due to respiration and their locations change on projection images while they are static on DRRs. In addition, gl...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i3.5200
更新日期:2015-05-08 00:00:00