Performance Comparison of Five SARS-CoV-2 Antibody Assays for Seroprevalence Studies.

abstract：BACKGROUND:Introduction of the Luminex panel reactive antibody (PRA)-single antigen (SA) assay has increased the detection rates of unacceptable antigens in sensitized patients; the calculated PRA (CPRA) level represents the percentage of actual organ donors that express 1 or more of these unacceptable antigens. We dev...

journal_title：Annals of laboratory medicine

authors： Jang JY,Kim YJ,Kim Y,Park YJ,Han K,Oh EJ

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We evaluated the clinical relevance of pretransplant donor-specific HLA antibodies (DSA) in renal transplantation patients who had negative T-cell cytotoxicity crossmatches. METHODS:From 328 consecutive renal transplant recipients, we selected 28 patients who had positive pretransplant (historical or at the...

journal_title：Annals of laboratory medicine

authors： Song EY,Lee YJ,Hyun J,Kim YS,Ahn C,Ha J,Kim SJ,Park MH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Studies that evaluate the effect of age on stone composition are scarce. The aim of this study was to highlight the changes in epidemiological characteristics (stone composition and location) of urolithiasis according to patients' age. METHODS:We studied 1,301 urolithiasis patients with age ranging from 6 m...

journal_title：Annals of laboratory medicine

authors： Alaya A,Nouri A,Belgith M,Saad H,Jouini R,Najjar MF

更新日期：2012-05-01 00:00:00

abstract：:Malaria, the most common vector-borne parasite infection worldwide, results from infection by Plasmodium species. Approximately 80% of malaria cases are caused by P. vivax, which is broadly distributed from tropical to temperate regions; P. falciparum is the second most common infectious species. P. malariae and P. ov...

journal_title：Annals of laboratory medicine

authors： Hong YJ,Yang SY,Lee K,Kim TS,Kim HB,Park KU,Song J,Kim EC

更新日期：2012-05-01 00:00:00

abstract：:MYC rearrangement, a characteristic cytogenetic abnormality of Burkitt lymphoma and several subsets of other mature B-cell neoplasms, typically involves an immunoglobulin gene partner. Herein, we describe a case of precursor B-cell lymphoblastic leukemia harboring a MYC rearrangement with a novel non-immunoglobulin pa...

journal_title：Annals of laboratory medicine

authors： Seo JY,Lee SH,Kim HJ,Yoo KH,Koo HH,Cho YG,Choi SI,Kim SH

更新日期：2012-07-01 00:00:00

abstract：:Infection with Clostridium difficile is a growing concern because of the increasing prevalence and spread of nosocomial infections. Emergence of the hypervirulent 027/NAP1/BI strain is also notable. Existing diagnostic methods have low sensitivity or are time-consuming. Therefore, establishing a rapid and accurate mic...

journal_title：Annals of laboratory medicine

authors： Shin S,Kim M,Kim M,Lim H,Kim H,Lee K,Chong Y

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Treatment for chronic hepatitis B aims to suppress virus replication and virus sequestration in hepatocytes. Covalently closed circular (ccc) DNA is the template for transcription of viral genes and is responsible for viral persistence. However, limited data are available for quantification of hepatitis B su...

journal_title：Annals of laboratory medicine

authors： Lee HJ,Kim SY,Lee SM,Heo J,Kim HH,Chang CL,Lee EY,Son HC

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Group B streptococcus (GBS) infection is a leading cause of neonatal morbidity and mortality worldwide. Here, we present the analytical and diagnostic usefulness of a new real-time PCR-based assay (Xpert GBS; Cepheid, USA) for rapid and accurate prenatal GBS screening. METHODS:We enrolled 175 pregnant women...

journal_title：Annals of laboratory medicine

authors： Park JS,Cho DH,Yang JH,Kim MY,Shin SM,Kim EC,Park SS,Seong MW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The Soonchunhyang University Hospital Bloodless Center was established in 2000, and more than 2,000 bloodless surgeries have been performed there since. In this study, the lowest postoperative Hb/preoperative Hb (Hblow/pre) ratio and mortality rates of patients who underwent bloodless surgery were analyzed f...

journal_title：Annals of laboratory medicine

authors： Jo KI,Shin JW

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:N-ras mutations are one of the most commonly detected abnormalities of myeloid origin. N-ras mutations result in a constitutively active N-ras protein that induces uncontrolled cell proliferation and inhibits apoptosis. We analyzed N-ras mutations in adult patients with AML at a particular institution and co...

journal_title：Annals of laboratory medicine

authors： Jeong JH,Park SH,Park MJ,Kim MJ,Kim KH,Park PW,Seo YH,Lee JH,Park J,Hong J,Ahn JY

更新日期：2013-05-01 00:00:00

abstract：:Li-Fraumeni syndrome (LFS) is a rare, inherited syndrome associated with increased risk of various early-onset tumors. Since the introduction of classic LFS criteria, various criteria have been proposed to include patients with incomplete LFS features, which make up Li-Fraumeni-like syndromes (LFL). Germline missense ...

journal_title：Annals of laboratory medicine

authors： Cho Y,Kim J,Kim Y,Jeong J,Lee KA

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:We evaluated the performance of three chromogenic media (Brilliance agar I [Oxoid, UK], Brilliance agar II [Oxoid], and ChromID MRSA [Biomérieux, France]) combined with broth enrichment and the Xpert MRSA assay for screening of methicillin-resistant Staphylococcus aureus (MRSA). METHODS:We obtained 401 pair...

journal_title：Annals of laboratory medicine

authors： Lee S,Park YJ,Park KG,Jekarl DW,Chae H,Yoo JK,Seo SW,Choi JE,Lim JH,Heo SM,Seo JH

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The urinary iodine micromethod (UIMM) is a modification of the conventional method and its performance needs evaluation. METHODS:UIMM performance was evaluated using the method validation and 2008 Iodine Deficiency Disorders survey data obtained from four urinary iodine (UI) laboratories. Method acceptabili...

journal_title：Annals of laboratory medicine

authors： Hussain H,Khalid NM,Selamat R,Wan Nazaimoon WM

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Early diagnosis of HIV infection reduces morbidity and mortality. Fourth-generation HIV detection assays are more sensitive because they can detect p24 antigen as well as anti-HIV antibodies. In this study, we evaluated the performance of a new fourth-generation ADVIA Centaur HIV antigen/antibody combo (CHIV...

journal_title：Annals of laboratory medicine

authors： Lee K,Park HD,Kang ES

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:We investigated the rates of fecal transmission of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) and carbapenem-resistant Enterobacteriaceae (CRE) among patients admitted to intensive care units (ICUs). METHODS:From June to August 2012, rectal cultures were acquired from all pat...

journal_title：Annals of laboratory medicine

authors： Kim J,Lee JY,Kim SI,Song W,Kim JS,Jung S,Yu JK,Park KG,Park YJ

更新日期：2014-01-01 00:00:00

abstract：:The prevalence of human astroviruses was tested in patients with acute gastroenteritis by using conventional duplex reverse transcription (RT)-PCR and electrophoresis. Diarrheal fecal samples were collected from 9,597 patients at local hospitals in Seoul. The prevalence of astroviruses was 1.0% (94/9,597 patients; mos...

journal_title：Annals of laboratory medicine

authors： Ham H,Oh S,Jang J,Jo S,Choi S,Pak S

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Most mutations in the reverse transcriptase (RT) gene of the hepatitis B virus (HBV) are related to resistance to antiviral agents. Cross-sectional studies on the mutations of this gene are rare. Thus, we analyzed the mutation patterns of RT genes and their biochemical parameters. METHODS:From 2009 to 2012,...

journal_title：Annals of laboratory medicine

authors： Lee AJ,Lee CH,Jeon CH

更新日期：2014-05-01 00:00:00

abstract：:Clinical laboratory tests play an integral role in medical decision-making and as such must be reliable and accurate. Unfortunately, no laboratory tests or devices are foolproof and errors can occur at pre-analytical, analytical and post-analytical phases of testing. Evaluating possible conditions that could lead to e...

journal_title：Annals of laboratory medicine

authors： Njoroge SW,Nichols JH

更新日期：2014-07-01 00:00:00

abstract：:We evaluated the performance of a new chromogenic medium for detection of Clostridium difficile, chromID C. difficile agar (CDIF; bioMérieux, France), by comparison with BBL C. difficile Selective Agar (CDSA; Becton Dickinson and Company, USA). After heat pre-treatment (80℃, 5 min), 185 diarrheal stool samples were in...

journal_title：Annals of laboratory medicine

authors： Han SB,Chang J,Shin SH,Park KG,Lee GD,Park YG,Park YJ

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Measurement of the ABO antibody (Ab) titer is important in ABO-incompatible transplantation. However, to the best of our knowledge, no standard protocol or external survey program to measure the ABO Ab titer has been established in Korea. We investigated the current status of ABO Ab titer measurements at var...

journal_title：Annals of laboratory medicine

authors： Lim YA,Kang SJ

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The present analysis focuses on phenotypic and genotypic characterizations of efflux-mediated erythromycin resistance in Streptococcus pneumoniae due to an increase in macrolide resistance in S. pneumoniae worldwide. METHODS:We investigated the prevalence of efflux-mediated erythromycin resistance and its r...

journal_title：Annals of laboratory medicine

authors： Azadegan A,Ahmadi A,Lari AR,Talebi M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Recurrent somatic SET-binding protein 1 (SETBP1) and splicing pathway gene mutations have recently been found in atypical chronic myeloid leukemia and other hematologic malignancies. These mutations have been comprehensively analyzed in adult AML, but not in childhood AML. We investigated possible alteration...

journal_title：Annals of laboratory medicine

authors： Choi HW,Kim HR,Baek HJ,Kook H,Cho D,Shin JH,Suh SP,Ryang DW,Shin MG

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Establishment of trimester- and assay-specific reference intervals for every population is recommended. The aim of this study was to establish a trimester- and assay-specific reference interval for thyroid-stimulating hormone (TSH) and free thyroxine (FT4) in Korean pregnant women. METHODS:From April 2012 t...

journal_title：Annals of laboratory medicine

authors： Moon HW,Chung HJ,Park CM,Hur M,Yun YM

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Several studies have focused on the association between the lipid-lowering efficacy of statins and the SLCO1B1 c.521T>C polymorphism; however, the results are conflicting. The effects of statins show significant variability between individuals. This meta-analysis aimed to investigate the effects of the SLCO1...

journal_title：Annals of laboratory medicine

authors： Dou Y,Zhu X,Wang Q,Tian X,Cheng J,Zhang E

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:ChromID C. difficile agar (CDIF; bioMérieux, France), a chromogenic medium, allows for the isolation and identification of Clostridium difficile strains within 24 hr regardless of pretreatment of stool specimens with heat or alcohol shock. In the present study, we designed and evaluated a simple procedure fo...

journal_title：Annals of laboratory medicine

authors： Park KS,Ki CS,Lee NY

更新日期：2015-07-01 00:00:00

abstract：:Carbapenemase production has been reported worldwide in gram-negative bacteria, including Acinetobacter species. We detected carbapenemase-producing Acinetobacter pittii in clinical isolates in Daejeon, Korea. Twenty-one ertapenem-resistant A. pittii isolates screened with a disk diffusion method were characterized by...

journal_title：Annals of laboratory medicine

authors： Sung JY,Koo SH,Kim S,Kwon GC

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Several molecular assays have been developed to detect the BRAF V600E mutation in fine needle aspirates (FNAs) for the diagnosis of papillary thyroid cancer. Using a multiplex PCR technique, we evaluated the Anyplex BRAF V600E Real-time Detection (Anyplex) assay and compared its efficacy with that of the See...

journal_title：Annals of laboratory medicine

authors： Choi R,Park KS,Kim JW,Ki CS

更新日期：2015-11-01 00:00:00

abstract：:Mucormycosis, a fatal opportunistic infection in immunocompromised hosts, is caused by fungi belonging to the order Mucorales. Early diagnosis based on exact identification and multidisciplinary treatments is critical. However, identification of Mucorales fungi is difficult and often delayed, resulting in poor prognos...

journal_title：Annals of laboratory medicine

authors： Yang M,Lee JH,Kim YK,Ki CS,Huh HJ,Lee NY

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Extensively drug-resistant (XDR) Pseudomonas aeruginosa and Acinetobacter baumannii are a threat to hospitalized patients. We evaluated the effects of antimicrobial combinations on XDR P. aeruginosa and A. baumannii isolates. METHODS:P. aeruginosa and A. baumannii isolates, which were resistant to all antib...

journal_title：Annals of laboratory medicine

authors： Lee H,Roh KH,Hong SG,Shin HB,Jeong SH,Song W,Uh Y,Yong D,Lee K

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The largest outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection outside Middle East Asia in 2015 has necessitated the rapid expansion of laboratories that conduct MERS-CoV molecular testing in Korea, together with external quality assessment (EQA) to evaluate the assays used. METHO...

journal_title：Annals of laboratory medicine

authors： Seong MW,Lee SJ,Cho SI,Ko K,Kim MN,Sung H,Kim JS,Ahn JS,Yu BS,Kim TS,Kim EC,Park SS

更新日期：2016-05-01 00:00:00