Tired, weak, or in need of rest: fatigue among general practice attenders.

abstract：OBJECTIVE:To investigate the impact of coexistent psychiatric morbidity on risk of suicide after a suicide attempt. DESIGN:Cohort study with follow-up for 21-31 years. SETTING:Swedish national register based study. PARTICIPANTS:39 685 people (53% women) admitted to hospital for attempted suicide during 1973-82. MAI...

journal_title：BMJ (Clinical research ed.)

authors： Tidemalm D,Långström N,Lichtenstein P,Runeson B

更新日期：2008-11-18 00:00:00

abstract：OBJECTIVES:To assess whether supplementation with antioxidants, folinic acid, or both improves the psychomotor and language development of children with Down's syndrome. DESIGN:Randomised controlled trial with two by two factorial design. SETTING:Children living in the Midlands, Greater London, and the south west of ...

journal_title：BMJ (Clinical research ed.)

authors： Ellis JM,Tan HK,Gilbert RE,Muller DP,Henley W,Moy R,Pumphrey R,Ani C,Davies S,Edwards V,Green H,Salt A,Logan S

更新日期：2008-03-15 00:00:00

abstract：:A 40 year old man presents with a 1 cm tender soft swelling in the lateral neck region. This developed seven days after the onset of a tonsillitis episode that has now resolved. He has a 20 pack-year smoking history and consumes minimal alcohol. Examination is otherwise normal. ...

journal_title：BMJ (Clinical research ed.)

authors： Dwivedi RC,Masterson L,Alam M,Jani P

更新日期：2013-10-28 00:00:00

abstract：OBJECTIVE:To assess the waste of research related to inadequate methods in trials included in Cochrane reviews and to examine to what extent this waste could be avoided. A secondary objective was to perform a simulation study to re-estimate this avoidable waste if all trials were adequately reported. DESIGN:Methodolog...

journal_title：BMJ (Clinical research ed.)

authors： Yordanov Y,Dechartres A,Porcher R,Boutron I,Altman DG,Ravaud P

更新日期：2015-03-24 00:00:00

abstract：OBJECTIVE:To describe mortality by suicide and other causes of death in a group of patients who attempted suicide, and to identify predictive factors. DESIGN:10 year follow up study based on records of suicide attempters in 1980. SETTING:Poisoning treatment centre at a general hospital. SUBJECTS:974 patients aged 15...

journal_title：BMJ (Clinical research ed.)

authors： Nordentoft M,Breum L,Munck LK,Nordestgaard AG,Hunding A,Laursen Bjaeldager PA

更新日期：1993-06-19 00:00:00

abstract：OBJECTIVES:To compare the costs of admission to a hospital at home scheme with those of acute hospital admission. DESIGN:Cost minimisation analysis within a pragmatic randomised controlled trial. SETTING:Hospital at home scheme in Leicester and the city's three acute hospitals. PARTICIPANTS:199 consecutive patients ...

journal_title：BMJ (Clinical research ed.)

authors： Jones J,Wilson A,Parker H,Wynn A,Jagger C,Spiers N,Parker G

更新日期：1999-12-11 00:00:00

abstract：OBJECTIVE:To determine whether the link suggested between growth in utero and during infancy and death from cardiovascular disease in men is also present in women. DESIGN:Follow up study of women and men whose birth weight and weight at 1 year of age had been recorded. SETTING:Hertfordshire, England. SUBJECTS:5585 w...

journal_title：BMJ (Clinical research ed.)

authors： Osmond C,Barker DJ,Winter PD,Fall CH,Simmonds SJ

更新日期：1993-12-11 00:00:00

abstract：OBJECTIVE:To design and evaluate a computer advisory system for the treatment of gestational trophoblastic tumour. DESIGN:A comparison of clinicians' treatment decisions with those of the computer system. Two datasets were used: one to calibrate the system and one to independently evaluate it. SETTING:Department of m...

journal_title：BMJ (Clinical research ed.)

authors： Leaning MS,Gallivan S,Newlands ES,Dent J,Brampton M,Smith DB,Bagshawe KD

更新日期：1992-10-03 00:00:00

abstract：OBJECTIVE:To examine the effect of the method of data display on physician investigators' decisions to stop hypothetical clinical trials for an unplanned statistical analysis. DESIGN:Prospective, mixed model design with variables between subjects and within subjects (repeated measures). SETTING:Comprehensive cancer c...

journal_title：BMJ (Clinical research ed.)

authors： Elting LS,Martin CG,Cantor SB,Rubenstein EB

更新日期：1999-06-05 00:00:00

abstract：OBJECTIVE:To investigate the effects of the home environment on the risk of severe asthma during adolescence. DESIGN:A questionnaire based case-control study drawn from a cross sectional survey of allergic diseases among secondary school pupils in Sheffield in 1991. SUBJECTS:763 children whose parents had reported th...

journal_title：BMJ (Clinical research ed.)

authors： Strachan DP,Carey IM

更新日期：1995-10-21 00:00:00

abstract：OBJECTIVES:To determine whether over the counter cough medicines are effective for acute cough in adults. DESIGN:Systematic review of randomised controlled trials. DATA SOURCES:Search of the Cochrane Acute Respiratory Infections Group specialised register, Cochrane Controlled Trials Register, Medline, Embase, and the...

journal_title：BMJ (Clinical research ed.)

authors： Schroeder K,Fahey T

更新日期：2002-02-09 00:00:00

abstract：OBJECTIVES:To evaluate integrated care for diabetes in clinical, psychosocial, and economic terms. DESIGN:Pragmatic randomised trial. SETTING:Hospital diabetic clinic and three general practice groups in Grampian. PATIENTS:274 adult diabetic patients attending a hospital clinic and registered with one of three gener...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1994-05-07 00:00:00

abstract：:In a series of papers published during the past decade Richard Wilkinson has advanced the view that income inequality is the key determinant of variations in average life expectancy at birth among developed countries. Yet a careful examination of the two sources of data on income distribution most often used by Wilkin...

journal_title：BMJ (Clinical research ed.)

authors： Judge K

更新日期：1995-11-11 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of a monovalent rotavirus vaccine against severe rotavirus disease and to assess its impact on diarrhoea in children aged less than 2 years after national introduction in El Salvador, a low-middle income country in Central America. DESIGN:Matched case-control study. SETTING:Sev...

journal_title：BMJ (Clinical research ed.)

authors： de Palma O,Cruz L,Ramos H,de Baires A,Villatoro N,Pastor D,de Oliveira LH,Kerin T,Bowen M,Gentsch J,Esposito DH,Parashar U,Tate J,Patel M

更新日期：2010-06-15 00:00:00

abstract：OBJECTIVE:To assess relative efficacy and toxicity of aminoglycosides given by single daily dose compared with multiple daily doses. DESIGN:Meta-analysis of 21 randomised trials identified through MEDLARS (1966 to January 1995). Data were overviewed with fixed effects and random effects models and with meta-regression...

journal_title：BMJ (Clinical research ed.)

authors： Barza M,Ioannidis JP,Cappelleri JC,Lau J

更新日期：1996-02-10 00:00:00

abstract：OBJECTIVE:To investigate the clinical effects of regulating umbilical cord clamping in preterm infants. DESIGN:A prospective randomised study. SETTING:The Queen Mother's Hospital, Glasgow. SUBJECTS:36 vaginally delivered infants over 27 and under 33 weeks' gestation. INTERVENTION:Holding the infant 20 cm below the ...

journal_title：BMJ (Clinical research ed.)

authors： Kinmond S,Aitchison TC,Holland BM,Jones JG,Turner TL,Wardrop CA

更新日期：1993-01-16 00:00:00

abstract：OBJECTIVE:To prepare and assess the sensitivity and specificity of a latex agglutination test specific for the serotype of antigen in diagnosing pneumococcal pneumonia in Gambian children. DESIGN:Comparison of agglutination test specific for serotype with culture of blood and lung aspirates, countercurrent immunoelect...

journal_title：BMJ (Clinical research ed.)

authors： O'Neill KP,Lloyd-Evans N,Campbell H,Forgie IM,Sabally S,Greenwood BM

更新日期：1989-04-22 00:00:00

abstract：OBJECTIVE:To evaluate whether follow up of patients with inflammatory bowel disease is better through open access than by routine booked appointments. DESIGN:Pragmatic randomised controlled trial. SETTING:Two district general hospitals in Swansea and Neath, Wales. PARTICIPANTS:180 adults (78 with Crohn's disease, 77...

journal_title：BMJ (Clinical research ed.)

authors： Williams JG,Cheung WY,Russell IT,Cohen DR,Longo M,Lervy B

更新日期：2000-02-26 00:00:00

abstract：OBJECTIVE:To examine whether the risk of breast cancer is increased by a recent term pregnancy. DESIGN:Population based case-control study. SETTING:Eight areas in the United States. SUBJECTS:Cases were 2279 multiparous women residents of the eight areas aged 25-49 who were diagnosed as having breast cancer during 19...

journal_title：BMJ (Clinical research ed.)

authors： Cummings P,Stanford JL,Daling JR,Weiss NS,McKnight B

更新日期：1994-06-25 00:00:00

abstract：OBJECTIVES:To understand the approaches to learning of practising physicians in their workplace and to assess the relation of these approaches to their motivation for, preferred methods of, and perceived barriers to continuing medical education. DESIGN:Postal survey of 800 Ontario physicians. PARTICIPANTS:373 physici...

journal_title：BMJ (Clinical research ed.)

authors： Delva MD,Kirby JR,Knapper CK,Birtwhistle RV

更新日期：2002-11-23 00:00:00

abstract：OBJECTIVE:To systematically evaluate the published evidence regarding the characteristics and effectiveness of disease management programmes. DESIGN:Meta-analysis. DATA SOURCES:Computerised databases for English language articles during 1987-2001. STUDY SELECTION:102 articles evaluating 118 disease management progra...

journal_title：BMJ (Clinical research ed.)

authors： Weingarten SR,Henning JM,Badamgarav E,Knight K,Hasselblad V,Gano A Jr,Ofman JJ

更新日期：2002-10-26 00:00:00

abstract：OBJECTIVE:To investigate the variation in prescribing among general practices by examining the contribution to this variation of fundholding, training status, partnership status, and the level of deprivation in the practice population and to investigate the extent to which fundholding has been responsible for any chang...

journal_title：BMJ (Clinical research ed.)

authors： Wilson RP,Hatcher J,Barton S,Walley T

更新日期：1996-09-07 00:00:00

abstract：OBJECTIVES:To investigate the effect of Chlamydia pneumoniae infection on future development of ischaemic heart disease and mortality. DESIGN:Prospective longitudinal study. SETTING:Caerphilly, South Wales. SUBJECTS:Plasma specimens were collected during 1979-83 from 1773 men aged 45-59 years. These were tested for ...

journal_title：BMJ (Clinical research ed.)

authors： Strachan DP,Carrington D,Mendall MA,Ballam L,Morris J,Butland BK,Sweetnam PM,Elwood PC

更新日期：1999-04-17 00:00:00

abstract：OBJECTIVE:To determine whether low dose aspirin protects women aged 65 or more against cognitive decline. DESIGN:Cohort study within both arms of the women's health study, a randomised, double blind, placebo controlled trial of low dose aspirin for the primary prevention of cardiovascular disease and cancer, 1992-5. ...

journal_title：BMJ (Clinical research ed.)

authors： Kang JH,Cook N,Manson J,Buring JE,Grodstein F

更新日期：2007-05-12 00:00:00

abstract：OBJECTIVE:To compare incidences of perinatal mortality and severe perinatal morbidity between low risk term pregnancies supervised in primary care by a midwife and high risk pregnancies supervised in secondary care by an obstetrician. DESIGN:Prospective cohort study using aggregated data from a national perinatal regi...

journal_title：BMJ (Clinical research ed.)

authors： Evers AC,Brouwers HA,Hukkelhoven CW,Nikkels PG,Boon J,van Egmond-Linden A,Hillegersberg J,Snuif YS,Sterken-Hooisma S,Bruinse HW,Kwee A

更新日期：2010-11-02 00:00:00

abstract：OBJECTIVE:To determine the efficacy and safety of the anticoagulant fondaparinux in older acute medical inpatients at moderate to high risk of venous thromboembolism. DESIGN:Double blind randomised placebo controlled trial. SETTING:35 centres in eight countries. PARTICIPANTS:849 medical patients aged 60 or more admi...

journal_title：BMJ (Clinical research ed.)

authors： Cohen AT,Davidson BL,Gallus AS,Lassen MR,Prins MH,Tomkowski W,Turpie AG,Egberts JF,Lensing AW,ARTEMIS Investigators.

更新日期：2006-02-11 00:00:00

abstract：:The issue of children on hunger strike (voluntary total fasting) has not been reported before. The World Medical Association Declaration of Tokyo 1975 and the Declaration of Malta 1991 (revised 1992) provide clinicians with guidelines for the management of adult patients on hunger strike but do not mention children. W...

journal_title：BMJ (Clinical research ed.)

authors： Mok A,Nelson EA,Murphy J,Hampson A,Hendriks JH

更新日期：1996-02-24 00:00:00

abstract：OBJECTIVES:To investigate patients' and family members' perceptions and experiences of disclosure of healthcare incidents and to derive principles of effective disclosure. DESIGN:Retrospective qualitative study based on 100 semi-structured, in depth interviews with patients and family members. SETTING:Nationwide mult...

journal_title：BMJ (Clinical research ed.)

authors： Iedema R,Allen S,Britton K,Piper D,Baker A,Grbich C,Allan A,Jones L,Tuckett A,Williams A,Manias E,Gallagher TH

更新日期：2011-07-25 00:00:00

abstract：OBJECTIVE:To derive and validate an algorithm to estimate the absolute risk of having ovarian cancer in women with and without symptoms. DESIGN:Cohort study with data from 375 UK QResearch general practices for development and 189 for validation. PARTICIPANTS:Women aged 30-84 without a diagnosis of ovarian cancer at ...

journal_title：BMJ (Clinical research ed.)

authors： Hippisley-Cox J,Coupland C

更新日期：2011-01-04 00:00:00

abstract：:The studyA Rodger, V Cambiano, T Bruun, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet 2019;393:2428-38.This project was funde...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Davidson P,clinical adviser,.,Martin R,NIHR Dissemination Centre.

更新日期：2019-08-27 00:00:00