Glucagon test in insulinoma: Is it useful?

Abstract:

:Diagnosis of endogenous hyperinsulinism caused by insulinoma is based on confirmation of hypoglycemia during the symptoms associated to elevated insulin levels. Patients with insulinoma may demonstrate an excessive insulin response and subsequent hypoglycemia after 1 mg of glucagon iv injection. Glucagon test was performed in 11 patients with insulinoma before therapy and in 4 after therapy. Our study suggests that the presence of plasma glucose levels less than 55 mg/dl and below baseline at time 120 min of glucagon test strongly reinforce the diagnosis of insulinoma.

journal_name

J Endocrinol Invest

authors

Felício JS,Martins CL,Mileo KB,Semer M,Kalinin L,Nery M,Machado MC,Liberman B

doi

10.3275/7879

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

570-2

issue

6

eissn

0391-4097

issn

1720-8386

pii

7879

journal_volume

35

pub_type

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