当前位置： SCI文献检索 > BMC GASTROENTEROLOGY期刊下所有文献 > The prevalence, incidence and natural history of primary sclerosing cholangitis in an ethnically diverse population.

The prevalence, incidence and natural history of primary sclerosing cholangitis in an ethnically diverse population.

Abstract：

BACKGROUND:Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic liver disease often associated with inflammatory bowel diseases (IBD). Current epidemiological data are limited to studies of predominantly Caucasian populations. Our aim was to define the epidemiology of PSC in a large, ethnically diverse US population. METHODS:The Northern California Kaiser Permanente (KP) database includes records from over 3 million people and was searched for cases of PSC between January 2000 and October 2006. All identified charts were reviewed for diagnosis confirmation, IBD co-morbidity, and major natural history endpoints. RESULTS:We identified 169 (101 males) cases fulfilling PSC diagnostic criteria with a mean age at diagnosis of 44 years (range 11-81). The age-adjusted point prevalence was 4.15 per 100,000 on December 31, 2005. The age-adjusted incidence per 100,000 person-years was not significantly greater in men 0.45 (95% CI 0.33-0.61) than women 0.37 (95% CI 0.26-0.51). IBD was present in 109/169 (64.5%) cases and was significantly more frequent in men than women with PSC (73.3% and 51.5%, respectively, p = 0.005). The cumulative average yearly mortality rate was 1.9%. Age and serum sodium, creatinine and bilirubin at diagnosis and albumin at last entry were identified as significant factors associated with death, liver transplant or cholangiocarcinoma. CONCLUSIONS:The incidence and prevalence of PSC observed in a representative Northern California population are lower compared to previous studies in Caucasian populations and this might reflect differences in the incidence of PSC among various ethnic groups.

journal_name

BMC Gastroenterol

journal_title

BMC gastroenterology

authors

Toy E,Balasubramanian S,Selmi C,Li CS,Bowlus CL

doi

10.1186/1471-230X-11-83

subject

Has Abstract

pub_date

2011-07-18 00:00:00

pages

83

issn

1471-230X

pii

1471-230X-11-83

journal_volume

11

pub_type

杂志文章

相关文献

BMC GASTROENTEROLOGY文献大全
  • Trends in gastroenteritis-associated mortality in the United States, 1985-2005: variations by ICD-9 and ICD-10 codes.

    abstract：BACKGROUND:Trends in gastroenteritis-associated mortality are changing over time with development of antibiotic resistant strains of certain pathogens, improved diagnostic methods, and changing healthcare. In 1999, ICD-10 coding was introduced for mortality records which can also affect trends. We assess trends in gast...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-014-0211-0

    authors： Jagai JS,Smith GS,Schmid JE,Wade TJ

    更新日期：2014-12-10 00:00:00

  • Possible role of Escherichia coli in propagation and perpetuation of chronic inflammation in ulcerative colitis.

    abstract：BACKGROUND:This study investigated a possible role of Escherichia coli in propagation and perpetuation of the chronic inflammation in ulcerative colitis (UC). The lesions of UC are located superficially on the rectal and/or colonic mucosa. It is suggested that the commensal bacteria of the digestive tract may play a ro...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/1471-230X-13-61

    authors： Pilarczyk-Zurek M,Chmielarczyk A,Gosiewski T,Tomusiak A,Adamski P,Zwolinska-Wcislo M,Mach T,Heczko PB,Strus M

    更新日期：2013-04-08 00:00:00

  • Leukocytoclastic vasculitis as a rare dermatologic manifestation of Crohn's disease mimicking cellulitis: a case report.

    abstract：BACKGROUND:Leukocytoclastic vasculitis (LCV) is an immune-complex mediated vasculitis characterized by neutrophilic inflammation and nuclear debris in post capillary venules. LCV is a rare dermatologic manifestation of Crohn's disease (CD) and may occur with the onset of the disease or any time after the diagnosis incl...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-020-01371-3

    authors： Buck M,Dumic I,McDermott W,Nordstrom C,Dawan S,Virata A,Martin S,Hudson A,Milovanovic T,Nordin T

    更新日期：2020-07-29 00:00:00

  • A rapid, simple questionnaire to assess gastrointestinal symptoms after oral ferrous sulphate supplementation.

    abstract：BACKGROUND:Oral iron supplementation is often associated with rapid onset of gastrointestinal side-effects. The aim of this study was to develop and trial a short, simple questionnaire to capture these early side-effects and to determine which symptoms are more discriminating. METHODS:The study was a double-blind plac...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,随机对照试验

    doi：10.1186/1471-230X-14-103

    authors： Pereira DI,Couto Irving SS,Lomer MC,Powell JJ

    更新日期：2014-06-04 00:00:00

  • Fecal lactoferrin in discriminating inflammatory bowel disease from irritable bowel syndrome: a diagnostic meta-analysis.

    abstract：BACKGROUND:To perform a meta-analysis evaluating the diagnostic ability of fecal lactoferrin (FL) to distinguish inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS). METHODS:The Medline, EMBASE, Web of Science, Cochrane library and CNKI databases were systematically searched for studies that used FL c...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1186/1471-230X-14-121

    authors： Zhou XL,Xu W,Tang XX,Luo LS,Tu JF,Zhang CJ,Xu X,Wu QD,Pan WS

    更新日期：2014-07-07 00:00:00

  • Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study.

    abstract：BACKGROUND:Intestinal metaplasia (IM) is an important precursor lesion in the development of gastric cancer (GC). The aim of this study was to investigate genetic factors previously linked to GC risk for their possible association with IM. A total of 18 polymorphisms in 14 candidate genes were evaluated in a Singapore-...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/1471-230X-9-76

    authors： Zhu F,Loh M,Hill J,Lee S,Koh KX,Lai KW,Salto-Tellez M,Iacopetta B,Yeoh KG,Soong R,Singapore Gastric Cancer Consortium.

    更新日期：2009-10-13 00:00:00

  • Chronic active EBV infection in refractory enteritis with longitudinal ulcers with a cobblestone appearance: an autopsied case report.

    abstract：BACKGROUND:Chronic active Epstein-Barr virus infection (CAEBV) is defined as Epstein-Barr virus (EBV)-positive T/NK cell-related neoplasia, and its major clinical symptom is systemic inflammation presenting as infectious mononucleocytosis, whereas enteritis and diarrhea are minor clinical symptoms. The complex mixture ...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-020-01589-1

    authors： Aihara Y,Moriya K,Shimozato N,Nagamatsu S,Kobayashi S,Uejima M,Matsuo H,Ishida E,Yagi H,Nakatani T,Yoshiji H,Kikuchi E

    更新日期：2021-01-06 00:00:00

  • Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH.

    abstract：BACKGROUND:The ideal medication for acid-related diseases should have a rapid onset of action to promote hemostasis and cause efficient resolution of symptoms. The aim of our study was to comparatively investigate the inhibitory effect on gastric acid secretion of a single oral administration of omeprazole plus mosapri...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,随机对照试验

    doi：10.1186/1471-230X-12-25

    authors： Iida H,Inamori M,Fujii T,Sekino Y,Endo H,Hosono K,Nonaka T,Koide T,Takahashi H,Yoneda M,Goto A,Abe Y,Kobayashi N,Kirikoshi H,Kubota K,Saito S,Gotoh E,Maeda S,Nakajima A

    更新日期：2012-03-26 00:00:00

  • Transarterial chemoembolization plus sorafenib for the management of unresectable hepatocellular carcinoma: a systematic review and meta-analysis.

    abstract：BACKGROUND:Transarterial chemoembolization (TACE) is the recommended treatment for hepatocellular carcinoma (HCC) patients at Barcelona Clinic Liver Cancer (BCLC) B-stage, whereas sorafenib is an orally administered small molecule target drug for BCLC C-stage. This updated systemic review and meta-analysis focuses on i...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1186/s12876-018-0849-0

    authors： Li L,Zhao W,Wang M,Hu J,Wang E,Zhao Y,Liu L

    更新日期：2018-09-04 00:00:00

  • Desmoid tumors complicating Familial Adenomatous Polyposis: a meta-analysis mutation spectrum of affected individuals.

    abstract：BACKGROUND:Desmoid tumors are a group of benign, invasive, solid tumors that are relatively rare in the general population, but can occur in up to 21 % of patients with Familial Adenomatous Polyposis (FAP). They can be difficult to treat and have high rates of recurrence even after resection. Our goal with this study w...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,meta分析

    doi：10.1186/s12876-015-0306-2

    authors： Slowik V,Attard T,Dai H,Shah R,Septer S

    更新日期：2015-07-16 00:00:00

  • Fluoroless intravascular ultrasound image-guided liver navigation in porcine models.

    abstract：BACKGROUND:An intravascular ultrasound catheter (IVUSc) was developed for intracardiac ultrasound to assess interventions with compelling results. However, intrahepatic vascular exploration was rarely tested and was always associated with X-ray techniques. The aim of this study was to demonstrate the feasibility to nav...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-021-01600-3

    authors： Urade T,Verde JM,García Vázquez A,Gunzert K,Pessaux P,Marescaux J,Giménez ME

    更新日期：2021-01-09 00:00:00

  • Ferritin above 100 mcg/L could rule out colon cancer, but not gastric or rectal cancer in patients with involuntary weight loss.

    abstract：BACKGROUND:A tenth of patients with involuntary weight loss (IWL) have gastrointestinal cancer. Ferritin is the first parameter to be modified during the process leading to iron deficiency anaemia, therefore it should be the most sensitive. The aim of this study was to assess the ability of ferritin to rule out gastroi...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/1471-230X-12-86

    authors： Baicus C,Caraiola S,Rimbas M,Patrascu R,Baicus A,GSSPI.

    更新日期：2012-07-09 00:00:00

  • Pancreatic duct guidewire placement for biliary cannulation as a risk factor for stone residue after endoscopic transpapillary stone removal.

    abstract：BACKGROUND:Recent improvements in stone extraction implements and apparatus have lessened the complexity of the endoscopic bile duct stone treatment. However, despite confirmation of complete removal, cases of residual stones have been reported, which can result in recurrent biliary symptoms, cholangitis, and pancreati...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-020-01428-3

    authors： Fujita A,Nakahara K,Michikawa Y,Morita R,Suetani K,Sato J,Igarashi Y,Araki R,Ikeda H,Matsunaga K,Watanabe T,Itoh F

    更新日期：2020-08-24 00:00:00

  • Health education program improves QOL in students with irritable bowel syndrome after the Wenchuan earthquake: a five-year multi-center study.

    abstract：BACKGROUND:Stress is a common contributing factor for irritable bowel syndrome (IBS). This study was to evaluate the efficacy of the centralized health education program in improving the quality of life (QOL) of middle school students with IBS who experienced the Wenchuan earthquake on May 12, 2008. METHODS:A multi-ce...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1186/s12876-018-0845-4

    authors： Zheng SC,Gong H,Wang YP,Zhang Q,Wang LL,Liao XF,He DW,Wu J

    更新日期：2018-07-27 00:00:00

  • Real life results in using 5-ASA for maintaining mild to moderate UC patients in Japan, a multi-center study, OPTIMUM Study.

    abstract：BACKGROUND:Efficacy of maintenance therapy in ulcerative colitis (UC) in the remission stage has been reported to depend on release profile or dosing regimen of oral 5-aminosalicylic acid (5-ASA) products used. Aim of this study is to investigate real life results in using oral 5-ASA products for maintaining mild to mo...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,多中心研究

    doi：10.1186/s12876-017-0604-y

    authors： Nagahori M,Kochi S,Hanai H,Yamamoto T,Nakamura S,Omuro S,Watanabe M,Hibi T,OPTIMUM Study Group.

    更新日期：2017-04-04 00:00:00

  • Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas harboring KRAS and BRCA mutations: case report and whole exome sequencing analysis.

    abstract：BACKGROUND:Undifferentiated carcinoma with osteoclast-like giant cells (UC-OGC) is an extremely uncommon pancreatic neoplasm that comprises less than 1% of all exocrine pancreatic tumors. To date, cases and data from whole-exome sequencing (WES) analysis have been reported by specific studies. We report a case of pancr...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-020-01351-7

    authors： Yang G,Yin J,Ou K,Du Q,Ren W,Jin Y,Peng L,Yang L

    更新日期：2020-06-26 00:00:00

  • Medication beliefs among patients with inflammatory bowel disease who report low quality of life: a qualitative study.

    abstract：BACKGROUND:Non-adherence to drug therapy is common in Inflammatory Bowel Disease (IBD). Patients' beliefs about treatment have an important influence on adherence. An in-depth understanding of this area is, therefore, important for patient-centred care. The aim of the study was to assess patients' perspectives and beli...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/1471-230X-7-20

    authors： Hall NJ,Rubin GP,Hungin AP,Dougall A

    更新日期：2007-06-08 00:00:00

  • "Sarcopenia and intramuscular fat deposition are associated with poor survival in Indonesian patients with hepatocellular carcinoma: a retrospective study".

    abstract：BACKGROUND:A large-scale Japanese study showed that low skeletal muscle index (SMI) and intramuscular fat (IMF) deposition are associated with hepatocellular carcinoma (HCC) survival. Here, we evaluated the effects of SMI and IMF on the survival of Indonesian HCC patients, whose characteristics differ from those of Jap...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-019-1152-4

    authors： Mardian Y,Yano Y,Ratnasari N,Choridah L,Wasityastuti W,Setyawan NH,Hayashi Y

    更新日期：2019-12-30 00:00:00

  • A multi-country study of intussusception in children under 2 years of age in Latin America: analysis of prospective surveillance data.

    abstract：BACKGROUND:Intussusception (IS) is a form of acute intestinal obstruction that occurs mainly in infants and is usually of unknown cause. An association between IS and the first licensed rotavirus vaccine, a reassortant-tetravalent, rhesus-based rotavirus vaccine (RRV-TV), led to the withdrawal of the vaccine. New rotav...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/1471-230X-13-95

    authors： Sáez-Llorens X,Velázquez FR,Lopez P,Espinoza F,Linhares AC,Abate H,Nuñez E,Venegas G,Vergara R,Jimenez AL,Rivera M,Aranza C,Richardson V,Macias-Parra M,Palacios GR,Rivera L,Ortega-Barria E,Cervantes Y,Rüttimann R,Ru

    更新日期：2013-05-27 00:00:00

  • Deficiency of iNOS-derived NO accelerates lipid accumulation-independent liver fibrosis in non-alcoholic steatohepatitis mouse model.

    abstract：BACKGROUND:Although many of the factors and molecules closely associated with non-alcoholic steatohepatitis (NASH) have been reported, the role of inducible nitric oxide synthase (iNOS)-derived nitric oxide (NO) on the progression of NASH remains unclear. We therefore investigated the role of iNOS-derived NO in NASH pa...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-015-0269-3

    authors： Nozaki Y,Fujita K,Wada K,Yoneda M,Kessoku T,Shinohara Y,Imajo K,Ogawa Y,Nakamuta M,Saito S,Masaki N,Nagashima Y,Terauchi Y,Nakajima A

    更新日期：2015-04-01 00:00:00

  • Variables affecting penetrance of gastric and duodenal phenotype in familial adenomatous polyposis patients.

    abstract：BACKGROUND:Patients with familial adenomatous polyposis (FAP) frequently undergo colectomy to reduce the 70 to 90% lifetime risk of colorectal cancer. After risk-reducing colectomy, duodenal cancer and complications from duodenal surgeries are the main cause of morbidity. Our objective was to prospectively describe the...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-018-0841-8

    authors： Sample DC,Samadder NJ,Pappas LM,Boucher KM,Samowitz WS,Berry T,Westover M,Nathan D,Kanth P,Byrne KR,Burt RW,Neklason DW

    更新日期：2018-07-16 00:00:00

  • Sleep problems and functional disability in children with functional gastrointestinal disorders: an examination of the potential mediating effects of physical and emotional symptoms.

    abstract：BACKGROUND:Sleep disturbances are increasingly recognized as a common problem for children and adolescents with chronic pain conditions, but little is known about the prevalence, type, and impact of sleep problems in pediatric functional gastrointestinal disorders (FGIDs). The objectives of the current study were two-f...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/1471-230X-12-142

    authors： Schurman JV,Friesen CA,Dai H,Danda CE,Hyman PE,Cocjin JT

    更新日期：2012-10-15 00:00:00

  • Possible etiology of improvements in both quality of life and overlapping gastroesophageal reflux disease by proton pump inhibitor treatment in a prospective randomized controlled trial.

    abstract：BACKGROUND:Symptoms suggestive of functional dyspepsia (FD) and irritable bowel syndrome (IBS) frequently overlap with those of gastroesophageal reflux disease. Despite the high prevalence of symptomatic overlap, the underlying etiology remains poorly defined. We assessed the correlation of symptomatic relief and healt...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1186/1471-230X-13-145

    authors： Mönnikes H,Schwan T,van Rensburg C,Straszak A,Theek C,Lühmann R,Sander P,Tholen A

    更新日期：2013-10-01 00:00:00

  • Folate levels in hepatocellular carcinoma patients with portal vein thrombosis.

    abstract：BACKGROUND:Portal vein thrombosis (PVT) occurs frequently in hepatocellular carcinoma (HCC) and is often diagnosed in the course of a routine patient evaluation and surveillance for liver cancer. The purpose of this study is to investigate the relationship between folate status and portal vein thrombosis. METHODS:HCC ...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-020-01525-3

    authors： Malaguarnera G,Catania VE,Latteri S,Borzì AM,Bertino G,Madeddu R,Drago F,Malaguarnera M

    更新日期：2020-11-10 00:00:00

  • The association of hepatitis c virus infection status with serum glucose levels.

    abstract：BACKGROUND:Hepatitis C virus (HCV) infection is commonly associated with a disturbance of glucose metabolism. However, there have been conflicting reports on whether the clearance of the HCV may be followed by changes of serum blood glucose and insulin resistance. The aim of the present study was to evaluate the impact...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-019-1003-3

    authors： Li Y,Wang X,Yu G,Sun H,Lv J,Chi X,Wu R,Gao X,Niu J

    更新日期：2019-06-13 00:00:00

  • Intrahepatic cholestasis of pregnancy: observational study of the treatment with low-dose ursodeoxycholic acid.

    abstract：BACKGROUND:To exam the biochemical, obstetric management and pregnancy outcome in women with intrahepatic cholestasis of pregnancy (ICP) and treatment with ursodeoxycholic acid (UDCA). METHODS:Pregnancy outcome in patients with ICP (N = 307) was studied and patients treated with UDCA (N = 208) vs. no UDCA were compare...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-015-0324-0

    authors： Joutsiniemi T,Timonen S,Linden M,Suvitie P,Ekblad U

    更新日期：2015-07-29 00:00:00

  • Low bone mass in microscopic colitis.

    abstract：BACKGROUND:Microscopic colitis presents with similar symptoms to classic inflammatory bowel diseases. Osteoporosis is a common complication of Crohn's disease but there are no data concerning bone metabolism in microscopic colitis. AIMS:The aim of the present study was to evaluate bone density and metabolism in patien...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/1471-230X-11-58

    authors： Lorinczy K,Lakatos G,Müllner K,Hritz I,Lakatos PL,Tulassay Z,Miheller P

    更新日期：2011-05-19 00:00:00

  • Short chain fatty acids and colon motility in a mouse model of irritable bowel syndrome.

    abstract：BACKGROUND:Irritable bowel syndrome (IBS) is defined as a multifactorial disorder associated with visceral hypersensitivity, altered gut motility and dysfunction of the brain-gut axis. Gut microbiota and its metabolites are proposed as possible etiological factors of IBS. Short chain fatty acids (SCFAs) induce both inh...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/s12876-021-01613-y

    authors： Shaidullov IF,Sorokina DM,Sitdikov FG,Hermann A,Abdulkhakov SR,Sitdikova GF

    更新日期：2021-01-26 00:00:00

  • Acupuncture for irritable bowel syndrome: a protocol for a pragmatic randomised controlled trial.

    abstract：BACKGROUND:There is insufficient evidence on the effectiveness of acupuncture for irritable bowel syndrome (IBS) for conclusions to be drawn. Given the current interest in acupuncture by patients, it is in the public interest to establish more rigorous evidence. Building on the positive findings from a pilot study, in ...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章,随机对照试验

    doi：10.1186/1471-230X-10-63

    authors： MacPherson H,Bland M,Bloor K,Cox H,Geddes D,Kang'ombe A,Reynolds J,Stamuli E,Stuardi T,Tilbrook H,Torgerson D,Whorwell P

    更新日期：2010-06-17 00:00:00

  • Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study.

    abstract：BACKGROUND:The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with chronic gastritis and peptic ulcers. This paper focuses on comparing HRQOL in patients with chronic ga...

    journal_title：BMC gastroenterology

    pub_type： 杂志文章

    doi：10.1186/1471-230X-14-149

    authors： Wen Z,Li X,Lu Q,Brunson J,Zhao M,Tan J,Wan C,Lei P

    更新日期：2014-08-20 00:00:00