Abstract:
:Spinal cord injury (SCI) research is a very complex field lending to why reviews of SCI literatures can be beneficial to current and future researchers. This review focuses on recent articles regarding potential modalities for the treatment and management of SCI. The modalities were broken down into four categories: neuroprotection-pharmacologic, neuroprotection-non-pharmacologic, neuroregeneration-pharmacologic, neuroregeneration-non-pharmacologic. Peer-reviewed articles were found using PubMed with search terms: "spinal cord injury", "spinal cord injury neuroregeneration", "olfactory ensheathing cells spinal cord injury", "rho-rock inhibitors spinal cord injury", "neural stem cell", "scaffold", "neural stem cell transplantation", "exosomes and SCI", "epidural stimulation SCI", "brain-computer interfaces and SCI". Most recent articles spanning two years were chosen for their relevance to the categories of SCI management and treatment. There has been a plethora of pre-clinical studies completed with their results being difficult to replicate in clinical studies. Therefore, scientists should focus on understanding and applying the results of previous research to develop more efficacious preclinical studies and clinical trials.
journal_name
Neural Regen Resjournal_title
Neural regeneration researchauthors
Flack JA,Sharma KD,Xie JYdoi
10.4103/1673-5374.317961keywords:
["brain-computer interface","epidural stimulation","exosomes","neuroprotection","neuroregeneration","scaffolds","spinal cord injury management","stem cells","transplantation"]subject
Has Abstractpub_date
2022-02-01 00:00:00pages
283-291issue
2eissn
1673-5374issn
1876-7958pii
NeuralRegenRes_2022_17_2_283_317961journal_volume
17pub_type
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