Relation between urinary cytology abnormalities and cyclosporine A therapy in bone marrow transplant recipients.

Abstract:

:The aim of the study was to determine the relationship, if any, between abnormalities in urinary cytology and the administration of cyclosporine A in bone marrow transplant recipients. Specific attention was given to the presence of tubular cells with round inclusions (TCRI). Two bone marrow transplant recipient groups were studied: one with allogeneic bone marrow transplantation (BMT) (20 patients) who were treated with cyclosporine A, and the other with autologous BMT (12 patients) who did not receive cyclosporine A. Urinary cytology showed TCRI in 41.66% of the patients after autologous BMT and in 80% of the patients after allogeneic BMT. In the group of patients treated with allogeneic BMT, the occurrence of TCRI was associated with a high incidence of glycosuria and was followed by an increase in the blood level of cyclosporine A, an increase in the serum creatinine concentration and a decrease in the creatinine clearance. These results demonstrated that TCRI, although related to, were not found to be exclusively specific to the administration of cyclosporine A.

journal_name

Ren Fail

journal_title

Renal failure

authors

Sucic M,Boban D,Markovic-Glamocak M,Bogdanic V,Nemet D,Labar B,Cvoriscec D,Plavsic F,Stoos-Veic T,Mrsic M

doi

10.3109/08860229809045154

subject

Has Abstract

pub_date

1998-07-01 00:00:00

pages

613-20

issue

4

eissn

0886-022X

issn

1525-6049

journal_volume

20

pub_type

杂志文章
  • Leukocyte involvement in renal reperfusion-induced liver damage.

    abstract:BACKGROUNDS/AIMS:Renal ischemia-reperfusion (IR) induces organ damage in remote organs. The aim of this study was to assess the role of leukocytes in the induction of liver damage after renal IR injury. METHODS:Inbred mice were subjected to either sham operation or bilateral renal IR injury (60 min ischemia followed b...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2010.541585

    authors: Khastar H,Kadkhodaee M,Sadeghipour HR,Seifi B,Hadjati J,Delavari F,Soleimani M

    更新日期:2011-01-01 00:00:00

  • Influence of dialysis modality and membrane flux on quality of life in hemodialysis patients.

    abstract:BACKGROUND:The quality of life in patients undergoing hemodialysis is significantly disturbed. There are data that hemodiafiltration (HDF) may be more effective than conventional hemodialysis in the removal of uremic toxins and may reduce frequency and severity of intradialytic and postdialysis adverse symptoms in pati...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.684555

    authors: Knezevic MZ,Djordjevic VV,Radovanovic-Velickovic RM,Stankovic JJ,Cvetkovic TP,Djordjevic VM

    更新日期:2012-01-01 00:00:00

  • Association between MPO-463G > A polymorphism and chronic kidney disease: a meta-analysis.

    abstract:BACKGROUND/OBJECTIVE:Previous studies have shown that MPO -463G > A (rs2333227) might be associated with chronic kidney disease (CKD) susceptibility, but sample sizes of those studies are relatively small. Hence, we decided to perform a meta-analysis to evaluate the association. Methods/main results: Two investigators ...

    journal_title:Renal failure

    pub_type: 杂志文章,meta分析

    doi:10.1080/0886022X.2018.1499529

    authors: Qin J,Xing J,Li W,Zhang K,Wu Z

    更新日期:2018-11-01 00:00:00

  • Factors associated with hyperhomocysteinemia after renal transplantation.

    abstract::Recent studies show that clinically stable renal transplant recipients have an increased prevalence of hyperhomocysteinemia (hyperHcy), but the mechanism of this disorder has not yet been elucidated. The aim of the present study was to evaluate the factors associated with hyperHcy after a successful renal transplantat...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220500461260

    authors: Simić-Ogrizović S,Radivojević D,Radovic M,Lezaic V,Mirković D,Babić D,Dukanović L

    更新日期:2006-01-01 00:00:00

  • Can continuous intraperitoneal infusion of 125I-iothalamate and 131I-hippuran be used for measurement of GFR in conscious rats?

    abstract::We previously described a method to measure GFR in conscious spontaneously voiding rats. This method circumvents the need for anesthesia and for bladder instrumentation. It's main principle is the correction of renal 125I-iothalamate clearance for incomplete urine collection by the ratio of plasma and renal clearance ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229809045109

    authors: de Vries PA,Navis G,de Jong PE,de Zeeuw D

    更新日期:1998-03-01 00:00:00

  • Significant correlation between left ventricular systolic and diastolic dysfunction and decreased glomerular filtration rate.

    abstract::Cardiac dysfunction portends a poor prognosis in renal failure and vice versa. Functional abnormalities of heart in patients with renal insufficiency were frequently noted. The aim of this study is to assess the relationship between left ventricular systolic and diastolic function and renal function in patients with v...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.618792

    authors: Hsieh MC,Su HM,Wang SY,Tsai DH,Lin SD,Chen SC,Chen HC

    更新日期:2011-01-01 00:00:00

  • Hyperkalemia-induced accelerated idioventricular rhythm in a patient with acute renal failure.

    abstract::Electrolyte disorders can alter cardiac ionic currents and depending on the changes can promote proarrhythmic effects. Potassium (K(+)) is the most common intracellular cation related to arrhythmic disorders. Hyperkalemia is mainly seen in the setting of impaired renal function. Severe hyperkalemia may lead to rhythm ...

    journal_title:Renal failure

    pub_type: 信件

    doi:10.3109/0886022X.2011.653752

    authors: Gul EE,Erdogan HI,Yıldırım O,Soylu A,Nikus KC

    更新日期:2012-01-01 00:00:00

  • Salt sensitivity of blood pressure in non-dialysis patients with chronic kidney disease.

    abstract:BACKGROUND:Chronic kidney disease (CKD) is a world-wide public health problem. Hypertension is both a cause and a complication of CKD, and a risk factor for progression of kidney disease. The effect of salt intake on blood pressure (BP) and the salt sensitivity in non-dialysis patients with CKD were studied. METHODS:O...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.866008

    authors: Meng L,Fu B,Zhang T,Han Z,Yang M

    更新日期:2014-04-01 00:00:00

  • Hepatitis G virus infection in hemodialysis patients from urban Delhi.

    abstract::This study was designed to evaluate the seroprevalence of hepatitis G virus (HGV) infection, its impact, and its relationship with other hepatotropic viruses among chronic renal failure patients undergoing hemodialysis at the Lok Nayak Hospital, New Delhi. The study group consisted of 100 consecutive cases of patients...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:

    authors: Kumar D,Arora A,Singh NP,Kohli R,Kar P,Das BC

    更新日期:2005-01-01 00:00:00

  • Isolation, characterization, and evaluation of metallothionein in renal transplant patients.

    abstract::The plasma metallothionein concentration was studied in renal transplant patients. These patients are submitted to an attack of free radicals catalyzed by metals such as copper, zinc, cadmium, and others. The function of metallothionein is to bind toxic metals inhibiting the attack of free radicals and oxidative stres...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-120024287

    authors: Martín Mateo MC,Herreros C,Melero R,Bustamante J

    更新日期:2003-09-01 00:00:00

  • Regeneration of peritoneal mesothelium in a rat model of peritoneal fibrosis.

    abstract:BACKGROUND:Patients on long-term peritoneal dialysis develop progressive peritoneal fibrosis and loss of mesothelial layer. Regeneration of the mesothelium has been reported in the normal peritoneum but not the fibrotic peritoneum. Moreover, the origin of the regenerated mesothelial cells remains obscure. The aim of th...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220701741619

    authors: Nishioka Y,Miyazaki M,Abe K,Furusu A,Harada T,Ozono Y,Taguchi T,Koji T,Kohno S

    更新日期:2008-01-01 00:00:00

  • A prospective study of thromboelastography (TEG) and filter life during continuous veno-venous hemofiltration.

    abstract::Anticoagulants are commonly used to prolong circuit life during continuous hemofiltration. However, a clear correlation between routinely performed blood coagulability tests and circuit life has not been demonstrated. This lack of correlation may derive from the limited ability of such tests to describe the likelihood...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-100100873

    authors: Baldwin I,Tan HK,Bridge N,Bellomo R

    更新日期:2000-05-01 00:00:00

  • Assessment of matrix Gla protein, Klotho gene polymorphisms, and oxidative stress in chronic kidney disease.

    abstract::Increased vascular calcification and oxidative stress are considered as extra renal risk factors at the pathogenesis cardiovascular events in chronic kidney disease (CKD). We investigated matrix Gla protein (MGP) (T-138C, Glu60X, Thr83Ala) and Klotho (Cys370Ser) gene polymorphisms, serum MGP levels, and oxidative stre...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.605534

    authors: Karsli Ceppioğlu S,Yurdun T,Canbakan M

    更新日期:2011-01-01 00:00:00

  • Effects of pomegranate juice on hyperoxaluria-induced oxidative stress in the rat kidneys.

    abstract::To evaluate the role of the inducible nitric oxide synthase (iNOS), selective nuclear factor-kB (NF-kB), and p38-mitogene-activated protein kinase (p38-MAPK) on hyperoxaluria-induced oxidative stress and stone formation in rat kidneys. The rats were divided into five groups: group 1, control group; group 2: ethylene g...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220902963871

    authors: Ilbey YO,Ozbek E,Simsek A,Cekmen M,Somay A,Tasci AI

    更新日期:2009-01-01 00:00:00

  • Long-term online hemodiafiltration does not reduce the frequency and severity of acquired cystic kidney disease in hemodialysis patients.

    abstract:BACKGROUND:Acquired cystic kidney disease (ACKD) is a frequent complication in chronic hemodialysis (HD) patients and a risk factor for renal cell carcinoma. Online hemodiafiltration (HDF) provides better clearance of middle molecular weight solutes, but its effect on ACKD has not been investigated. MATERIALS AND METH...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220903003412

    authors: Weng CJ,Chang MY,Chen YC,Tian YC,Fang JT,Yang CW

    更新日期:2009-01-01 00:00:00

  • Familial Mediterranean fever and membranous glomerulonephritis: report of a case.

    abstract::Familial Mediterranean fever (FMF) is an autosomal recessive genetic disease characterized by recurrent attacks of fever and painful episodes of sterile polyserositis. Kidney involvement may occur as a result of secondary amyloidosis during the course of FMF. Previously, different types of glomerulopathies such as IgM...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860221003640090

    authors: Ceri M,Unverdi S,Altay M,Unverdi H,Ensari A,Duranay M

    更新日期:2010-01-01 00:00:00

  • The combination of sirolimus and cyclosporine does not delay initial renal graft function recovery.

    abstract:BACKGROUND:Sirolimus has been considered to be a non-nephrotoxic agent. It may delay graft function due to a potential hindrance of the recovery from acute tubular necrosis. It remains controversial as to whether the concomitant administration of sirolimus (SRL) with calcineurin inhibitors delays graft function in Asia...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220701860989

    authors: Hsu HJ,Tian YC,Chen YC,Lai BC,Fang JT,Yang CW,Wu MS

    更新日期:2008-01-01 00:00:00

  • Tubular cell HIV-1 gp120 expression induces caspase 8 activation and apoptosis.

    abstract::Renal biopsy data indicate that tubular epithelial cells serve as a reservoir for HIV-1 infection. We studied the effect of HIV-1 gp120 envelope gene expression on tubular cell apoptosis. HIV-1 gp120 was expressed in a lentiviral vector pHR-CMV-IRES2-EGFP-DeltaB. This plasmid construct was used to produce pseudotyped ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220902780101

    authors: Vashistha H,Husain M,Kumar D,Singhal PC

    更新日期:2009-01-01 00:00:00

  • Influenza vaccination in chronic hemodialysis patients. The effect of zinc supplementation.

    abstract::Since influenza increases the mortality of chronically ill patients we decided to study the effectiveness of influenza vaccination in hemodialysis (HD) patients. Nineteen HD patients aged from 20 to 60 years, on unrestricted diet and with no febrile episode, were studied. Blood samples were collected before the intram...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229209047668

    authors: Grekas D,Alivanis P,Kotzadamis N,Kiriazopoulou V,Pyrpasopoulos M,Tourkantonis A

    更新日期:1992-01-01 00:00:00

  • The significance of serum levels of soluble interleukin-2 receptor in patients undergoing maintenance hemodialysis.

    abstract::Background: Elevated serum levels of sIL-2R are commonly observed in patients undergoing maintenance hemodialysis (MHD). However, the clinical implications in these subjects are unclear. This study is aimed to assess the significance of elevated sIL-2R levels in MHD patients.Methods: A total of 382 MHD patients were f...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1761388

    authors: Chen X,Li Y,Ding X,Zou J,Shen B,Liu Z,Lv W,Cao X,Xiang F

    更新日期:2020-11-01 00:00:00

  • Normal mesenteric lymph ameliorates acute kidney injury following lipopolysaccharide challenge in mice.

    abstract:BACKGROUND:The kidney is one of the prior damaged organs subjected to severe infection and sepsis shock. Our previous studies have shown that the normal mesenteric lymph (NML) obtained from healthy dogs could alleviate multiple organ injuries following endotoxic shock. In the current study, we further investigated the ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2014.938585

    authors: Zhao ZG,Zhang LM,Song W,Du HB,Cui H,Niu CY

    更新日期:2014-09-01 00:00:00

  • Absence of interaction of diabetes mellitus with chronic kidney disease on mortality in acute heart failure.

    abstract:OBJECTIVES:To evaluate how chronic kidney disease (CKD) and diabetes mellitus (DM) influence in-hospital mortality in patients urgently admitted for acute heart failure (HF). METHODS:We used data from the Spanish "Minimum Basic Data Set" for 2006-2007 to evaluate clinical differences and crude mortality rates for pati...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2014.958974

    authors: de Miguel-Yanes JM,Méndez-Bailón M,Marco-Martínez J,Zapatero-Gaviria A,Barba-Martín R

    更新日期:2014-11-01 00:00:00

  • Low-dose IL-2 expands CD4+ regulatory T cells with a suppressive function in vitro via the STAT5-dependent pathway in patients with chronic kidney diseases.

    abstract:BACKGROUND:Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose IL-2 on CD4+ regulatory T cells expansion in vitro from patients with CKD. METHODS:A total of 148 newly di...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2018.1456462

    authors: Li Y,Liu X,Wang W,Wang S,Zhang J,Jiang S,Wang Y,Li L,Li J,Zhang Y,Huang H

    更新日期:2018-11-01 00:00:00

  • Acute renal failure due to acute rhabdomyolysis precipitated by MAST trousers and diflunisal.

    abstract::This report describes a patient who developed acute rhabdomyolysis and acute renal failure following the application of MAST trousers associated with an overdose of diflunisal. This association has not previously been reported. ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229309069415

    authors: Pilmore H,Walker RJ

    更新日期:1993-01-01 00:00:00

  • Trends and variations in intravenous vitamin D use among hemodialysis patients in the United States.

    abstract::Injectable vitamin D agents are commonly used to manage secondary hyperparathyroidism in dialysis patients. Yet, there are few data documenting the trends and geographic variations in the use of these agents in large, representative samples. We sought to describe patterns and variations in the use of vitamin D formula...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.734260

    authors: Beaubrun AC,Brookhart MA,Sleath B,Wang L,Kshirsagar AV

    更新日期:2013-01-01 00:00:00

  • Genomic distribution of 5-Hydroxymethylcytosine in mouse kidney and its relationship with gene expression.

    abstract::Ten-Eleven Translocation (TET) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytonsie (5hmC). Our recent work found a decline in global 5hmC level in mouse kidney insulted by ischemia reperfusion (IR). However, the genomic distribution of 5hmC in mouse kidney and its relationship with gene expression remai...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2016.1172973

    authors: Wang H,Huang N,Liu Y,Cang J,Xue Z

    更新日期:2016-07-01 00:00:00

  • Parathyroid hormone levels, calcium-channel blockers, and the dyslipidemia of nondiabetic hemodialysis patients.

    abstract:BACKGROUND:Experimental studies have shown that increased levels of parathyroid hormone (PTH) in uremia may cause elevation of intracellular calcium, predisposing to insulin resistance and lipid metabolism abnormalities. Administration of calcium-channel blockers (CCBs) in these models protects against the development ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:

    authors: Zanos S,Mitsopoulos E,Sakellariou G

    更新日期:2005-01-01 00:00:00

  • Protection of Tanshinone IIA to human peritoneal mesothelial cells (HPMC) through delaying cellular senescence induced by high glucose.

    abstract:BACKGROUND:Long-term peritoneal exposure to high glucose in the peritoneal dialysis (PD) solution may potentiate the development of peritoneal fibrosis in PD patients. The most important factor leading to peritoneal fibrosis may be injury of human peritoneal mesothelial cells (HPMC). Little is known about senescence of...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.623497

    authors: Cao D,Zhang M,Jiang C,Xue L,Sun C

    更新日期:2012-01-01 00:00:00

  • Ureteral anastomosis with a polyimide stent in rat kidney transplantation.

    abstract::Background: Complications associated with ureteral anastomosis in kidney transplantation are highly prevalent, despite the development of various types of stents. The current stent materials and placement methods have several limitations. This study attempts to provide an alternative by investigating ureteral anastomo...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1726386

    authors: Wang T,Yu Z,Chen C,Song Y,Zeng X,Su Y,Yi C

    更新日期:2020-11-01 00:00:00

  • Association of CYP3A variants with kidney transplant outcomes.

    abstract::Cyclosporine is used extensively in kidney transplantation and is a substrate for cytochrome P450 enzymes. The role of cytochrome p450 polymorphisms in kidney transplant outcome has not yet been fully elucidated. We investigate the clinical impact of single nucleotide polymorphisms in CYP3A4, CYP3A5, PPARα, and POR*28...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2015.1007013

    authors: Traynor C,Conlon P Jr,Phelan PJ,O'Kelly P,Elens L,McCormack M,Cavalleri G,Comber H,van Schaik RH,Conlon PJ

    更新日期:2015-05-01 00:00:00