Protection against experimental bubonic and pneumonic plague by a recombinant capsular F1-V antigen fusion protein vaccine.

abstract：:Human botulism is commonly associated with botulinum neurotoxin (BoNT) serotypes A, B, E and F. This suggests that the greatest need is for a tetravalent vaccine that provides protection against all four of these serotypes. In current study, we investigated the feasibility of generating several tetravalent vaccines th...

journal_title：Vaccine

authors： Yu YZ,Guo JP,An HJ,Zhang SM,Wang S,Yu WY,Sun ZW

更新日期：2013-05-07 00:00:00

abstract：BACKGROUND:Lifetime protection against pertussis has been adopted as a goal of immunization programs in Canada. To anticipate adult coverage with a combined product containing tetanus (T) and diphtheria (d) toxoids and acellular pertussis (aP) vaccine as a booster dose, we conducted a survey of households in British Co...

journal_title：Vaccine

authors： Skowronski DM,Pielak K,Remple VP,Halperin BA,Patrick DM,Naus M,McIntyre C

更新日期：2004-12-02 00:00:00

abstract：BACKGROUND:Persons with primary immunodeficiency disorders (PIDD) who receive oral poliovirus vaccine (OPV) or are household contacts of OPV recipients are at risk of excreting immunodeficiency-associated vaccine-derived polioviruses (iVDPVs). iVDPVs can be transmitted and cause paralytic polio. The objective of this s...

journal_title：Vaccine

authors： Sazzad HM,Rainey JJ,Mach O,Sutter R,Diordista S,Kawser CA,Mobarak R,Alam D,Chowdhury MA,Hossain MJ,Hasan AS,Luby SP

更新日期：2012-08-03 00:00:00

abstract：:The aim of the study was to analyze the impact of MenBvac, an outer membrane vesicle (OMV) vaccine against P1.7,16 strains, on meningococcal carriage. During a B:14:P1.7,16/ST-32 outbreak in Normandy (France), children aged 1-7 years were randomly selected to participate in the study. Among the 1082 volunteers, there ...

journal_title：Vaccine

authors： Delbos V,Lemée L,Bénichou J,Berthelot G,Deghmane AE,Leroy JP,Houivet E,Hong E,Taha MK,Caron F,B14 STOP study group.

更新日期：2013-09-13 00:00:00

abstract：:The aims of this study were to evaluate the impact of hepatitis B vaccination on the changing pattern of HBV infection in a former hyperendemic area (Afragola, South Italy), and to assess the long-term persistence of anti-HBs in two cohorts of individuals vaccinated as infants 18 and 23 years ago. Our data shows a sig...

journal_title：Vaccine

authors： Da Villa G,Romanò L,Sepe A,Iorio R,Paribello N,Zappa A,Zanetti AR

更新日期：2007-04-20 00:00:00

abstract：UNLABELLED:In low-income countries early measles vaccine (MV) is associated with reduced child mortality which cannot be explained by prevention of measles. A large thymus gland in infancy is also associated with reduced mortality. We hypothesized that early MV is associated with increased thymic size. Within a randomi...

journal_title：Vaccine

authors： Christensen LD,Eriksen HB,Biering-Sørensen S,Balé C,Do VA,Andersen A,Martins CL,Sodemann M,Aaby P,Benn CS

更新日期：2014-03-26 00:00:00

abstract：:Analysis of the anti-haemagglutinin serum antibody proteome from six H1N1pdm09 influenza A vaccinated subjects demonstrated restricted IgG1 heavy chain species encoded by IGHV5-51 and IGHV3-7 gene families in 2 subjects and either IGHV5-51 or IGHV3-7 in 4 individuals. All subjects exhibited a dominant IGKV3-20 light c...

journal_title：Vaccine

authors： Adamson PJ,Al Kindi MA,Wang JJ,Colella AD,Chataway TK,Petrovsky N,Gordon TP,Gordon DL

更新日期：2017-10-09 00:00:00

abstract：BACKGROUND:Pregnant women are at risk of severe influenza disease and are a priority group for influenza vaccination programs. Nicaragua expanded recommendations to include influenza vaccination to all pregnant women in the municipality of Managua in 2013. METHODS:We carried out a survey among 1,807 pregnant women who...

journal_title：Vaccine

authors： Arriola CS,Vasconez N,Thompson M,Mirza S,Moen AC,Bresee J,Talavera I,Ropero AM

更新日期：2016-02-17 00:00:00

abstract：BACKGROUND:Current national immunisation schedules differ between countries in terms of vaccine formulation, timing of vaccinations and immunisation programme funding and co-ordination. As a result, some HIV infected paediatric population may be left susceptible to vaccine preventable infections. Vaccines used in healt...

journal_title：Vaccine

authors： Bamford A,Manno EC,Mellado MJ,Spoulou V,Marques L,Scherpbier HJ,Niehues T,Oldakowska A,Rossi P,Palma P,PENTA-vac Group.

更新日期：2016-11-04 00:00:00

abstract：BACKGROUND:A key consideration for expanding recommendations for influenza vaccination is a robust assessment of immunogenicity and efficiency of transplacental antibody transfer after maternal vaccination. METHODS:We pooled data from two trials of maternal influenza vaccination to analyze vaccine immunogenicity with ...

journal_title：Vaccine

authors： Amin AB,Nunes MC,Tapia MD,Madhi SA,Cutland CL,Wairagkar N,Omer SB,for BMGF Supported Maternal Influenza Immunization Trials Investigators Group.

更新日期：2020-09-22 00:00:00

abstract：:To evaluate the safety and immunogenicity of a diphtheria, tetanus, acellular pertussis and Haemophilus infuenzae Type b (DTaP/Hib) combination vaccine first developed by a Chinese manufacturer, a randomized, two-stage, parallel controlled, single center clinical trial was conducted in Dafeng, Jiangsu Province of Chin...

journal_title：Vaccine

authors： Li G,Zhang H,Zhou W,Ye Q,Li F,Wang H,Hou Q,Xu Y,Ma X,Tan Y,Wang L,Li Y,Li H,Meng F,Liang Q,Liu A,Qin C,Wei W,Liu J,Ruan C,Tao W,Zhang S,Zheng H,Zhu F

更新日期：2010-06-07 00:00:00

abstract：:Activation of the innate immune system by different homotopes may direct the subsequent specific immune response, and as a consequence may have significant implications on vaccination. In this study, effects of i.v. administered lipopolysaccharide (LPS), and lipoteichoic acid (LTA), respectively, and s.c. administered...

journal_title：Vaccine

authors： Maldonado LM,Lammers A,Nieuwland MG,De Vries Reilingh G,Parmentier HK

更新日期：2005-04-15 00:00:00

abstract：:Fasciolosis continues to be a major cause of economic losses in the livestock industry and a growing threat to humans. The limited spectrum of effective anthelmintics and the appearance of resistances urge the need for developing an effective vaccine. Most studies have been focused on the use of TH1-polarizing adjuvan...

journal_title：Vaccine

authors： Orbegozo-Medina RA,Martínez-Sernández V,González-Warleta M,Castro-Hermida JA,Mezo M,Ubeira FM

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:In 2017, measles elimination was verified in Bhutan, and the country appears to have sufficiently high vaccination coverage to achieve rubella elimination. However, a measles and rubella serosurvey was conducted to find if any hidden immunity gaps existed that could threaten Bhutan's elimination status. MET...

journal_title：Vaccine

authors： Wangchuk S,Nogareda F,Tshering N,Khandu L,Pelden S,Wannemuehler K,Wangdi S,Wangchuk U,Mulders M,Tamang T,Patel MK

更新日期：2019-10-08 00:00:00

abstract：:Here, we evaluated the modulation of the immune response induced by Hsp90 of Nicotiana benthamiana (NbHsp90.3) against the Maltose Binding Protein (MBP) as a reporter antigen. Equimolar quantities of recombinant proteins were administered in mice as follows: MBP alone (MBP group), a mixture of MBP and rNbHsp90.3 (MBP+...

journal_title：Vaccine

authors： Corigliano MG,Fenoy I,Sander V,Maglioco A,Goldman A,Clemente M

更新日期：2013-12-02 00:00:00

abstract：INTRODUCTION:Immunization education for physicians-in-training is crucial to address vaccine concerns in clinical practice. Vaccine education is not standardized across residency programs. The Collaboration for Vaccination Education and Research (CoVER) team developed an online curriculum for pediatric (Peds) and famil...

journal_title：Vaccine

authors： Pahud B,Elizabeth Williams S,Lee BR,Lewis KO,Middleton DB,Clark S,Humiston SG

更新日期：2020-10-27 00:00:00

abstract：:We have recently developed a transmissible vaccine to immunize rabbits against myxomatosis and rabbit haemorrhagic disease based on a recombinant myxoma virus (MV) expressing the rabbit haemorrhagic disease virus (RHDV) capsid protein [Bárcena et al. Horizontal transmissible protection against myxomatosis and rabbit h...

journal_title：Vaccine

authors： Torres JM,Ramírez MA,Morales M,Bárcena J,Vázquez B,Espuña E,Pagès-Manté A,Sánchez-Vizcaíno JM

更新日期：2000-09-15 00:00:00

abstract：:The carboxyl-terminal region of the merozoite surface protein-1 (MSP1) is a leading candidate for a vaccine against malaria in the erythrocytic stage. In this study, we investigated the utility of interleukin-12 (IL-12) cDNA as an adjuvant for malaria DNA vaccine in a mouse challenge model. We found that co-immunizati...

journal_title：Vaccine

authors： Sakai T,Hisaeda H,Nakano Y,Zhang M,Takashima M,Ishii K,Maekawa Y,Matsumoto S,Nitta Y,Miyazaki Ji,Yamamoto S,Himeno K

更新日期：2003-03-28 00:00:00

abstract：BACKGROUND:In September 2011, the German Standing Committee on Vaccinations (STIKO) changed their recommendation regarding the mumps-measles-rubella-varicella vaccination (MMRV). We compared the immunization rates against MMRV in Germany before and after the STIKO intervention. METHODS:We recorded the immunization sta...

journal_title：Vaccine

authors： Sanftenberg L,Schrörs HJ,Schelling J

更新日期：2016-07-25 00:00:00

abstract：:The neuraminidase (NA) protein of influenza A viruses (IAV) has important functional roles in the viral replication cycle. Antibodies specific to NA can reduce viral replication and limit disease severity, but are not routinely measured. We analyzed NA inhibiting (NI) antibody titers in serum and respiratory specimens...

journal_title：Vaccine

authors： Sandbulte MR,Gauger PC,Kitikoon P,Chen H,Perez DR,Roth JA,Vincent AL

更新日期：2016-07-19 00:00:00

abstract：INTRODUCTION:Adolescents and young adults are at a high risk of developing human papillomavirus (HPV) infections, which can be prevented with the use of vaccines. Moreover, a combined immunization strategy for administration of HPV vaccines with other routine vaccines may lead to better compliance. We aim to comprehens...

journal_title：Vaccine

authors： Li Y,Zhu P,Wu M,Zhang Y,Li L

更新日期：2020-01-10 00:00:00

abstract：:This work describes the formulation design and development of a novel protein based adjuvant, a double mutant of heat labile toxin (dmLT), based on knowledge of the protein's structural integrity and physicochemical degradation pathways. Various classes of pharmaceutical excipients were screened for their stabilizing ...

journal_title：Vaccine

authors： Toprani VM,Sahni N,Hickey JM,Robertson GA,Middaugh CR,Joshi SB,Volkin DB

更新日期：2017-10-04 00:00:00

abstract：:To identify predictive factors of complete and age-appropriate vaccination status in Greece, we conducted a cross-sectional study, using stratified cluster sampling, among children attending the first year of the Greek Grammar school (about 6 years of age) and their parents/guardians. Almost 88% (N=3878) of pupils in ...

journal_title：Vaccine

authors： Danis K,Georgakopoulou T,Stavrou T,Laggas D,Panagiotopoulos T

更新日期：2010-02-17 00:00:00

abstract：:Rabies is one of the most lethal infectious diseases in the world, with a mortality approaching 100%. There are between 60,000 and 70,000 reported annual deaths, but this is probably an underestimation. Despite the fact that there are vaccines available for rabies, there is a real need of developing more efficacious a...

journal_title：Vaccine

authors： Fontana D,Kratje R,Etcheverrigaray M,Prieto C

更新日期：2015-08-20 00:00:00

abstract：:To prevent premature dismissal of promising vaccine programs, it is critical to determine if lack of efficacy in the field is due to allele specific-efficacy, rather than to the lack of immunogenicity of the candidate antigen. Here we use samples collected during a field trial of the AMA1-based FMP2.1/AS02A malaria va...

journal_title：Vaccine

authors： Ouattara A,Niangaly A,Adams M,Coulibaly D,Kone AK,Traore K,Laurens MB,Tolo Y,Kouriba B,Diallo DA,Doumbo OK,Plowe CV,Djimdé A,Thera MA,Laufer MK,Takala-Harrison S,Silva JC

更新日期：2020-07-31 00:00:00

abstract：:First year medical students at an allopathic medical school regional campus were asked to complete a 10-question survey at both the beginning and the conclusion of a required course on immunology, hematology and oncology. The survey was designed to solicit student attitudes about vaccination and the students' level of...

journal_title：Vaccine

authors： Onello E,Friedrichsen S,Krafts K,Simmons G Jr,Diebel K

更新日期：2020-01-22 00:00:00

abstract：:Seneca Valley virus (SVV) infection in pigs is associated with porcine idiopathic vesicular disease (PIVD). Outbreaks of SVV infection in pig herds have been reported in several Asia and Americas countries. Recently, a series of outbreaks of SVV infection occurred in China, Canada, Thailand and the United States. Howe...

journal_title：Vaccine

authors： Yang F,Zhu Z,Cao W,Liu H,Zhang K,Tian H,Liu X,Zheng H

更新日期：2018-02-01 00:00:00

abstract：:Protective mechanisms underlying the responses to mucosal vaccination are not yet clearly defined. Using the natural mouse pneumovirus pathogen, pneumonia virus of mice (PVM), we explore responses of wild type and interferon-gamma (IFNgamma) receptor gene-deleted mice to virulent challenge after mucosal vaccination wi...

journal_title：Vaccine

authors： Ellis JA,Martin BV,Waldner C,Dyer KD,Domachowske JB,Rosenberg HF

更新日期：2007-01-22 00:00:00

abstract：:Previous studies with the malaria vaccine RTS,S/AS02(A) in young children in a malaria endemic area of Mozambique have shown it to have a promising safety profile and to reduce the risk of Plasmodium falciparum infection and disease. In this study, we assessed the antibody responses to the P. falciparum and hepatitis ...

journal_title：Vaccine

authors： Aide P,Dobaño C,Sacarlal J,Aponte JJ,Mandomando I,Guinovart C,Bassat Q,Renom M,Puyol L,Macete E,Herreros E,Leach A,Dubois MC,Demoitie MA,Lievens M,Vekemans J,Loucq C,Ballou WR,Cohen J,Alonso PL

更新日期：2011-08-11 00:00:00

abstract：INTRODUCTION:Endemic measles persists in China, despite >95% reported coverage of two measles-containing vaccine doses and nationwide campaign that vaccinated more than 100 million children in 2010. In 2011, almost half of the 9943 measles cases in China occurred in children eligible for measles vaccination. We conduct...

journal_title：Vaccine

authors： Hao L,Ma C,Wannemuehler KA,Su Q,An Z,Cairns L,Quick L,Rodewald L,Liu Y,He H,Xu Q,Ma Y,Yu W,Zhang N,Li L,Wang N,Luo H,Wang H,Gregory CJ

更新日期：2016-12-12 00:00:00