Abstract:
:Ischemia/reperfusion injury (IRI) after free tissue transfer of the small intestine results in transmural tissue damage. This study examined the effects of IRI on the jejunum. Wistar rats served either as controls (N=10) or underwent clamping of the infrarenal aorta for 1 hour followed by 1 hour of reperfusion (N=10). Both ischemia and reperfusion reduced the protein and deoxyribonucleic acid content of the jejunal mucosa (p < 0.05). Myeloperoxidase activity in the jejunal mucosa remained relatively low. The expression of leukocyte function-associated antigen 1 and intercellular adhesion molecule 1 (ICAM-1) on the surface of mucosal cells was not altered significantly by the ischemic insult, but was reduced after the period of reperfusion (p < 0.05). This coincided with an increase in messenger ribonucleic acid (mRNA) for ICAM-1 within isolated mucosal cells (p < 0.05). The specific activity of glutaminase in isolated jejunal mucosal cells was diminished after ischemia and reperfusion (p < 0.05), and this was not associated with an appreciable change in glutaminase mRNA expression. These results have identified some molecular mechanisms underlying IRI of the small intestine that are possible candidates for therapeutic intervention.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Blennerhassett L,Kong SE,Heel K,McCauley R,Hall Jdoi
10.1097/00000637-199806000-00008subject
Has Abstractpub_date
1998-06-01 00:00:00pages
617-23issue
6eissn
0148-7043issn
1536-3708journal_volume
40pub_type
杂志文章abstract::This reconstructive microsurgery course will run yearly and was borne and popularized from its infant meeting the year before, primarily focused on perforator flaps. It is a 2-day course updating residents/registrars to attending physicians/consultants about the most topical advancements in microvascular reconstructiv...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000824
更新日期:2017-01-01 00:00:00
abstract::The medial circumflex femoral(GRACILIS) perforator free flap has been previously used to capture the superior medial thigh skin territory. This can also be valuable as a local flap, especially for adjacent groin wounds that are not uncommon after vascular interventions. Uncomplicated healing without vascular compromis...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.SAP.0000096149.92205.44
更新日期:2003-11-01 00:00:00
abstract::Simultaneous multiple free flaps have become a useful option in head and neck reconstructions. We performed a 10-year retrospective study between 2001 and 2010. There were 58 men and 1 woman. The overall mortality rate was 51.7%. The longest surviving patient is 9 years and 4 months, whereas the shortest surviving pat...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318274a49f
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:An increase in bariatric surgery has led to a rise in postbariatric contouring procedures. Despite a comprehensive preoperative assessment, body habitus in these patients may significantly limit the abdominal exam. Abdominal contouring procedures typically elevate large portions of the skin and fat off the abdo...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001546
更新日期:2018-11-01 00:00:00
abstract::The vascular anatomy of the dorsalis pedis-first dorsal metatarsal artery was investigated with regard to its general distribution and variation. We especially focused on the status of the dorsalis pedis-first dorsal metatarsal-first plantar metatarsal arterial interconnection and the sagittal course of the first dors...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199701000-00010
更新日期:1997-01-01 00:00:00
abstract::The reverse sural artery flap is frequently used for reconstruction of the distal third of the leg, ankle, and heel. The major disadvantage of the flap is compression of the pedicle within the subcutaneous tunnel and venous congestion. Others have cited a decrease in this problem by harvesting a midline cuff of gastro...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:2005-03-01 00:00:00
abstract::Microcirculatory changes were monitored in 20 deep inferior epigastric artery perforator (DIEAP) flaps during unilateral breast reconstruction until the seventh postoperative day using laser Doppler perfusion imaging. Measurements were recorded according to the zonal classification by Scheflan and Dinner. The cutaneou...
journal_title:Annals of plastic surgery
pub_type: 临床试验,杂志文章
doi:10.1097/SAP.0b013e3181f3e39b
更新日期:2011-08-01 00:00:00
abstract::A chronic ulcer of the posterior heel or lateral ankle can be a large problem for the patient. The lateral calcaneal artery flap is a reliable neurovascular local skin flap that can cover the defect after excision of the ulcer in this area. The flap includes the lateral calcaneal artery, sural nerve, and lesser saphen...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198812000-00007
更新日期:1988-12-01 00:00:00
abstract::Beckwith-Wiedemann syndrome (BWS) is a complex overgrowth disorder usually recognized at birth. Children diagnosed with BWS, particularly those with hemihypertrophy, experience an increased risk of developing benign and malignant tumors. This case report presents a 12-year-old girl with BWS and hemihypertrophy who rap...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/sap.0b013e3181b025f6
更新日期:2010-06-01 00:00:00
abstract::Intraosseous ganglia are occasionally found affecting the carpal bones of the hand and should be considered in the differential diagnosis of chronic wrist pain. They have characteristic radiographic findings of a cyst with a thin sclerotic rim. This case report illustrates an unusual presentation of a cyst in the luna...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200204000-00018
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Despite their widespread use, there are no evidence-based guidelines on the management of closed-suction drains or antibiotics in postmastectomy breast reconstruction. The purpose of this study was to assess consensus and variation in postoperative care among plastic surgeons. METHODS:The authors designed a...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31820c0593
更新日期:2011-05-01 00:00:00
abstract::Current recipient vessels for microvascular breast reconstruction include the internal mammary and the thoracodorsal systems. This review will focus on the advantages of the internal mammary artery and vein and reasons for their preference. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0b013e31821daac3
更新日期:2012-05-01 00:00:00
abstract::Transverse facial clefts (macrostomia) are rare disorders that result when the embryonic mandibular and maxillary processes of the first branchial arch fail to fuse properly to form the corners of the mouth. Macrostomia may be seen alone or in association with other anomalies. It may be unilateral, extending along a l...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181e6cfc1
更新日期:2011-04-01 00:00:00
abstract::During the past 10 years, there have been extensive developments in both "island" muscle and musculocutaneous flaps and in "free" microvascular transfers. Competition still exists between these two schools of surgical methodology, even though both methods are known to be complementary and have comparable success rates...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-198710000-00012
更新日期:1987-10-01 00:00:00
abstract::Forelimb buds of rat embryos at day 13 of gestation were cut and cultured in Dulbecco's modified Eagle medium. In the absence of serum, the epidermis did not cover the wound surface. In the presence of fetal calf serum or ultroser G, a serum substitute, epidermal wound closure appeared in a concentration-dependent man...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198912000-00002
更新日期:1989-12-01 00:00:00
abstract:BACKGROUND:International adoptees with cleft lip and palate (CLP) are a growing population in the United States. They represent a clinical challenge, presenting at various ages and stages of cleft repair. METHODS:A retrospective review of patients seen at the CLP Program at the Children's Hospital of Philadelphia (CHO...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000863
更新日期:2016-10-01 00:00:00
abstract::Full-thickness excision wounds infected with Staphylococcus hyicus, a pig pathogen, or Staphylococcus aureus, a human pathogen, were produced in pigs. The inoculated wounds were kept occluded for 2 days and then exposed and biopsied at intervals for 9 to 12 days. The exposed lesions were edematous and exudative. The S...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198909000-00004
更新日期:1989-09-01 00:00:00
abstract::Reconstruction of intraoral defects is one of the main aspects of head and neck cancer treatment. Since the advent of microvascular surgery in this field, free flap tissue transfer has become a common procedure, and various flaps have been described for soft tissue reconstruction. The lateral upper arm free flap is on...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001876
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Since its description in the 1970s, the radial forearm free flap has earned a clearly defined role in the armamentarium of reconstructive head and neck surgery. Three decades later, the donor site remains an intrinsic drawback primarily due to its esthetic impact, although functional morbidity is significant in...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000221622.41450.60
更新日期:2006-09-01 00:00:00
abstract:INTRODUCTION:The reconstruction of the postburn contracture area is always a challenge in the field of plastic surgery. Moreover, the joints are very sensitive to trauma and immobilization, showing a susceptibility to stiffness. The aim of this article is to emphasize the use of "Namaste flap"-modification of subcutane...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002076
更新日期:2019-12-01 00:00:00
abstract::We have developed a new in vivo model for the study of fetal wound healing. Fetal ICR mice (total gestation, 21 days) received a full-thickness incisional wound in the hind limb at gestational day 14 (N = 100). The wound was made with a 28.5-gauge needle that was passed transplacentally into the amniotic cavity. The w...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199710000-00008
更新日期:1997-10-01 00:00:00
abstract::The authors present their successful experience with an attractive alternative to the latissimus dorsi and gracilis muscle flaps for lower extremity reconstruction--the free rectus abdominis muscle flap. The muscle flap has a dual blood supply, but the longer pedicle length and larger vessel diameter of the inferior e...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198311000-00003
更新日期:1983-11-01 00:00:00
abstract::Infected wounds after total hip arthroplasty can be limb threatening. Management strategies are designed to eradicate infection, to obtain stable wound coverage, and to preserve the prosthesis. However, there is no general consensus for optimal management. The authors reviewed their 7-year combined orthopaedic and pla...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200212000-00006
更新日期:2002-12-01 00:00:00
abstract::We report the long-term use of tissue expanders for the reconstruction of a shoulder mound. Following a total forequarter amputation for the management of a fibrosarcoma, the patient continues to enjoy the benefits of a soft-tissue expander reconstruction eight years after its initial insertion. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199208000-00014
更新日期:1992-08-01 00:00:00
abstract::Children with metopic synostosis have a well-described clinical picture of trigonocephaly, often with hypotelorbitism. The craniofacial disorder itself is well recognized; however, objective prognostic factors for predicting the risk of reoperation are not well known. In 39 children with metopic synostosis, measuremen...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.SAP.0000058498.64113.11
更新日期:2003-08-01 00:00:00
abstract::According to most of the literature, sutures for microarterial repair must include the intima to prevent an "intimal flap" and occlusion of the anastomosis. Some authors have said that vessel diameter affects patency rate. This study was designed to evaluate these two statements. The femoral arteries (about 1.0 mm in ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197903000-00010
更新日期:1979-03-01 00:00:00
abstract::A simple, efficient, yet expedient method producing an ideal stent has proved to be highly reliable in over 150 clinical cases. When performed technically correctly, 100% graft take may be anticipated under most grafting circumstances. The method uses Reston (3-M Company, St. Paul, MN), a synthetic urethane foam pad, ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198407000-00005
更新日期:1984-07-01 00:00:00
abstract::Arterialized venous flaps are the result of the search for new flap techniques because conventional flaps are sometimes insufficient and have donor-site morbidity problems. In the patient presented here, a free arterialized venous flap measuring 12 x 8 cm was transferred from the forearm to a burn-scarred area on the ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199501000-00019
更新日期:1995-01-01 00:00:00
abstract::Local fascial flaps independently are a versatile option, reliable when properly designed, and technically simple to execute especially when compared to microsurgical tissue transfers. Although free flaps continue to be the method of choice to repair major distal extremity defects, for smaller wounds it could be prefe...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199704000-00014
更新日期:1997-04-01 00:00:00
abstract::Recurrent cicatricial entropion of the upper eyelid creates a surgical problem. We present a 53-year-old patient with complicated postsurgical fibrotic and scarred upper eyelid entropion. Double-opposed Z-plasty incisions were used at the anterior approach. The outer Z incision included the skin and the orbicularis oc...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199309000-00013
更新日期:1993-09-01 00:00:00