Abstract:
:The aim of this study was to investigate the relationship between history of selected diseases, genital traumas, and Peyronie's disease. A hospital-based case-control study was conducted at the Andrologic and Surgical Outpatient Units of the Policlinico Gemelli, Rome, where 134 men with Peyronie's disease and 134 male controls were interviewed. The association between Peyronie's disease and selected characteristics was estimated by means of odds ratios (OR) and 95% confidence intervals (CI). Patients who underwent invasive procedures on the penis (i.e., urethral catheterization, cystoscopy, and transurethral prostatectomy) had a 16-fold increased risk for Peyronie's disease (OR = 16.1, 95% CI: 1.8-142), while a nearly three-fold increase was observed among patients who had genital and/or perineal traumatisms (95% CI: 1.0-7.1). A history of urethritis, uricacidemia, and lipoma was also significantly associated with an increased risk for Peyronie's disease. Twenty-one percent of the cases and none of the controls were affected by Dupuytren's contracture, and 4% of cases and none of the controls reported familial history for Peyronie's disease. The frequency of inflammatory or fibromatous lesions of the genital tract of the partner was significantly higher in men with Peyronie's disease than among controls. These results were consistent when performing a stratified analysis according to the type of controls (i.e., controls affected by urologic or by digestive conditions) to rule out the potential effect of recall bias. The findings of the study lend support to clinical reports stressing the importance of genital traumatisms and genetic conditions in the development of Peyronie's disease.
journal_name
J Clin Epidemioljournal_title
Journal of clinical epidemiologyauthors
Carrieri MP,Serraino D,Palmiotto F,Nucci G,Sasso Fdoi
10.1016/s0895-4356(98)00015-8subject
Has Abstractpub_date
1998-06-01 00:00:00pages
511-5issue
6eissn
0895-4356issn
1878-5921pii
S0895435698000158journal_volume
51pub_type
杂志文章abstract:OBJECTIVE:To systematically review methodological articles which focus on nonpublication of studies and to describe methods of detecting and/or quantifying and/or adjusting for dissemination in meta-analyses. To evaluate whether the methods have been applied to an empirical data set for which one can be reasonably conf...
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更新日期:1999-02-01 00:00:00
abstract:OBJECTIVES:To solicit experiences with and perceptions of rapid reviews from stakeholders, including researchers, policy makers, industry, journal editors, and health care providers. STUDY DESIGN AND SETTING:An international survey of rapid review producers and modified Delphi. RESULTS:Forty rapid review producers re...
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journal_title:Journal of clinical epidemiology
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更新日期:2001-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1995-06-01 00:00:00
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doi:10.1016/j.jclinepi.2013.01.016
更新日期:2013-08-01 00:00:00
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doi:10.1016/j.jclinepi.2012.02.012
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