Discrepancy, coincidence or evidence in chronic idiopathic spastic paraparesis throughout the world. A meta-analysis on 2811 patients.

Abstract:

:HTLV-I has been associated with a chronic idiopathic spastic paraparesis (CHISPA) in man; however, a complete understanding of this association is still debated. We selected the most comprehensible papers on this topic between 1985 and 1996, and found that 1261 out of 2811 patients (44.9%) reported, throughout the world, were HTLV-I positive. The mean age was 39.5 years and there was a female predominance of 1.9:1. These results do not exclude the causality of HTLV-I as a germen associated to CHISPA; however, other causes (e.g., toxic, immunosuppressors) must be considered as participating in the multistep neurodegeneration observed in CHISPA throughout the world.

journal_name

Arq Neuropsiquiatr

authors

Leon-S FE,Costa CM,Gaffga N

doi

10.1590/s0004-282x1997000400002

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

530-5

issue

3B

eissn

0004-282X

issn

1678-4227

journal_volume

55

pub_type

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