Free circulating magnesium and renal magnesium handling during acute metabolic acidosis in humans.

abstract：BACKGROUND/AIMS:Patients with chronic renal failure (CRF) secondary to diabetes mellitus show a high incidence of atherosclerosis with its thrombotic complications. Both CRF and type 2 diabetes mellitus (DM2) results in fibrinolysis defects causally related to atherogenesis and thrombogenesis. It is not well known whet...

journal_title：American journal of nephrology

authors： Opatrný K Jr,Zemanová P,Mares J,Vít L,Opatrná S,Sefrna F,Hejda V,Tomsů M,Eiselt J,Massry SG

更新日期：2002-09-01 00:00:00

abstract：:This report reviews the features of 149 cases of renal allograft rupture, while adding a detailed description of 3 more cases to the English literature. From November, 1973 to November, 1979, 3 cases of renal allograft rupture occurred in 100 renal transplants performed at Research Medical Center, Kansas City, Mo., an...

journal_title：American journal of nephrology

authors： Thukral R,Mir AR,Jacobson MP

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is highly prevalent among patients on hemodialysis (HD) and is associated with poor prognosis. Treatment with interferon and ribavirin is poorly tolerated, and few data are available on the impact of new direct-acting antivirals (DAAs). This study was intended to analyze the...

journal_title：American journal of nephrology

authors： Abad S,Vega A,Hernández E,Mérida E,de Sequera P,Albalate M,Macías N,Milla M,López-Gómez JM

更新日期：2017-01-01 00:00:00

abstract：:A noninvasive method for the diagnosis of cardiac calcinosis, a life-threatening complication in hemodialysis patients with end-stage renal disease (ESRD), has not, as yet, been firmly established. We tested whether whole body scanning with 99m-technetium methylene diphosphonate (MDP) might visualize cardiac calcinosi...

journal_title：American journal of nephrology

authors： Eguchi M,Tsuchihashi K,Takizawa H,Nakahara N,Hagiwara M,Ohnishi H,Torii T,Hashimoto A,Marusaki S,Nakata T,Ura N,Shimamoto K

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND/AIMS:The value of neutrophil-gelatinase-associated lipocalin (NGAL), a novel biomarker in the detection of acute renal failure in children after cardiac surgery, has been highlighted in previous studies. The incidence of percutaneous coronary intervention (PCI) increases, which may possibly result in increas...

journal_title：American journal of nephrology

authors： Bachorzewska-Gajewska H,Malyszko J,Sitniewska E,Malyszko JS,Dobrzycki S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Aldosterone plays an important role in fibrosis. Recent studies showed that Na(+)-H(+) exchanger isoform 1 (NHE1) is involved in mineralocorticoid-induced organ fibrosis. In this study, we examined the role of NHE1 in aldosterone-induced fibronectin accumulation in rat mesangial cells and the signaling pathw...

journal_title：American journal of nephrology

authors： Zhang M,Chen J,Lai L,You L,Lin S,Hao C,Gu Y

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Hyperkalemia is common in patients receiving maintenance hemodialysis. However, few studies have examined the association between serum potassium level and mortality. METHODS:This study used annual cohorts of hemodialysis patients during 2007-2010. To determine hyperkalemia prevalence, monthly hyperkalemia ...

journal_title：American journal of nephrology

authors： Yusuf AA,Hu Y,Singh B,Menoyo JA,Wetmore JB

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Gastrointestinal (GI) symptoms in renal transplant recipients may be caused due to mycophenolic acid (MPA) toxicity. Using small bowel capsule endoscopy (SBCE) we examined the impact of conversion from Mycophenolate Mofetil (MMF) to enteric-coated formulation of Mycophenolate Sodium (EC-MPS) given to tr...

journal_title：American journal of nephrology

authors： Bunnapradist S,Sampaio MS,Wilkinson AH,Pham PT,Huang E,Kuo HT,Anastasi B,Danovitch GM,Lo SK

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Serum creatinine (SCr) levels are decreased following traumatic amputation, leading to the overestimation of glomerular filtration rate (GFR). β-Trace protein (BTP) and β2-microglobulin (B2M) strongly correlate with measured GFR and have not been studied following amputation. We hypothesized that BTP and B2M...

journal_title：American journal of nephrology

authors： Little DJ,Yuan CM,Thurlow JS,Gounden V,Doi SQ,Pruziner A,Abbott KC,Theeler BJ,Olson SW

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:There is a higher risk of gastrointestinal (GI) bleeding in patients treated with dabigatran versus warfarin. We analyzed the impact of renal function on the relative risk of bleeding in patients converted to dabigatran. METHODS:Patients aged ≥65 years who received anticoagulation with warfarin for a minimu...

journal_title：American journal of nephrology

authors： Kalil RS,Kaboli PJ,Liu X,Vaughan-Sarrazin M

更新日期：2016-01-01 00:00:00

abstract：UNLABELLED:Although it is anticipated that most patients with renal insufficiency will progress towards end-stage renal disease (ESRD) there have been few population-based studies to validate this assumption. We examined serial creatinines from 3,874 anonymous patients at an urban VA medical center who had a baseline c...

journal_title：American journal of nephrology

authors： Fink JC,Salmanullah M,Blahut SA,Weir MR,Sawyer R,Henrich WL,Hise MK

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Transglutaminase 2 (TGM2) is a calcium-dependent enzyme that can cross-link nearly all extracellular matrix (ECM) proteins and can facilitate cell-ECM interaction through integrins. Given the importance of the ECM in vascular calcification we tested the hypothesis that increased TGM2 activity may accelerate ...

journal_title：American journal of nephrology

authors： Chen NX,O'Neill K,Chen X,Kiattisunthorn K,Gattone VH,Moe SM

更新日期：2013-01-01 00:00:00

abstract：:Fifty-four patients with noninsulin-dependent diabetes mellitus, who had established nephropathy, were examined to evaluate the risk factors for the progression of diabetic nephropathy. Time-averaged values of blood pressure, serum total cholesterol and fasting plasma glucose concentrations, and the degree of proteinu...

journal_title：American journal of nephrology

authors： Yokota C,Kimura G,Inenaga T,Kawano Y,Matsuoka H,Omae T

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Vascular calcification is seen in most patients on dialysis and is strongly associated with cardiovascular mortality. Vascular calcification is promoted by phosphate, which generally reaches higher levels in hemodialysis than in peritoneal dialysis. However, whether vascular calcification develops less in pe...

journal_title：American journal of nephrology

authors： Jansz TT,van Reekum FE,Özyilmaz A,de Jong PA,Boereboom FTJ,Hoekstra T,Verhaar MC,van Jaarsveld BC

更新日期：2018-01-01 00:00:00

abstract：:45 bone biopsies from patients with chronic uremia were reviewed to define which noninvasive investigations were of value in predicting the histological diagnosis and to quantify the spectrum of uremic bone disease at a center that has consistently used an aluminum-free dialysis bath. 17 biopsies were taken postmortem...

journal_title：American journal of nephrology

authors： Heaf JG,Joffe P,Pødenphant J,Andersen JR

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Interest in nephrology careers is declining, possibly due to perceptions of the field and/or training aspects. Understanding practices of medical schools successfully instilling nephrology interest could inform efforts to attract leading candidates to the specialty. METHODS:The American Society of Nephrolog...

journal_title：American journal of nephrology

authors： Sozio SM,Pivert KA,Shah HH,Chakkera HA,Asmar AR,Varma MR,Morrow BD,Patel AB,Leight K,Parker MG

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Growth hormone (GH) resistance in CKD is partly due to increased expression of SOCS2, a GH signaling negative regulator. In SOCS2 absence, body growth is exaggerated. However, GH overexpression in mice causes glomerulosclerosis. Accordingly, we tested whether lack of SOCS2 improves body growth, but accelerat...

journal_title：American journal of nephrology

authors： Landau D,Assadi MH,Abu Hilal R,Chen Y,Rabkin R,Segev Y

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Uric acid has been reported to be a risk factor for the development of chronic kidney disease; however, no study has examined whether uric acid may confer a risk for acute kidney injury. METHODS:We investigated the relation between serum uric acid and the incidence of postoperative acute kidney injury in pa...

journal_title：American journal of nephrology

authors： Ejaz AA,Beaver TM,Shimada M,Sood P,Lingegowda V,Schold JD,Kim T,Johnson RJ

更新日期：2009-01-01 00:00:00

abstract：:A comparative clinicopathological study was retrospectively performed in 61 children and 51 adults with IgA nephropathy. Hematuria and/or proteinuria as a chance finding was the most common initial clinical sign, being observed in 82.0% of the children and in 52.9% of the adults. At renal biopsy, hypertension and seve...

journal_title：American journal of nephrology

authors： Okada K,Funai M,Kawakami K,Kagami S,Yano I,Kuroda Y

更新日期：1990-01-01 00:00:00

abstract：:Bardoxolone methyl has been reported to cause detrimental cardiovascular events in the terminated BEACON Phase III human clinical trial via modulation of the renal endothelin pathway. However, the effects of bardoxolone methyl administration on the endothelin pathway in the heart are unknown. Our purpose in this persp...

journal_title：American journal of nephrology

authors： Camer D,Huang XF

更新日期：2014-01-01 00:00:00

abstract：:Bicarbonate dialysate is claimed to be superior to acetate for both chronic and acute hemodialysis. We compared acetate and bicarbonate dialysates in 30 acute renal failure patients during 120 dialyses. 4 patients were diabetic and 2 had liver failure. Patients were dialyzed alternating acetate and bicarbonate dialysa...

journal_title：American journal of nephrology

authors： Borges HF,Fryd DS,Rosa AA,Kjellstrand CM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Fibrillary glomerulonephritis is characterized by randomly arranged fibrils, approximately 20 nm in diameter by electron microscopy. Patients present with proteinuria, hematuria and kidney insufficiency, and about half of the reported patients progress to end-stage kidney disease within 4 years. The dependen...

journal_title：American journal of nephrology

authors： Payan Schober F,Jobson MA,Poulton CJ,Singh HK,Nickeleit V,Falk RJ,Jennette JC,Nachman PH,Pendergraft Iii WF

更新日期：2017-01-01 00:00:00

abstract：:A variety of histologic changes have been observed in the kidneys of patients with light-chain deposition disease. We report 3 cases with kappa light chain deposition who presented with diverse clinical, histological, and ultrastructural features. All the cases were diagnosed by the presence of monoclonal kappa light ...

journal_title：American journal of nephrology

authors： Venkataseshan VS,Faraggiana T,Hughson MD,Buchwald D,Olesnicky L,Goldstein MH

更新日期：1988-01-01 00:00:00

abstract：:Forty-eight chronic hemodialysis patients were divided comparably into two groups (24 patients in each). Two micrograms of 1 alpha(OH)D3 was administered to one group for 3 months and its placebo to the other group. In the 1 alpha(OH)D3-treated group, serum total calcium increased from 7.82 +/- 0.11 (mean +/- SEM) to ...

journal_title：American journal of nephrology

authors： Shimamatsu K,Onoyama K,Fujimi S,Iseki K,Fujishima M

更新日期：1988-01-01 00:00:00

abstract：:To define the incidence of non-A, non-B (NANB) hepatitis and evaluate possible risk factors, we reviewed records of 163 patients on chronic dialysis during a 3-year period. 23 cases of NANB hepatitis occurred, 13 (27%) in 49 center dialysis, 8 (10%) in 77 home hemodialysis (p less than 0.02) and 2 (5%) in 37 peritonea...

journal_title：American journal of nephrology

authors： Seaworth BJ,Garrett LE,Stead WW,Hamilton JD

更新日期：1984-01-01 00:00:00

abstract：:To evaluate the significance of tubulointerstitial lesions in the cortical area of renal biopsy specimens, clinicopathological studies were performed on 101 cases of IgA nephropathy, 31 cases of IgA-negative (non-IgA) proliferative glomerulonephritis and 75 cases of idiopathic membranous glomerulonephritis. The degree...

journal_title：American journal of nephrology

authors： Abe S,Amagasaki Y,Iyori S,Konishi K,Kato E,Sakaguchi H

更新日期：1989-01-01 00:00:00

abstract：:The review focuses on biochemical metabolisms of conventional buffers and emphasizes advantages of sodium pyruvate (Pyr) in the correction of intracellular acidosis. Exogenous lactate (Lac) as an alternative of natural buffer, bicarbonate, consumes intracellular protons on an equimolar basis, regenerating bicarbonate ...

journal_title：American journal of nephrology

authors： Zhou FQ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:Serum phosphorus levels have been associated with adverse long-term outcome in several populations, however, no prior studies evaluated short-term postoperative outcome. The present study evaluated the predictive value of phosphorus levels on 30-day outcome after vascular surgery. METHODS:The study inc...

journal_title：American journal of nephrology

authors： van Kuijk JP,Flu WJ,Chonchol M,Valentijn TM,Verhagen HJ,Bax JJ,Poldermans D

更新日期：2010-01-01 00:00:00

abstract：:The effects of cisplatin (5 mg/kg BW given intraperitoneally) on renal concentration mechanism were evaluated initially by clearance studies in rats 5-7 days after cisplatin administration and compared to normal rats. During hypotonic saline infusion, cisplatin rats showed a lower inulin clearance (0.56 +/- 0.07 vs. 1...

journal_title：American journal of nephrology

authors： Seguro AC,Shimizu MH,Kudo LH,dos Santos Rocha A

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Nephrology research is expanding, and harnessing the much-needed information and data for the practice of evidence-based medicine is becoming more challenging. In this study, we used the natural language processing and text mining approach to mitigate some of these challenges. METHODS:We analyzed 17,412 abs...

journal_title：American journal of nephrology

authors： Zengul FD,Lee T,Delen D,Almehmi A,Ivankova NV,Mehta T,Topuz K

更新日期：2020-01-01 00:00:00