The role of tacrolimus in adult kidney transplantation: a review.

abstract：:Chronic allograft nephropathy (CAN) is a major problem after renal transplantation and chronic inflammation can be one of its promoters. C-reactive protein (CRP) is an important marker of inflammation and atherosclerosis. We retrospectively analyzed the predictive role of serum CRP levels on the development of CAN and...

journal_title：Clinical transplantation

authors： Sezer S,Akcay A,Ozdemir FN,Kulah E,Arat Z,Haberal M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Patients on organ transplant waiting lists continue to far exceed donor rates. We seek to understand the barriers preventing people in a Canadian city from donating organs for transplantation. METHODS:One thousand adults were surveyed assessing knowledge, personal involvement, and attitudes about organ dona...

journal_title：Clinical transplantation

authors： Lee E,Midodizi W,Gourishankar S

更新日期：2010-11-01 00:00:00

abstract：:In view of the scarcity of organ resources available for transplantation, living donor liver transplantation (LDLT) is gaining growing importance in the treatment of chronically terminal liver diseases. In the period between December 1999 and October 2000, 47 potential living liver donors were evaluated and 24 right h...

journal_title：Clinical transplantation

authors： Walter M,Bronner E,Pascher A,Steinmüller T,Neuhaus P,Klapp BF,Danzer G

更新日期：2002-10-01 00:00:00

abstract：:Adverse symptoms of immunosuppressants (ASI) impact quality of life (QOL) in solid organ transplant recipients; however, standardized approaches for active ASI surveillance and intervention are lacking. While management is highly clinician dependent, clinician views remain largely unexplored. We surveyed Canadian Soci...

journal_title：Clinical transplantation

authors： Harrison JJ,Mansell H,Blydt-Hansen T

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:Conversion from calcineurin inhibitor (CI)-based maintenance immunosuppression to sirolimus (SRL)-based immunosuppression may be beneficial in selected renal transplant recipients. The purpose of this study was to evaluate the safety and efficacy of a daclizumab (DAC) bridge protocol in patients converted ...

journal_title：Clinical transplantation

authors： Sundberg AK,Rohr MS,Hartmann EL,Adams PL,Stratta RJ

更新日期：2004-01-01 00:00:00

abstract：:The frequent scarcity of organ donors has made it necessary to consider transplantation of organs that may have the potential to transmit hepatitis B virus (HBV) to the recipient. Previous reports have documented the probability of infection of particular recipient populations with transplanted livers from hepatitis B...

journal_title：Clinical transplantation

authors： Dodson SF

更新日期：2000-01-01 00:00:00

abstract：AIMS:To evaluate the effect of donor liver resident mesenchymal cells, M2 macrophages on liver graft outcome after living donor liver transplantation. MATERIALS AND METHODS:Seventy donor biopsies were included in the study. Outcomes at day 3, 7, 30, and 180 postliver transplantation were assessed. Mesenchymal stem cel...

journal_title：Clinical transplantation

authors： Nigam N,Bihari C,Lal D,Rastogi A,Kumar S,Pamecha V,Kaur S,Kumar A,Sarin SK

更新日期：2018-03-01 00:00:00

abstract：:The number of nonrenal solid-organ transplants increased substantially in the last few decades. Many of these patients develop renal failure and receive kidney transplantation. The aim of this study was to evaluate patient and kidney allograft survival in primary, repeat, and kidney-after-nonrenal organ transplantatio...

journal_title：Clinical transplantation

authors： El-Husseini A,Aghil A,Ramirez J,Sawaya B,Rajagopalan N,Baz M,Mei X,Davenport DL,Gedaly R

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:We examined the risk of adverse pregnancy outcomes in primiparous kidney donors compared to matched controls. METHODS:Fifty-nine women with a history of kidney donation prior to their first pregnancy with normal renal function and no history of kidney disease, diabetes or chronic hypertension were matched 1...

journal_title：Clinical transplantation

authors： Davis S,Dylewski J,Shah PB,Holmen J,You Z,Chonchol M,Kendrick J

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:One severe side effect of calcineurin inhibitors (CNIs: such as cyclosporine [CsA] and tacrolimus [FK506]) is neurotoxicity. CNIs are substrates for CYP3A5 and P-glycoprotein (P-gp), encoded by ABCB1 gene. In the present study, we hypothesized that genetic variability in CYP3A5 and ABCB1 genes may be associa...

journal_title：Clinical transplantation

authors： Yanagimachi M,Naruto T,Tanoshima R,Kato H,Yokosuka T,Kajiwara R,Fujii H,Tanaka F,Goto H,Yagihashi T,Kosaki K,Yokota S

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:A long-term prospective randomized trial evaluating alemtuzumab, a humanized anti-CD52 monoclonal antibody, in a predominantly non-Caucasian population has yet to be reported. METHODS:Ninety deceased donor (DD) first renal transplant recipients were randomized into three different antibody induction group...

journal_title：Clinical transplantation

authors： Ciancio G,Burke GW,Gaynor JJ,Roth D,Kupin W,Rosen A,Cordovilla T,Tueros L,Herrada E,Miller J

更新日期：2008-03-01 00:00:00

abstract：:Endothelium-dependent vasodilation in the peripheral circulation may be impaired in heart transplant recipients (HTx rec). Conflicting results have been obtained and the mechanisms involved have not been examined. In the present study, we examined whether long-time survivors of heart transplantation (Tx) show signs of...

journal_title：Clinical transplantation

authors： Holm T,Aukrust P,Andreassen AK,Ueland T,Brosstad F,Frøland SS,Simonsen S,Gullestad L

更新日期：2000-06-01 00:00:00

abstract：:This study investigated the association between religious beliefs and opinions on xenotransplantation among students from three different countries. A lower proportion of religious students accepted xenotransplantation than did non-religious students. A higher proportion of Protestant students seemed to accept xenotra...

journal_title：Clinical transplantation

authors： Hagelin J,Hau J,Schapiro SJ,Suleman MA,Carlsson HE

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:The proportion of prospective living donors disqualified for medical reasons is unknown. The objective of this study is to delineate and quantify specific reasons for exclusion of prospective living donors from kidney donation. METHODS:All adult prospective kidney donors who contacted our transplant program...

journal_title：Clinical transplantation

authors： Lapasia JB,Kong SY,Busque S,Scandling JD,Chertow GM,Tan JC

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:There are little data on the pre- and post-liver transplantation (LT) outcomes of patients having autoimmune hepatitis-primary biliary cholangitis (AIH-PBC), AIH-primary sclerosing cholangitis (AIH-PSC), and AIH-small-duct PSC (AIH-SDPSC). The aim of this study was to analyze pre- and post-LT outcomes and su...

journal_title：Clinical transplantation

authors： Chayanupatkul M,Fiel MI,Schiano TD

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:There is a severe shortage of organs for transplantation worldwide, and Mexico has one of the lowest organ donation rates. In this study, we explored the psychosocial barriers that prevent posthumous organ donation by Mexicans. METHOD:We asked 218 adults who were not willing to be donors to complete the s...

journal_title：Clinical transplantation

authors： Marván ML,Álvarez Del Río A,Jasso K,Santillán-Doherty P

更新日期：2017-11-01 00:00:00

abstract：:Cardiac allograft rejection and failure may require mechanical circulatory support as bridge-to-retransplantation. Prognosis in this patient group is poor and implantable ventricular assist devices have had limited success due to organ failure associated with the high dose immunosuppression required to treat ongoing r...

journal_title：Clinical transplantation

authors： Kalya A,Jaroszewski D,Pajaro O,Scott R,Gopalan R,Kasper D,Arabia F

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Cyclosporine (CsA) and tacrolimus (Tac) in heart transplantation (HTx) have been compared but with certain drawbacks. We compared both drugs in a prospective analysis with medium-term follow-up. METHODS:Hundred and six patients were randomized to receive CsA or Tac (53 per group). Target levels of CsA were ...

journal_title：Clinical transplantation

authors： Sánchez-Lázaro IJ,Almenar L,Martínez-Dolz L,Buendía-Fuentes F,Agüero J,Navarro-Manchón J,Vicente JL,Salvador A

更新日期：2011-07-01 00:00:00

abstract：:Whole pancreas and islet cell transplantation are both reliant upon the procurement and preservation of a high quality donor pancreas for a successful outcome. In the climate of a reducing donor pool it is imperative that donor optimization, meticulous surgical retrieval and evidence based methods of preservation are ...

journal_title：Clinical transplantation

authors： Ridgway D,Manas D,Shaw J,White S

更新日期：2010-01-01 00:00:00

abstract：:Temporary graft dysfunction with gas exchange abnormalities is a common finding during the postoperative course of a lung transplant and is often determined by the post-reimplantation syndrome. Supportive measures including oxygen by mask, inotropes, diuretics, and pulmonary vasodilators are usually effective in non-s...

journal_title：Clinical transplantation

authors： Feltracco P,Serra E,Barbieri S,Persona P,Rea F,Loy M,Ori C

更新日期：2009-09-01 00:00:00

abstract：:Pancreas retransplantation has become more frequent and represents a technical challenge for surgeons. Knowledge of alternative surgical options could be useful in difficult cases. We present a case of brutal diabetes mellitus in a patient with severe vascular disease that underwent a third pancreas transplant. Diffic...

journal_title：Clinical transplantation

authors： Garcia-Roca R,Humar A,Sturdevant M,Kobayashi T,Dunn T,Kandaswamy R,Sutherland D

更新日期：2010-05-01 00:00:00

abstract：:A total of 123 consecutive patients with advanced-stage, acute leukemia undergoing HSCT from HLA-identical sibling donors were analyzed. A G-CSF-primed DLI was planned within day 60 post-transplantation before hematologic relapse was diagnosed. Fifty of the 123 individuals received prophylactic DLI, and 73 individuals...

journal_title：Clinical transplantation

authors： Wang Y,Liu DH,Fan ZP,Sun J,Wu XJ,Ma X,Xu LP,Liu KY,Liu QF,Wu DP,Huang XJ

更新日期：2012-07-01 00:00:00

abstract：:Calcineurin inhibitors (CNI) have been commonly used as pivotal immunosuppressive agents to renal transplant recipients and have contributed significantly to improving short-term allograft survival. However, long-term administration of CNI may cause an adverse effect on kidney function, known as chronic nephrotoxicity...

journal_title：Clinical transplantation

authors： Horike K,Takeda A,Yamaguchi Y,Ogiyama Y,Yamauchi Y,Murata M,Kawaguchi T,Suzuki T,Otsuka Y,Inaguma D,Goto N,Watarai Y,Uchida K,Morozumi K

更新日期：2011-07-01 00:00:00

abstract：:Endothelial dysfunction is of vital importance, as it may cause ischemia and dysfunction in various organs. Despite, this problem has been well documented in patients with end-stage renal disease (ESRD), there is not enough data considering this issue following renal transplantation. One of the potential causes of end...

journal_title：Clinical transplantation

authors： Oflaz H,Turkmen A,Kazancioglu R,Kayacan SM,Bunyak B,Genchallac H,Erol B,Mercanoglu F,Umman S,Sever MS

更新日期：2003-06-01 00:00:00

abstract：:The organ shortage is one of the major challenges in the field of organ transplantation, yet the percentage of kidneys procured and discarded prior to transplantation has continued to rise to twenty percent. The causes of organ discard are complex, yet an urgent need exists for collaborative efforts to maximize the ut...

journal_title：Clinical transplantation

authors： Cooper M,Formica R,Friedewald J,Hirose R,O'Connor K,Mohan S,Schold J,Axelrod D,Pastan S

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:We examined the effect of haemodialysis (HD) or peritoneal dialysis (PD) on acute rejection, delayed graft function (DGF), graft and patient survival after cadaveric renal transplantation. MATERIALS AND METHODS:We carried out a retrospective analysis of 325 patients (cyclosporin [CyA]-based therapy) who h...

journal_title：Clinical transplantation

authors： Joseph JT,Jindal RM

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Liver ischaemia-reperfusion (I/R) occurs during resuscitation from haemorrhagic shock, hepatic transplantation and anatomic resection of the liver. This injury is associated with hepatocellular enzyme release and hepatocyte necrosis. The impact of chronic illnesses such as diabetes mellitus (DM) on hepatic I...

journal_title：Clinical transplantation

authors： Rogers H 3rd,Zibari GB,Roberts J,Turnage R,Lefer DJ

更新日期：2004-01-01 00:00:00

abstract：:The aim of this study was to evaluate pancreatic function in total parenteral nutrition (TPN)-dependent children with permanent intestinal failure by measuring immunoreactive trypsinogen (IRT) levels. Between 1992 and 1996, 105 pediatric patients with permanent intestinal failure were referred to the Children's Hospit...

journal_title：Clinical transplantation

authors： Rovera GM,Sigurdsson L,Reyes J,Bouch LD,Naylor EW,Kocoshis SA

更新日期：1999-10-01 00:00:00

abstract：:With increasing shortage of donor organs and changes in organ allocation systems, there is a considerable need for alternative or supportive techniques in the field of liver transplantation. Liver cell transplantation (LCT) is such an innovative technique that is especially promising for use in children, because it is...

journal_title：Clinical transplantation

authors： Meyburg J,Schmidt J,Hoffmann GF

更新日期：2009-12-01 00:00:00

abstract：:Although the kidney transplant program at this center has been active for the past 18 yr, five out of the seven cases of post-transplant lymphoma in kidney transplant patients were observed over the past 2 yr. During this period, we have shifted from cyclosporine to tacrolimus (FK506 or prograf) for maintenance immuno...

journal_title：Clinical transplantation

authors： Ciancio G,Siquijor AP,Burke GW,Roth D,Cirocco R,Esquenazi V,Byrne GE Jr,Miller J

更新日期：1997-06-01 00:00:00