Gender gap in aortic cholesterol accumulation in cholesterol-clamped rabbits: role of the endothelium and mononuclear-endothelial cell interaction.

abstract：BACKGROUND:Short-term hibernating myocardium is characterized by a decrease in contractile function in proportion to the reduced myocardial blood flow. Myocardial creatine phosphate content, initially decreased during the first minutes of ischemia, returns to near-control values, the ischemia-induced net lactate produc...

journal_title：Circulation

authors： Schulz R,Rose J,Martin C,Brodde OE,Heusch G

更新日期：1993-08-01 00:00:00

abstract：:The clinical use of citrate-phosphate-dextrose during blood-product transfusion is known to affect ionized calcium levels and can result in depression of myocardial contractility. The immature heart appears to have an intrinsic reduction in contractile state compared with the adult heart and may be more dependent on t...

journal_title：Circulation

authors： Rebeyka IM,Yeh T Jr,Hanan SA,Borges MR,Lee KF,Tuchy GE,Abd-Elfattah AS,Wechsler AS

更新日期：1990-11-01 00:00:00

abstract：:Under the auspices of the Agency for Healthcare Research and Quality, the United States Preventive Services Task Force (USPSTF) recently released an update to its 1996 Peripheral Arterial Disease (PAD) Screening Recommendation Statement. The USPSTF recommended against PAD screening, giving the practice a "D" level rec...

journal_title：Circulation

authors： Beckman JA,Jaff MR,Creager MA

更新日期：2006-08-22 00:00:00

abstract：:Global ventricular function was evaluated by both multiple gated cardiac blood pool scans (MUGA) and contrast ventriculograms in a group of 17 patients with suspected coronary artery disease. The contrast ventriculograms were analyzed frame by frame to generate a volume versus time curve for each patient, while the tr...

journal_title：Circulation

authors： Burow RD,Strauss HW,Singleton R,Pond M,Rehn T,Bailey IK,Griffith LC,Nickoloff E,Pitt B

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease is the major cause of death in older women. Information on the relation of menopause and hormone replacement therapy with carotid atherosclerosis is limited. METHODS AND RESULTS:We examined cross-sectionally the association of menopausal status, years since last menstruation, and horm...

journal_title：Circulation

authors： Nabulsi AA,Folsom AR,Szklo M,White A,Higgins M,Heiss G

更新日期：1996-10-15 00:00:00

abstract：BACKGROUND:The synthetic catecholamine dobutamine increases stroke volume in normal subjects and in patients with congestive heart failure. In addition to its direct influence on myocardial contractility, dobutamine may significantly modulate vascular tone because of its alpha- and beta-adrenergic agonist activity. ME...

journal_title：Circulation

authors： Binkley PF,Murray KD,Watson KM,Myerowitz PD,Leier CV

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:In patients with asymptomatic valvular aortic stenosis, exercise testing may help to stratify the clinical risk. However, data are limited, and the role of quantitative exercise Doppler echocardiography has never been investigated. METHODS AND RESULTS:Sixty-nine consecutive patients with severe asymptomatic...

journal_title：Circulation

authors： Lancellotti P,Lebois F,Simon M,Tombeux C,Chauvel C,Pierard LA

更新日期：2005-08-30 00:00:00

abstract：BACKGROUND:Although clopidogrel is used to prevent subacute stent thrombosis, its safety and efficacy have not been compared with ticlopidine in a randomized manner in the United States. METHODS AND RESULTS:Patients with successful intracoronary stent implantation were randomly assigned to therapy with ticlopidine or ...

journal_title：Circulation

authors： Taniuchi M,Kurz HI,Lasala JM

更新日期：2001-07-31 00:00:00

abstract：BACKGROUND:Prosthetic valve thrombosis during pregnancy is life-threatening for mother and fetus, and the treatment of this complication is unclear. Cardiac surgery in pregnancy is associated with very high maternal and fetal mortality and morbidity. Thrombolytic therapy has rarely been used in these patients. The aim ...

journal_title：Circulation

authors： Özkan M,Çakal B,Karakoyun S,Gürsoy OM,Çevik C,Kalçık M,Oğuz AE,Gündüz S,Astarcioglu MA,Aykan AÇ,Bayram Z,Biteker M,Kaynak E,Kahveci G,Duran NE,Yıldız M

更新日期：2013-07-30 00:00:00

abstract：:Over the last 20 years, operative mortality has decreased and late survival has improved for patients with chronic stable angina who have coronary artery bypass surgery. However, this favorable trend may not continue because the operation is now extended to elderly and high-risk patients. The most powerful predictors ...

journal_title：Circulation

authors： Gersh BJ,Califf RM,Loop FD,Akins CW,Pryor DB,Takaro TC

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Endocarditis related to pacemaker (PM)-lead infection is a rare but serious complication of permanent transvenous pacing. To determine in which situations the diagnosis should be evoked and to determine optimal management, we reviewed our experience with endocarditis related to PM-lead infection. METHODS AN...

journal_title：Circulation

authors： Klug D,Lacroix D,Savoye C,Goullard L,Grandmougin D,Hennequin JL,Kacet S,Lekieffre J

更新日期：1997-04-15 00:00:00

abstract：BACKGROUND:Mutations in sarcomere protein, PRKAG2, LAMP2, alpha-galactosidase A (GLA), and several mitochondrial genes can cause rare familial cardiomyopathies, but their contribution to increased left ventricular wall thickness (LVWT) in the community is unknown. METHODS AND RESULTS:We studied 1862 unrelated particip...

journal_title：Circulation

authors： Morita H,Larson MG,Barr SC,Vasan RS,O'Donnell CJ,Hirschhorn JN,Levy D,Corey D,Seidman CE,Seidman JG,Benjamin EJ

更新日期：2006-06-13 00:00:00

abstract：:The continuity equation suggests that a ratio of velocities at two different cardiac valves is inversely proportional to the ratio of cross-sectional areas of the valves. To determine whether a ratio of mitral/aortic valve orifice velocities is useful in determining aortic valve area in patients with aortic stenosis, ...

journal_title：Circulation

authors： Richards KL,Cannon SR,Miller JF,Crawford MH

更新日期：1986-05-01 00:00:00

abstract：:Contrary to opinions generally accepted in the past, CHD is very common in both African-American men and women, with incidence rates approaching those of US Caucasians. Higher prevalence of hypertension, diabetes, cigarette smoking, and obesity all contribute to the high level of CHD in African-Americans. Additional r...

journal_title：Circulation

authors： Curry CL

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:We have reported that there is a limitation of exercise capacity in mice with defects in the expression of endothelial nitric oxide (NO) synthase, which is associated with a greater increase in whole-body oxygen consumption (VO2). We hypothesized that in states in which superoxide anion (O2-) is increased, e...

journal_title：Circulation

authors： Kinugawa S,Wang Z,Kaminski PM,Wolin MS,Edwards JG,Kaley G,Hintze TH

更新日期：2005-03-29 00:00:00

abstract：BACKGROUND:The signal transduction mechanism linking mitochondrial ATP synthesis with cytosolic ATP utilization in heart changes during postnatal development in vivo. This maturational process occurs in parallel with accumulation of mitochondrial adenine nucleotide translocator (ANT), which provides a possible site for...

journal_title：Circulation

authors： Portman MA,Xiao Y,Qian K,Tucker RL,Parish SM,Ning XH

更新日期：2000-09-12 00:00:00

abstract：BACKGROUND:Right ventricular (RV) dilatation that occurs as a consequence of RV infarction is thought to produce hemodynamic instability by reducing left ventricular (LV) preload and compliance. We hypothesized that these geometric changes may also adversely affect LV systolic performance. METHODS AND RESULTS:Twelve 4...

journal_title：Circulation

authors： Brookes C,Ravn H,White P,Moeldrup U,Oldershaw P,Redington A

更新日期：1999-08-17 00:00:00

abstract：BACKGROUND:Clinical depression is associated with an increased risk for mortality in patients with a recent myocardial infarction (MI). Reduced heart rate variability (HRV) has been suggested as a possible explanation for this association. The purpose of this study was to determine if depression is associated with redu...

journal_title：Circulation

authors： Carney RM,Blumenthal JA,Stein PK,Watkins L,Catellier D,Berkman LF,Czajkowski SM,O'Connor C,Stone PH,Freedland KE

更新日期：2001-10-23 00:00:00

abstract：:Ventricular mural thrombi complicate many cardiac diseases. The endocardial endothelium can modulate the mechanical performance of subjacent myocardium and mediate responses to certain physiopharmacologic agents. We studied the effects of aggregating platelets on the contractile performance of isolated cardiac muscle....

journal_title：Circulation

authors： Shah AM,Meulemans AL,Brutsaert DL

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Calcium-insensitive transient outward current (I(to)) is important to the development of cardiac memory (CM), which itself reflects the capacity of the heart to remodel electrophysiologically. We used cardiac pacing to test the hypothesis that CM evolution can be explained by developmental maturation of I(to...

journal_title：Circulation

authors： Plotnikov AN,Sosunov EA,Patberg KW,Anyukhovsky EP,Gainullin RZ,Shlapakova IN,Krishnamurthy G,Danilo P Jr,Rosen MR

更新日期：2004-08-03 00:00:00

abstract：:For patients with stenotic native valves, the modified Bernoulli equation (delta P = 4V2) may be applied to Doppler-measured transvalvular velocities to yield an accurate estimate of transvalvular gradients. Although it would be useful if the same approach could be used for those with stenotic prosthetic valves, no pr...

journal_title：Circulation

authors： Wilkins GT,Gillam LD,Kritzer GL,Levine RA,Palacios IF,Weyman AE

更新日期：1986-10-01 00:00:00

abstract：:In 1948 knowledge of the role of the central nervous system in controlling blood pressure was rudimentary and the possibility that the brain could contribute to hypertension was barely acknowledged. Over the past 35 years the development of new technologies, particularly those of the neurosciences, and their applicati...

journal_title：Circulation

authors： Reis DJ

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Smoking cessation is a key component of secondary cardiovascular disease prevention. Varenicline, a partial alpha4beta2 nicotinic acetylcholine receptor agonist, is effective for smoking cessation in healthy smokers, but its efficacy and safety in smokers with cardiovascular disease are unknown. METHODS AND...

journal_title：Circulation

authors： Rigotti NA,Pipe AL,Benowitz NL,Arteaga C,Garza D,Tonstad S

更新日期：2010-01-19 00:00:00

abstract：:Experimental studies of animals have previously demonstrated the validity of [1-11C]acetate as a tracer of oxidative metabolism for use with positron emission tomography. The present study was undertaken to define in normal human volunteers the relation between myocardial clearance kinetics of [1-11C]acetate, and the ...

journal_title：Circulation

authors： Armbrecht JJ,Buxton DB,Brunken RC,Phelps ME,Schelbert HR

更新日期：1989-10-01 00:00:00

abstract：:This is the first scientific statement from the American Heart Association on maternal resuscitation. This document will provide readers with up-to-date and comprehensive information, guidelines, and recommendations for all aspects of maternal resuscitation. Maternal resuscitation is an acute event that involves many ...

journal_title：Circulation

authors： Jeejeebhoy FM,Zelop CM,Lipman S,Carvalho B,Joglar J,Mhyre JM,Katz VL,Lapinsky SE,Einav S,Warnes CA,Page RL,Griffin RE,Jain A,Dainty KN,Arafeh J,Windrim R,Koren G,Callaway CW,American Heart Association Emergency Cardio

更新日期：2015-11-03 00:00:00

abstract：:The ability of 67Ga citrate and 99mTc pyrophosphate cardiac imaging to detect myocarditis was assessed in an experimental rabbit model. Twenty-three rabbits were imaged approximately 72 hours after infusion of i.v. norepinephrine. Diffuse cardiac uptake was found in 13 of 15 rabbits scanned with 67Ga. Tissue distribut...

journal_title：Circulation

authors： Reeves WC,Jackson GL,Flickinger FW,Kwee HG,Schwiter EJ,Werner J,Whitesell L,Biddle MA,Copenhaver G,Shaikh BS,Zelis R

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:The time constant of ventricular relaxation (tau) is a quantitative measure of diastolic performance requiring intraventricular pressure recording. This study validates in humans an equation relating tau to left ventricular pressure at peak -dP/dt (P0), pressure at mitral valve opening (PMV), and isovolumic ...

journal_title：Circulation

authors： Scalia GM,Greenberg NL,McCarthy PM,Thomas JD,Vandervoort PM

更新日期：1997-01-07 00:00:00

abstract：BACKGROUND:Apoptosis contributes to cell loss after ischemia/reperfusion injury in the heart. This study describes the time course and level of apoptosis in different cell types in the intact heart during ischemia/reperfusion injury. METHODS AND RESULTS:Isolated Langendorff-perfused rat hearts were subjected to perfus...

journal_title：Circulation

authors： Scarabelli T,Stephanou A,Rayment N,Pasini E,Comini L,Curello S,Ferrari R,Knight R,Latchman D

更新日期：2001-07-17 00:00:00

abstract：:An experimental approach is described to quantitate inhomogeneity in extracellular K concentration ([K+]out) in the presence of ischemia and to relate this inhomogeneity to the electrophysiologic changes. Extracellular potassium concentration and local direct-current electrograms from the same sites were measured in i...

journal_title：Circulation

authors： Coronel R,Fiolet JW,Wilms-Schopman FJ,Schaapherder AF,Johnson TA,Gettes LS,Janse MJ

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:We sought to separately examine the effects of either weight loss or diets varying in protein content and glycemic index without further changes in body weight on cardiovascular risk factors within the Diet, Obesity, and Genes study (DiOGenes). METHODS AND RESULTS:DiOGenes is a pan-European controlled dieta...

journal_title：Circulation

authors： Gögebakan O,Kohl A,Osterhoff MA,van Baak MA,Jebb SA,Papadaki A,Martinez JA,Handjieva-Darlenska T,Hlavaty P,Weickert MO,Holst C,Saris WH,Astrup A,Pfeiffer AF,DiOGenes.

更新日期：2011-12-20 00:00:00