A nonparametric method for automatic correction of intensity nonuniformity in MRI data.

Abstract:

:A novel approach to correcting for intensity nonuniformity in magnetic resonance (MR) data is described that achieves high performance without requiring a model of the tissue classes present. The method has the advantage that it can be applied at an early stage in an automated data analysis, before a tissue model is available. Described as nonparametric nonuniform intensity normalization (N3), the method is independent of pulse sequence and insensitive to pathological data that might otherwise violate model assumptions. To eliminate the dependence of the field estimate on anatomy, an iterative approach is employed to estimate both the multiplicative bias field and the distribution of the true tissue intensities. The performance of this method is evaluated using both real and simulated MR data.

journal_name

IEEE Trans Med Imaging

authors

Sled JG,Zijdenbos AP,Evans AC

doi

10.1109/42.668698

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

87-97

issue

1

eissn

0278-0062

issn

1558-254X

journal_volume

17

pub_type

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