Abstract:
:An exceptionally smooth and glossy morphotype of Mycobacterium tuberculosis complex was isolated from a 56-year-old Swiss patient with mesenteric tuberculosis. Direct 16S rRNA sequence analysis of the hypervariable signature gene regions revealed a 100% homology to the specific M. tuberculosis complex sequence. Spoligotyping and restriction fragment length polymorphism analyses using the insertion sequences IS6110 and IS1081 and the polymorphic GC-rich sequence as additional genetic markers identified the isolate as the novel taxon M. canettii. Like a Somali child with a similar case, this patient probably contracted the infection in Africa, which raises questions about the geographic distribution of M. canettii.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Pfyffer GE,Auckenthaler R,van Embden JD,van Soolingen Ddoi
10.3201/eid0404.980414subject
Has Abstractpub_date
1998-10-01 00:00:00pages
631-4issue
4eissn
1080-6040issn
1080-6059journal_volume
4pub_type
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