Mycobacterium canettii, the smooth variant of M. tuberculosis, isolated from a Swiss patient exposed in Africa.

Abstract:

:An exceptionally smooth and glossy morphotype of Mycobacterium tuberculosis complex was isolated from a 56-year-old Swiss patient with mesenteric tuberculosis. Direct 16S rRNA sequence analysis of the hypervariable signature gene regions revealed a 100% homology to the specific M. tuberculosis complex sequence. Spoligotyping and restriction fragment length polymorphism analyses using the insertion sequences IS6110 and IS1081 and the polymorphic GC-rich sequence as additional genetic markers identified the isolate as the novel taxon M. canettii. Like a Somali child with a similar case, this patient probably contracted the infection in Africa, which raises questions about the geographic distribution of M. canettii.

journal_name

Emerg Infect Dis

authors

Pfyffer GE,Auckenthaler R,van Embden JD,van Soolingen D

doi

10.3201/eid0404.980414

subject

Has Abstract

pub_date

1998-10-01 00:00:00

pages

631-4

issue

4

eissn

1080-6040

issn

1080-6059

journal_volume

4

pub_type

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