Immunity to mumps before and after MMR vaccination at 12 years of age in the first generation offered the two-dose immunization programme.

abstract：:Bovine tuberculosis (bTB) is increasing in incidence in the UK. Effective control strategies could involve vaccination; BCG, either alone or in prime-boost strategies, remains the most effective vaccine against bovine tuberculosis. However, BCG vaccination of cattle would require development of diagnostic tests able t...

journal_title：Vaccine

authors： Sopp P,Coad M,Hewinson G,Howard CJ,Cheallaigh CN,Keane J,Harris J,Hope JC

更新日期：2008-10-09 00:00:00

abstract：:Persistence of antibodies following a single dose of Tdap vaccine (tetanus, diphtheria, and five-component acellular pertussis vaccine for use in individuals past childhood) was evaluated in a follow-up of adolescents (N=324) and adults (N=644) who had received Tdap in earlier clinical trials. Outcome measures were se...

journal_title：Vaccine

authors： Barreto L,Guasparini R,Meekison W,Noya F,Young L,Mills E

更新日期：2007-11-23 00:00:00

abstract：:The efficacy of a vaccine is based primarily on the adherence of the subject to the immunization schedule. This paper compares the compliance rates (CR) for the third dose of hepatitis B virus (HBV) vaccine given according to one of two vaccination schedules among subjects attending two sexually transmitted disease (S...

journal_title：Vaccine

authors： Dal-Ré R,González A,Ramirez V,Ballesteros J,del Romero J,Bru F

更新日期：1995-02-01 00:00:00

abstract：:Pre-fusion stabilizing mutations (DS-Cav1) in soluble fusion (F) proteins of human respiratory syncytial virus (RSV) were previously reported. Here we investigated the antigenic and immunogenic properties of pre-fusion like RSV F proteins on enveloped virus-like particles (VLP). Additional mutations were introduced to...

journal_title：Vaccine

authors： Kwon YM,Lee Y,Kim KH,Jung YJ,Li Z,Jeeva S,Lee S,Moore ML,Kang SM

更新日期：2019-10-16 00:00:00

abstract：:A formalin-inactivated red sea bream iridovirus (RSIV) vaccine was prepared using the culture supernatant of a persistently infected Pagrus major fin cell line (PI-PMF) with IVS-1 strain (RSIV subtype II Meglaocytivirus). Rock bream (Oplegnathus fasciatus) were injected with a high-dose, ultracentrifuged megalocytivir...

journal_title：Vaccine

authors： Kwon WJ,Choi JC,Hong S,Kim YC,Jeong MG,Min JG,Jeong JB,Kim KI,Jeong HD

更新日期：2020-12-03 00:00:00

abstract：:A post-marketing study was conducted in 26 paediatric practices in Germany to collect safety information on the virosomal adjuvanted influenza vaccine Inflexal V (in Germany marketed as Infectovac Flu). Children aged 6 months to 6 years received one or two doses. Adverse events were documented by parents/legal guardia...

journal_title：Vaccine

authors： Künzi V,Dornseiff M,Horwath J,Hartmann K

更新日期：2009-02-18 00:00:00

abstract：:Experimental whole-parasite immunization through concurrent administration of infectious Plasmodium sporozoites with drugs that prevent pathogenic blood-stage infection represents the current benchmark in malaria vaccine development. Key questions concerning translation remain, including the requirement for single-dos...

journal_title：Vaccine

authors： Pfeil J,Sepp KJ,Heiss K,Meister M,Mueller AK,Borrmann S

更新日期：2014-10-14 00:00:00

abstract：:The hepatitis E virus (HEV) vaccine, Hecolin(®), was licensed in China for the prevention of HEV infection and HEV-related diseases with demonstrated safety and efficacy [1,2]. The vaccine is composed of a truncated HEV capsid protein, p239, as the sole antigen encoded by open reading frame 2 and produced using Escher...

journal_title：Vaccine

authors： Zhang X,Wei M,Pan H,Lin Z,Wang K,Weng Z,Zhu Y,Xin L,Zhang J,Li S,Xia N,Zhao Q

更新日期：2014-07-07 00:00:00

abstract：:We studied with a mouse model and in piglets the requirements to prime for a secondary, mucosal B-cell response against Escherichia coli F4 fimbriae, an important virulence factor of enterotoxigenic E. coli, the agent associated with postweaning diarrhoea in piglets. The major observation obtained with the mouse model...

journal_title：Vaccine

authors： Bianchi AT,Scholten JW,van Zijderveld AM,van Zijderveld FG,Bokhout BA

更新日期：1996-02-01 00:00:00

abstract：:The compatibility, safety and interaction on antibody induction of a combined vaccine application were assessed. Specific pathogen-free cats were vaccinated with either a modified live virus vaccine containing feline calici- (FCV), herpes- (FHV-1), parvovirus (FPV) and Chlamydophila felis (C. felis), an adjuvanted rec...

journal_title：Vaccine

authors： Brunner C,Kanellos T,Meli ML,Sutton DJ,Gisler R,Gomes-Keller MA,Hofmann-Lehmann R,Lutz H

更新日期：2006-03-10 00:00:00

abstract：:To determine the distribution of rotavirus strains and facilitate vaccine policy decisions in Taiwan, active hospital-based gastroenteritis surveillance was conducted in three sentinel hospitals. From 1 January 2005 to 31 December 2007, a total of 3435 children less than 5 years old with gastroenteritis were enrolled....

journal_title：Vaccine

authors： Wu FT,Liang SY,Tsao KC,Huang CG,Lin CY,Lin JS,Su CY,Eng HL,Yang JY,Chen PJ,Yang CF

更新日期：2009-11-20 00:00:00

abstract：:Immunization by convergent combinatorial peptide libraries, or 'mixotopes' represents an interesting approach for inducing broadly cross-reactive immune response to hypervariable pathogens. The authors have immunized rabbits with a series of eight HIV-1 V3-loop derived constructs of increasing complexity, and analysed...

journal_title：Vaccine

authors： Gras-Masse H,Boutillon C,Diesis E,Deprez B,Tartar A

更新日期：1997-10-01 00:00:00

abstract：:Inactivated influenza vaccine is recommended for routine use in high-risk individuals in the United States, including women who will be in the second or third trimesters of pregnancy. The basis for this recommendation is the high risk of exposure and disease due to influenza viruses in pregnant women, as well as the i...

journal_title：Vaccine

authors： Englund JA

更新日期：2003-07-28 00:00:00

abstract：:Streptococcus pneumoniae is one of the leading bacterial pathogens causing invasive disease and non-invasive infections at both extremes of life: in children younger than 5 years and in elderly persons of 65 years or more. Pneumococcal infections result in substantial morbidity and mortality among children under 5 yea...

journal_title：Vaccine

authors： Arguedas A,Soley C,Abdelnour A

更新日期：2011-09-14 00:00:00

abstract：:The prevalence of seropositive individuals that makes costs of vaccinating all individuals equal to that for screening and vaccination of susceptible individuals is defined as the critical prevalence of antibodies (p*). Screening and vaccination is more efficient when the prevalence of seropositive individuals (p) in ...

journal_title：Vaccine

authors： Plans-Rubió P

更新日期：2004-09-28 00:00:00

abstract：:Neutralizing antibody is associated with the prevention and clearance of influenza virus infection. Microneutralization (MN) and hemagglutination inhibition (HI) assays are currently used to evaluate neutralizing antibody responses against human and avian influenza viruses, including H5N1. The MN assay is somewhat lab...

journal_title：Vaccine

authors： Tsai C,Caillet C,Hu H,Zhou F,Ding H,Zhang G,Zhou B,Wang S,Lu S,Buchy P,Deubel V,Vogel FR,Zhou P

更新日期：2009-11-12 00:00:00

abstract：BACKGROUND:Rotavirus (RV) infection is the primary cause of severe gastroenteritis in children aged <5 years in Germany and worldwide. In 2013 the German Standing Committee on Vaccination (STIKO) developed a national recommendation for routine RV-immunization of infants. To support informed decision-making we predicted...

journal_title：Vaccine

authors： Weidemann F,Dehnert M,Koch J,Wichmann O,Höhle M

更新日期：2014-09-08 00:00:00

abstract：:Livestock production is a fundamental source of revenue and nutrition, wherein cattle-farming constitutes one of the major agricultural industries. Vectors and vector-borne diseases constitute one of the major factors that decrease the livelihood of all farming communities, more so in resource-poor communities and dev...

journal_title：Vaccine

authors： Robbertse L,Richards SA,Stutzer C,Olivier NA,Leisewitz AL,Crafford JE,Maritz-Olivier C

更新日期：2020-10-14 00:00:00

abstract：:To facilitate site-directed chemical coupling of antigens to the heat labile enterotoxin B subunit of Escherichia coli (LTB), a series of genetically modified fusion proteins of LTB were constructed. The LTB fusion proteins had modified versions of a short (14 amino acid) spacer epitope called the Pk tag attached at t...

journal_title：Vaccine

authors： O'Dowd AM,Botting CH,Precious B,Shawcross R,Randall RE

更新日期：1999-03-17 00:00:00

abstract：:We developed a rapid and sensitive diagnosis system for H5N1 highly pathogenic avian influenza (HPAI) virus infection using an unique gene amplification method, reverse transcriptase loop-mediated isothermal amplification (RT-LAMP). The sensitivity of the system was found to be 100-fold higher than that of ordinary on...

journal_title：Vaccine

authors： Imai M,Ninomiya A,Minekawa H,Notomi T,Ishizaki T,Tashiro M,Odagiri T

更新日期：2006-11-10 00:00:00

abstract：:The amino terminal region of group A streptococcal M proteins evokes type-specific immunity while the conserved C-repeat epitopes evoke cross-protective immunity against multiple serotypes. The present studies were undertaken to compare the protective efficacy of vaccines containing either type-specific (hexavalent va...

journal_title：Vaccine

authors： Penfound TA,Chiang EY,Ahmed EA,Dale JB

更新日期：2010-07-12 00:00:00

abstract：:Using HIV-1 envelope protein (Env)-based immunogens that closely mimic the conformation of functional HIV-1 Envs and represent the isolates prevalent in relevant geographical region is considered a rational approach towards developing HIV vaccine. We recently reported that like clade B Env, JRFL, membrane bound Indian...

journal_title：Vaccine

authors： Shrivastava T,Samal S,Tyagi AK,Goswami S,Kumar N,Ozorowski G,Ward AB,Chakrabarti BK

更新日期：2018-03-14 00:00:00

abstract：:Yellow fever is an acute infectious disease caused by prototype virus of the genus Flavivirus. It is endemic in Africa and South America where it represents a serious public health problem causing epidemics of hemorrhagic fever with mortality rates ranging from 20% to 50%. There is no available antiviral therapy and v...

journal_title：Vaccine

authors： Pereira RC,Silva AN,Souza MC,Silva MV,Neves PP,Silva AA,Matos DD,Herrera MA,Yamamura AM,Freire MS,Gaspar LP,Caride E

更新日期：2015-08-20 00:00:00

abstract：:At present, the seed viruses for the manufacture of licensed seasonal inactivated influenza vaccines in the United States are derived from primary egg isolates as a result of concerns associated with adventitious agents. According to the prevailing view, the passage of influenza viruses through eggs serves as a filter...

journal_title：Vaccine

authors： Murata H,Macauley J,Lewis AM Jr,Peden K

更新日期：2011-04-12 00:00:00

abstract：:This study assessed (1) T-cell responses following vaccination of HIV-1 negative volunteers with HIV-1LAI recombinant gp160 (rgp160) vaccine, and (2) effects of vaccine injection schedule and MHC HLA type on those responses. In one trial, volunteers received rgp160 in two accelerated schedules (Groups 1 and 2). In the...

journal_title：Vaccine

authors： Gorse GJ,Patel GB,Newman FK,Mandava M,Belshe RB

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Gram-negative bacteria (GNB) are a leading cause of nosocomial infection and sepsis. Increasing multi-antibiotic resistance has left clinicians with fewer therapeutic options. Antibodies to GNB lipopolysaccharide (LPS, or endotoxin) have reduced morbidity and mortality as a result of infection and are not su...

journal_title：Vaccine

authors： Cross AS,Greenberg N,Billington M,Zhang L,DeFilippi C,May RC,Bajwa KK

更新日期：2015-11-27 00:00:00

abstract：:The efficacy of a novel inactivated Lawsonia intracellularis vaccine, Porcilis® Lawsonia, was compared to that of a commercially available live attenuated vaccine in three experimental vaccination-challenge studies in pigs. The efficacy of the new vaccine was further tested under field conditions on a farm with a hist...

journal_title：Vaccine

authors： Jacobs AAC,Harks F,Hazenberg L,Hoeijmakers MJH,Nell T,Pel S,Segers RPAM

更新日期：2019-04-03 00:00:00

abstract：:The immunogenicity of proteins encapsulated in poly(DL-lactide-co-glycolide) (PLG) microspheres has not been investigated to any extent in large animal models. In this study, IgG and IgA responses to ovalbumin (OVA), encapsulated in microspheres was investigated following intranasal inoculation into calves. Scanning e...

journal_title：Vaccine

authors： Kavanagh OV,Earley B,Murray M,Foster CJ,Adair BM

更新日期：2003-10-01 00:00:00

abstract：:Outer membrane proteins (OMP) are expressed in Gram-negative bacterial cell wall. OmpA from Klebsiella pneumoniae (KpOmpA) has been shown to bind and to activate selectively antigen presenting cells (APCs), eliciting protective CTL responses. In this study, we investigated whether OmpX, another member of the OMP famil...

journal_title：Vaccine

authors： Maisnier-Patin K,Malissard M,Jeannin P,Haeuw JF,Corbière JC,Hoeffel G,Gauchat JF,Nguyen T,Saez JM,Delneste Y

更新日期：2003-09-08 00:00:00

abstract：:Successful vaccination of mice against an otherwise lethal challenge with the Peru strain of Trypanosoma cruzi necessitates the induction of a strong cell mediated immune response. Previously, immunization of mice with the paraflagellar rod proteins from Trypanosoma cruzi90% reduction in parasitemia in immunized mice ...

journal_title：Vaccine

authors： Wrightsman RA,Manning JE

更新日期：2000-01-31 00:00:00