Pathology information systems: data mining leads to knowledge discovery.

Abstract:

:Information systems in pathology provide opportunities for pathologists and clinical laboratory scientists to impact both clinical care and modern research agendas. The paradigm shift in health care from individualized care to population-based and standardized delivery systems has created both of these opportunities. In research, pathology information systems can provide key databases for health services research and new informatics-based approaches to database research. The latter is characterized by utilization of pathology databases for data mining to discover new patterns that provide new knowledge. The multidisciplinary knowledge discovery and data mining program at the University of Alabama at Birmingham focuses on this health care application, which has the potential to make a major impact on health care research and delivery.

journal_name

Arch Pathol Lab Med

authors

McDonald JM,Brossette S,Moser SA

subject

Has Abstract

pub_date

1998-05-01 00:00:00

pages

409-11

issue

5

eissn

0003-9985

issn

1543-2165

journal_volume

122

pub_type

杂志文章
  • Use of a clinical laboratory database to estimate Toxoplasma seroprevalence among human immunodeficiency virus-infected patients. Overcoming bias in secondary analysis of clinical records.

    abstract::Knowledge of Toxoplasma seroprevalence among human immunodeficiency virus-infected patients identifies candidates for potential prophylaxis and may influence management among patients who present with mass lesions of the central nervous system. Toxoplasma antibody seroprevalence among persons with human immunodeficien...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Mathews WC,Fullerton SC

    更新日期:1994-08-01 00:00:00

  • Primary non-Hodgkin's lymphoma of the heart in two patients with the acquired immunodeficiency syndrome.

    abstract::We report two cases of primary cardiac lymphoma that developed in patients suffering from the acquired immunodeficiency syndrome. Both cases of lymphoma were histologically aggressive as generally observed in patients with the acquired immunodeficiency syndrome. The lymphoma cells in the center of a tumor nodule obtai...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Guarner J,Brynes RK,Chan WC,Birdsong G,Hertzler G

    更新日期:1987-03-01 00:00:00

  • Basal-like breast cancer: update on clinicopathologic, immunohistochemical, and molecular features.

    abstract:CONTEXT:Basal-like breast carcinoma (BLBC) is a distinct molecular subtype of breast carcinoma identified through gene expression profiling studies. OBJECTIVE:To provide the clinical background, the histologic profile, and the immunohistochemical profile of these tumors and discuss the current knowledge of their molec...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.5858/arpa.2012-0439-RA

    authors: Leidy J,Khan A,Kandil D

    更新日期:2014-01-01 00:00:00

  • American Joint Committee on Cancer Staging and clinicopathological high-risk predictors of ocular surface squamous neoplasia: a study from a tertiary eye center in India.

    abstract:CONTEXT:Ocular surface squamous neoplasia (OSSN) is the most common tumor of conjunctival epithelium associated with risk of permanent visual impairment. It includes conjunctival intraepithelial neoplasia and squamous cell carcinoma. Although American Joint Committee on Cancer-TNM (AJCC-TNM) staging is commonly used in...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2013-0353-OA

    authors: Chauhan S,Sen S,Sharma A,Tandon R,Kashyap S,Pushker N,Vanathi M,Sharma N

    更新日期:2014-11-01 00:00:00

  • Immunohistochemistry in undifferentiated neoplasm/tumor of uncertain origin.

    abstract:CONTEXT:Immunohistochemistry has become an indispensable ancillary study in the identification and classification of undifferentiated neoplasms/tumors of uncertain origin. The diagnostic accuracy has significantly improved because of the continuous discoveries of tissue-specific biomarkers and the development of effect...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.5858/arpa.2014-0061-RA

    authors: Lin F,Liu H

    更新日期:2014-12-01 00:00:00

  • Intraosseous lipoma. A clinicopathologic study of four cases.

    abstract::We describe the clinical, radiologic, and pathologic features of four cases of intraosseous lipoma. The patients ranged in age from 37 to 48 years, and three of them were men. Three patients presented with pain; in the fourth patient, the lesion was discovered incidentally. The involved bones were distal radius (in on...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Barcelo M,Pathria MN,Abdul-Karim FW

    更新日期:1992-09-01 00:00:00

  • Gastric myeloid metaplasia: a case report and review of the literature.

    abstract::We report a case of gastric myeloid metaplasia in an 89- year-old woman with agnogenic myeloid metaplasia. The lesions were fortuitously discovered on upper endoscopy. The antral mucosa was thickened and polypoid, and on histologic examination contained immature granulocytes, megakaryocytes, and a few erythroblasts wi...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/1543-2165(2004)128<568:GMMACR>2.0.CO;2

    authors: Chatelain D,Devendeville A,Rudelli A,Bruniau A,Geslin G,Sevestre H

    更新日期:2004-05-01 00:00:00

  • Improved technique for cutting brain slices.

    abstract::When two disposable serological pipettes with an external diameter of 1 cm are placed on the cutting surface on either side of the brain and the knife rides across them, it will cut even slices precisely 1 cm thick. Both coronal and horizontal slices can be cut as well as oblique slices for comparison with computerize...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Kaufmann JC

    更新日期:1979-01-01 00:00:00

  • Pulmonary hypertension associated with systemic lupus erythematosus: predominantly thrombotic arteriopathy accompanied by plexiform lesions.

    abstract::We report an autopsy case of pulmonary hypertension associated with systemic lupus erythematosus in a 48-year-old woman. After 8-year follow-up under a definite diagnosis of systemic lupus erythematosus, she experienced gradually developing exertional dyspnea with palpitation. Her chest x-ray showed clear lung fields ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Yokoi T,Tomita Y,Fukaya M,Ichihara S,Kakudo K,Takahashi Y

    更新日期:1998-05-01 00:00:00

  • Liposarcoma of the pleural cavity: clinical and pathologic features of 4 cases with a review of the literature.

    abstract:BACKGROUND:Primary liposarcomas of the pleura are extremely rare malignancies, and relatively few reports appear in the world literature. DESIGN:We compiled a small series of 4 cases of primary pleural liposarcoma from the files of the Armed Forces Institute of Pathology (Washington, DC) and compared the histopatholog...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/0003-9985(2000)124<0699:LOTPC>2.0.CO;2

    authors: Okby NT,Travis WD

    更新日期:2000-05-01 00:00:00

  • Primary renal synovial sarcoma confirmed by cytogenetic analysis: a lesion distinct from sarcomatoid renal cell carcinoma.

    abstract::Primary synovial sarcoma rarely originates in the renal parenchyma. When this occurs, origin of this unusual tumor type has been the subject of debate in the literature, with a suggestion that previously reported cases may be more correctly described as renal cell carcinoma with sarcomatoid dedifferentiation. Synovial...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2005)129<238:PRSSCB>2.0.CO;2

    authors: Shannon BA,Murch A,Cohen RJ

    更新日期:2005-02-01 00:00:00

  • The bile duct adenoma. A lesion distinct from Meyenburg complex.

    abstract::We studied 16 cases of bile duct adenomas, lesions that are distinct from Meyenburg complex. The former lesion is made up of small tubular structures with little or no lumen, is usually single and subcapsular, and is unrelated to cystic disease. It must be differentiated from early carcinoma. Of the six cases encounte...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Govindarajan S,Peters RL

    更新日期:1984-11-01 00:00:00

  • The assessment of pathologists/laboratory medicine physicians through a multisource feedback tool.

    abstract:CONTEXT:There is increasing interest in ensuring that physicians demonstrate the full range of Accreditation Council for Graduate Medical Education competencies. OBJECTIVE:To determine whether it is possible to develop a feasible and reliable multisource feedback instrument for pathologists and laboratory medicine phy...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165-133.8.1301

    authors: Lockyer JM,Violato C,Fidler H,Alakija P

    更新日期:2009-08-01 00:00:00

  • Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents.

    abstract:CONTEXT:Lung cancer is the number one cause of cancer deaths in the United States and globally. The advent of targeted therapies has offered a new treatment paradigm for lung cancer, but currently validated and emerging drugs are effective in only a small minority of lung cancers, predominantly adenocarcinomas. Folate ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2012-0176-OA

    authors: Cagle PT,Zhai QJ,Murphy L,Low PS

    更新日期:2013-02-01 00:00:00

  • Touch imprints: their use in the frozen-section diagnosis of alveolar soft-part sarcoma.

    abstract::A case of alveolar soft-part sarcoma was studied. It illustrates the use of touch imprint preparations on fresh tissue sections examined while frozen. The technique is simple to use and can be applied to a wide variety of neoplastic and inflammatory lesions. Touch imprints substantially contribute to accurate histopat...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: McDonald EC,Haughton W,Lute K

    更新日期:1981-05-01 00:00:00

  • Malignant lymphoma with primary presentation in the spleen. A study of 20 patients.

    abstract::We describe 20 adult patients with malignant lymphoma with primary presentation in the spleen. The most common presenting symptoms were fever, malaise, and weight loss. Physical examination revealed prominent splenomegaly without palpable lymphadenopathy. Small lymphocytic lymphoma was the most frequent histologic typ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Spier CM,Kjeldsberg CR,Eyre HJ,Behm FG

    更新日期:1985-12-01 00:00:00

  • Necrobiosis lipoidica in a diabetic intravenous drug user.

    abstract::Necrobiosis lipoidica occurs most commonly on the lower extremities in patients with diabetes; lesions typically occur in the pretibial region. Although the pathogenesis of necrobiosis lipoidica remains unclear, both external trauma and vascular damage have been proposed as contributing to the development of this diso...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Jordan CD,Flotte TJ,Wright SW,MacKool B,Duncan LM

    更新日期:1997-10-01 00:00:00

  • Iron and the liver: subcellular distribution of iron and decreased microsomal cytochrome P-450 in livers of iron-loaded rats.

    abstract::To understand better the intracellular iron distribution and metabolic consequences of chronic hepatic iron overload, rats were given large doses of iron dextran or ferric citrate intraperitoneally. They accumulated large quantities of iron within Kupffer cells and hepatocytes. The relative subcellular iron distributi...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Bonkowsky HL,Carpenter SJ,Healey JF

    更新日期:1979-01-01 00:00:00

  • Update on selected salivary gland neoplasms.

    abstract:CONTEXT:Malignancies of the salivary gland are uncommon and account for 0.3% of all malignancies. In addition to their rarity, diagnosing these tumors can be challenging given the histologic overlap among various subtypes, their morphologic heterogeneity, and the recent recognition of new entities. OBJECTIVE:To provid...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165-133.11.1763

    authors: McHugh JB,Visscher DW,Barnes EL

    更新日期:2009-11-01 00:00:00

  • Myocardium as emboli in the systemic and pulmonary circulation.

    abstract::Myocardium as emboli is a decidedly rare phenomenon. Only three such examples were identified among 8033 consecutive autopsies performed over a ten-year period, 1976 to 1985, an incidence of 0.037%. In two of these three cases, myocardial emboli occurred in the systemic (coronary) circulation. The source of emboli was...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Lie JT

    更新日期:1987-03-01 00:00:00

  • Sturge-Weber syndrome. A case with thyroid and choroid plexus hemangiomas and leptomeningeal melanosis.

    abstract::We studied a case of Sturge-Weber syndrome in a 66-year-old woman, who displayed associated angiomas of the thyroid gland and choroid plexi and leptomeningeal melanosis. These findings are discussed in light of the proposed pathogenesis of the syndrome and its relationship to the other neuroectodermal dysplasias. ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Bentz MS,Towfighi J,Greenwood S,Zaino R

    更新日期:1982-02-01 00:00:00

  • Effective management of hepatitis C molecular testing improves test use without compromising patient management.

    abstract:CONTEXT:The availability of effective antiviral therapy for hepatitis C has increased the need for molecular detection and quantification of circulating hepatitis C viral particles. The limits of detection differ for the quantitative and qualitative reverse transcriptase polymerase chain reaction (RT-PCR) assays; furth...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2002)126<0100:EMOHCM>2.0.CO;2

    authors: Kukuczka S,Grosso LE

    更新日期:2002-01-01 00:00:00

  • Application of a combined protocol for rational request and utilization of antibody assays improves clinical diagnostic efficacy in autoimmune rheumatic disease.

    abstract:CONTEXT:Because of a marked increase in the number of requests for antinuclear antibodies, anti-extractable nuclear antigen antibodies, and anti-double-stranded DNA antibodies for the diagnosis of autoimmune rheumatic disease, guidelines have been proposed for their appropriate use. OBJECTIVE:To evaluate in terms of c...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2007)131[112:AOACPF]2.0.CO;2

    authors: Tampoia M,Brescia V,Fontana A,Zucano A,Morrone LF,Pansini N

    更新日期:2007-01-01 00:00:00

  • Xanthomatous bronchiolitis obliterans with cholesterol pneumonia.

    abstract::Reported is an instance of bronchiolitis obliterans due to the accumulation of lipid-laden cells within bronchiolar walls and lumina. The bronchiolar lining had extensive squamous and goblet cell metaplasia with focal ulceration. Scattered foci of cholesterol pneumonia, composed of acicular crystals with an associated...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Heffelfinger SC,Weilbaecher DG,Lawrence EC,Johnson EH,Greenberg SD

    更新日期:1988-06-01 00:00:00

  • Expression of thyroid transcription factor-1 and other markers in sclerosing hemangioma of the lung.

    abstract:CONTEXT:Sclerosing hemangioma of the lung is well characterized histologically, but the line of differentiation expressed by the tumor cells has been unclear. Despite the implication by its name of a vascular neoplasm, sclerosing hemangioma is considered by most authorities to be an epithelial tumor, possibly related t...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2001)125<1335:EOTTFA>2.0.CO;2

    authors: Illei PB,Rosai J,Klimstra DS

    更新日期:2001-10-01 00:00:00

  • Primary hepatic marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type in a patient with primary biliary cirrhosis.

    abstract::Primary lymphoma of the liver is rare. Recently, marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT) type have been described in the liver. Most of these cases occurred without known underlying liver disease, while others were seen in patients with chronic hepatitis. A case of primary hepatic MA...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2000)124<0604:PHMZBC>2.0.CO;2

    authors: Ye MQ,Suriawinata A,Black C,Min AD,Strauchen J,Thung SN

    更新日期:2000-04-01 00:00:00

  • Comparison of ThinPrep preparations to other preparation types in gastrointestinal cytology: observations from the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology.

    abstract:CONTEXT:Differences in participant responses for ThinPrep (TP) and non-ThinPrep (NTP) preparations for gastrointestinal cytology challenges, which circulated in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology (CAP NGC), may help to identify performance variations betwe...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/2009-0326-CP.1

    authors: Clayton AC,Bentz JS,Wasserman PG,Schwartz MR,Souers RJ,Chmara BA,Laucirica R,Clary KM,Moriarty AT,College of American Pathologists Cytopathology Resource Committee.

    更新日期:2010-08-01 00:00:00

  • Liposuction-Induced Fat Embolism Syndrome: A Brief Review and Postmortem Diagnostic Approach.

    abstract::Lipoplasty, or liposuction, the surgical process of removing excess fat, is an elective procedure with rising frequency in the United States. Fat embolism syndrome is a clinical diagnosis and is defined as fat in the circulation with an identifiable clinical pattern of signs and symptoms (eg, hypoxemia, respiratory in...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.5858/arpa.2017-0117-RS

    authors: Cantu CA,Pavlisko EN

    更新日期:2018-07-01 00:00:00

  • Coronary angiographic findings in patients with clinical unstable angina according to cardiac troponin I and T concentrations in serum.

    abstract:CONTEXT:Elevated cardiac troponin levels have been reported to identify unstable angina patients at high risk. OBJECTIVE:To examine the relation of cardiac troponin I (cTnI) and cardiac troponin T (cTnT) levels to findings of coronary angiography in these patients. METHODS:Samples for troponin estimation were taken e...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2002)126<0448:CAFIPW>2.0.CO;2

    authors: Panteghini M,Cuccia C,Pagani F,Turla C,Bonetti G,Bonini E

    更新日期:2002-04-01 00:00:00

  • Primary rhabdomyosarcoma of the female breast: report of a case and review of the literature.

    abstract::We report the case of a primary breast rhabdomyosarcoma in a 51-year-old white woman. The tumor occupied the upper outer quadrant of the right breast. There was no association with the underlying pectoral muscle, and the patient was free of any other benign or malignant neoplastic processes outside the breast. Microsc...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Kyriazis AP,Kyriazis AA

    更新日期:1998-08-01 00:00:00