Abstract:
:Genetic diversity in the second domain exon of Atlantic salmon (Salmo salar) major histocompatibility complex (Mhc) class I was investigated in two dams and nine of their haploid offspring by means of polymerase chain reaction (PCR) and DNA sequence analysis. A similar study was also performed on nine diploid offspring from one of these dams. The complex segregation patterns and sequence similarities between variants make definitive allele, haplotype and locus assignments difficult. There are, however, indications of six Mhc-Sasa class I loci and a fairly well-defined haplotype of four variants. One non-polymorphic variant present in most specimens could be a salmon analogue to the human non-classical loci.
journal_name
Anim Genetjournal_title
Animal geneticsauthors
Grimholt U,Olsaker I,Lingaas F,Lie Odoi
10.1111/j.1365-2052.1997.00183.xsubject
Has Abstractpub_date
1997-12-01 00:00:00pages
385-90issue
6eissn
0268-9146issn
1365-2052journal_volume
28pub_type
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