The therapeutic environment of psychiatric hospitals in Japan: a comparison of medical welfare facilities for senile dementia.

abstract：AIM:Rare variations are suggested to play a role in the genetic etiology of schizophrenia; to further investigate their role, we performed a three-stage study in a Japanese population. METHODS:In the first stage, we performed whole-exome sequencing (WES) of two parent-affected offspring trios. In the second stage, we ...

journal_title：Psychiatry and clinical neurosciences

authors： Hoya S,Watanabe Y,Hishimoto A,Nunokawa A,Inoue E,Igeta H,Otsuka I,Shibuya M,Egawa J,Sora I,Someya T

更新日期：2017-08-01 00:00:00

abstract：:In the last 10 years, numerous neurobiological studies have been conducted on Internet addiction or Internet use disorder. Various neurobiological research methods - such as magnetic resonance imaging; nuclear imaging modalities, including positron emission tomography and single photon emission computed tomography; mo...

journal_title：Psychiatry and clinical neurosciences

authors： Park B,Han DH,Roh S

更新日期：2017-07-01 00:00:00

abstract：:This study evaluated the effects of the daytime nap on performance, mood and physiological measures in aged individuals Participants were six healthy aged persons (M=72.2 years old) who habitually napped in the afternoon three or more times a week. They participated under two conditions with an interval of 1 week. In ...

journal_title：Psychiatry and clinical neurosciences

authors： Tamaki M,Shirota A,Tanaka H,Hayashi M,Hori T

更新日期：1999-04-01 00:00:00

abstract：AIM:The purpose of this study was to examine the association of Internet overuse with excessive daytime sleepiness (EDS). METHODS:A total of 2336 high school students in South Korea (boys, 57.5%; girls, 42.5%) completed the structured questionnaire. The severity of Internet addiction was evaluated using Young's Intern...

journal_title：Psychiatry and clinical neurosciences

authors： Choi K,Son H,Park M,Han J,Kim K,Lee B,Gwak H

更新日期：2009-08-01 00:00:00

abstract：:We report two cases of transient global amnesia (TGA) diagnosed using a clinical criteria and single photon emission tomography (SPECT) with the aid of Statistical Parametric Mapping (SPM). Both patients underwent an initial SPECT study about 20 h after the disappearance of the amnesic episode, and a second study 3 we...

journal_title：Psychiatry and clinical neurosciences

authors： Asada T,Matsuda H,Morooka T,Nakano S,Kimura M,Uno M

更新日期：2000-12-01 00:00:00

abstract：AIMS:In a previous study it was demonstrated that the anxiolytic action of tandospirone, a 5-hydroxytryptamine (5-HT)(1A) receptor agonist, is facilitated by cytochrome P450 (CYP) 3A4 inhibitors, such as ketoconazole and cimetidine. It is also known that fluvoxamine, a selective serotonin re-uptake inhibitor (SSRI), in...

journal_title：Psychiatry and clinical neurosciences

authors： Nishikawa H,Inoue T,Masui T,Izumi T,Nakagawa S,Koyama T

更新日期：2008-10-01 00:00:00

abstract：AIM:Internet addiction disrupts the daily lives of adolescents. We investigated the prevalence of Internet addiction in junior high school students, elucidated the relation between Internet addiction and mental states, and determined the factors associated with Internet addiction in adolescents. METHODS:Junior high sc...

journal_title：Psychiatry and clinical neurosciences

authors： Kawabe K,Horiuchi F,Ochi M,Oka Y,Ueno S

更新日期：2016-09-01 00:00:00

abstract：:Of the epileptic patients who were treated for > or = 5 years until the end of 1990 and had more than four seizures in 1990, 63 patients had been treated without interruption until the end of 1995. We analyzed their clinical courses from 1990 to 1995 prospectively. More than half the subjects were diagnosed with tempo...

journal_title：Psychiatry and clinical neurosciences

authors： Wada K,Kiryu K,Kawata Y,Chiba T,Mizuno K,Okada M,Tasaki H,Fukushima Y,Saito F,Kaneko S

更新日期：1997-08-01 00:00:00

abstract：:Interleukin-1 (IL1) is an inflammatory cytokine and exerts neurodegenerative effects in the brain. Several studies have indicated that IL1 is likely to be involved in the pathogenesis of schizophrenia. Recent genetic studies have revealed that the IL1 gene complex (IL,1 alpha, IL1, beta and IL1 receptor antagonist) wa...

journal_title：Psychiatry and clinical neurosciences

authors： Watanabe Y,Nunokawa A,Kaneko N,Muratake T,Koizumi M,Someya T

更新日期：2007-08-01 00:00:00

abstract：AIMS:Near-infrared spectroscopy has the potential for aiding the diagnosis of major depressive disorder. The purpose of this study was to systematically review the evidence from observational studies regarding the use of near-infrared spectroscopy in patients with major depressive disorder and to identify the character...

journal_title：Psychiatry and clinical neurosciences

authors： Zhang H,Dong W,Dang W,Quan W,Tian J,Chen R,Zhan S,Yu X

更新日期：2015-01-01 00:00:00

abstract：:This study investigated the hypnotic effects of 10 mg melatonin and placebo, which were administered at 10.00 h, according to a single-blind crossover design, on an 8-h diurnal sleep from 11.00 to 19.00 h, following a full night of sleep. The subjects were six healthy male students, each of whom underwent polysomnogra...

journal_title：Psychiatry and clinical neurosciences

authors： Matsumoto M

更新日期：1999-04-01 00:00:00

abstract：:A female patient exhibiting functional hearing loss in her left ear demonstrated reduced amplitude of P3 component in event-related potentials (ERP) to left monaural stimulation, with preserved N1 and N2 components to stimulation of either ear. This result suggested that stimuli in the affected ear were conducted succ...

journal_title：Psychiatry and clinical neurosciences

authors： Fukuda M,Hata A,Niwa S,Hiramatsu K,Yokokoji M,Hayashida S,Itoh K,Nakagome K,Iwanami A

更新日期：1996-04-01 00:00:00

abstract：:The aim of this study is to show the clinical significance of the differences in arousal response at a termination of apnea/hypopnea between aged and middle-aged patients with obstructive sleep apnea syndrome (OSAS). We polygraphically assessed electrocardiographic (ECG) and electroencephalographic (EEG) arousal. Elec...

journal_title：Psychiatry and clinical neurosciences

authors： Okada T,Hanyu M,Noda A,Kayukawa Y,Ohta T

更新日期：1998-04-01 00:00:00

abstract：:The serum concentrations of total, free and acylcarnitine were compared in 25 patients with multiple sclerosis (MS) and among age- and sex-matched normal controls by the new enzymatic cycling method in order to clarify whether the fatigue in MS might be due to possible carnitine-related fatty acid metabolic abnormalit...

journal_title：Psychiatry and clinical neurosciences

authors： Fukazawa T,Sasaki H,Kikuchi S,Hamada T,Tashiro K

更新日期：1996-12-01 00:00:00

abstract：:The clinical effects of electroconvulsive therapy (ECT) on the morbidity of paranoid schizophrenic patients were assessed by positron emission tomography (PET) and plasma biochemistry studies before and after ECT. The present study included five patients whose average age was 41.4 years. The average duration of illnes...

journal_title：Psychiatry and clinical neurosciences

authors： Uesugi H,Toyoda J,Iio M

更新日期：1995-05-01 00:00:00

abstract：AIMS:Long-term use of methamphetamine could induce psychosis, but consequences with regards to intelligence have seldom been investigated. Long-term use of alcohol could also result in intellectual deterioration. METHODS:The IQ of 34 methamphetamine-induced psychosis (MIP) patients (age, 28.7 +/- 6.1 years) and 34 alc...

journal_title：Psychiatry and clinical neurosciences

authors： Lin SK,Huang MC,Lin HC,Pan CH

更新日期：2010-02-01 00:00:00

abstract：AIM: The aim of this study was to estimate the prevalence of apathy, and to compare vascular mild cognitive impairment (vMCI), amnestic MCI (amMCI), and other type using Clinical Assessment for Spontaneity (CAS). METHODS: Agreement to take part in the study was obtained from 590 community dwellers, aged ≥75 years livi...

journal_title：Psychiatry and clinical neurosciences

authors： Nakamura K,Kasai M,Ouchi Y,Nakatsuka M,Tanaka N,Kato Y,Nakai M,Meguro K

更新日期：2013-11-01 00:00:00

abstract：AIM:Although the association between maternal depression and bonding failure during pregnancy and after delivery has been investigated, the causal relationships remain unclear. METHODS:A total of 751 women (mean [SD] age, 32.1 [4.4] years) completed the Mother-Infant Bonding Questionnaire and the Edinburgh Postnatal D...

journal_title：Psychiatry and clinical neurosciences

authors： Ohara M,Okada T,Kubota C,Nakamura Y,Shiino T,Aleksic B,Morikawa M,Yamauchi A,Uno Y,Murase S,Goto S,Kanai A,Masuda T,Ando M,Ozaki N

更新日期：2017-10-01 00:00:00

abstract：AIM:This paper describes a 1-year follow-up of post-traumatic stress disorder (PTSD) symptomatology and depression in an elderly minority population who experienced Typhoon Morakot in Taiwan. METHODS:The PTSD Symptom Scale--Interview and the 10-item short form Center for Epidemiological Studies Depression Scale were u...

journal_title：Psychiatry and clinical neurosciences

authors： Chen YL,Hsu WY,Lai CS,Tang TC,Wang PW,Yeh YC,Huang MF,Yen CF,Chen CS

更新日期：2015-01-01 00:00:00

abstract：:The validity of two kinds of brief intelligence tests for patients with Alzheimer's disease (AD) was investigated. In study 1, five short forms of the Japanese Wechsler Adult Intelligence Scale-Revised (JWAIS-R) were administered to 102 AD patients. The results showed that the intra-class correlation coefficients (ICC...

journal_title：Psychiatry and clinical neurosciences

authors： Nakamura H,Nakanishi M,Furukawa TA,Hamanaka T,Tokudome S

更新日期：2000-08-01 00:00:00

abstract：:Psychological factors may be associated with the outcome of cancer treatment, including bone marrow transplantation (BMT). However, studies on the issue have provided controversial results. In the present study, effects of mood status on the outcome was studied through a follow-up period of 1-3 years as well as in sho...

journal_title：Psychiatry and clinical neurosciences

authors： Akaho R,Sasaki T,Mori S,Akiyama H,Yoshino M,Hagiya K,Nakagome K,Sakamaki H

更新日期：2003-02-01 00:00:00

abstract：:Granulovacuolar degeneration (GVD) and neurofibrillary tangles (NFT) are neuropathological features in Alzheimer's disease (AD). The molecular mechanism of GVD formation remains unknown. Recent immunohistochemical investigations suggested a potential link of NFT to GVD formation. Enzyme histochemical studies and elect...

journal_title：Psychiatry and clinical neurosciences

authors： Ikegami K,Kimura T,Katsuragi S,Ono T,Yamamoto H,Miyamoto E,Miyakawa T

更新日期：1996-06-01 00:00:00

abstract：:We have introduced behavior therapy as standard in-patient treatment for anorexia nervosa and have modified the treatment program. At first, we used Fukamachi's activity restriction therapy (FT), followed by Token economy therapy (TET), which combined token economy with FT. Finally, we have developed Kyoto Prefectural...

journal_title：Psychiatry and clinical neurosciences

authors： Okamoto A,Yamashita T,Nagoshi Y,Masui Y,Wada Y,Kashima A,Arii I,Nakamura M,Fukui K

更新日期：2002-10-01 00:00:00

abstract：:Issues related to recovery of quality of life (QoL) in depressive outpatients have been raised. This descriptive correlation study investigated QoL in depressive outpatients in Taiwan. A total of 181 depressive outpatients participated in the study. Their QoL levels were measured using the Taiwanese version of the Sho...

journal_title：Psychiatry and clinical neurosciences

authors： Sung SC,Yeh MY

更新日期：2007-12-01 00:00:00

abstract：:Multiple sclerosis (MS) is usually diagnosed on the basis of the typical clinical course, with remission and exacerbation in multiple parts of the central nervous system (CNS). Recently, magnetic resonance imaging (MRI) has made a large contribution to the diagnosis of patients with MS. But it is difficult to make a d...

journal_title：Psychiatry and clinical neurosciences

authors： Ogawa K,Kishi M,Kurihara T,Ikeda K,Kinoshita M

更新日期：1999-08-01 00:00:00

abstract：:We examined the differences between the results of an automatic sleep analysis system and inspection decision. Subjects were 10 males (average age 21.6 years). One section consists of 20 s records. The sections that deviated from the algorithm could not be decided. Each sleep stage decided by automatic analysis was co...

journal_title：Psychiatry and clinical neurosciences

authors： Hashizume Y,Kuwahara H,Uchimura N,Mukai M,Shirakawa S,Satomura T,Takeuchi N,Tanaka J,Maeda H

更新日期：2001-06-01 00:00:00

abstract：AIMS:This 12-week open-label study was designed to investigate the pharmacokinetics and efficacy of a direct switch from a conventional depot to long-acting injectable risperidone in patients with schizophrenia and schizoaffective disorder. METHODS:Men or women from 18 to 65 years old with a diagnosis of schizophrenia...

journal_title：Psychiatry and clinical neurosciences

authors： Lai YC,Huang MC,Chen CH,Tsai CJ,Pan CH,Chiu CC

更新日期：2009-08-01 00:00:00

abstract：AIMS:Fluvoxamine, a selective serotonin reuptake inhibitor, is widely used to treat major depression. However, the symptomatological predictors of the response to fluvoxamine have not been studied. METHODS:This study included 100 Japanese patients who fulfilled the Diagnostic and Statistical Manual of Mental Disorders...

journal_title：Psychiatry and clinical neurosciences

authors： Higuchi H,Sato K,Yoshida K,Takahashi H,Kamata M,Otani K,Yamaguchi N

更新日期：2008-06-01 00:00:00

abstract：:Incidence of serotonin syndrome was determined by two different diagnostic criteria during clomipramine monotherapy. Incidence, determined by Sternbach's criteria, was 12.1% (8/66 patients), and that determined by the criteria of Dursun et al. was 3.0% (2/66 patients). The two patients who met the latter criteria also...

journal_title：Psychiatry and clinical neurosciences

authors： Kudo K,Sasaki I,Tsuchiyama K,Akiyoshi J,Nagayama H,Fujii I

更新日期：1997-02-01 00:00:00

abstract：:Schizotypal personality disorder (SPD) has rarely been reported as an eating disorder-related personality trait. A 23-year-old woman was diagnosed as having anorexia nervosa binge eating/purging type. At the age of 53 years, she was admitted to Jikei University Hospital because of excessive bodyweight loss. She was di...

journal_title：Psychiatry and clinical neurosciences

authors： Nagata T,Ono K,Nakayama K

更新日期：2007-08-01 00:00:00