Surgical treatment of aneurysms of the ascending aorta.

abstract：BACKGROUND:Risk factors for obstructive sleep apnea (OSA) and the development of subsequent cardiovascular (CV) complications differ by sex. We hypothesize that the relationship between OSA and high-sensitivity troponin T (hs-TnT), cardiac structure, and CV outcomes differs by sex. METHODS AND RESULTS:Seven hundred fi...

journal_title：Circulation

authors： Roca GQ,Redline S,Claggett B,Bello N,Ballantyne CM,Solomon SD,Shah AM

更新日期：2015-10-06 00:00:00

abstract：:To assess the results of cardiac repair utilizing a right ventricular to pulmonary artery conduit, we reviewed postoperative hemodynamic data in 16 patients catheterized 0.5 to 5 years after repair. In 12 patients, a Hancock conduit (dacron conduit with porcine valve) was used; the conduit in the remaining four patien...

journal_title：Circulation

authors： Rocchini AP,Rosenthal A,Keane JF,Castaneda AR,Nadas AS

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:During septic shock, the vasoconstrictor response to norepinephrine is seriously blunted. Animal experiments suggest that hyperpolarization of smooth muscle cells by opening of potassium (K) channels underlies this phenomenon. In the present study, we examined whether K-channel blockers and/or nitric oxide (...

journal_title：Circulation

authors： Pickkers P,Dorresteijn MJ,Bouw MP,van der Hoeven JG,Smits P

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Arterial relaxation is largely regulated by endothelial nitric oxide (NO). Its diminished activity has been associated with incipient atherosclerosis. We investigated the endothelium-dependent relaxation of aorta in apolipoprotein E-knockout (apoE-KO) mice exposed to single or repeated Chlamydia pneumoniae i...

journal_title：Circulation

authors： Liuba P,Karnani P,Pesonen E,Paakkari I,Forslid A,Johansson L,Persson K,Wadström T,Laurini R

更新日期：2000-08-29 00:00:00

abstract：:In response to the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, the Chinese Society of Cardiology (CSC) issued this consensus statement after consulting with 125 medical experts in the fields of cardiovascular disease and infectious disease. The over-arching principles laid out here are the followi...

journal_title：Circulation

authors： Han Y,Zeng H,Jiang H,Yang Y,Yuan Z,Cheng X,Jing Z,Liu B,Chen J,Nie S,Zhu J,Li F,Ma C

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:The use of atherosclerotic cardiovascular disease (ASCVD) risk to personalize systolic blood pressure (SBP) treatment goals is a topic of increasing interest. Therefore, we studied whether coronary artery calcium (CAC) can further guide the allocation of anti-hypertensive treatment intensity. METHODS:We inc...

journal_title：Circulation

authors： McEvoy JW,Martin SS,Dardari ZA,Miedema MD,Sandfort V,Yeboah J,Budoff MJ,Goff DC Jr,Psaty BM,Post WS,Nasir K,Blumenthal RS,Blaha MJ

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Catheter-based intrapericardial (IPC) delivery of therapeutic agents has recently been demonstrated. Paclitaxel is known to inhibit vascular smooth muscle cell proliferation. This study examined the effect of IPC instillation of paclitaxel on neointimal proliferation after balloon overstretch of porcine coro...

journal_title：Circulation

authors： Hou D,Rogers PI,Toleikis PM,Hunter W,March KL

更新日期：2000-09-26 00:00:00

abstract：:Diffuse coronary artery disease is frequently untreatable by coronary artery bypass or angioplasty. Many such "no-option" patients have been subjects for trials of angiogenesis using growth factor manipulation or laser injury. We think these novel revascularization strategies are limited by insufficient inflow to puta...

journal_title：Circulation

authors： Oesterle SN,Reifart N,Hauptmann E,Hayase M,Yeung AC

更新日期：2001-05-29 00:00:00

abstract：BACKGROUND:Familial polymorphic ventricular tachycardia is an autosomal-dominant, inherited disease with a relatively early onset and a mortality rate of approximately 30% by the age of 30 years. Phenotypically, it is characterized by salvoes of bidirectional and polymorphic ventricular tachycardias in response to vigo...

journal_title：Circulation

authors： Laitinen PJ,Brown KM,Piippo K,Swan H,Devaney JM,Brahmbhatt B,Donarum EA,Marino M,Tiso N,Viitasalo M,Toivonen L,Stephan DA,Kontula K

更新日期：2001-01-30 00:00:00

abstract：BACKGROUND:Since the atria are thin-walled structures, most studies that have examined the spread of activation in the atria have assumed that they behave electrophysiologically as a two-dimensional surface. It was the objective of this study to determine whether or not this assumption is true by simultaneously mapping...

journal_title：Circulation

authors： Schuessler RB,Kawamoto T,Hand DE,Mitsuno M,Bromberg BI,Cox JL,Boineau JP

更新日期：1993-07-01 00:00:00

abstract：:The purpose of this study was to identify preoperative and intraoperative variables predictive of left ventricular dysfunction 6 months after aortic valve replacement. Patients were considered to have postoperative left ventricular dysfunction if the end-diastolic-volume index was greater than or equal to 101 ml/m2 or...

journal_title：Circulation

authors： Hwang MH,Hammermeister KE,Oprian C,Henderson W,Bousvaros G,Wong M,Miller DC,Folland E,Sethi G

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Although metabolomic profiling offers promise for the prediction of coronary heart disease (CHD), and metabolic risk factors are more strongly associated with CHD in women than men, limited data are available for women. METHODS:We applied a liquid chromatography-tandem mass spectrometry metabolomics platfor...

journal_title：Circulation

authors： Paynter NP,Balasubramanian R,Giulianini F,Wang DD,Tinker LF,Gopal S,Deik AA,Bullock K,Pierce KA,Scott J,Martínez-González MA,Estruch R,Manson JE,Cook NR,Albert CM,Clish CB,Rexrode KM

更新日期：2018-02-20 00:00:00

abstract：:Between January 1, 1970, and December 31, 1974, 2981 patients underwent coronary arteriography. Twelve acute coronary dissections or embolizations occurred, an incidence of 0.4%. The incidences of acute occlusions for the Sones and Judkins techniques were 0.19% (4/2077 studies) and 0.88% (8/940), respectively. No inst...

journal_title：Circulation

authors： Guss SB,Zir LM,Garrison HB,Daggett WM,Block PC,Dinsmore RE

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Conventional x-ray angiography frequently underestimates the true burden of atherosclerosis. Although intravascular ultrasound allows for imaging of coronary plaque, this invasive technique is inappropriate for screening or serial examinations. We therefore sought to develop a noninvasive free-breathing MR t...

journal_title：Circulation

authors： Botnar RM,Stuber M,Kissinger KV,Kim WY,Spuentrup E,Manning WJ

更新日期：2000-11-21 00:00:00

abstract：BACKGROUND:Fibrosis and progressive failure are prominent pathophysiological features of hearts after myocardial infarction (MI). We examined the effects of inhibiting transforming growth factor-beta (TGF-beta) signaling on post-MI cardiac fibrosis and ventricular remodeling and function. METHODS AND RESULTS:MI was in...

journal_title：Circulation

authors： Okada H,Takemura G,Kosai K,Li Y,Takahashi T,Esaki M,Yuge K,Miyata S,Maruyama R,Mikami A,Minatoguchi S,Fujiwara T,Fujiwara H

更新日期：2005-05-17 00:00:00

abstract：BACKGROUND:CXCL16/SR-PSOX is an interferon-gamma-regulated chemokine and scavenger receptor for oxidized low-density lipoprotein that is expressed in atherosclerotic lesions. Proteolytic cleavage of membrane-bound CXCL16 releases soluble CXCL16, which may promote migration of effector T cells and augment a proatherogen...

journal_title：Circulation

authors： Jansson AM,Aukrust P,Ueland T,Smith C,Omland T,Hartford M,Caidahl K

更新日期：2009-06-30 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) and angiotensin II (Ang II) modulate heart failure in part by provoking the hypertrophic response. Signal transduction pathways of those factors are implicated in reactive oxygen intermediates (ROIs). Therefore, we hypothesized that TNF-alpha and Ang II might cause myo...

journal_title：Circulation

authors： Nakamura K,Fushimi K,Kouchi H,Mihara K,Miyazaki M,Ohe T,Namba M

更新日期：1998-08-25 00:00:00

abstract：BACKGROUND:Reperfusion of acutely infarcted myocardium may be beneficial in limiting infarct expansion and ventricular remodeling even if established after the time that salvage of ischemic myocardium is possible. METHODS AND RESULTS:To examine the permanency, time course, and mechanism of this effect of late reperfus...

journal_title：Circulation

authors： Boyle MP,Weisman HF

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Cystic kidneys and vascular aneurysms are clinical manifestations seen in patients with polycystic kidney disease, a cilia-associated pathology (ciliopathy). Survivin overexpression is associated with cancer, but the clinical pathology associated with survivin downregulation or knockout has never been studie...

journal_title：Circulation

authors： Aboualaiwi WA,Muntean BS,Ratnam S,Joe B,Liu L,Booth RL,Rodriguez I,Herbert BS,Bacallao RL,Fruttiger M,Mak TW,Zhou J,Nauli SM

更新日期：2014-02-11 00:00:00

abstract：:Electrocardiograms from 5,129 examined persons, 2,449 men and 2,680 women, 16 years of age or older, were classified according to the Minnesota code of Blackburn and associates. The R wave amplitude criteria for possible left ventricular hypertrophy were fulfilled in 193 tracings from 135 men and 58 women. Age and sex...

journal_title：Circulation

authors： Ostrander LD Jr

更新日期：1966-02-01 00:00:00

abstract：BACKGROUND:Erosion and rupture of coronary atheromas are the events preceding the vast majority of acute coronary syndromes. The shoulder regions of atheromas, the sites at which erosion or rupture is most likely to occur, are the sites at which mast cells accumulate. These cells are filled with neutral proteases capab...

journal_title：Circulation

authors： Kovanen PT,Kaartinen M,Paavonen T

更新日期：1995-09-01 00:00:00

abstract：:Normal right ventricular muscles and similar preparations obtained from cats with signs of subacute right ventricular failure (RVF) (3 to 14 days after pressure overload induced by pulmonary artery coarctation) were studied during stimulation (at 0.5 Hz) and exposure to high-K+ Tyrode's solution. Twitch force, rate of...

journal_title：Circulation

authors： Gaide MS,Kimura S,Lodge NJ,Cameron JS,Kozlovskis PL,Myerburg RJ,Bassett AL

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Cardiovascular events are less prevalent in premenopausal women and women receiving estrogen replacement than in postmenopausal women or men. Endothelium-derived relaxing factor (EDRF) is an important local modulator of vascular tone, and abnormal endothelial function is related, in part, to the oxidative mo...

journal_title：Circulation

authors： Keaney JF Jr,Shwaery GT,Xu A,Nicolosi RJ,Loscalzo J,Foxall TL,Vita JA

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Marine n-3 polyunsaturated fatty acids may reduce coronary mortality. Previous data in relation to nonfatal coronary disease, however, have been inconsistent, which may be explained by the use of heterogeneous methods to assess the intake of marine n-3 polyunsaturated fatty acids. We investigated the hypothe...

journal_title：Circulation

authors： Joensen AM,Overvad K,Dethlefsen C,Johnsen SP,Tjønneland A,Rasmussen LH,Schmidt EB

更新日期：2011-09-13 00:00:00

abstract：BACKGROUND:Recent findings suggesting the involvement of adventitial cells in coronary repair have raised questions regarding the phenotypic "plasticity" of medial smooth muscle cells (SMCs). Accordingly, the aims of the present study were to examine the characteristics of coronary medial and adventitial cells and to c...

journal_title：Circulation

authors： Patel S,Shi Y,Niculescu R,Chung EH,Martin JL,Zalewski A

更新日期：2000-02-08 00:00:00

abstract：BACKGROUND:Chemokines are important mediators of inflammatory cell recruitment that play a significant role in atherosclerosis. Fractalkine (CX3CL1) is an unusual membrane-bound chemokine that mediates chemotaxis through the CX3CR1 receptor. Recently, functional polymorphisms in the human CX3CR1 gene have been describe...

journal_title：Circulation

authors： Lucas AD,Bursill C,Guzik TJ,Sadowski J,Channon KM,Greaves DR

更新日期：2003-11-18 00:00:00

abstract：BACKGROUND:Functional mitral regurgitation (MR) is common in patients with heart failure and left ventricular (LV) dysfunction, and its severity may vary over time, depending primarily on the loading conditions. Because dynamic changes in the severity of functional MR may affect forward stroke volume, we hypothesized t...

journal_title：Circulation

authors： Lapu-Bula R,Robert A,Van Craeynest D,D'Hondt AM,Gerber BL,Pasquet A,Melin JA,De Kock M,Vanoverschelde JL

更新日期：2002-09-10 00:00:00

abstract：BACKGROUND:Early defibrillation is the most important intervention affecting survival from sudden cardiac arrest (SCA). To improve public access to early defibrillation, we established Piacenza Progetto Vita (PPV), the first system of out-of-hospital early defibrillation by first-responder volunteers. METHODS AND RESU...

journal_title：Circulation

authors： Capucci A,Aschieri D,Piepoli MF,Bardy GH,Iconomu E,Arvedi M

更新日期：2002-08-27 00:00:00

abstract：BACKGROUND:Lead V(1) directly faces the right ventricle and may exhibit ST elevation during an acute inferior myocardial infarction when the right ventricle is also involved. Leads V(1) and V(3) indirectly face the posterolateral left ventricle, and ST depression ("mirror-image" ST elevation) in V(1) through V(3) may r...

journal_title：Circulation

authors： Wong CK,Gao W,Stewart RA,French JK,Aylward PE,Benatar J,White HD,Hirulog and Early Reperfusion or Occlusion-2 Investigators.

更新日期：2010-08-03 00:00:00

abstract：:Esophageal perforation is a dreaded complication of atrial fibrillation ablation that occurs in 0.1% to 0.25% of atrial fibrillation ablation procedures. Delayed diagnosis is associated with the development of atrial-esophageal fistula (AEF) and increased mortality. The relationship between the esophagus and the left ...

journal_title：Circulation

authors： Kapur S,Barbhaiya C,Deneke T,Michaud GF

更新日期：2017-09-26 00:00:00