Abstract：
OBJECTIVE:There are divergent opinions about the prognostic value of the extent of surgery and of different histological subtypes in supratentorial astrocytomas WHO grade II. METHODS:We reviewed 75 consecutive patients (36 females, 39 males) with supratentorial astrocytomas WHO grade II (59 primary and 16 recurrent tumours) operated on between 1991 and 1995. RESULTS:Gross total resection could be achieved in 40 astrocytomas, subtotal resection (including biopsy) was performed in 35 cases. Histological assessment confirmed 60 fibrillary, 6 gemistocytic, 9 oligo-astrocytic and no protoplasmic astrocytomas. There were no postoperative deaths. Early outcome 6 to 12 weeks after surgery according to the Glasgow Outcome Scale was good in 46 patients, 24 patients had moderate, and 5 had severe neurological deficits. Survival rates 1, 2, 3, and 4 years following surgery were 100%, 96%, 96%, 96% for patients who underwent gross total tumour resection and 86%, 77%, 77%, 64% for patients with subtotal tumour resection. The cumulative recurrence or progression rates after 4 years were 26% after gross total resection and 80% after subtotal resection, and this result is statistically significant. Recurrences after gross total resection or progressions after subtotal resection occurred more often in gemistocytic astrocytomas (40% and 100%, respectively) than in other subtypes. Dedifferentiation to a more malignant tumour seems to be more prominent in the gemistocytic subtype. CONCLUSION:Gross total resection should be the leading therapeutic option for patients with astrocytomas WHO grade II. For the gemistocytic subtype further studies will have to prove whether additional radiotherapy is of any benefit.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Peraud A,Ansari H,Bise K,Reulen HJdoi
10.1007/s007010050241subject
Has Abstractpub_date
1998-01-01 00:00:00pages
1213-22issue
12eissn
0001-6268issn
0942-0940journal_volume
140pub_type
杂志文章abstract：:The electromagnetic field focusing (EFF) probe is capable of producing well circumscribed, intense heat at the point of contact with the tissue. Experimental studies were carried out to assess this probe as a neurosurgical tool using 38 rats and 4 mice with mammary carcinoma. The study on the rats included study of th...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01402293
更新日期：1987-01-01 00:00:00
abstract：:Does the absolute value of the stump pressure (post-occlusion back pressure) become a useful index of a good collateral circulation? The authors continuously monitored the mean arterial pressure before, during and after 20-minute balloon test occlusion in 24 patients. The stump pressure was then compared with the resu...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01411175
更新日期：1996-01-01 00:00:00
abstract：:Regression of meningioma after haemorrhage and the cessation of hormone treatment is well reported. However, spontaneous regression is very rarely observed. Here, we report the spontaneous regression of a parafalcine meningioma in a 56-year-old woman with multiple sclerosis, who was referred to our department after an...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-016-3019-6
更新日期：2017-03-01 00:00:00
abstract：:Changes in vestibulospinal evoked potentials (VsEP) and motor evoked potentials (MEP) were examined in 10 cats before and after two different weight-dropping spinal cord injuries. In six animals somatosensory evoked potentials (SEP) were also monitored. The recordings were done from epidural spinal cord electrodes. Be...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01410530
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Most surgical teams currently consider that endoscopy has become the "gold standard" technique for the transsphenoidal approach to pituitary surgery. Pituitary adenomas are commonly benign tumours and should benefit from the least invasive approach. METHOD:In Foch Hospital, from 2006 to 2020, 2835 patients ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-020-04542-z
更新日期：2020-08-29 00:00:00
abstract：BACKGROUND:To evaluate the clinical presentation, diagnostic and therapeutic management and outcome of 27 cases of post-traumatic thoracic outlet syndrome (PT TOS). METHODS:Retrospective chart analysis. RESULTS:Nineteen women and eight men were included in this study. Involvement in a traffic accident was the most co...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-011-1269-x
更新日期：2012-03-01 00:00:00
abstract：:The findings of computerized tomography and clinical features were studied in 19 patients with traumatic intraventricular haemorrhage. Blood was found in various portion of the ventricles. Main sites of the blood was as follows: around the foramen of Monro, 6 patients; in the body and occipital horn of the lateral ven...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01404144
更新日期：1987-01-01 00:00:00
abstract：:Renal cell carcinoma has a complex and variable natural history. We report a case underlining this who presented concomitant renal cell carcinoma metastasis with pituitary and adrenocortical adenomas. A 62-year-old woman presented with visual loss. Imaging revealed a large sellar mass with suprasellar extension. Four ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-002-1060-0
更新日期：2003-03-01 00:00:00
abstract：BACKGROUND:Within the realm of neurosurgery, petroclival meningiomas are regarded as probably the most difficult tumour to be treated by microsurgery. This is due to the not infrequently large size of the tumours which, although predominantly located in the posterior fossa, may occupy more than one cranial compartment,...
journal_title：Acta neurochirurgica
pub_type： 历史文章,杂志文章
doi：10.1007/s00701-010-0633-6
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Paragangliomas are tumors that arise from the paraganglion system, which is a component of the neuroendocrine system. Approximately 10% are located in the extra-adrenal paraganglion system. Paragangliomas of the spine, however, are rare. They usually present as an intradural tumor in the cauda equina. There ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-009-0362-x
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:To investigate whether patients with critical emergency conditions are seeking or receiving the medical care that they require, we characterized the reality of care for patients presenting with neuro-emergencies during the first phase of the COVID-19 pandemic. METHODS:In this observational, longitudinal coh...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-020-04437-z
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:To investigate the natural history and the growth rate of spheno-orbital meningiomas (SOMs). METHODS:Ninety patients with a diagnosis of SOM were included, and patient charts and imaging were evaluated. In a subset of 32 patients, volumetric studies were performed. RESULTS:The median follow-up for the enti...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-010-0878-0
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Drain insertion following chronic subdural haematoma (CSDH) evacuation reduces recurrence and improves outcomes. The mechanism of this improvement is uncertain. We assessed whether drains result in improved postoperative imaging, and which radiological factors are associated with recurrence and functional ou...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,多中心研究
doi：10.1007/s00701-020-04356-z
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Although 30-50 % of patients with brain tumors experience epileptic seizure as the presenting clinical symptom, and another 10-30 % are at risk for developing epilepsy in the later stages of the disease, the mechanisms of tumor-related epileptogenesis are poorly understood. We used magnetoencephalography (ME...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1781-2
更新日期：2013-08-01 00:00:00
abstract：:The characteristic findings of metrizamide CT cisternography in two cases of epidermoid are reported. The main finding was a "cauliflower-like" appearance and was thought to be caused by the irregular interstices of epidermoids. Metrizamide CT cisternography may be helpful in making a diagnosis of an epidermoid. ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01400854
更新日期：1984-01-01 00:00:00
abstract：BACKGROUND:To determine its roles in the diagnosis and the systemic evaluation of metastatic brain tumours, whole-body positron emission tomography (PET) using [18F]FDG was performed in 20 consecutive patients. METHODS:All patients were thought to be suffering or needing to be differentiated from metastatic brain tumo...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s007010050161
更新日期：1998-01-01 00:00:00
abstract：AIM:Numerous materials have been used to replace defects in the dura mater as result of neurosurgical and spinal procedures. Tissudura is a biomatrix made of cross-linked equine collagen fibrils, mainly of the interstitial type I. The specially engineered dura-like layered structure provides a non porous primary water ...
journal_title：Acta neurochirurgica
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/s00701-009-0290-9
更新日期：2009-05-01 00:00:00
abstract：:Migration of the catheter tip of a ventriculoperitoneal shunt (VPS) through a patent processus vaginalis (PV) has seldom being reported. In this series, we analyzed all cases of inguinoscrotal migration of an VPS catheter at our center. Between 1975 and 2015, 295 VPS insertions were performed. In seven infants (2.3%),...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-017-3243-8
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:To present the combined treatment of fusiform basilar artery aneurysms consisting of a surgical posterior fossa decompressive craniectomy and ventriculoperitoneal (VP) shunt operation at the same sitting, before the endovascular procedure with telescopic stenting of the aneurysmatic vessel segment in four ca...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1913-8
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Side-to-side neurorrhaphy may protect the denervated end organ and preserve the initial connection with proximal stump. We examined the effect of protective side-to-side anastomosis on nerve and end organ regeneration in proximal nerve injury model. METHODS:The left common peroneal nerve of 24 Sprague Dawle...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-019-03835-2
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Multiple intracranial aneurysms (MIAs) are associated with poorer outcomes after rupture than are single intracranial aneurysms (SIAs). Although the risk factors for intracranial aneurysm rupture have been widely investigated, few studies have focused on MIAs. Thus, the present study aimed to determine wheth...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-016-2826-0
更新日期：2016-07-01 00:00:00
abstract：:An infrared based frameless stereotactic navigation device (Easy Guide Neuro) was investigated for its clinical applicability, registration/application accuracy and limitations in a standard operating room set-up. In a five-month period 40 frameless stereotactic procedures (23 female, 17 male, mean age 46.4, yrs range...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF02750999
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Data regarding long-term outcomes following surgery for cauda equina syndrome (CES) is scarce. In addition, these studies rely on patient descriptions of the presence or absence of symptoms, with no gradation of severity. This study aimed to assess long-term bladder, bowel, sexual and physical function using...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-019-03973-7
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Several studies have included different co-morbid conditions in prediction models for stroke patients. For subarachnoid haemorrhage (SAH), it is not known whether the Charlson Co-morbidity Index (CCI) is associated with outcome. We evaluated if this index was associated with outcome in patients with ruptured...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-014-2160-3
更新日期：2014-09-01 00:00:00
abstract：:Recent animal research has provided evidence that brain ischaemia is associated with a shift of energy related metabolites (lactate, adenosine, inosine, and hypoxanthine) and several transmitters from the intracellular to the extracellular fluid (ECF). These chemical changes of the ECF reflect the energy crisis of the...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01405420
更新日期：1990-01-01 00:00:00
abstract：:An uncommon cause of progressive dysphagia may be large cervical osteophytes impinging upon the cervical esophagus. Dysphagia may be due to the mechanical mass effect of a large anterior osteophyte, trapping the esophagus opposite a fixed point such as the cricoid cartilage, or a local inflammatory reaction resulting ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01410071
更新日期：1989-01-01 00:00:00
abstract：:Ventriculo-subgaleal shunting was used for temporary decompression of hypertensive hydrocephalus. Pre- and post-shunt computed tomography was utilized in five cases as a method for detecting complications and determining shunt function. A clear-cut clinical improvement and stabilization followed the subgaleal diversio...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01808925
更新日期：1980-01-01 00:00:00
abstract：:Diffuse brain injury in rabbits was caused by injecting olive oil and saline into one internal carotid artery. In this report, the fourth of a series, the effects of this experimental brain injury on respiration and acid-base balance of blood are analyzed. The animals that withstood the injury best were those that had...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01405898
更新日期：1975-01-01 00:00:00
abstract：BACKGROUND:The scientific activity of neurosurgeons and neurosurgery residents as measured by bibliometric parameters is of increased interest. While data about academic output for neurosurgeons in the USA, the UK, and Canada have been published, no similar results for German neurosurgical residents exist. Within this ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-019-04011-2
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Implantation of neural cells has been proposed as a therapeutic strategy for repairing the injured or diseased brain. In the present study we have examined the potential of olfactory ensheathing cells (OEC) to promote brain repair after surgical implantation in a rodent model of parkinsonism. METHODS:Neonat...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-007-1121-5
更新日期：2007-01-01 00:00:00
