Prospective temporal analysis of the onset of preinfarction angina versus outcome: an ancillary study in TIMI-9B.

abstract：BACKGROUND:Ezetimibe, when added to simvastatin, reduces cardiovascular events after acute coronary syndrome. We explored outcomes stratified by diabetes mellitus (DM). METHODS:In IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial), 18 144 patients after acute coronary syndrome with low-d...

journal_title：Circulation

authors： Giugliano RP,Cannon CP,Blazing MA,Nicolau JC,Corbalán R,Špinar J,Park JG,White JA,Bohula EA,Braunwald E,IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial) Investigators.

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:High-speed rotational atherectomy uses a diamond-coated, elliptical burr to abrade occlusive atherosclerosis, especially noncompliant calcified plaque. METHODS AND RESULTS:Intravascular ultrasound (IVUS) was used to analyze 28 patients after atherectomy. Arteries treated and imaged were left main (three), l...

journal_title：Circulation

authors： Mintz GS,Potkin BN,Keren G,Satler LF,Pichard AD,Kent KM,Popma JJ,Leon MB

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Vasoactive drugs could alter the fluid restitution from the tissue and redistribute blood volume between the macrocirculation and microcirculation. METHODS AND RESULTS:With bolus injections of vasoactive drugs in anesthetized rabbits, we measured the changes in blood and plasma density for the determination...

journal_title：Circulation

authors： Anderson SM,Rich GF,Roos C,Lee LP,Lee JS

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Transcatheter aortic valve replacement (TAVR) represents a paradigm shift in the therapeutic options for patients with severe aortic stenosis. However, rapid and exponential growth in TAVR demand may overwhelm capacity, translating to inadequate access and prolonged wait times. Our objective was to evaluate ...

journal_title：Circulation

authors： Elbaz-Greener G,Masih S,Fang J,Ko DT,Lauck SB,Webb JG,Nallamothu BK,Wijeysundera HC

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Sublingual nitrates are much more effective in relieving angina pectoris in patients with coronary artery disease than in patients with syndrome X, but it is not known whether their effect on exercise tolerance is also different in these two groups of patients. METHODS AND RESULTS:Treadmill exercise testing...

journal_title：Circulation

authors： Lanza GA,Manzoli A,Bia E,Crea F,Maseri A

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Little information is available regarding the occurrence of perioperative and late cardiac events in women with vascular disease. The current study was performed to examine whether sex-specific differences exist in these outcomes in a large population of vascular surgery patients and to determine the value o...

journal_title：Circulation

authors： Hendel RC,Chen MH,L'Italien GJ,Newell JB,Paul SD,Eagle KA,Leppo JA

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:To further evaluate the mechanism of beta-blocker-induced benefits in heart failure, the relationships between bisoprolol-induced hemodynamic effects and survival were studied during the Cardiac Insufficiency BIsoprolol Study (CIBIS). METHODS AND RESULTS:In 557 patients studied, bisoprolol significantly red...

journal_title：Circulation

authors： Lechat P,Escolano S,Golmard JL,Lardoux H,Witchitz S,Henneman JA,Maisch B,Hetzel M,Jaillon P,Boissel JP,Mallet A

更新日期：1997-10-07 00:00:00

abstract：BACKGROUND:Magnetic resonance (MR) phase-shift velocity mapping is an established method for measurement of nonturbulent intravascular flow. Shortening the echo time of the MR sequence to 3.6 msec allowed application of the technique to turbulent jet flow. The objective of this study was validation of MR jet velocity m...

journal_title：Circulation

authors： Kilner PJ,Manzara CC,Mohiaddin RH,Pennell DJ,Sutton MG,Firmin DN,Underwood SR,Longmore DB

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:A completed Fontan circulation is the goal in the management of patients with single-ventricle physiology. To achieve this end, a two-stage rather than a single-stage approach is carried out routinely at many centers. Some groups have advocated baffle fenestration for virtually all patients to minimize post-...

journal_title：Circulation

authors： Hsu DT,Quaegebeur JM,Ing FF,Selber EJ,Lamour JM,Gersony WM

更新日期：1997-11-04 00:00:00

abstract：:Exercise trials in cardiology are often hindered by inconsistent approaches to exercise testing. These inconsistencies include the choice of exercise protocol, exercise end points, points of analysis, and absence or misuse of gas exchange data. Gas exchange techniques greatly enhance the accuracy with which cardiopulm...

journal_title：Circulation

authors： Myers J,Froelicher VF

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Inhaled nitric oxide (NO) is a potent and selective pulmonary vasodilator, which induces cGMP synthesis by activating soluble guanylate cyclase (sGC) in ventilated lung regions. Carbon monoxide (CO) has also been proposed to influence smooth muscle tone via activation of sGC. We examined whether direct stimu...

journal_title：Circulation

authors： Evgenov OV,Ichinose F,Evgenov NV,Gnoth MJ,Falkowski GE,Chang Y,Bloch KD,Zapol WM

更新日期：2004-10-12 00:00:00

abstract：BACKGROUND:Anisotropic conduction properties may provide a substrate for reentrant arrhythmias. We investigated the age-dependent changes of structural and functional anisotropy in isolated right atria from infant (1 to 2 months), young (6 to 12 months), and old (6 to 10 years) dogs. METHODS AND RESULTS:The histology ...

journal_title：Circulation

authors： Koura T,Hara M,Takeuchi S,Ota K,Okada Y,Miyoshi S,Watanabe A,Shiraiwa K,Mitamura H,Kodama I,Ogawa S

更新日期：2002-04-30 00:00:00

abstract：:A 10 mg bolus of the angiotensin blocker saralasin was injected 113 times in 68 subjects with essential or renovascular hypertension. Ninety percent of injections caused a transient increase in blood pressure, which correlated with plasma renin activity (PRA) (r = -0.54); Mean increase at 2 minutes was 21/13.4 mm Hg (...

journal_title：Circulation

authors： Waks UA,Maxwell MH,Marks L,Zawada ET,Kaufman JJ

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:Apoptosis contributes to cell loss after ischemia/reperfusion injury in the heart. This study describes the time course and level of apoptosis in different cell types in the intact heart during ischemia/reperfusion injury. METHODS AND RESULTS:Isolated Langendorff-perfused rat hearts were subjected to perfus...

journal_title：Circulation

authors： Scarabelli T,Stephanou A,Rayment N,Pasini E,Comini L,Curello S,Ferrari R,Knight R,Latchman D

更新日期：2001-07-17 00:00:00

abstract：:To assess the results of cardiac repair utilizing a right ventricular to pulmonary artery conduit, we reviewed postoperative hemodynamic data in 16 patients catheterized 0.5 to 5 years after repair. In 12 patients, a Hancock conduit (dacron conduit with porcine valve) was used; the conduit in the remaining four patien...

journal_title：Circulation

authors： Rocchini AP,Rosenthal A,Keane JF,Castaneda AR,Nadas AS

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Body fat distribution has been cross-sectionally associated with atherosclerotic disease risk factors, but the prospective relation with coronary heart disease remains uncertain. METHODS AND RESULTS:We examined the prospective relation between fat distribution indices and coronary heart disease among 24,508...

journal_title：Circulation

authors： Canoy D,Boekholdt SM,Wareham N,Luben R,Welch A,Bingham S,Buchan I,Day N,Khaw KT

更新日期：2007-12-18 00:00:00

abstract：:Continuous-wave Doppler echocardiography was used to estimate pulmonary artery pressures by measuring pulmonary regurgitant flow velocity in 21 patients with pulmonary hypertension (mean pulmonary artery pressure greater than or equal to 20 mm Hg) and 24 patients without pulmonary hypertension. The pulmonary regurgita...

journal_title：Circulation

authors： Masuyama T,Kodama K,Kitabatake A,Sato H,Nanto S,Inoue M

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:We previously found in a pig coronary balloon injury model that vitamins C and E as well as probucol had beneficial effects on the vessel response to injury measured by morphometry These effects correlated with an inhibition in the ability to oxidize LDLs ex vivo, suggesting that the morphological response w...

journal_title：Circulation

authors： Nunes GL,Robinson K,Kalynych A,King SB 3rd,Sgoutas DS,Berk BC

更新日期：1997-11-18 00:00:00

abstract：BACKGROUND:Optimal management of acute pulmonary embolism (PE) requires medical expertise, diagnostic testing, and therapies that may not be available consistently throughout the entire week. We sought to assess whether associations exist between weekday or weekend admission and mortality and length of hospital stay fo...

journal_title：Circulation

authors： Aujesky D,Jiménez D,Mor MK,Geng M,Fine MJ,Ibrahim SA

更新日期：2009-02-24 00:00:00

abstract：BACKGROUND:Recently, it was shown that intraindividual variation in low-density lipoprotein cholesterol (LDL-C) predicts both cerebrovascular and cardiovascular events. We aimed to examine whether this extends to cognitive function and examined possible pathways using a magnetic resonance imaging substudy. METHODS:We ...

journal_title：Circulation

authors： Smit RA,Trompet S,Sabayan B,le Cessie S,van der Grond J,van Buchem MA,de Craen AJ,Jukema JW

更新日期：2016-07-19 00:00:00

abstract：BACKGROUND:Two hundred eighteen patients were evaluated in a two-phase approach (time to first appropriate discharge, survival after discharge) to identify factors that may be related to maximal benefit derived from use of an automatic implantable cardioverter-defibrillator (AICD). METHODS AND RESULTS:One hundred nine...

journal_title：Circulation

authors： Levine JH,Mellits ED,Baumgardner RA,Veltri EP,Mower M,Grunwald L,Guarnieri T,Aarons D,Griffith LS

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Increased activity of the sympathetic nervous system contributes significantly to the pathophysiology of heart failure. However, cardiac efferent sympathetic function has not been well characterized in this disorder. In this study, we evaluated cardiac sympathetic innervation using [123I]metaiodobenzylguanid...

journal_title：Circulation

authors： Simmons WW,Freeman MR,Grima EA,Hsia TW,Armstrong PW

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:This multicenter trial was conducted to determine the efficacy and safety of pimobendan, an inotropic agent with calcium-sensitizing properties and activity as a phosphodiesterase inhibitor, in patients with heart failure. METHODS AND RESULTS:One hundred ninety-eight ambulatory patients with symptoms of mod...

journal_title：Circulation

authors： Kubo SH,Gollub S,Bourge R,Rahko P,Cobb F,Jessup M,Brozena S,Brodsky M,Kirlin P,Shanes J

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:The degree of protection provided to the right ventricle during retrograde continuous normothermic blood cardioplegia (RCNBC) remains controversial. The purpose of this study was to determine whether RCNBC is able to provide "adequate" nutritive flow to both ventricles to prevent ischemic metabolism in norma...

journal_title：Circulation

authors： Ye J,Sun J,Shen J,Gregorash L,Summers R,Salerno TA,Deslauriers R

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:Pulmonary vein (PV) -encircling radiofrequency ablation frequently is effective in vagal atrial fibrillation (AF), and there is evidence that PVs may be particularly prone to cholinergically induced arrhythmia mechanisms. However, PV ablation procedures also can affect intracardiac autonomic ganglia. The pre...

journal_title：Circulation

authors： Lemola K,Chartier D,Yeh YH,Dubuc M,Cartier R,Armour A,Ting M,Sakabe M,Shiroshita-Takeshita A,Comtois P,Nattel S

更新日期：2008-01-29 00:00:00

abstract：BACKGROUND:Advances in surgical technique and perioperative myocardial protection have reduced the risk of aortic and mitral valve surgery. Improved methods of valve repair have reduced the proportion of patients who require valve replacement. However, patients who require valve replacement often have advanced disease ...

journal_title：Circulation

authors： Rao V,Christakis GT,Weisel RD,Buth KJ,Ikonomidis JS,Shirai T,Cohen G,David TE

更新日期：1996-11-01 00:00:00

abstract：:Three patients with total anomalous pulmonary venous drainage (TAPVD) into the innominate vein were studied by using M-mode and pulsed Doppler echocardiography. An abnormal continuous flow towards the transducer in a suprasternal notch position detected by pulsed Doppler echocardiography in the left hemithorax leftwar...

journal_title：Circulation

authors： Skovránek J,Tůma S,Urbancová D,Samánek M

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:There is no published randomized study comparing amiodarone therapy and radiofrequency catheter ablation (RFA) after only 1 episode of symptomatic atrial flutter (AFL). The aim of the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) Trial of Atrial Flutter was 2-fold: (1) to prospectively compare first-line RFA...

journal_title：Circulation

authors： Da Costa A,Thévenin J,Roche F,Romeyer-Bouchard C,Abdellaoui L,Messier M,Denis L,Faure E,Gonthier R,Kruszynski G,Pages JM,Bonijoly S,Lamaison D,Defaye P,Barthélemy JC,Gouttard T,Isaaz K,Loire-Ardèche-Drôme-Isère-Puy-de-D

更新日期：2006-10-17 00:00:00

abstract：BACKGROUND:This study reports on the trends in the volume and outcomes of coronary revascularization procedures performed on Medicare beneficiaries between 2008 and 2012. METHODS AND RESULTS:This retrospective study identifies all Medicare beneficiaries undergoing a coronary revascularization procedure: coronary arter...

journal_title：Circulation

authors： Culler SD,Kugelmass AD,Brown PP,Reynolds MR,Simon AW

更新日期：2015-01-27 00:00:00

abstract：BACKGROUND:In individuals without known cardiovascular disease, elevated body mass index (BMI) (weight/height2) is associated with an increased risk of death. However, in patients with certain specific chronic diseases, including heart failure, low BMI has been associated with increased mortality. METHODS AND RESULTS:...

journal_title：Circulation

authors： Kenchaiah S,Pocock SJ,Wang D,Finn PV,Zornoff LA,Skali H,Pfeffer MA,Yusuf S,Swedberg K,Michelson EL,Granger CB,McMurray JJ,Solomon SD,CHARM Investigators.

更新日期：2007-08-07 00:00:00