Host immune responses to ribosome, ribosomal proteins, and RNA from Mycobacterium bovis bacille de Calmette-Gúerin.

abstract：:Over the last ten years, Chikungunya virus (CHIKV), an Old World alphavirus has caused numerous outbreaks in Asian and European countries and the Americas, making it an emerging pathogen of great global health importance. Venezuelan equine encephalitis virus (VEEV), a New World alphavirus, on the other hand, has been ...

journal_title：Vaccine

authors： Gayen M,Gupta P,Morazzani EM,Gaidamakova EK,Knollmann-Ritschel B,Daly MJ,Glass PJ,Maheshwari RK

更新日期：2017-06-22 00:00:00

abstract：INTRODUCTION:The recent emergence of avian influenza strains has fuelled concern about pandemic preparedness since vaccines targeting these viruses are often poorly immunogenic. Weak antibody responses to vaccines have been seen across multiple platforms including plant-made VLPs. To better understand these differences...

journal_title：Vaccine

authors： Hendin HE,Pillet S,Lara AN,Wu CY,Charland N,Landry N,Ward BJ

更新日期：2017-05-02 00:00:00

abstract：:Immune responses to human rotaviruses were investigated in sheep with a view to obtaining antibodies for passive immunotherapy of humans. Eighteen adult sheep with previous natural exposure to rotavirus serotypes G3 and G6 were immunized parenterally with purified preparations of either individual rotavirus serotypes ...

journal_title：Vaccine

authors： Beards GM,King JA,Mazhar S,Landon J,Desselberger U

更新日期：1993-01-01 00:00:00

abstract：:Mice inoculated intranasally (i.n.) with a recombinant strain of live Lactococcus lactis expressing tetanus toxin fragment C (TTFC), produced both serum and secretory antibodies to TTFC. Killed bacteria which had accumulated TTFC intracellularly in vitro also elicited protective serum antibody responses. There was no ...

journal_title：Vaccine

authors： Norton PM,Wells JM,Brown HW,Macpherson AM,Le Page RW

更新日期：1997-04-01 00:00:00

abstract：:The vast majority of women infected with human immunodeficiency virus (HIV) will be co-infected with human papillomavirus (HPV). The interaction between the two sexually transmitted infections appears to be related to the alteration in cell-mediated immunity in HIV infected persons, increased susceptibility, and possi...

journal_title：Vaccine

authors： Denny LA,Franceschi S,de Sanjosé S,Heard I,Moscicki AB,Palefsky J

更新日期：2012-11-20 00:00:00

abstract：:The oral, pentavalent rotavirus vaccine (PRV), RotaTeq was assessed for prevention of severe rotavirus gastroenteritis (RVGE) in young children in two multi-site, randomized, placebo-controlled field trials; one in Asia (Vietnam and Bangladesh) and the other in sub-Saharan Africa (Ghana, Kenya and Mali). The efficacy ...

journal_title：Vaccine

authors： Sow SO,Tapia M,Haidara FC,Ciarlet M,Diallo F,Kodio M,Doumbia M,Dembélé RD,Traoré O,Onwuchekwa UU,Lewis KD,Victor JC,Steele AD,Neuzil KM,Kotloff KL,Levine MM

更新日期：2012-04-27 00:00:00

abstract：:While the large majority of parents in the U.S. vaccinate their children according to the recommended immunization schedule, some parents have refused or delayed vaccinating, often citing safety concerns. In response to public concern, the U.S. Institute of Medicine (IOM) evaluated existing research regarding the safe...

journal_title：Vaccine

authors： Glanz JM,Newcomer SR,Jackson ML,Omer SB,Bednarczyk RA,Shoup JA,DeStefano F,Daley MF

更新日期：2016-02-15 00:00:00

abstract：:Sindbis replicon-based vaccine vectors are designed to combine the immunostimulatory properties of replicating viruses with the superior safety profile of non-replicating systems. In this study we performed a detailed assessment of Sindbis (SIN) replicon vectors expressing HIV-1 envelope protein (Env) for the inductio...

journal_title：Vaccine

authors： Center RJ,Miller A,Wheatley AK,Campbell SM,Siebentritt C,Purcell DF

更新日期：2013-04-26 00:00:00

abstract：:The Vaccine Adverse Event Reporting System (VAERS) is the US passive surveillance system monitoring vaccine safety. A major limitation of VAERS is the lack of denominator data (number of doses of administered vaccine), an element necessary for calculating reporting rates. Empirical Bayesian data mining, a data analysi...

journal_title：Vaccine

authors： Niu MT,Erwin DE,Braun MM

更新日期：2001-09-14 00:00:00

abstract：:Fusions of dendritic cells (DCs) and tumour cells have been shown to induce protective immunity to tumour challenge in animal models, and to represent a promising approach to cancer immunotherapy. The broader clinical application of this approach, however, is potentially constrained by the lack of replicative capacity...

journal_title：Vaccine

authors： Mohamed YS,Dunnion D,Teobald I,Walewska R,Browning MJ

更新日期：2012-10-12 00:00:00

abstract：:In order to evaluate the long-term immunity 2 and 3 years after booster vaccination against tick-borne encephalitis (TBE) following time intervals 3 years and longer since last TBE immunization, 195 (mean age 50.5+/-15.1 years) and 240 subjects (mean age 47.0+/-15.4 years), respectively, who had received a single boos...

journal_title：Vaccine

authors： Rendi-Wagner P,Paulke-Korinek M,Kundi M,Wiedermann U,Laaber B,Kollaritsch H

更新日期：2007-06-28 00:00:00

abstract：:For infants immunized with Haemophilus influenzae type b conjugate vaccines, booster immunization is usually recommended in the second year of life, typically between 12 and 18 months. This study assessed the effect of age at booster immunization on pre-immunization antibody trough levels and on subsequent responses, ...

journal_title：Vaccine

authors： Scheifele DW,Guasparini R,Lavigne P

更新日期：1999-02-12 00:00:00

abstract：:Recently the urgency of developing a pandemic influenza vaccine has lead to the re-evaluation of the use of whole virus vaccine. We have compared the humoral immune response and the protective efficacy of whole and split influenza virus vaccines in mice. Whole virus vaccine was more immunogenic particularly after the ...

journal_title：Vaccine

authors： Cox RJ,Hovden AO,Brokstad KA,Szyszko E,Madhun AS,Haaheim LR

更新日期：2006-11-10 00:00:00

abstract：BACKGROUND:Vaccination against Haemophilus influenzae type b (Hib) is included in routine pediatric immunization schedule in the United States. Previous vaccine shortages have created the need for additional options for Hib vaccination. METHODS:This phase III, randomized, multi-centered study (NCT01000974) evaluated t...

journal_title：Vaccine

authors： Klein NP,Abu-Elyazeed R,Cornish M,Leonardi ML,Weiner LB,Silas PE,Grogg SE,Varman M,Frenck RW,Cheuvart B,Baine Y,Miller JM,Leyssen M,Mesaros N,Roy-Ghanta S

更新日期：2017-06-16 00:00:00

abstract：:Norovirus (NoV) and hepatitis E virus (HEV) are both enterically-transmitted viruses causing gastroenteritis and hepatitis, respectively, in humans. While a vaccine against HEVs recently became available in China, there is no prophylactic or therapeutic approach against NoVs. Both NoV and HEV have surface protrusions ...

journal_title：Vaccine

authors： Wang L,Cao D,Wei C,Meng XJ,Jiang X,Tan M

更新日期：2014-01-16 00:00:00

abstract：:Schmallenberg virus (SBV), which emerged in 2011 in Central Europe and subsequently spread very rapidly throughout the continent, affects predominantly ruminants. SBV is transmitted by insect vectors, and therefore vaccination is one of the major tools of disease control. Only recently, a domain connected to virus neu...

journal_title：Vaccine

authors： Wernike K,Mundt A,Link EK,Aebischer A,Schlotthauer F,Sutter G,Fux R,Beer M

更新日期：2018-08-16 00:00:00

abstract：:The objectives of this study were to evaluate the effects of a therapeutic vaccine intervention with a modified-live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine on the dynamics of a heterologous viral infection in a population of pigs, and to determine the clinical and virological response of p...

journal_title：Vaccine

authors： Cano JP,Dee SA,Murtaugh MP,Pijoan C

更新日期：2007-05-30 00:00:00

abstract：BACKGROUND:Measles-containing vaccine (MCV) was introduced in 1965 in Beijing and given to the children aged 8m-14y. In population-based surveillance system, real-time polymerase chain reaction (RT-PCR) and immunoglobulin M(IgM) serology tests have been conducted for each suspected case since 2013. We used the surveill...

journal_title：Vaccine

authors： Ma R,Lu L,Suo L,Zhangzhu J,Chen M,Pang X

更新日期：2019-06-27 00:00:00

abstract：:The necessity of avoiding the use of animals in vaccine potency testing has been widely recognized. The repeatability and reproducibility of the Expected Percentage of Protection (EPP) as a serological potency surrogate for A24 Cruzeiro foot-and-mouth disease virus (FMDV) strain was assessed, and compared with the res...

journal_title：Vaccine

authors： Robiolo B,La Torre J,Maradei E,Beascoechea CP,Perez A,Seki C,Smitsaart E,Fondevila N,Palma E,Goris N,De Clercq K,Mattion N

更新日期：2010-08-31 00:00:00

abstract：:ArtinM and Jacalin (JAC) are lectins from the jackfruit (Artocarpus integrifolia) that have important role in modulation of immune responses to pathogens. Neospora caninum is an Apicomplexa parasite that causes neuromuscular disease in dogs and reproductive disorders in cattle, with economic impact on the livestock in...

journal_title：Vaccine

authors： Cardoso MR,Mota CM,Ribeiro DP,Santiago FM,Carvalho JV,Araujo EC,Silva NM,Mineo TW,Roque-Barreira MC,Mineo JR,Silva DA

更新日期：2011-11-15 00:00:00

abstract：:Plasmodium vivax is responsible for an approximate 35 million yearly human cases of malaria. Unfortunately, due to the low mortality rate associated with it and the difficulties of continuously in vitro culturing of this parasite, vaccine development against this human malaria has been largely neglected. In here, the ...

journal_title：Vaccine

authors： de Oliveira CI,Wunderlich G,Levitus G,Soares IS,Rodrigues MM,Tsuji M,del Portillo HA

更新日期：1999-08-06 00:00:00

abstract：:Cholera is a potentially lethal diarrhea disease caused by the gram-negative bacterium Vibrio cholerae. The need for an effective cholera vaccine is clearly indicated but the challenges of eliciting both systemic and mucosal immune responses remains a significant challenge. In the current report, we discovered that a ...

journal_title：Vaccine

authors： Xu G,Wang S,Zhuang L,Hackett A,Gu L,Zhang L,Zhang C,Wang H,Huang Z,Lu S

更新日期：2009-06-12 00:00:00

abstract：:Measles has been reemerging in South Korea since December 2018 resulting in 185 cases by September 2019. We calculated contact-adjusted immunity levels against measles in South Korea using national seroprevalence data in 2014, vaccination uptake rates, and an age-specific contact matrix. We further explored options to...

journal_title：Vaccine

authors： Chun JY,Park WB,Kim NJ,Choi EH,Funk S,Oh MD

更新日期：2020-01-10 00:00:00

abstract：:Neuromuscular diseases (NMDs) encompass a broad spectrum of conditions. Because infections may be relevant to the final prognosis of most NMDs, vaccination appears to be the simplest and most effective solution for protecting NMD patients from vaccine-preventable infections. However, very few studies have evaluated th...

journal_title：Vaccine

authors： Esposito S,Bruno C,Berardinelli A,Filosto M,Mongini T,Morandi L,Musumeci O,Pegoraro E,Siciliano G,Tonin P,Marrosu G,Minetti C,Servida M,Fiorillo C,Conforti G,Scapolan S,Ansaldi F,Vianello A,Castaldi S,Principi N,T

更新日期：2014-10-14 00:00:00

abstract：:To study the kinetics of humoral as well as cellular immunity to measles and to test for associated immunosuppression 124 12 month old children were studied twice, before routine MMR and either 14, 22, 30, or 38 days after vaccination. Plaque reduction neutralization (PRN) titres were determined at these time points a...

journal_title：Vaccine

authors： Pabst HF,Spady DW,Carson MM,Stelfox HT,Beeler JA,Krezolek MP

更新日期：1997-01-01 00:00:00

abstract：:Since vaccination against human papillomavirus (HPV) became available, awareness of HPV has dramatically increased. Implementation of a vaccine program varies internationally yet no studies have explored the influence this has on the public's knowledge of HPV. The present study aimed to explore differences in awarenes...

journal_title：Vaccine

authors： Marlow LA,Zimet GD,McCaffery KJ,Ostini R,Waller J

更新日期：2013-01-21 00:00:00

abstract：BACKGROUND:The challenge of keeping vaccines cold at health posts given the unreliability of power sources in many low- and middle-income countries and the expense and maintenance requirements of solar refrigerators has motivated the development of passive cold storage devices (PCDs), containers that keep vaccines cold...

journal_title：Vaccine

authors： Norman BA,Nourollahi S,Chen SI,Brown ST,Claypool EG,Connor DL,Schmitz MM,Rajgopal J,Wateska AR,Lee BY

更新日期：2013-10-25 00:00:00

abstract：:Aluminium-containing adjuvants are often used to enhance the potency of vaccines. In the present work we studied whether adsorption of diphtheria toxoid to colloidal aluminium hydroxide induces conformational changes of the antigen. Diphtheria toxoid has a high affinity for the aluminium hydroxide particles based on a...

journal_title：Vaccine

authors： Régnier M,Metz B,Tilstra W,Hendriksen C,Jiskoot W,Norde W,Kersten G

更新日期：2012-11-06 00:00:00

abstract：:In some serotypes of adenovirus (Ad), the penton base and attached trimeric fiber assemble into dodecameric virus-like particles called penton-dodecahedron (Pt-Dd), which can be internalized and used to deliver the vaccine antigens and drugs. Fowl adenovirus serotype 4 (FAdV-4) is an important pathogen, causing seriou...

journal_title：Vaccine

authors： Wang X,Tang Q,Qiu L,Yang Z

更新日期：2019-02-04 00:00:00

abstract：:How should public health authorities confront the threat of pandemic influenza? Is massive stockpiling the answer? If so, the costs could be overwhelming. Or is vaccination of pre-selected segments of the population the best approach? If so, then what about the tough ethical question that must be addressed: for whom--...

journal_title：Vaccine

authors：

更新日期：2006-11-10 00:00:00