Primary carcinoma of the gallbladder. The role of adjunctive therapy in its treatment.

Abstract:

:Of forty-three patients with carcinoma of the gallbladder discovered ih a twenty-five year period (during which 10,349 patients were diagnosed as having cholelithiasis), eighteen patients (42 per cent) had no obvious tumor outside of the gallbladder at the time of operation, nineteen patients (44 per cent) had local spread of the disease, and six patients (14 per cent) had abdominal carcinomatosis or distant metastasis. In the twenty-one patients who underwent surgical therapy for cure of their disease, the five year survival rate was 33 per cent. The more extensive surgical procedures (other than cholecystectomy alone) did not significantly increase survival. Neither the duration of the symptoms nor the pathologic type of the tumor altered the eventual outcome. No patients with tumor outside the gallbladder at the time of operation survived longer than two years. Compared to those who did not receive it, the fifteen patients treated postoperatively with adjunctive therapy (radiation therapy or chemotherapy or both) lived longer and also were significantly better palliated when tumor outside of the gallbladder was found at the time of operation. From these findings, the routine use of adjunctive therapy is recommended in all patients with disease outside of the gallbladder and serious consideration should be given to its use in all patients found to have carcinoma of the gallbladder.

journal_name

Am J Surg

authors

Treadwell TA,Hardin WJ

doi

10.1016/0002-9610(76)90439-6

subject

Has Abstract

pub_date

1976-12-01 00:00:00

pages

703-6

issue

6

eissn

0002-9610

issn

1879-1883

pii

0002-9610(76)90439-6

journal_volume

132

pub_type

杂志文章
  • Minimally invasive management of paraesophageal herniation in the high-risk surgical patient.

    abstract:BACKGROUND:Traditional management of symptomatic paraesophageal herniation involves hernia reduction, hiatal closure, and an antireflux procedure or gastropexy. Patients with significant comorbidities may not tolerate operative repair. A new technique, laparoscopic-assisted endoscopic reduction and fixation of the stom...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(01)00760-7

    authors: Kercher KW,Matthews BD,Ponsky JL,Goldstein SL,Yavorski RT,Sing RF,Heniford BT

    更新日期:2001-11-01 00:00:00

  • Intraoperative management of renal gunshot injuries: is mandatory exploration of Gerota's fascia necessary?

    abstract:BACKGROUND:Many trauma surgeons and trauma centers use routine exploration of Gerota's fascia (GE) for renal gunshot wounds (RGSW). The purpose of this study was to assess whether RGSW can be selectively explored for patients who undergo exploratory laparotomy. METHODS:Retrospective 10-year review of all patients who ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2015.09.023

    authors: Rostas J,Simmons JD,Frotan MA,Brevard SB,Gonzalez RP

    更新日期:2016-04-01 00:00:00

  • The demise of primary profundaplasty.

    abstract::Although the importance of the profunda femoris artery in maintenance of lower extremity integrity was recognized in the earliest days of modern vascular surgery, disappointment with the performance of primary profundaplasty has emerged fully only in recent years. During the 10 year period from 1977 to 1987, only 17 p...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(88)80371-4

    authors: Harward TR,Bergan JJ,Yao JS,Flinn WR,McCarthy WJ

    更新日期:1988-08-01 00:00:00

  • A modified frailty index predicts adverse outcomes among patients with colon cancer undergoing surgical intervention.

    abstract:INTRODUCTION:Assessing outcomes in patients with colon cancer (CC) undergoing surgical intervention is challenging. Frailty has been as established tool for assessing patient outcomes. The aim was of this study was to assess role of frailty in patients with CC. METHODS:National estimates for patients with CC were abst...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2018.07.006

    authors: Pandit V,Khan M,Martinez C,Jehan F,Zeeshan M,Koblinski J,Hamidi M,Omesieta P,Osuchukwu O,Nfonsam V

    更新日期:2018-12-01 00:00:00

  • A controlled clinical trial of whole gut lavage as a method of bowel preparation for colonic operations.

    abstract::In a prospective randomized clinical trial, whole gut lavage was evaluated against conventional mechanical cleansing for colonic operations. The lavage took less time to perform, was better tolerated by patients, and resulted in more satisfactory preparation as judged by frequency of collapsed intestines. There was no...

    journal_title:American journal of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-9610(79)90014-x

    authors: Chung RS,Gurll NJ,Berglund EM

    更新日期:1979-01-01 00:00:00

  • The impact of perioperative warm-up jackets on surgical site infection: cost without benefit?

    abstract:BACKGROUND:On July 1st, 2012, the University of Minnesota Medical Centers adopted a policy requiring all personnel to wear cover jackets in perioperative areas. This policy is based on the Association of Perioperative Registered Nurses recommended practice for cover jacket usage. We hypothesized that the cover jacket p...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2016.02.015

    authors: Chow CJ,Hayes LM,Saltzman DA

    更新日期:2016-11-01 00:00:00

  • Implications of peritoneal cytology for staging of early pancreatic cancer.

    abstract::Cytologic examination of peritoneal washings was performed in 40 patients with pancreatic ductal adenocarcinoma (35 head, 5 body) whose tumors had been selected as potentially resectable by computed tomographic (CT) findings. Saline (100 mL) was instilled and aspirated at laparoscopy in 27 patients and at laparotomy i...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(91)90356-i

    authors: Warshaw AL

    更新日期:1991-01-01 00:00:00

  • Breast conservation surgery for breast cancer at a regional medical center.

    abstract:BACKGROUND:This study examined trends in breast conservation surgery (BCS) at our hospital and factors associated with BCS. METHODS:We retrospectively reviewed breast cancer surgeries in patients eligible for BCS (size <4 cm, N0, N1) from 1990 through 1996 (n = 634). We calculated the yearly prevalence of BCS and used...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:

    authors: Kotwall C,Covington D,Churchill P,Brinker C,Weintritt D,Maxwell JG

    更新日期:1998-12-01 00:00:00

  • Using a video conference to teach clinical clerks in a one-week cardiothoracic clerkship.

    abstract:BACKGROUND:Students report that their operating room experience during specialty clerkships has been less than satisfactory. To deal with this and other problems in a 1-week cardiothoracic clerkship, a video conference system was introduced. METHODS:Three teaching strategies were used: a seminar dealing with the disea...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(96)00387-x

    authors: Amiel GE,Cohen R,Amar R,Sarafov I,Safadi T,Saute M,Porat E,Sharony R,Bolotin G,Tann M,Uretzky G

    更新日期:1997-04-01 00:00:00

  • Use of radionuclide lymphograms to determine lymphatic drainage of truncal melanomas.

    abstract::Radionuclide lymphograms provide invaluable preoperative information on many truncal melanomas of the skin that require elective regional lymph node dissection. ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(85)80138-0

    authors: Jones RF,Moe RE,Nelp W

    更新日期:1985-05-01 00:00:00

  • Enlarged parathyroid glands discovered in normocalcemic patients during thyroid surgery.

    abstract:BACKGROUND:This is a retrospective study analyzing data of normocalcemic patients with enlarged parathyroid glands discovered during thyroid surgery and comparing it with data of patients operated on for proved primary hyperparathyroidism. METHODS:The records of patients with enlarged parathyroid glands (group 1) and ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2007.01.033

    authors: Abboud B,Sleilaty G,Braidy C,Ghorra C,Abadjian G,Tohme C,Noun R,Sarkis R

    更新日期:2008-01-01 00:00:00

  • Molecular mechanisms of tumor formation.

    abstract::DNA is the fundamental guide for the cell's processes. The alterations in DNA that can lead to abnormal or absent proteins and the role of chromosomal alterations in changing the function of the DNA are reviewed. The role of viruses in derailing a cell's normal functions, the major mechanisms of oncogene action, and t...

    journal_title:American journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-9610(05)80911-0

    authors: Samara G,Hurwitz M,Sawicki M,Passaro E Jr

    更新日期:1992-10-01 00:00:00

  • The letters of William Stewart Halsted and John Chalmers DaCosta.

    abstract::William Stewart Halsted and John Chalmers DaCosta are two of the most distinguished surgeons in the history of medicine in the United States. Although their personalities were completely opposite, they enjoyed a long and devoted friendship. During their relationship, a fairly continuous correspondence was maintained. ...

    journal_title:American journal of surgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1016/0002-9610(89)90622-3

    authors: Rutkow IM

    更新日期:1987-09-01 00:00:00

  • Postoperative quality of life after laparoscopy-assisted pylorus-preserving gastrectomy compared With laparoscopy-assisted distal gastrectomy: A cross-sectional postal questionnaire survey.

    abstract:BACKGROUND:Little is known about postgastrectomy syndrome and quality of life (QOL after laparoscopy-assisted pylorus-preserving gastrectomy (LAPPG). The aim of this study was to assess postgastrectomy syndrome and QOL after LAPPG as compared with laparoscopy-assisted distal gastrectomy with Billroth-I reconstruction (...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2016.09.041

    authors: Hosoda K,Yamashita K,Sakuramoto S,Katada N,Moriya H,Mieno H,Watanabe M

    更新日期:2017-04-01 00:00:00

  • Role of intraoperative pancreatography in patients with injury to the pancreas.

    abstract::Over a 10 year period, 54 patients presented with pancreatic trauma. During the first 5 years of the study, when pancreatography was not utilized for the assessment of pancreatic duct injury, 55 percent of the patients had major pancreatic complications. During the subsequent 5 years, suspected proximal duct injury wa...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(82)90173-8

    authors: Berni GA,Bandyk DF,Oreskovich MR,Carrico CJ

    更新日期:1982-05-01 00:00:00

  • Acute histologic inflammatory activity and postoperative outcomes in pediatric patients with ulcerative colitis.

    abstract:BACKGROUND:The aim of this study was to determine whether acute histologic inflammatory activity at the rectal margin predicts postoperative complications in children with ulcerative colitis following ileal pouch-anal anastomoses (IPAA). METHODS:Patients who underwent IPAA following previous total abdominal colectomy ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2020.02.054

    authors: Onwuka E,Huntington J,Onwuka A,Prasad V,Nwomeh B

    更新日期:2020-04-01 00:00:00

  • Surgical considerations in hyperparathyroidism: reappraisal of the need for multigland biopsy.

    abstract::Sixty-seven cases of neck exploration for suspected hyperparathyroidism were reviewed. Thirty-nine patients underwent removal of an adenoma with biopsy of one or more other parathyroid glands. In another group, nine patients underwent removal of the adenoma only. Both groups have had no recurrences of hyperparathyroid...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(76)90389-5

    authors: Seyfer AE,Sigdestad JB,Hirata RM

    更新日期:1976-09-01 00:00:00

  • In situ saphenous vein bypass grafting. Experience in 34 extremities over a 2 year period.

    abstract::Over a 2 year period, 34 limbs were revascularized in 33 patients. The in situ saphenous vein technique was used. Improved instrumentation and patency rates have encouraged the use of this method. Eighteen patients were insulin-dependent diabetics. The indication for operation was limb salvage in 25 limbs (73 percent)...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(83)90108-3

    authors: Hallin RW

    更新日期:1983-05-01 00:00:00

  • Weight loss and early and late complications--the international experience.

    abstract::Following its introduction in 1993, the LAP-BAND (INAMED Health, Santa Barbara, CA) has been used extensively across the world for the treatment of obesity, and data on safety and effectiveness are now available. This review draws on the literature and our own clinical patient base to provide an overview of the early ...

    journal_title:American journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-9610(02)01179-0

    authors: O'Brien PE,Dixon JB

    更新日期:2002-12-01 00:00:00

  • An Internet-based survey of factors influencing medical student selection of a general surgery career.

    abstract:BACKGROUND:This study descriptively analyzes characteristics of general surgery residency and practice and their influence on student interest in surgical careers. METHODS:Fourth-year medical students were invited to complete an Internet-based survey. A 5-point Likert scale described characteristics of general surgery...

    journal_title:American journal of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.amjsurg.2005.03.019

    authors: Cochran A,Melby S,Neumayer LA

    更新日期:2005-06-01 00:00:00

  • A single institution's experience with transperitoneal laparoscopic hernia repair.

    abstract:BACKGROUND:Previous evaluations of endoscopic hernia surgery mostly are based on small prospectively documented series or on a few randomized comparative studies. In the following, results of a large single-institution experience concerning the transabdominal preperitoneal patch (TAPP) technique with regard to the deve...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(98)00074-9

    authors: Leibl BJ,Schmedt CG,Schwarz J,Däubler P,Kraft K,Schlossnickel B,Bittner R

    更新日期:1998-06-01 00:00:00

  • Preoperative selection of patients for lumbar sympathectomy by use of the Doppler index.

    abstract::Yao and Bergan [8] have shown that an ankle systolic index of more than 0.25 is associated with a high rate of success from lumbar sympathectomy. This association has been borne out in our small series. We have also suggested that diseases that obviously compromise collateral circulation might be a relative contraindi...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(77)90316-6

    authors: Seeger JM,Lazarus HM,Albo D Jr

    更新日期:1977-12-01 00:00:00

  • Asymptomatic carotid stenosis. Immediate and long-term results after prophylactic endarterectomy.

    abstract::1. A review of the immediate and long-term results of prophylactic carotid endarterectomy for asymptomatic lesions of 78 carotid arteries in 72 patients between 1961 and 1976 is presented. 2. The inhospital operative mortality was zero. Two patients experienced postoperative transient neurologic deficit with complete ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(79)90375-1

    authors: Moore WS,Boren C,Malone JM,Goldstone J

    更新日期:1979-08-01 00:00:00

  • Natural history of the leg amputee.

    abstract::For 173 patients undergoing major leg amputations, the operative mortality was 13 per cent. The ratio of below-knee (BK) to above-knee (AK) amputations was approximately unity. Of the 150 patients who survived amputation, 93 were given prostheses. Amoung the latter group, 76 per cent of the unilateral AK amputees and ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(77)90133-7

    authors: Couch NP,David JK,Tilney NL,Crane C

    更新日期:1977-04-01 00:00:00

  • Clinicopathological analysis of local spread of carcinoma of the tongue.

    abstract:BACKGROUND:The aims of the study are three-dimensional analysis of mode and distance of local spread of oral tongue carcinoma. METHODS:The glossectomy specimens were examined in the coronal plane in 3 mm thickness section. RESULTS:There were 50 glossectomy specimens. The maximum spread was 1.8 cm. Ninety-six percent ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(97)00282-1

    authors: Yuen PW,Lam KY,Chan AC,Wei WI,Lam LK

    更新日期:1998-03-01 00:00:00

  • Complete coverage of in situ aortograft by total omental pedicle flap as the most reliable treatment of aortoesophageal fistula.

    abstract::Aortoesophageal fistula secondary to a thoracic aortic aneurysm is usually a fatal disease with few survivors reported previously. We encountered 2 consecutive patients who were treated successfully with esophagectomy and in situ aorta reconstruction using cryopreserved homograft that was wrapped completely with oment...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2005.09.011

    authors: Kitayama J,Morota T,Kaisaki S,Nakayama H,Ishigami H,Yamashita H,Ishikawa M,Shibata K,Takamoto S,Nagawa H

    更新日期:2006-07-01 00:00:00

  • Preoperative parathyroid localization does not improve surgical outcomes for patients with primary hyperparathyroidism.

    abstract:BACKGROUND:Most patients with primary hyperparathyroidism undergo localization prior to operation with variable success. Therefore, in this study we investigated the safety of parathyroidectomy without imaging. METHODS:A prospective database of 2057 surgical patients with primary hyperparathyroidism from 2001 to 2019 ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2020.04.029

    authors: Fazendin JM,Lindeman B,Chen H

    更新日期:2020-09-01 00:00:00

  • Parotid gland tumors. Clinicopathologic study.

    abstract::The clinical findings and histologic features of 154 parotid gland tumors treated at the Health Sciences Centre, Winnipeg, Canada, from 1957 to 1970 were reviewed. The study illustrates a wide variation in the natural history and degree of malignancy of parotid tumors. Approximately 80 per cent were benign; among thes...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(75)90344-x

    authors: Sinha BK,Buntine DW

    更新日期:1975-06-01 00:00:00

  • A systematic review of the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity and its Portsmouth modification as predictors of post-operative morbidity and mortality in patients undergoing pancreatic surgery.

    abstract:BACKGROUND:The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) model and its Portsmouth modification (P-POSSUM) are used extensively to predict postoperative mortality and morbidity in general surgery. The aim of this study was to undertake the first systematic review ...

    journal_title:American journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.amjsurg.2012.06.011

    authors: Wang H,Chen T,Wang H,Song Y,Li X,Wang J

    更新日期:2013-04-01 00:00:00

  • Advantages of laparoscopic transabdominal preperitoneal herniorrhaphy in the evaluation and management of inguinal hernias.

    abstract:BACKGROUND:Laparoscopic transabdominal preperitoneal (TAPP) herniorrhaphy provides an opportunity to definitively evaluate both inguinal areas without the need for additional dissection. We aimed to establish the rates and contributing patient factors to errors in the preoperative assessment. METHODS:A retrospective r...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2006.10.015

    authors: Novitsky YW,Czerniach DR,Kercher KW,Kaban GK,Gallagher KA,Kelly JJ,Heniford BT,Litwin DE

    更新日期:2007-04-01 00:00:00