当前位置： SCI文献检索 > JOURNAL OF AFFECTIVE DISORDERS期刊下所有文献 > [3H] imipramine binding in brain samples from depressed suicides and controls: 5-HT uptake sites compared with sites defined by desmethylimipramine.

[3H] imipramine binding in brain samples from depressed suicides and controls: 5-HT uptake sites compared with sites defined by desmethylimipramine.

Abstract：

:Using desmethylimipramine (DMI) defined and Na+ dependent [3H]imipramine binding, we have examined both 5-HT uptake sites and sites unrelated to 5-HT uptake, in frontal cortex, putamen and substantia nigra of suicides with a firm retrospective diagnosis of depression and matched controls. No differences were seen between antidepressant-free suicides and controls, although [3H]imipramine binding sites were significantly lower in putamen of the subgroup of non-violent suicides. The number of DMI defined [3H]imipramine binding sites was also significantly lower in putamen of antidepressant-treated suicides.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Lawrence KM,Kanagasundaram M,Lowther S,Katona CL,Crompton MR,Horton RW

doi

10.1016/s0165-0327(97)00126-2

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

105-12

issue

1-3

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(97)00126-2

journal_volume

47

pub_type

杂志文章

相关文献

JOURNAL OF AFFECTIVE DISORDERS文献大全
  • Human fibroblasts as a relevant model to study signal transduction in affective disorders.

    abstract：BACKGROUND:Previous studies have demonstrated a blunted beta adrenoceptor-linked protein kinase A (PKA) response in the 900xg supernatant fraction of human fibroblasts cultured from patients with major depression. RESULTS:Results of the present studies demonstrate a significant reduction in the B(max) value of [3H]cyc...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(99)00190-1

    authors： Manier DH,Shelton RC,Ellis TC,Peterson CS,Eiring A,Sulser F

    更新日期：2000-12-01 00:00:00

  • Bipolar I affective disorder: predictors of outcome after 15 years.

    abstract：BACKGROUND:Robust predictors of long-term outcome in bipolar affective disorder would have substantial importance to both clinicians and researchers. Such predictors are not available, however, perhaps because of the limitations of previous efforts to find them. METHODS:In this study, 113 patients with bipolar affecti...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(98)00043-3

    authors： Coryell W,Turvey C,Endicott J,Leon AC,Mueller T,Solomon D,Keller M

    更新日期：1998-09-01 00:00:00

  • The sick role, illness cognitions and outcomes in bipolar disorder.

    abstract：OBJECTIVE:In some individuals, recovery from episodes of mental illness may be impeded by maladaptive illness beliefs and behaviors. For individuals with chronic illness, acceptance of its presence and consequences is necessary to seek appropriate treatment, adjust their lifestyle, and adhere to recommended management ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2012.07.003

    authors： Berk M,Berk L,Dodd S,Fitzgerald PB,de Castella AR,Filia S,Filia K,Brnabic AJ,Kelin K,Montgomery W,Kulkarni J,Stafford L

    更新日期：2013-03-20 00:00:00

  • Default mode network subsystem alterations in bipolar disorder during major depressive episode.

    abstract：BACKGROUND:Default mode network (DMN) has been widely reported to be altered in bipolar disorder during major depressive episode (BDD). Recent studies supported the idea that DMN is not an unitary system, but composed of smaller and distinct functional subsystems. The current study aimed to investigate the abnormal fun...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.11.049

    authors： Yang Y,Cui Q,Lu F,Pang Y,Chen Y,Tang Q,Li D,Lei T,He Z,Hu S,Deng J,Chen H

    更新日期：2021-02-15 00:00:00

  • Neuroendocrine studies in affective disorders. Part 1. Plasma prolactin response to thyrotropin-releasing hormone in affective disorders: effect of ECT.

    abstract：:The plasma prolactin response to thyrotropin-releasing hormone, which is thought to be mediated by central 5-HT mechanisms, has been studied in patients with affective disorders. There was no difference between depressive patients (taken as a whole), bipolar patients undergoing a manic phase and controls in the prolac...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(80)90032-4

    authors： Coppen A,Rao VA,Bishop M,Abou-Saleh MT,Wood K

    更新日期：1980-12-01 00:00:00

  • The associations of interpersonal sensitivity with mental distress and trait aggression in early adulthood: a prospective cohort study.

    abstract：BACKGROUND:To explore the longitudinal associations of interpersonal sensitivity (IS) with mental distress and trait aggression among participants passing through adolescence into adulthood. METHODS:A total of 306 participants were recruited at baseline and received a 24-month follow-up. Questionnaires investigating s...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.03.161

    authors： Sun J,Zhang X,Wang Y,Wang J,Li J,Cao F

    更新日期：2020-07-01 00:00:00

  • A longitudinal study of BDNF promoter methylation and genotype with poststroke depression.

    abstract：INTRODUCTION:Brain derived neurotrophic factor (BDNF) has been shown to play an important role in the pathophysiology of mood disorders including poststroke depression (PSD). BDNF secretion is influenced by epigenetic and genetic profiles. This study aimed to investigate whether BDNF gene promoter methylation status an...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.01.008

    authors： Kim JM,Stewart R,Kang HJ,Kim SY,Kim SW,Shin IS,Park MS,Kim HR,Shin MG,Cho KH,Yoon JS

    更新日期：2013-07-01 00:00:00

  • Prefrontal and amygdala engagement during emotional reactivity and regulation in generalized anxiety disorder.

    abstract：BACKGROUND:Emotion dysregulation is prominent in generalized anxiety disorder (GAD), characterized clinically by exaggerated reactivity to negative stimuli and difficulty in down-regulating this response. Although limited research implicates frontolimbic disturbances in GAD, whether neural aberrations occur during emot...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.05.013

    authors： Fitzgerald JM,Phan KL,Kennedy AE,Shankman SA,Langenecker SA,Klumpp H

    更新日期：2017-08-15 00:00:00

  • BP neural network prediction model for suicide attempt among Chinese rural residents.

    abstract：OBJECTIVE:This study aimed to establish and assess the Back Propagation Neural Network (BPNN) prediction model for suicide attempt, so as to improve the individual prediction accuracy. METHOD:Data was collected from a wide range case-control suicide attempt survey. 659 serious suicide attempters (case group) were rand...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.12.111

    authors： Lyu J,Zhang J

    更新日期：2019-03-01 00:00:00

  • Detecting risk of suicide attempts among Chinese medical college students using a machine learning algorithm.

    abstract：BACKGROUND:Suicide has become one of the most prominent concerns for public health and wellness; however, detecting suicide risk factors among individuals remains a big challenge. The aim of this study was to develop a machine learning algorithm that could effectively and accurately identify the probability of suicide ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.04.057

    authors： Shen Y,Zhang W,Chan BSM,Zhang Y,Meng F,Kennon EA,Wu HE,Luo X,Zhang X

    更新日期：2020-08-01 00:00:00

  • Complex trauma and intimate relationships: the impact of shame, guilt and dissociation.

    abstract：BACKGROUND:This study examined dissociation, shame, guilt and intimate relationship difficulties in those with chronic and complex PTSD. Little is known about how these symptom clusters interplay within the complex PTSD constellation. Dissociation was examined as a principle organizing construct within complex PTSD. In...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2012.10.010

    authors： Dorahy MJ,Corry M,Shannon M,Webb K,McDermott B,Ryan M,Dyer KF

    更新日期：2013-05-01 00:00:00

  • Shame, pride, and suicidal ideation in a military clinical sample.

    abstract：BACKGROUND:Suicide risk among U.S. military personnel has been increasing over the past decade. Fluid vulnerability theory (FVT; Rudd, 2006) posits that acute suicidal episodes increase in severity when trait-based (e.g., shame) and state-based (e.g., hopelessness) risk factors interact, especially among individuals wh...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2012.11.006

    authors： Bryan CJ,Ray-Sannerud B,Morrow CE,Etienne N

    更新日期：2013-05-01 00:00:00

  • Interval between symptom onset and hospitalization in mania.

    abstract：:Previous studies of illness onset in mania lack a frequency distribution for the interval between symptom onset and hospitalization (hospital latency), although a bimodal distribution of illness onset been suggested. We identified 100 patients hospitalized for mania and found a unimodal distribution, with mean +/- SD ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(94)90027-2

    authors： Francis A,Gasparo P

    更新日期：1994-07-01 00:00:00

  • Valproate for the treatment of acute bipolar depression: systematic review and meta-analysis.

    abstract：BACKGROUND:Our aim was to analyse existing data on the efficacy and tolerability of valproate for the treatment of acute bipolar depression. METHODS:Randomized controlled trials comparing valproate with placebo were identified using searches of electronic databases in October 2008. Outcomes investigated were depressio...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jad.2009.10.033

    authors： Smith LA,Cornelius VR,Azorin JM,Perugi G,Vieta E,Young AH,Bowden CL

    更新日期：2010-04-01 00:00:00

  • One year clinical and psychosocial outcomes of early-onset chronic depression.

    abstract：BACKGROUND:Results from short-term treatment studies have demonstrated the efficacy of antidepressant medications for outpatients with early-onset chronic depression. However, scant data exists regarding the long-term outcome of these patients treated for this disorder. METHODS:The author conducted a one-year naturali...

    journal_title：Journal of affective disorders

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0165-0327(98)00040-8

    authors： Agosti V

    更新日期：1999-07-01 00:00:00

  • Where the depressed mind wanders: Self-generated thought patterns as assessed through experience sampling as a state marker of depression.

    abstract：BACKGROUND:Self-generated thoughts (SGTs), such as during mind wandering, occupy much of our waking life. Individuals with Major Depressive Disorder (MDD) are less in the "here and now" and prone to rumination. Few studies have looked at SGTs in depression using experience sampling methods and no study has so far inves...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2016.03.005

    authors： Hoffmann F,Banzhaf C,Kanske P,Bermpohl F,Singer T

    更新日期：2016-07-01 00:00:00

  • Cannabis use, depression and anxiety: A 3-year prospective population-based study.

    abstract：BACKGROUND:Whether or not cannabis use may increase the risk for depression and/or anxiety is not clear. For one thing, it has not been possible to draw a definitive conclusion regarding the direction of causality, i.e. whether cannabis use increases the risk for depression/anxiety or vice versa. This study aimed at ex...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2015.12.045

    authors： Danielsson AK,Lundin A,Agardh E,Allebeck P,Forsell Y

    更新日期：2016-03-15 00:00:00

  • Affective reactivity to daily life stress: Relationship to positive psychotic and depressive symptoms in a general population sample.

    abstract：INTRODUCTION:Increased affective reactivity to daily life stress has been found in individuals with psychosis and depression, and in those at risk for these conditions. Because depressive and psychotic symptoms often co-occur, increased affective reactivity in these disorders may be explained by the presence of depress...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.08.051

    authors： Booij SH,Snippe E,Jeronimus BF,Wichers M,Wigman JTW

    更新日期：2018-01-01 00:00:00

  • The neural correlates of reward-related processing in major depressive disorder: a meta-analysis of functional magnetic resonance imaging studies.

    abstract：BACKGROUND:A growing number of functional magnetic resonance imaging (fMRI) studies have been conducted in major depressive disorder (MDD) to elucidate reward-related brain functions. The aim of this meta-analysis was to examine the common reward network in the MDD brain and to further distinguish the brain activation ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jad.2013.06.039

    authors： Zhang WN,Chang SH,Guo LY,Zhang KL,Wang J

    更新日期：2013-11-01 00:00:00

  • Maternal attachment style and psychiatric history as independent predictors of mood symptoms in the immediate postpartum period.

    abstract：BACKGROUND:There is evidence that both a past history of psychiatric illness and insecure attachment put women at risk for mood disturbances in the postpartum period. The aim of this study was to ascertain whether maternal insecure attachment is a risk factor for mood symptoms in the immediate postpartum period indepen...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.01.039

    authors： Croce Nanni R,Troisi A

    更新日期：2017-04-01 00:00:00

  • Concordance between clinician-rated and patient reported outcome measures of depressive symptoms in treatment resistant depression.

    abstract：BACKGROUND:Calls to implement measurement-based care (MBC) in psychiatry are increasing. A recent Cochrane meta-analysis concluded that there is insufficient evidence that routine application of patient reported outcomes (PROs) improves treatment outcomes for common psychiatric disorders. There is a particular paucity ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.01.108

    authors： Hershenberg R,McDonald WM,Crowell A,Riva-Posse P,Craighead WE,Mayberg HS,Dunlop BW

    更新日期：2020-04-01 00:00:00

  • Relevance of tryptophan and tyrosine availability in endogenous and 'non-endogenous' depressives treated with imipramine or clomipramine.

    abstract：:This study was performed on 65 depressed in-patients who were included in previously reported trials of imipramine and clomipramine. Before and during treatment, blood samples were collected for estimation of the availability of tryptophan and tyrosine by measurement of their plasma ratios to competing amino acids, an...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(81)90025-2

    authors： Møller SE,Reisby N,Ortmann J,Elley J,Krautwald O

    更新日期：1981-09-01 00:00:00

  • Disruptive behavior disorders in offspring of parents with major depression: associations with parental behavior disorders.

    abstract：OBJECTIVE:Although the offspring of parents with major depressive disorder (MDD) are at increased risk to develop disruptive behavior disorders (DBD) in addition to MDD, it remains unclear whether this heightened risk is due to MDD or to comorbid DBD in the parents. METHOD:In a secondary analysis of longitudinal data ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2008.02.019

    authors： Hirshfeld-Becker DR,Petty C,Micco JA,Henin A,Park J,Beilin A,Rosenbaum JF,Biederman J

    更新日期：2008-12-01 00:00:00

  • A revised interpretation of the TRH test results in female depressed patients. Part I: TSH responses. Effects of severity of illness, thyroid hormones, monoamines, age, sex hormonal, corticosteroid and nutritional state.

    abstract：:Thyrotropin secreting hormone (TSH) levels were recorded in baseline conditions and 20 and 60 min after thyrotropin releasing hormone (TRH) administration (200 micrograms i.v.) in 60 depressed females categorized according to DSM-III. Basal TSH (TSHB) and peak TSH responses (TSHP) were measured using ultrasensitive RI...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(89)90075-x

    authors： Maes M,Vandewoude M,Maes L,Schotte C,Cosyns P

    更新日期：1989-03-01 00:00:00

  • Trait impulsivity in patients with mood disorders.

    abstract：BACKGROUND:Impulsivity is a key component of the manic behavior of bipolar disorder and is reported to occur in bipolar patients as a stable characteristic, i.e. a trait. Nevertheless, impulsivity has not been widely studied in depressed bipolar patients. We assessed impulsivity in depressed and euthymic bipolar and un...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2006.09.037

    authors： Peluso MA,Hatch JP,Glahn DC,Monkul ES,Sanches M,Najt P,Bowden CL,Barratt ES,Soares JC

    更新日期：2007-06-01 00:00:00

  • Clinical efficacy of kava extract WS 1490 in sleep disturbances associated with anxiety disorders. Results of a multicenter, randomized, placebo-controlled, double-blind clinical trial.

    abstract：BACKGROUND:The aim of the present trial was to investigate the efficacy and safety of kava special extract WS 1490 in patients with sleep disturbances associated with anxiety, tension and restlessness states of non-psychotic origin. METHODS:In a multicenter, randomized, double-blind clinical study, 61 patients receive...

    journal_title：Journal of affective disorders

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0165-0327(02)00238-0

    authors： Lehrl S

    更新日期：2004-02-01 00:00:00

  • The role of prenatal social support in social inequalities with regard to maternal postpartum depression according to migrant status.

    abstract：BACKGROUND:An advantaged socioeconomic position (SEP) and satisfying social support during pregnancy (SSP) have been found to be protective factors of maternal postpartum depression (PDD). An advantaged SEP is also associated with satisfying SSP, making SSP a potential mediator of social inequalities in PPD. SEP, SSP a...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.04.024

    authors： Nakamura A,El-Khoury Lesueur F,Sutter-Dallay AL,Franck JÈ,Thierry X,Melchior M,van der Waerden J

    更新日期：2020-07-01 00:00:00

  • Determinants of occupational and residential functioning in bipolar disorder.

    abstract：BACKGROUND:Bipolar disorder is associated with reduced rates of employment and residential independence. The influence of cognitive impairment and affective symptoms on these functional attainments has received little previous attention and is the focus of this study. METHOD:A total of 229 adult outpatients with bipol...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2011.09.035

    authors： Depp CA,Mausbach BT,Bowie C,Wolyniec P,Thornquist MH,Luke JR,McGrath JA,Pulver AE,Harvey PD,Patterson TL

    更新日期：2012-02-01 00:00:00

  • A review of panic and suicide in bipolar disorder: does comorbidity increase risk?

    abstract：INTRODUCTION:Bipolar mood disorder carries a serious suicide risk. Panic disorder, which also confers an independent risk of suicide and psychiatric comorbidity, in general has been found to amplify suicidality in mood-disordered patients. This article assesses the available literature on how panic and suicide relate t...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2008.09.014

    authors： Kilbane EJ,Gokbayrak NS,Galynker I,Cohen L,Tross S

    更新日期：2009-05-01 00:00:00

  • Effects of antidepressant medication on emotion regulation in depressed patients: an iSPOT-D report.

    abstract：BACKGROUND:Antidepressant medication (ADM) is thought to reduce depressive symptoms by altering emotion-generative brain systems. However, it is unknown whether successful ADM treatment is associated with changes in psychobehavioral strategies used to regulate emotions. We examined depressive symptoms and emotion regul...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jad.2013.12.037

    authors： McRae K,Rekshan W,Williams LM,Cooper N,Gross JJ

    更新日期：2014-04-01 00:00:00