Abstract:
:Previous studies have suggested that hepatic arterial flow in heterotopic partial liver transplants is necessary to ensure graft survival and regenerative capacity. This report presents findings in a syngeneic rat strain (Lewis) that partial liver transplants can be successfully heterotopically transplanted in the long term with the only inflow coming from the portal vein. When the host liver undergoes a nearly complete resection at 3-4 weeks, the transplanted liver regenerates to maintain the health of the host. Moderate to massive hepatocellular necrosis occurs in the first 3 months postoperatively, with recovery by 4-5 months. Liver transplants 8-10 months postoperatively appear architecturally normal. No host liver tissues were found to be regenerating after subtotal host liver resection. We conclude that portal vein reconstruction without hepatic arterial inflow can sustain a partial liver transplant in the long term, replacing the function of the host liver.
journal_name
Microsurgeryjournal_title
Microsurgeryauthors
Yoo CH,Wang Y,Ha J,Mao L,Kim S,Tarin T,Wolf P,Youngkin TP,Brems JJ,Gittes RF,D'Silva M,Lee Sdoi
10.1002/(sici)1098-2752(1999)19:2<78::aid-micr7>3.subject
Has Abstractpub_date
1999-01-01 00:00:00pages
78-82issue
2eissn
0738-1085issn
1098-2752pii
10.1002/(SICI)1098-2752(1999)19:2<78::AID-MICR7>3.journal_volume
19pub_type
杂志文章相关文献
MICROSURGERY文献大全abstract::Five young adults between the ages of 16 and 27 years underwent mandibular reconstruction with free vascularized iliac crest bone grafts based on the deep circumflex iliac artery. These were the only patients under age 30 years in a series of over 60 patients undergoing this procedure. In all cases, the ipsilateral cr...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920090216
更新日期:1988-01-01 00:00:00
abstract::This study compares nerve repair following tissue expansion with nerve repair using an interposed graft in the rat. Group I had expansion conducted over 2 weeks at 40 mmHg. A 4 mm segment was excised from the lengthened nerve and repaired primarily. Group II had a 4 mm segment of nerve excised and then replaced as an ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920150614
更新日期:1994-01-01 00:00:00
abstract:AIM:The clinical value of adipofascial flaps based on distal ulnar or radial-artery perforators is demonstrated in a series of 14 patients with severe hand injuries and significant soft tissue defects requiring coverage. MATERIAL AND METHODS:There were 10 male and 4 female patients, aged between 23 and 72 years. The d...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20374
更新日期:2007-01-01 00:00:00
abstract::The bridging of nerve gaps is still one of the major problems in peripheral nerve surgery. The present experiment describes our attempt to engineer different biologic nerve grafts in a rat sciatic nerve model: cultured isogenic Schwann cells were implanted into 2-cm autologous acellular nerve grafts or autologous pred...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10056
更新日期:2002-01-01 00:00:00
abstract::Nerve regeneration using artificial biodegradable conduits is of increasing interest. The aim of this study is to evaluate the regeneration and maturation of a nerve after long-term implantation (2 years) of a biodegradable poly-L-lactide/poly-epsilon-caprolactone (PLLA/PCL) copolymeric nerve guide in the sciatic nerv...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920140808
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Previous neck dissection and irradiation is believed to affect the success of free tissue transfers in head and neck reconstruction, but evidence is scarce and conflicting. This study seeks to evaluate flap success rates in the presence of these two factors. METHODS:Over a ten-year period, a total of 853 fr...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22270
更新日期:2014-11-01 00:00:00
abstract::We examined the results after implantation of ovarian follicles by various modes in a total of 82 cases. One or five ovarian follicles were implanted into spleens in castrated female rats. In 20 cases among these, each five follicles were implanted into native and transplanted spleens after spleen transplantation (dou...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10186
更新日期:2003-01-01 00:00:00
abstract::A case is presented where both the ulnar nerve and palmaris profundus tendon were found within the carpal tunnel during routine open decompression for carpal tunnel syndrome. ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10196
更新日期:2004-01-01 00:00:00
abstract::Intrinsic haemangioma of the median nerve is an extremely rare tumor that represents a challenge to diagnose and treat. Only a few cases have been reported in the literature. We present a 10-year-old girl who was diagnosed having an intrinsic haemangioma of the median nerve and treated with total surgical resection of...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.20456
更新日期:2008-01-01 00:00:00
abstract::The iliac crest is reevaluated with respect to the rapid evolution of vascularized mandibular reconstruction. With more flaps to choose from, indications for the crest have become more specific-playing to the strengths of this particular transfer. Ideally, defects should exclude soft tissue and occupy lateral segments...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920150406
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:The probability of spontaneous recovery of shoulder external rotation in neonatal brachial plexus injury (NBPI) is very low after the age of 18 months. We report the outcomes of double nerve transfers to restore active external rotation of the glenohumeral joint in children with NBPI after this age. PATIE...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30616
更新日期:2020-11-01 00:00:00
abstract::A case of complex microsurgical reconstruction of the dorsum of the foot, including tendon transfer following tumor resection, in a 15-week-old male infant is presented. After birth, a 5.5 x 4 cm large tumor was observed on the dorsum of the right foot. Biopsy showed a congenital malignant fibro sarcoma. After initial...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20266
更新日期:2006-01-01 00:00:00
abstract::The results of a 3-year study in which a series of 355 implantations of 1-cm-long fibrous polyurethane microvascular prostheses into the infrarenal aorta of the rat (group A) were evaluated with respect to patency and formation, structure, and fate of the neo-intima. Rats were sacrificed at various intervals from 1 da...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920060306
更新日期:1985-01-01 00:00:00
abstract:INTRODUCTION:Calcaneal tumors being a rare occurrence, surgical options and outcomes are not well-known. Extensive defects following wide resection, especially in weight-bearing areas, still remain a challenge and different reconstructive techniques have been proposed. The aim of this report was to analyze the clinical...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30452
更新日期:2019-11-01 00:00:00
abstract::Tendocutaneous free flap transfer has been used to treat troublesome wounds involving skin and tendons, with the dorsum of the foot being the most frequent donor site. Free flaps consist of the dorsalis pedis artery, saphenous vein, branch of the superficial peroneal nerve, long extensor tendons, and overlying skin. W...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920151211
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Composite defects of bone and soft tissues represent a reconstructive challenge. Several techniques have been described in the medical literature; however, extensive composite defects should be reconstructed with microvascular free tissue transfer. The purpose of this report is to present the use of a compos...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22067
更新日期:2013-03-01 00:00:00
abstract::The distally-based anterolateral thigh flap is an attractive option for proximal leg and knee coverage but venous congestion is common. Restoration of antegrade venous drainage via great saphenous vein supercharge to the proximal flap vein is proposed. The purpose of this study was to evaluate and compare outcomes of ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22380
更新日期:2016-01-01 00:00:00
abstract::This study was designed to evaluate the effects of crush injuries to the feeding arteries of a muscle flap on microcirculatory haemodynamics. Eighteen male Sprague-Dawley rats were divided into three experimental groups for intravital microscopy of the cremaster muscle flap. Group 1 served as control. In group 2 the c...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(sici)1098-2752(1999)19:8<364::aid-micr3>3
更新日期:1999-01-01 00:00:00
abstract::This study demonstrates that intravenous epinephrine causes arterial vasospasm, but not venous constriction, in the microcirculation of the rat cremaster muscle. This effect can be blocked by a smooth muscle relaxant such as papaverine or an alpha receptor antagonist such as phentolamine. Circulating vasospastic agent...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920120111
更新日期:1991-01-01 00:00:00
abstract::In September 1998, a surgical team in Lyon, France, performed the first successful hand transplant. After this historic event, in January 1999, the University of Louisville performed the first hand transplant in the United States. These events sparked interest and debate concerning the justification of performing limb...
journal_title:Microsurgery
pub_type: 历史文章,杂志文章,评审
doi:10.1002/1098-2752(2000)20:8<393::aid-micr9>3.0.co;
更新日期:2000-01-01 00:00:00
abstract::Two patients with massive, composite defects of the total lower lip, chin, and anterior mandible underwent double free-flap reconstruction. A fibular osteoseptocutaneous flap was used to reconstruct the mandible and floor of the mouth and a radial forearm fasciocutaneous composite flap, including the palmaris longus t...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(sici)1098-2752(1998)18:6<372::aid-micr6>3
更新日期:1998-01-01 00:00:00
abstract::Big craniofacial resections for highly invasive malignant neoplasm, including skull base and maxillary bones, always represent a difficult chance for the reconstructive surgeon. In these cases it is not easy to restore anatomy and function simultaneously even adopting complex microsurgical techniques. In maxillofacial...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20694
更新日期:2010-01-01 00:00:00
abstract::Between 1987-2002, omental free-tissue transfer was used in 11 patients, aged 6-65 years (mean age, 37.6). The omentum was used for the treatment of brachial plexus injury pain (3 cases), Romberg's disease (1 case), defects of the extremities occurring with chronic obstructive arterial disease (2 cases), posttraumatic...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10130
更新日期:2003-01-01 00:00:00
abstract::The groin flap is one of the most usable flaps. It provides a large amount of skin coverage with an easily concealed donor site. However, when the flap is used to reconstruct areas of the neck, hand, or foot, a secondary procedure for defatting is usually necessary. Thinner flaps are thought to be more useful in these...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2752(1996)17:1<41::AID-MICR8>3.
更新日期:1996-01-01 00:00:00
abstract::The lumbar spines of twenty-one dogs were used as an experimental model. The animals were divided into three groups. In the first group, selective damage to the perimeningeal blood vessels was induced and the resultant hematoma was left untouched in the spinal canal. In the second group, the posterior longitudinal lig...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920130409
更新日期:1992-01-01 00:00:00
abstract::This study entailed direct stereomicroscopic observations of rat abdominal island flaps and the sequence of vascular events that occurred during and after occlusion by clamping of the individual femoral vessels for varying time intervals of up to 16 hours. The vascular changes and the status of the circulation in the ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920040205
更新日期:1983-01-01 00:00:00
abstract::By applying a novel biochemical technique using porcine tendon as the raw material with its antigen minimized, we developed an artificial biological ligament (ABL). We examined and tested its structure, mechanical properties, and biocompatibility and explored the feasibility of reconstructing the anterior cruciate lig...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20442
更新日期:2008-01-01 00:00:00
abstract::Normal myelinated fibers are stained "red" by modified trichrome staining of the frozen section of the nerve. We have used this technique for rapid assessment of the anatomical integrity of the proximal nerve stump by identifying well-preserved myelinated fibers. This technique can also identify degenerating and degen...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920160302
更新日期:1995-01-01 00:00:00
abstract::Free flap reconstruction of the lower back and sacrum is complicated by a paucity of recipient vessels and difficulties in postoperative care. From 1983 to 1997, six patients with intractable wounds of the lower back and sacral area were treated with free flaps. The flaps used were latissimus dorsi (three), combined l...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(sici)1098-2752(2000)20:2<72::aid-micr5>3.
更新日期:2000-01-01 00:00:00
abstract::It is generally known that low-intensity pulsed ultrasound (LIPUS) accelerates peripheral nerve tissue regeneration. However, the precise cellular mechanism involved is still unclear. The purpose of this study was to determine how the Schwann cells respond directly to LIPUS stimuli. Thus, we investigated the effect of...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20644
更新日期:2009-01-01 00:00:00