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Lesion load measurements in multiple sclerosis: the effect of incorporating magnetization transfer contrast in fast-FLAIR sequence.

Abstract：

:We compared the ability and reproducibility of a fast fluid-attenuated inversion recovery (fast-FLAIR) sequence with and without a magnetization transfer (MT) pulse for detecting and measuring multiple sclerosis (MS)-related abnormalities on magnetic resonance imaging (MRI) scans from 20 patients. The Contrast-to-Noise ratios between lesions and normal-appearing white matter, lesion numbers, lesion volumes and the variability of such measurements were similar for the two sequences. This suggests that the addition of MT to FLAIR sequences as currently implemented on standard MRI scanners does not improve the detection of MS lesions.

journal_name

Magn Reson Imaging

journal_title

Magnetic resonance imaging

authors

Filippi M,Rocca MA,Mastronardo G,Comi G

doi

10.1016/s0730-725x(98)00182-9

subject

Has Abstract

pub_date

1999-04-01 00:00:00

pages

459-61

issue

3

eissn

0730-725X

issn

1873-5894

pii

S0730725X98001829

journal_volume

17

pub_type

杂志文章

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