Abstract:
AIM:To investigate the use of Tc-99m tetrofosmin as a breast imaging agent and to compare results of Tc-99m tetrofosmin scintimammography with plain-film mammography and pathological outcome. PATIENTS AND METHODS:Forty-four patients (mean age, 51 years; range 26-79 years) with a palpable breast mass requiring fine needle aspiration biopsy (FNAB) were prospectively studied. All patients had Tc-99m tetrofosmin scintimammography. Patients over 35 years of age had two view mammography performed on the same day. FNAB was performed within 2 weeks of imaging, and patients referred for surgery as appropriate. Results of scintigraphy and plain-film mammography were correlated with pathological outcome. RESULTS:Of the 44 patients, 21 had biopsy proven malignancy while 23 had benign lesions. Of the 21 patients with carcinoma, 20 (95.2%) had positive Tc-99m tetrofosmin scintimammography while 21 (91.3%) of the 23 patients with benign histology had negative scintigraphy. The sensitivity of scintimammography was 95.24%, the specificity was 91.3%, with a positive predictive value of 90.9% and a negative predictive value of 95.45%. Thirty-eight patients had two view mammography performed (six patients were <35 years of age). Of these 38 patients, 21 had biopsy proven malignancy while 17 had benign histology (all patients <35 years of age had benign histology). Of the 21 patients with malignancy, plain-film mammography was suspicious for malignancy in 17 (81%) while four were reported as benign. Of the 17 with benign disease, 14 patients (82.4%) had benign appearances on plain-film mammography while three (18%) had one or more findings suspicious for malignancy. The sensitivity of plain-film mammography in our group was 81%, with a specificity of 82.4%, a positive predictive value of 85% and a negative predictive value of 77.8%. Tc-99m tetrofosmin scintimammography correctly characterized all seven lesions where mammographic evaluation was limited because of dense breast parenchyma or previous surgery and/or radiotherapy. CONCLUSION:Tc-99m tetrofosmin scintimammography is an accurate, well tolerated and non-invasive method of differentiating benign from malignant palpable breast lesions. Negative Tc-99m tetrofosmin scintimammography excludes malignancy with a high degree of confidence while false-positive scintigraphy can occur in cases of proliferative dysplasia and hypercellular fibroadenoma. Tc-99m tetrofosmin scintimammography is particularly useful when plain-film mammography is indeterminate or limited in patients with dense breasts or a history of previous surgery and/or radiotherapy.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Fenlon HM,Phelan N,Tierney S,Gorey T,Ennis JTdoi
10.1016/s0009-9260(98)80028-7subject
Has Abstractpub_date
1998-01-01 00:00:00pages
17-24issue
1eissn
0009-9260issn
1365-229Xjournal_volume
53pub_type
临床试验,杂志文章abstract::Endovascular mechanical thrombectomy (MT) is reserved for acute ischaemic stroke secondary to large vessel occlusion. The various MT techniques employed in the treatment of hyperacute strokes are constantly evolving with new devices and improvisation of existing technology (Wahlgren, et al 2016). In this review, we de...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.10.022
更新日期:2018-05-01 00:00:00
abstract::Morton's 'neuroma' is a painful focus of peri-neural fibrosis, which may affect the interdigital nerves of the feet. Clinical diagnosis and localization may be inaccurate. Computed tomography (CT), ultrasound and magnetic resonance imaging (MRI) have been used to confirm the diagnosis pre-operatively. Recently, MRI us...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0009-9260(97)80305-4
更新日期:1997-01-01 00:00:00
abstract::Pelvic phleboliths were demonstrated in 1000 subjects aged 16--79 years (mean 42.1, s.d. 12.7). They occurred in 44.2% of the subjects, in 37.3% of the males and 50.1% of the females. Among subjects between the ages of 35 and 54, phleboliths occurred more frequently in the females than in the males. In addition the ol...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(80)80095-x
更新日期:1980-01-01 00:00:00
abstract:AIM:To evaluate the diagnostic performance of dual-energy computed tomography (DECT) using the virtual non-calcium (VNCa) technique for the detection of different degrees of vertebral bone marrow oedema. MATERIALS AND METHODS:The present prospective study was approved by the institutional ethics committee. Informed co...
journal_title:Clinical radiology
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doi:10.1016/j.crad.2019.09.143
更新日期:2020-02-01 00:00:00
abstract::A low speed rotational catheter system (ROTACS) was used to recanalize total occlusions of the femoropopliteal artery in two patient groups. In Group A, previous attempts to recanalize the occlusions using standard guidewires and catheters had failed. Group B had undergone no previous attempts at recanalization. The R...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81791-x
更新日期:1994-05-01 00:00:00
abstract:AIM:To determine whether radiographers are able to perform and interpret barium swallows and meals (BSM) to an acceptable standard. MATERIALS AND METHODS:A retrospective audit was performed of all radiographer-managed BSMs over a 4-year period in an acute hospital. Descriptive statistics were used to analyse patient d...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2009.04.008
更新日期:2009-08-01 00:00:00
abstract::Non-tuberculous psoas abscess is associated with a wide variety of conditions in addition to its well known association with infection in the lumbar spine. Computed tomography (CT) enables the diagnosis to be made at a relatively early stage when classical physical signs may be absent. Percutaneous drainage under CT c...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80330-0
更新日期:1986-05-01 00:00:00
abstract::Metastatic spinal cord syndromes usually result from neural compression by adjacent vertebral disease but are occasionally caused by intradural or intramedullary disease. MRI is the most accurate method for evaluation of such syndromes. Knowledge of the relevant imaging appearances and therapeutic options enables the ...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2004.10.011
更新日期:2005-06-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1053/crad.2000.0648
更新日期:2001-04-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80222-8
更新日期:1988-09-01 00:00:00
abstract::Conjugated phenobutiodil (Biliodyl) in the small and large bowel can be recognised by its fine, homogeneous appearance. The findings in 41 patients undergoing oral cholecystography with subsequent clinical follow-up are reported. When the gallbladder fails to opacify on oral cholecystography, the presence of conjugate...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(77)80183-9
更新日期:1977-05-01 00:00:00
abstract::Eighty infants have been treated for neonatal necrotising enterocolitis within a period of five years. Twenty-five per cent developed strictures of the small or large intestine. Four cases of atresia including two with multiple cyst formation were seen. Four patients developed severe malabsorption requiring hyperalime...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(79)80036-7
更新日期:1979-01-01 00:00:00
abstract::A murine monoclonal antibody, H317, specific for placental-type alkaline phosphatase was labelled with 123I and assessed as an imaging agent using a gamma camera computer system in 18 patients suspected of possible recurrent or metastatic ovarian cancer 1-4 years after removal of the primary tumour. Four patterns of d...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80373-7
更新日期:1986-03-01 00:00:00
abstract:AIM:To present the neuroradiological and clinical findings of fourth-ventricular meningiomas to increase awareness of this entity. MATERIALS AND METHODS:The computed tomography (CT; n=5), magnetic resonance imaging (MRI; n=9) features and clinical presentations of 10 patients with pathologically documented fourth-vent...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2011.10.017
更新日期:2012-05-01 00:00:00
abstract::In 20 years we have seen only 78 cases of primary vaginal cancer. 61 patients had squamous carcinoma, three had adenocarcinoma, 10 had clear-cell carcinoma, four of which may have been metastatic from carcinoma of the kidney, and four had malignant melanoma. The actuarial 5-year survival of patients with squamous canc...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80160-x
更新日期:1986-01-01 00:00:00
abstract:AIM:To investigate the diagnostic ability of maximum standardised uptake value (SUVmax) at combined single-photon-emission computed tomography/computed tomography (SPECT/CT) for the evaluation of osteonecrosis of the jaw. MATERIALS AND METHODS:Seven patients with mandibular osteonecrosis (three osteoradionecrosis, thr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2019.05.025
更新日期:2020-01-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2018.02.013
更新日期:2018-07-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2002.0994
更新日期:2002-10-01 00:00:00
abstract::Axial T2-weighted fat-saturated imaging provides information not readily available from routine lumbar spine magnetic resonance imaging (MRI) protocols and routine inclusion of this sequence in place of axial T1-weighted imaging provides additional diagnostic information that can be obtained without increasing examina...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2014.05.006
更新日期:2014-09-01 00:00:00
abstract::Two patients successfully treated for Hodgkin's disease with radiotherapy alone subsequently developed a non-Hodgkin's lymphoma. One patient presented with a pleural effusion and a paraprotein band, the second with recurrent lymphadenopathy. Their case histories are compared with the five others previously reported. F...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80060-5
更新日期:1986-09-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2014.07.015
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2016.03.018
更新日期:2016-10-01 00:00:00
abstract::In a prospective study 59 consecutive outpatients having double-contrast barium enemas (DCBE) were randomised into four groups. Each group had their enema performed at either a 15, 30, 45 or 60 minute interval following the end of a 1.5 litre cleansing water enema. Review of the films by two radiologists demonstrated ...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(05)81695-2
更新日期:1990-05-01 00:00:00
abstract::A case of asymptomatic congenital mediastinal arteriovenous fistula detected in an adult patient is presented. The diagnosis was suspected clinically and confirmed with intravenous digital subtraction angiography. The clinical and radiological features are discussed and the literature reviewed. ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80449-0
更新日期:1992-09-01 00:00:00
abstract::In the absence of abdominal operative procedures, symptomless spontaneous pneumoperitoneum is uncommon. The case is described of a patient with jejunal diverticulosis who developed spontaneous pneumoperitoneum on three occasions and brief details are given of six other cases of jejunal diverticulosis with pneumoperito...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(75)80070-5
更新日期:1975-07-01 00:00:00
abstract:OBJECTIVE:To assess three-dimensional computed tomography 'bronchoscopic' (3-DCTB) reconstruction of routine CT data as a non-invasive method of airway visualization, and compare it with fibreoptic bronchoscopy (FOB). METHODS:Fourteen datasets were acquired from 13 patients undergoing both FOB and CT examination of th...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0009-9260(97)80077-3
更新日期:1997-11-01 00:00:00
abstract::Three-dimensional (3D) computed tomography (CT) reformations were obtained in 15 patients presenting with facial injuries of differing severity. The 3D images were compared with standard radiographs and high resolution CT, including multiplanar reformations, and assessed under the headings of fracture detection, exten...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(87)80144-7
更新日期:1987-09-01 00:00:00
abstract:AIM:To evaluate the role of computed tomography (CT) after herniography in the diagnosis and management of primary and recurrent groin hernias not detectable on clinical examination. MATERIAL AND METHODS:Fifty-one patients underwent CT post-herniography over a 6-year period for suspected primary or recurrent inguinal ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2004.02.013
更新日期:2005-02-01 00:00:00
abstract:AIM:To report the magnetic resonance imaging (MRI) and corresponding histopathological features of squamous cell carcinoma (SCC) originating in the parotid gland. MATERIALS AND METHODS:The MRI images of seven patients with histopathologically proven SCC originating in the parotid gland were reviewed retrospectively, w...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2013.08.002
更新日期:2014-01-01 00:00:00
abstract:AIMS:The aim of this retrospective study was to assess the relative efficacy of plain abdominal radiographs and detailed renal tract ultrasound (US) examination in the diagnosis and follow-up of children with renal tract calculi. METHODS:The records and imaging studies of 28 paediatric patients who had presented with ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2000.0501
更新日期:2000-09-01 00:00:00