Estimation of oncostatin M (OSM) secretion by peritoneal macrophages with regard to the progression of transplantable melanomas.

Abstract:

:The authors have studied the influence of two kinds of transplantable melanomas on the secretion of oncostatin M (OSM) and total proteins by peritoneal macrophages. Culture supernatant samples were tested by ELISA. The macrophages of melanoma-bearing animals released a lower amount of OSM than those of the controls. At the same time the results showed statistically significant increase of protein content in the supernatants of cultured macrophages from melanoma-bearing hamsters in comparison with the controls. However, it has not been possible to demonstrate any relationship between melanoma progression and changes in the secretion of OSM by peritoneal macrophages.

journal_name

Neoplasma

journal_title

Neoplasma

authors

Kozłowska K,Cichorek M,Zarzeczna M

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

369-72

issue

6

eissn

0028-2685

issn

1338-4317

journal_volume

45

pub_type

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