Removal of extracerebral tissues in dual-echo magnetic resonance images via linear scale-space features.


:The location and masking of the brain and surrounding cerebrospinal fluid (CSF) in two-dimensional (2D) dual-echo fast spin-echo (FSE) magnetic resonance (MR) images of the head is achieved by an automated procedure with a voxel-based computational algorithm. Linear scale-space features are derived from the short-echo, proton-density (PD)-weighted images. The second-order Gaussian derivative (the Laplacian) operator is applied at three different spatial scales as a measure of image convexity/concavity with a first-order Gaussian derivative measure (the squared gradient) at a single scale used to circumscribe cortical regions. A mask obtained from the long-echo, T2-weighted image is used to remove extracerebral components of the visual system. A three-dimensional (3D) connectivity analysis then identifies the largest connected volume as the brain. Five dual-echo fast spin-echo images acquired by repeated scanning of the same normal volunteer were used to verify reproducibility; and coronal and axial acquisitions from another normal volunteer to demonstrate the method's robustness to data collected with non-cubic voxels. Images acquired from five individuals with Alzheimer's disease are also presented to show that the algorithm can be used in cases of non-normative anatomy. Validity is affirmed by demonstrating that cerebral volumes estimated by this method for all 12 images are highly correlated (R = 0.98) with estimates obtained by an expert human operator.


Magn Reson Imaging


Suckling J,Brammer MJ,Lingford-Hughes A,Bullmore ET




Has Abstract


1999-02-01 00:00:00














  • Diffusion-weighted MRI and MR- volumetry--in the evaluation of tumor response after preoperative chemoradiotherapy in patients with locally advanced rectal cancer.

    abstract:PURPOSE:To determine the diagnostic performance of diffusion-weighted MRI and MR volumetry for the assessment of tumor response after preoperative chemoradiotherapy (CRT) in patients with locally advanced rectal cancer. MATERIALS AND METHODS:Forty-three patients with rectal cancer who underwent preoperative CRT were p...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Birlik B,Obuz F,Elibol FD,Celik AO,Sokmen S,Terzi C,Sagol O,Sarioglu S,Gorken I,Oztop I

    更新日期:2015-02-01 00:00:00

  • Pulseq-Graphical Programming Interface: Open source visual environment for prototyping pulse sequences and integrated magnetic resonance imaging algorithm development.

    abstract:PURPOSE:To provide a single open-source platform for comprehensive MR algorithm development inclusive of simulations, pulse sequence design and deployment, reconstruction, and image analysis. METHODS:We integrated the "Pulseq" platform for vendor-independent pulse programming with Graphical Programming Interface (GPI)...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Ravi KS,Potdar S,Poojar P,Reddy AK,Kroboth S,Nielsen JF,Zaitsev M,Venkatesan R,Geethanath S

    更新日期:2018-10-01 00:00:00

  • Flexible, phase-matched, linear receive arrays for high-field MRI in monkeys.

    abstract::High signal-to-noise ratios (SNR) are essential for high-resolution anatomical and functional MRI. Phased arrays are advantageous for this but have the drawback that they often have inflexible and bulky configurations. Particularly in experiments where functional MRI is combined with simultaneous electrophysiology, sp...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Goense J,Logothetis NK,Merkle H

    更新日期:2010-10-01 00:00:00

  • A simulation-based comparison of two methods for determining relaxation rates from relaxometry images.

    abstract::When assessing liver iron content using relaxometry, an average relaxation rate (R1, R2 or R2*) is usually determined from a region of interest or the entire liver. This is commonly performed by fitting the signal decay in individual voxels to an appropriate relaxation function. The voxel-level parameters resulting fr...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Marro K,Otto R,Kolokythas O,Shimamura A,Sanders JE,McDonald GB,Friedman SD

    更新日期:2011-05-01 00:00:00

  • Evaluation of EPI distortion correction methods for quantitative MRI of the brain at high magnetic field.

    abstract::High field MRI has been applied to high-resolution structural and functional imaging of the brain. Echo planar imaging (EPI) is an ultrafast acquisition technique widely used in diffusion imaging, functional MRI and perfusion imaging. However, it suffers from geometric and intensity distortions caused by static magnet...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Hong X,To XV,Teh I,Soh JR,Chuang KH

    更新日期:2015-11-01 00:00:00

  • Analyzing spatially and temporally visualized formation behavior of methane hydrate in unconsolidated porous media.

    abstract::An understanding of the nucleation and growth mechanism of methane hydrate in porous space is essential for exploitation and application of hydrates, but the mechanism is yet to be clarified. Magnetic resonance imaging (MRI) was employed to visually analyze the spatial and temporal formation behavior of methane hydrat...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Zhang L,Sun L,Sun M,Lv X,Dong H,Miao Y,Yang L,Song Y,Zhao J

    更新日期:2019-09-01 00:00:00

  • Magnetic resonance spectroscopy of the brain in neurologically asymptomatic HIV-infected patients.

    abstract::The CNS involvement is frequently found in human immunodeficiency virus (HIV) infection. The purpose of our study was to determine whether proton magnetic resonance spectroscopy (MRS) could detect early brain involvement in neurologically asymptomatic HIV-infected patients with normal MR imagings and to find the corre...

    journal_title:Magnetic resonance imaging

    pub_type: 临床试验,杂志文章


    authors: Suwanwelaa N,Phanuphak P,Phanthumchinda K,Suwanwela NC,Tantivatana J,Ruxrungtham K,Suttipan J,Wangsuphachart S,Hanvanich M

    更新日期:2000-09-01 00:00:00

  • Synthesis of magnetic gradients for NMR tomography.

    abstract::A numerical method is applied to calculate an optimal distribution of currents in air which generate the magnetic field gradients required to spatially encode the radiofrequency signal in a NMR tomographic experiment. We compare the performances of the gradient circuits for the whole body air-core electromagnet descri...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Mustarelli P,Rudnicki M,Savini A,Savoldi F,Villa M

    更新日期:1990-01-01 00:00:00

  • Rapid whole-brain quantitative magnetization transfer imaging using 3D selective inversion recovery sequences.

    abstract::Selective inversion recovery (SIR) is a quantitative magnetization transfer (qMT) method that provides estimates of parameters related to myelin content in white matter, namely the macromolecular pool-size-ratio (PSR) and the spin-lattice relaxation rate of the free pool (R1f), without the need for independent estimat...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Cronin MJ,Xu J,Bagnato F,Gochberg DF,Gore JC,Dortch RD

    更新日期:2020-05-01 00:00:00

  • 1H magnetic resonance imaging and 31P magnetic resonance spectroscopy in experimental filariasis.

    abstract::1H Magnetic resonance imaging and 31P magnetic resonance spectroscopy (MRS) have been carried out in experimental rodent filariasis, i.e., Acanthocheilonema viteae infection in the rodent host, Mastomys coucha. The T2-weighted image of the infected host shows fine hyperintense thread like structures of adult filariid ...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Shukla-Dave A,Fatma N,Roy R,Srivastava S,Chatterjee RK,Govindaraju V,Viswanathan AK,Raghunathan P

    更新日期:1997-01-01 00:00:00

  • Assessment of extravascular extracellular space fraction in human melanoma xenografts by DCE-MRI and kinetic modeling.

    abstract::Tumor aggressiveness and response to therapy are influenced by the extravascular extracellular space fraction (EESF) of the malignant tissue. The EESF may, therefore, be an important prognostic parameter for cancer patients. The aim of this study was to investigate whether gadopentetate dimeglumine (Gd-DTPA)-based dyn...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Benjaminsen IC,Brurberg KG,Ruud EB,Rofstad EK

    更新日期:2008-02-01 00:00:00

  • Surface coil imaging of rat spine at 7.0 T.

    abstract::An inductively coupled surface coil for imaging the rat spine at 7 T is described. This planar circular probe was made from microwave substrate to limit the size of the coil and to minimize the magnetic susceptibility. The surface coil was used as a single transmit/receive coil and as a receive-only coil with a birdca...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Banson ML,Cofer GP,Hedlund LW,Johnson GA

    更新日期:1992-01-01 00:00:00

  • Off-resonance binomial preparatory pulse technique for high sensitivity MRI of H2O17.

    abstract::H2O17 is a freely diffusible tracer and naturally occurring isotope of O16 detectable by MRI and has been shown to be useful for assessing cerebral perfusion in animal studies using direct and indirect MR detection techniques. However, earlier MR techniques are either not sensitive to changes in small concentrations o...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Sood R

    更新日期:2004-02-01 00:00:00

  • Effects of 3D sampling in (k, t)-space on temporal qualities of dynamic MRI.

    abstract::3D (kx, ky, t)-space analysis is invoked to provide insights into dynamic magnetic resonance imaging (DMRI) with arbitrary k-space sampling trajectories. The effects of 3D sampling in (kx, ky, t) are analyzed theoretically and verified with computer simulation. The analyses show that a 3D sampling pattern that is more...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Park JB,Nishimura DG

    更新日期:2006-10-01 00:00:00

  • Mri measurements of T1, T2 and D for gels undergoing volume phase transition.

    abstract::Gels consist of crosslinked polymer network swollen in solvent. The network of flexible long-chain molecules traps the liquid medium they are immersed in. Some gels undergo abrupt volume change, a phase transition process, by swelling-shrinking in response to external stimuli changes in solvent composition, temperatur...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Yung KT

    更新日期:2003-02-01 00:00:00

  • Correction of partial volume inaccuracies in quantitative phase contrast MR angiography.

    abstract::The phase difference method of phase contrast MR angiography provides a means of measuring the average velocity in each voxel of an MR scan. When static tissue is present in a voxel containing flow, the measured velocity is not the average velocity of the flow alone, but is lower due to the partial volume effect of th...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Hamilton CA

    更新日期:1994-01-01 00:00:00

  • Voxel- and atlas-based analysis of diffusion tensor imaging may reveal focal axonal injuries in mild traumatic brain injury -- comparison with diffuse axonal injury.

    abstract:BACKGROUND:The diagnosis and management of mild traumatic brain injury (MTBI) continue to be subjects of debate, with varying opinions regarding the extent to which tissue-based impairments versus the impacts of other stressors cause ongoing disability. Detecting areas of the brain with abnormalities that can explain s...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Kasahara K,Hashimoto K,Abo M,Senoo A

    更新日期:2012-05-01 00:00:00

  • Differentiation of hepatomas from nonhepatomatous masses: use of MnDPDP-enhanced MR images.

    abstract::Manganese (II) N,N'-dipyridoxylethylenediamine-N,N' diacetate 5,5'-bis(phosphate) (MnDPDP) is a hepatobiliary agent that is incorporated into the hepatocyte. We retrospectively reviewed our experience with 39 focal liver lesions in 20 patients studies with MnDPDP-enhanced hepatic magnetic resonance (MR) imaging to det...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Liou J,Lee JK,Borrello JA,Brown JJ

    更新日期:1994-01-01 00:00:00

  • An MRI perfusion model incorporating nonequilibrium exchange between vascular and extravascular compartments.

    abstract::A model of MRI signal intensity which is a function of perfusion is developed based upon the assumption that biological tissue can be represented by a blood and tissue compartment. The longitudinal magnetization is derived from the Bloch equations which are modified to model the magnetization in both the blood and tis...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Gullberg GT,Ma X,Parker DL,Roy DN

    更新日期:1991-01-01 00:00:00

  • Data-driven curvilinear reconstructions of 3D MR images: application to cryptogenic extratemporal epilepsy.

    abstract::This paper presents a data-driven method for the reconstruction and visualisation of curvilinear slices from three-dimensional (3D) magnetic resonance (MR) scans of the head. Visualisation of curvilinear slices, rather than standard planar slices, produces symmetrical views of the cortex and allows small abnormalities...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Musse O,Armspach JP,Namer IJ,Heitz F,Hennel F,Grucker D

    更新日期:1998-12-01 00:00:00

  • Comparison between end-tidal CO₂ and respiration volume per time for detecting BOLD signal fluctuations during paced hyperventilation.

    abstract::Respiratory motion and capnometry monitoring were performed during blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) of the brain while a series of paced hyperventilation tasks were performed that caused significant hypocapnia. Respiration volume per time (RVT) and end-tidal carbon dioxi...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Vogt KM,Ibinson JW,Schmalbrock P,Small RH

    更新日期:2011-11-01 00:00:00

  • MR visible localization device for radiographic-pathologic correlation of surgical specimens.

    abstract:PURPOSE:The detection of small parenchymal hepatic lesions identified by preoperative imaging remains a challenge for traditional pathologic methods in large specimens. We developed a magnetic resonance imaging (MRI) compatible localization device for imaging of surgical specimens aimed to improve identification and lo...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Kinner S,Schubert TB,Nocerino EA,Hynes S,Colgan TJ,Loeffler AG,Brace C,Reeder SB,Winslow E

    更新日期:2017-04-01 00:00:00

  • Sampling time effects on signal-to-noise and contrast-to-noise ratios in spin-echo MRI.

    abstract::This work discusses the effect of sampling time on noise, signal-to-noise and contrast-to-noise ratios in magnetic resonance imaging. A simple imaging experiment is performed to demonstrate the effect of sampling time on noise, confirming theoretical expectations that doubling the sampling time while decreasing the re...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Hendrick RE

    更新日期:1987-01-01 00:00:00

  • Undifferentiated (embryonal) sarcoma of the liver (USL): MRI findings including dynamic gadolinium enhancement.

    abstract::We report the MR appearance of undifferentiated (embryonal) sarcoma of the liver (USL) in a 13-year-old female who presented with a 1-year history of intermittent abdominal pain, weight loss, and fatigue. The tumor was a large, solitary, well-defined focal mass lesion with multiple cystic spaces, septations, and subst...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Psatha EA,Semelka RC,Fordham L,Firat Z,Woosley JT

    更新日期:2004-07-01 00:00:00

  • Application of fuzzy c-means segmentation technique for tissue differentiation in MR images of a hemorrhagic glioblastoma multiforme.

    abstract::The application of a raw data-based, operator-independent MR segmentation technique to differentiate boundaries of tumor from edema or hemorrhage is demonstrated. A case of a glioblastoma multiforme with gross and histopathologic correlation is presented. The MR image data set was segmented into tissue classes based o...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Phillips WE 2nd,Velthuizen RP,Phuphanich S,Hall LO,Clarke LP,Silbiger ML

    更新日期:1995-01-01 00:00:00

  • SSFP fMRI at 3 tesla: Efficiency of polar acquisition-reconstruction technique.

    abstract::SSFP-based fMRI techniques, known for their high specificity and low geometrical distortion, look promising for high-resolution brain mapping. Nevertheless, they suffer from lack of speed and sensitivity, leading them to be exploited mostly in high-field scanners. Radial acquisition can help with these inefficiencies ...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Malekian V,Rastegar F,Shafieizargar B,Nasiraei-Moghaddam A

    更新日期:2020-12-01 00:00:00

  • In vivo field dependence of proton relaxation times in human brain, liver and skeletal muscle: a multicenter study.

    abstract::T1 and T2 relaxation times are fundamental parameters for signal contrast behaviour in MRI. A number of ex vivo relaxometry studies have dealt with the magnetic field dispersion of T1. By means of multicenter study within the frame of the COMAC BME Concerted Action on Tissue Characterization by MRI and MRS, the in viv...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章,多中心研究


    authors: Henriksen O,de Certaines JD,Spisni A,Cortsen M,Muller RN,Ring PB

    更新日期:1993-01-01 00:00:00

  • Combination of integrated dynamic shimming and readout-segmented echo planar imaging for diffusion weighted MRI of the head and neck region at 3Tesla.

    abstract:PURPOSE:To evaluate the performance of combined integrated slice-by-slice shimming and readout-segmented EPI (irsEPI) for diffusion-weighted MR imaging (DWI) of the neck at 3Tesla. METHODS:This study was approved by the local ethics committee. An anthropometric phantom of the head/neck region incorporating compartment...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Walter SS,Liu W,Stemmer A,Martirosian P,Nikolaou K,Notohamiprodjo M,Gatidis S

    更新日期:2017-10-01 00:00:00

  • A new method for diffusion weighted imaging.

    abstract::A new method for generating diffusion contrast in magnetic resonance imaging is presented. This technique is robust enough to allow implementation on conventional imaging systems without hardware modifications. Results from phantom measurements are reported. Qualitative contrast changes in magnetic resonance images de...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Norwood TJ,Williams SC

    更新日期:1993-01-01 00:00:00

  • Changes in the liver parenchyma after proton beam radiotherapy: evaluation with MR imaging.

    abstract::The objective of this study was to describe magnetic resonance (MR) findings with a 1.5T imager for hepatic parenchymal changes after proton beam radiotherapy. Thirty-two patients who received proton radiotherapy with doses of 50-87 Gy underwent MR imaging 1-75 months (mean 22 months) after the start of irradiation. A...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章


    authors: Onaya H,Itai Y,Yoshioka H,Ahmadi T,Niitsu M,Okumura T,Akine Y,Matsuzaki Y,Doi M,Tsuji H,Tsujii H

    更新日期:2000-07-01 00:00:00