Synergistic in vitro antimalarial activity of omeprazole and quinine.

Abstract:

:Previous studies have shown that the proton pump inhibitor omeprazole has antimalarial activity in vitro. The interactions of omeprazole with commonly used antimalarial drugs were assessed in vitro. Omeprazole and quinine combinations were synergistic; however, chloroquine and omeprazole combinations were antagonistic. Artemisinin drugs had additive antimalarial activities with omeprazole.

authors

Skinner-Adams T,Davis TM

doi

10.1128/AAC.43.5.1304

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

1304-6

issue

5

eissn

0066-4804

issn

1098-6596

journal_volume

43

pub_type

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