Genetic evidence that Notch affects independently the development of machrochaeta and wing venation in Drosophila melanogaster.

Abstract:

:Temperature sensitive experiments on the interaction of Abruptex mutations of the Notch locus and Enhancer of split indicate that the effect of temperature on the development of macrochaeta and wing venation is different. This suggest that Notch affects the development of macrochaeta and wing venation in different and independent ways being in accordance with the proposition that the signal pathway from the Notch receptor at the cell membrane to Enhancer of split complex in the nucleus is different in the case of the development of macrochaeta and wing venation. The Abruptex mutations as gain-of-function mutations of the Notch locus cannot rescue the Enhancer of split phenotype.

journal_name

Hereditas

journal_title

Hereditas

authors

Grushko T,Rantanen M,Portin P

doi

10.1111/j.1601-5223.1998.t01-1-00251.x

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

251-7

issue

3

eissn

0018-0661

issn

1601-5223

journal_volume

129

pub_type

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