Transplantation of pancreatic islets contained in minimal volume microcapsules in diabetic high mammalians.

abstract：:Over the last years, El Sistema--the Venezuelan project started in 1975 and now acknowledged worldwide as the most significant example of collective music education--has inspired a profusion of remarkable initiatives on all continents. From the original impulse by founder José Antonio Abreu, strong social principles o...

journal_title：Annals of the New York Academy of Sciences

authors： Majno M

更新日期：2012-04-01 00:00:00

abstract：:Investigations of the I-Ek-restricted, cytochrome c-specific T-cell response in mice show that both T-cell receptor V alpha and V beta CDR3 residues and the use of particular V alpha s and V beta s are necessary for recognition. Data strongly suggest that specific CDR3 residues are important in contacting the peptide....

journal_title：Annals of the New York Academy of Sciences

authors： Davis MM,McHeyzer-Williams M,Chien YH

更新日期：1995-07-07 00:00:00

abstract：:The development of an integrated system for the continuous, automated production of pure cell culture derived proteins is discussed. The system comprises a cell culture subunit for the continuous culture of mammalian cells and a purification subunit linked on-line to the cell culture subunit. The cells are compartment...

journal_title：Annals of the New York Academy of Sciences

authors： Grandics P,Szathmary S,Szathmary Z,O'Neill T

更新日期：1991-12-27 00:00:00

abstract：:Classic studies of the cerebellum before the middle of the twentieth century established the structural entity of the cerebellum and characterized its function as enabling animals and humans to carry out smooth and accurate movements, even at a high speed and without visual feedback. In the 1960s, neuronal circuit str...

journal_title：Annals of the New York Academy of Sciences

authors： Ito M

更新日期：2002-12-01 00:00:00

abstract：:To develop new treatments for beta-thalassemia, it is essential to identify the genes involved in the relevant pathophysiological processes. Iron metabolism in thalassemia mice being investigated, focusing on the expression of a gene called hepcidin (Hamp), which is expressed in the liver and whose product (Hamp) is s...

journal_title：Annals of the New York Academy of Sciences

authors： Breda L,Gardenghi S,Guy E,Rachmilewitz EA,Weizer-Stern O,Adamsky K,Amariglio N,Rechavi G,Giardina PJ,Grady RW,Rivella S

更新日期：2005-01-01 00:00:00

abstract：:Anti-inflammatory efficacy of the fermented wheat germ extract (FWGE, Avemar) in the rat adjuvant arthritis (AA) model was examined. To Wistar rats with AA, different doses of FWGE and anti-inflammatory drugs (indomethacin, dexamethasone) as monotherapies were administered and FWGE and either diclofenac or dexamethaso...

journal_title：Annals of the New York Academy of Sciences

authors： Telekes A,Resetar A,Balint G,Blazso G,Falkay G,Lapis K,Raso E,Szende B,Ehrenfeld M,Shoenfeld Y,Hidvegi M

更新日期：2007-09-01 00:00:00

abstract：:In this note epistemological problems in general theories about living systems are considered; in particular, the question of hidden connections between different areas of experience, such as folk biology and scientific biology, and hidden connections between central concepts of theoretical biology, such as function, ...

journal_title：Annals of the New York Academy of Sciences

authors： Emmeche C

更新日期：2000-01-01 00:00:00

abstract：:These data suggest that shock stress during adolescence increases ETOH consumption and may contribute to an increase in aggression in early adulthood. Interestingly, shock stress without ETOH results in timid behavior in early adulthood. One might speculate that adolescent hamsters "self-medicate" to deal with continu...

journal_title：Annals of the New York Academy of Sciences

authors： Ferris CF,Brewer J

更新日期：1996-09-20 00:00:00

abstract：:Human female reproductive aging consists of multiple processes and interacts with other physiological systems in unique ways. Here we discuss eight recent longitudinal, epidemiologic studies of female reproductive aging that include endocrine data to highlight their contributions to our understanding of these various ...

journal_title：Annals of the New York Academy of Sciences

authors： Ferrell RJ,Sowers M

更新日期：2010-08-01 00:00:00

abstract：:Air particulate activity over all of the Northern Hemisphere reached its highest levels since the termination of nuclear weapons testing--sometimes up to 1 million times higher than before the Chernobyl contamination. There were essential changes in the ionic, aerosol, and gas structure of the surface air in the heavi...

journal_title：Annals of the New York Academy of Sciences

authors： Yablokov AV,Nesterenko VB,Nesterenko AV

更新日期：2009-11-01 00:00:00

abstract：:The avoidance of autoimmunity requires mechanisms to actively silence or tolerize self reactive T cells in the periphery. During infection, dendritic cells are not only capturing microbial antigens, but also are processing self antigens from dying cells as well as innocuous environmental proteins. Since the dendritic ...

journal_title：Annals of the New York Academy of Sciences

authors： Steinman RM,Hawiger D,Liu K,Bonifaz L,Bonnyay D,Mahnke K,Iyoda T,Ravetch J,Dhodapkar M,Inaba K,Nussenzweig M

更新日期：2003-04-01 00:00:00

abstract：:The present study was aimed at finding neural correlates of aesthetic versus descriptive listening of the same musical cadences. Results showed that aesthetic listening generated greater right frontocentral negativities than did descriptive listening, indicating distinct cortical mechanisms for aesthetic versus descri...

journal_title：Annals of the New York Academy of Sciences

authors： Brattico E,Jacobsen T,De Baene W,Nakai N,Tervaniemi M

更新日期：2003-11-01 00:00:00

abstract：:Tick-borne pathogens in the genus Ehrlichia cause emerging zoonoses. Although laboratory mice are susceptible to Ehrlichia infections, many isolates do not cause clinical illness. In contrast, the Ixodes ovatus Ehrlichia-like agent (IOE) causes disease and immune responses in mice comparable to the human illness cause...

journal_title：Annals of the New York Academy of Sciences

authors： Munderloh UG,Silverman DJ,MacNamara KC,Ahlstrand GG,Chatterjee M,Winslow GM

更新日期：2009-05-01 00:00:00

abstract：:A fraction with lymphokine properties was isolated from supernatant medium of the continuous cultured human lymphoblast cell line, 1788. Culture medium containing 2% human serum was used for cell growth in order to minimize antigenicity of supernatant fractions isolated from the medium. The culture medium was passed t...

journal_title：Annals of the New York Academy of Sciences

authors： Papermaster BW,Holtermann OA,McDaniel MC,Klein E,Djerassi I,Rosner D,Dao T,Costanzi JJ

更新日期：1976-01-01 00:00:00

abstract：:As illustrated in Figure 1, a disturbance of the intracellular Ca2+ homeostasis is thought to be a common pathogenic factor for the generation of secondary nerve cell damage that develops after brain trauma or stroke or during the course of neurodegenerative diseases. A neuronal Ca2+ overload which may result from an ...

journal_title：Annals of the New York Academy of Sciences

authors： Schubert P,Ogata T,Marchini C,Ferroni S,Rudolphi K

更新日期：1997-10-15 00:00:00

abstract：:The layered peptide array (LPA) is a recently developed technique designed to measure antibody levels in a multiplex, high-throughput manner. LPAs can assess antibody presence either in fluid samples or from tissues while maintaining the two-dimensional orientation of the life science platform. In this manuscript, we ...

journal_title：Annals of the New York Academy of Sciences

authors： Gannot G,Tangrea MA,Chuaqui RF,Gillespie JW,Emmert-Buck MR

更新日期：2007-03-01 00:00:00

abstract：:Rats inoculated once with nicotinic acetylcholine receptor and adjuvants had two episodes of weakness, the first being acute and transient, starting on day 8, and remitting in a few days, the second, chronic, progressive, and appearing after day 20. In the acute phase, the compound action potential and twitch evoked ...

journal_title：Annals of the New York Academy of Sciences

authors： Lambert EH,Lindstrom JM,Lennon VA

更新日期：1976-01-01 00:00:00

abstract：:The rapid, inexpensive transmission of words and data, brought about by the internet and cheap computers, is changing the world faster than anything mankind has ever experienced, reaching into nearly every aspect of our lives, public and private, commercial and governmental. We are in an Information Age with an essent...

journal_title：Annals of the New York Academy of Sciences

authors： Hugh-Jones M

更新日期：2000-01-01 00:00:00

abstract：:The following on molecular aspects of esophageal development contains commentaries on esophageal striated myogenesis and transdifferentiation; conversion from columnar into stratified squamous epithelium in the mouse esophagus; the roles for BMP signaling in the developing esophagus and forestomach; and evidence of a ...

journal_title：Annals of the New York Academy of Sciences

authors： Rishniw M,Rodriguez P,Que J,Burke ZD,Tosh D,Chen H,Chen X

更新日期：2011-09-01 00:00:00

abstract：:Aging may pose a challenge to the central nervous system, increasing its susceptibility to apoptotic events. Recent findings indicate that caloric restriction (CR) may have a profound effect on brain function and vulnerability to injury and diseases, by enhancing neuroprotection, stimulating the production of new neur...

journal_title：Annals of the New York Academy of Sciences

authors： Hiona A,Leeuwenburgh C

更新日期：2004-06-01 00:00:00

abstract：:This has been an overview of fish health, a comparison of some aspects of fish husbandry with other animal husbandry, and comments concerning fish health research--especially where it is going. The 1972 disease survey identified current problems; it ranked the problems according to priority. More important, research e...

journal_title：Annals of the New York Academy of Sciences

authors： Wolf K

更新日期：1975-01-24 00:00:00

abstract：:Homogenate of 30 sarcoid lymph nodes was injected into the footpads of mice and 42% of the mice showed epitheloid-cell granulomas in the sites. However, the control lymph-node homogenates obtained from nonsarcoid patients also provoked similar granulomatous changes, although the positive rate was somewhat lower. In th...

journal_title：Annals of the New York Academy of Sciences

authors： Iwai K,Takahashi S

更新日期：1976-01-01 00:00:00

abstract：:Genome architecture is well diversified among eukaryotes in terms of size and content, with many being radically shaped by ancient and ongoing genome conflicts with transposable elements (e.g., the large transposon-rich genomes common among plants). In ciliates, a group of microbial eukaryotes with distinct somatic an...

journal_title：Annals of the New York Academy of Sciences

authors： Maurer-Alcalá XX,Nowacki M

更新日期：2019-07-01 00:00:00

abstract：:Based upon their migrating properties and effector functions, CD8(+) T cells have been further classified into central memory (T(CM)) and two types of effector memory (T(EM) and T(EMRA)) cells. These memory cells display distinct replicative characteristics. Because apoptosis plays an important role in cellular homeos...

journal_title：Annals of the New York Academy of Sciences

authors： Gupta S,Gollapudi S

更新日期：2007-08-01 00:00:00

abstract：:Most chemical contaminants occur in highest concentrations in coastal waters, often maximized in very localized areas. In general, this situation represents the exposure pattern for marine animals. However, the availability of contaminant to an organism depends not only on its concentration but also on its chemical na...

journal_title：Annals of the New York Academy of Sciences

authors： Whittle KJ,Hardy R,Holden AV,Johnston R,Pentreath RJ

更新日期：1978-09-29 00:00:00

abstract：:We found a novel genetic abnormality, heterozygous C-->T nucleotide substitution at position -1138 bp in the 5'-flanking region of the fibrinogen A alpha gene, in patients with hypofibrinogenemia. Luciferase reporter assay using the pGL3-basic vector and CHO cells indicates that the transcriptional activity of a vecto...

journal_title：Annals of the New York Academy of Sciences

authors： Okumura N,Terasawa F,Yonekawa O,Hamada E,Kaneko H

更新日期：2001-01-01 00:00:00

abstract：:Experimental and observational findings suggest that calcium intake may protect against colorectal neoplasia. To investigate this hypothesis, we conducted a randomized, double-blind trial of colorectal adenoma recurrence. Nine hundred thirty patients with a recent history of colorectal adenomas were randomly given cal...

journal_title：Annals of the New York Academy of Sciences

authors： Baron JA,Beach M,Mandel JS,van Stolk RU,Haile RW,Sandler RS,Rothstein R,Summers RW,Snover DC,Beck GJ,Frankl H,Pearson L,Bond JH,Greenberg ER

更新日期：1999-01-01 00:00:00

abstract：:Release of the amyloid precursor protein (APP) of Alzheimer's disease from Swiss 3T3 fibroblasts was stimulated in a concentration-dependent manner by phorbol 12-myristate 13-acetate. In fibroblasts overexpressing protein kinase C alpha (PKC alpha), the EC50 for this response was 7 nM, while in control cells the EC50 ...

journal_title：Annals of the New York Academy of Sciences

authors： Slack BE,Nitsch RM,Livneh E,Kunz GM Jr,Eldar H,Wurtman RJ

更新日期：1993-09-24 00:00:00

abstract：:Force and shortening in striated muscle are driven by a structural working stroke in the globular portion of the myosin molecules-the myosin head-that cross-links the myosin-containing filaments and the actin-containing filaments. We use time-resolved X-ray diffraction in single fibers from frog skeletal muscle to lin...

journal_title：Annals of the New York Academy of Sciences

authors： Reconditi M,Linari M,Lucii L,Stewart A,Sun YB,Narayanan T,Irving T,Piazzesi G,Irving M,Lombardi V

更新日期：2005-06-01 00:00:00

abstract：:Sex differences in social behavior are center stage in recent formulations of evolutionary psychology. Evolutionary psychology, with its emphasis on the long-term consequences of early adaptations, offers itself as an alternative meta-theory to mainstream social psychology, which emphasizes the importance of social st...

journal_title：Annals of the New York Academy of Sciences

authors： Rabinowitz VC,Valian V

更新日期：2000-04-01 00:00:00