Characterization of adrenergic receptors in the accessory lacrimal glands of the upper eyelid.

Abstract:

PURPOSE:To identify the histologic location as well as the exact subtype of adrenergic receptors in the accessory lacrimal glands of the upper eyelid. METHODS:Upper eyelid specimens were collected from 19 patients undergoing routine blepharoptosis correction via a posterior tarsoconjunctival mullerectomy. Immunohistochemical staining using polyclonal antibodies against human alpha 1, alpha 2, beta 1, and beta 2 receptors was performed on all specimens. RESULTS:beta 1 receptors were the predominant adrenergic receptor subtype in the glands of Wolfring. CONCLUSIONS:The presence of beta 1 receptors in the accessory lacrimal glands of the upper eyelid may suggest a possible role for selective beta 1 agonists in the treatment of keratitis sicca.

authors

Esmaeli-Gutstein B,Hewlett BR,Harvey JT

doi

10.1097/00002341-199907000-00005

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

245-51

issue

4

eissn

0740-9303

issn

1537-2677

journal_volume

15

pub_type

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