Abstract:
:A retrospective study of 45 patients with low-tension glaucoma revealed the mean age at diagnosis to be 66 years. Seventeen patients had follow-up visual field examinations, the average follow-up period being 6.4 years. There was no significant difference in prognosis of the ocular course between patients with Po/C equal to or greater than 100 and those with Po/C less than 100. The presence of splinter hemorrhages at the optic disk (10% of affected eyes) or of systemic arterial hypertension (diastolic blood pressure greater than 100 mm Hg) was associated with progression of visual field defects. Patients with sudden visual loss or associated hemodynamic events (33% of the total patients) had a more favorable prognosis regarding stability (lack of progression) of visual field defects than those without such an event. Extension of visual field defects across the macula was a common finding (25% of affected eyes). No firm evidence was obtained to indicate that treatment of the low-tension glaucoma improved the prognosis of the ocular course.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Chumbley LC,Brubaker RFdoi
10.1016/0002-9394(76)90359-7subject
Has Abstractpub_date
1976-06-01 00:00:00pages
761-7issue
6eissn
0002-9394issn
1879-1891pii
0002-9394(76)90359-7journal_volume
81pub_type
杂志文章abstract:PURPOSE:To determine whether cataract in patients with atopic dermatitis is associated with higher levels of aqueous flare or cells. METHODS:In a prospective study, 35 consecutive patients examined during a 6-month period at the atopic dermatitis service in a university hospital underwent standardized ophthalmologic e...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71641-1
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:We performed a histopathologic and immunohistologic study to determine the macromolecular and cellular components of subfoveal neovascular membranes removed at the time of submacular surgery. METHODS:Subfoveal neovascular membranes were surgically removed from ten patients (seven with age-related macular degen...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72158-0
更新日期:1995-09-01 00:00:00
abstract:PURPOSE:To report microvascular retinopathy after percutaneous transluminal coronary angioplasty and stent insertion for acute myocardial infarction. DESIGN:Observational case series. METHODS:Retrospective review of seven patients with a retinal microangiopathy following coronary catheterization, angioplasty, and ste...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00267-8
更新日期:2003-09-01 00:00:00
abstract:PURPOSE:To determine whether ocular phenotypic features of keratoconjunctivitis sicca (KCS) and/or participant-reported symptoms of dry eye disease are associated with depression in women participants enrolled in the Sjögren's International Collaborative Clinical Alliance (SICCA). DESIGN:Cross-sectional study. METHOD...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2018.04.004
更新日期:2018-07-01 00:00:00
abstract::Three cases of bacterial endophthalmitis following corneal transplantation resulted from suture abscesses that were initiated by loose or broken exposed sutures. Histopathologic examination clearly demonstrated that the infection gained access to the anterior chamber by following a deeply placed suture that traversed ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(85)90217-x
更新日期:1985-02-15 00:00:00
abstract::Thirty-six patients who had clinically progressive Graves' dysthyroid orbitopathy were treated with supervoltage orbital radiotherapy. Twenty-three of the patients had discontinued the use of orally administered prednisone after developing intolerable side effects. Medical contraindications prevented seven patients fr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)76158-6
更新日期:1992-04-15 00:00:00
abstract:PURPOSE:To report unusual fundus findings in two cases of melanoma-associated retinopathy. METHODS:Observational case reports. The histories of two patients with melanoma-associated retinopathy were reviewed. Sera from both patients were examined for antibodies against retinal bipolar cells. Immunofluorescence was per...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)00915-1
更新日期:2001-08-01 00:00:00
abstract:PURPOSE:To report an uncommon case of multifocal choroiditis as the result of disseminated Cryptococcus neoformans infection in a patient who is HIV-positive. DESIGN:Interventional case report. METHODS:A 27-year-old HIV-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.03.024
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:To describe the incidence of vision loss and of ocular complications attributable to birdshot retinochoroidopathy and to describe the association between therapy and the incidence thereof. DESIGN:Retrospective cohort study. METHODS: SETTING:Single-center, academic practice. STUDY POPULATION:Forty patients w...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.01.035
更新日期:2005-07-01 00:00:00
abstract::A 26-year-old woman experienced bilateral hearing loss, progressive nasal obstruction, and rhinorrhea. Examination disclosed a retropharyngeal mass. A needle biopsy specimen of the mass showed that it was a chordoma. The patient underwent surgery to remove the mass and received a postoperative course of radioactive co...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75899-4
更新日期:1981-07-01 00:00:00
abstract::In the elderly patient with a massive vitreous hemorrhage in one eye and senile macular choroidal degenerative changes in the fellow eye, a hemorrhagic disciform detachment causing this massive vitreous hemorrhage must be considered in the differential diagnosis. Ultrasonography selectively combined with radioactive p...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75023-8
更新日期:1980-10-01 00:00:00
abstract:PURPOSE:To report a case of pityriasis rubra pilaris (PRP)-induced bilateral lower eyelid cicatricial ectropion that resolved with systemic low-dose methotrexate. DESIGN:Observational case report. METHODS:A retrospective case review of a patient with cicatricial ectropion caused by PRP. RESULTS:A 82-year-old female ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.11.038
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To determine whether treatment of macular retinoblastoma with chemotherapy and laser hyperthermia can lead to satisfactory visual acuity. METHODS:A child with unilateral macular retinoblastoma was treated with chemotherapy and laser hyperthermia. Visual function was assessed one year after treatment. RESULTS:...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75441-8
更新日期:1996-05-01 00:00:00
abstract:PURPOSE:To review the progress and challenges in obtaining accurate corneal power measurements for intraocular lens (IOL) calculations. DESIGN:Personal perspective, review of literature, case presentations, and personal data. METHODS:Through literature review findings, case presentations, and data from the author's c...
journal_title:American journal of ophthalmology
pub_type:
doi:10.1016/j.ajo.2016.08.020
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To determine the safety and efficacy of AL-8309B (tandospirone) in the management of patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) and obtain standardized data on GA lesion growth progression. DESIGN:Prospective, controlled, double-masked, randomized, multicenter pha...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2015.08.024
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To investigate whether the statin class of drugs reduces the risk of cataract extraction. DESIGN:Case-control study. METHOD:setting: Kaiser Permanente Southern California, which provides prepaid healthcare for 3.2 million residents by 6000 physicians. patient population: Eligible patients were those who had 5...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.08.001
更新日期:2012-02-01 00:00:00
abstract::A 5-month-old infant girl died of familial lymphohistiocytosis. The central nervous system showed widespread perivascular infiltration of the cerebral pia and arachnoid, the cerebral white matter and deep gray matter, the cerebellum, and brain stem by lymphocytes, benign appearing histiocytes, and macrophages with ery...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90013-1
更新日期:1976-11-01 00:00:00
abstract:PURPOSE:To evaluate the retinal toxicity of intravitreal bevacizumab in an animal model. DESIGN:Animal study. METHODS:Bevacizumab was injected into the vitreous of one eye of each of eight Dutch-belted rabbits; the other eye served as a control. Four rabbits received a dose of 1.25 mg/0.05 ml of bevacizumab intravitr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.03.058
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:Congenital macular lesions attributed to toxoplasmosis may limit potential visual acuity. The appearance and location of these scars may cause physicians to overlook associated amblyopia. This study reviews the visual outcomes and benefits of amblyopia therapy in children with foveal toxoplasmosis scars. DESIG...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.01.034
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:To report a case of progressive necrotizing fasciitis of the face following acute dacryocystitis. DESIGN:Interventional case report. METHODS:A 60-year-old woman presented with left acute dacryocystitis with abscess formation that had ruptured; a small wound remained. Erythematous swelling of the left eyelid a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00089-8
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:To determine the natural history of asymptomatic, clinical rhegmatogenous retinal detachment. DESIGN:Single observer, prospective, consecutive, observational case series. METHODS:Consecutive patients were included who were referred to the author's clinical practice with rhegmatogenous retinal detachment exten...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.01.014
更新日期:2005-05-01 00:00:00
abstract::A 30-year-old man developed bilateral iridocyclitis with iris roseolae and papules three months after the rash of secondary syphilis. The inflammation resolved after treatment with penicillin, intramuscularly, topically given corticosteroids, and cycloplegics. The serum immune-complex levels were slightly increased. I...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74921-9
更新日期:1980-09-01 00:00:00
abstract:PURPOSE:To assess the efficacy and safety of systemic propranolol for infantile capillary hemangiomas of the eyelid. DESIGN:Prospective, interventional cases series. METHODS:All patients with eyelid infantile capillary hemangiomas at risk of developing amblyopia seen between January 2009 and January 2012 at the Unive...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2012.06.021
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:To test the hypothesis that neovascular age-related macular degeneration is related to oxidative stress involving the macular retinal pigment epithelium. This study investigated, as a function of age, levels of enzymes that defend tissues against oxidative stress in the macular retinal pigment epithelium of hum...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00032-x
更新日期:1999-06-01 00:00:00
abstract::Seventeen patients (ten women and seven men, 23 to 72 years old) with stromal herpetic disease were treated with topical and oral acyclovir for 14 days. Of the 12 patients with disciform edema, five showed minimal improvement, four showed no change, and three showed worsening of their disease. Of the five patients wit...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(84)90237-x
更新日期:1984-11-01 00:00:00
abstract:PURPOSE:To investigate the frequency and types of systemic findings in patients with apparently isolated uveal coloboma. DESIGN:Cross-sectional observational study. METHODS:setting: Single-center ophthalmic genetics clinic. study population: Ninety-nine patients with uveal coloboma seen at the National Eye Institute....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.06.037
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:To assess the safety of rAAV.sFlt-1 subretinal injection in neovascular age-related macular degeneration (wet AMD) over 36 months. DESIGN:Phase 1 dose escalation trial. METHODS:Eight subjects with advanced, treatment-experienced wet AMD were randomly assigned (3:1) to treatment and non-gene therapy control gr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajo.2017.02.018
更新日期:2017-05-01 00:00:00
abstract::We reviewed the records of 74 patients with exfoliation syndrome. Patients with exfoliation syndrome represented 12% of the current Glaucoma Clinic population. There were 40 unilateral and 34 bilateral cases. Thirteen percent of the patients who originally had unilateral exfoliation later developed exfoliation in the ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90054-9
更新日期:1980-04-01 00:00:00
abstract::Follow-up examinations, ranging from four to more than 20 years, were performed on 100 patients with chronic cyclitis whose ages at onset were from 4 to 58 years. Cataracts were found in 42% of eyes and macular disease secondary to macular edema in 28% of eyes. Band keratopathy, glaucoma, retinal detachment, retinosch...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90434-7
更新日期:1976-08-01 00:00:00
abstract:PURPOSE:To examine changes in the outer layer of the detached retina in rhegmatogenous retinal detachment (RRD) and central serous chorioretinopathy (CSC) with optical coherence tomography (OCT). DESIGN:Retrospective, observational case series. METHODS:Fifteen eyes (15 patients) with RRD and 16 eyes (16 patients) wit...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.09.030
更新日期:2009-03-01 00:00:00