[Bilateral optic disk edema in polyneuropathy, organomegaly, endocrinopathy, monoclonal proteins and skin changes (POEMS syndrome)].

Abstract:

BACKGROUND:POEMS occurs only in about 1% of plasmocytoma cases, but in more than 50% of the rare osteosclerotic subtypes and plasma cell dyscrasias. The estimated frequency is 20 cases per year in Germany. Swelling of the optic disks is an early sign of the syndrome. CASE REPORT:An osteosclerotic plasmocytoma type IgA lambda was known in a 63-year-old farmer for 4 years. The primary lesion in the left femur was irradiated at diagnosis. Half a year prior to our examination the patient experienced edema of the legs and recurrent diarrhea. A staging confirmed the earlier diagnosis of a POEMS syndrome. The patient was presented for ophthalmologic examination because of optic disk swelling and progressive visual field defects: raster perimetry revealed enlarged blind spots and increased thresholds. Neurologic examination revealed polyradiculitis, increased protein levels in the cerebrospinal fluid and intracranial hypertension. The patient was treated with oral steroids which entailed improvement of the visual fields and decrease of optic disk swelling. CONCLUSIONS:Ophthalmologists play an active role in the staging, in the ruling out of other causes, and in the treatment. Symptomatic treatment with oral steroids should be monitored with visual acuity, raster perimetry and fundus examinations.

journal_name

Klin Monbl Augenheilkd

authors

Barry JC,Gleichmann M,Wilhelm H

doi

10.1055/s-2008-1034671

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

59-63

issue

1

eissn

0023-2165

issn

1439-3999

journal_volume

215

pub_type

杂志文章,评审
  • [Diagonal incision in capsulotomy for extracapsular cataract extraction].

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    authors: Mitschischek E

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  • [Empty sella turcica and papilloedema (author's transl)].

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    doi:

    authors: Szécsi K

    更新日期:1978-04-01 00:00:00

  • [Clinical and fluorescein angiography findings in patients with retinal vein occlusion. A unicenter study of 211 patients].

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    doi:10.1055/s-2008-1045901

    authors: Lang GE,Freissler K

    更新日期:1992-10-01 00:00:00

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    doi:10.1055/s-0031-1299250

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    更新日期:2012-04-01 00:00:00

  • [The American Optical non-contact tonometer and its results compared with the Goldmann applanation tonometer (author's transl)].

    abstract::Intraocular pressure (IOP) of 617 eyes was measured with both an AO non-contact tonometer (NCT) and a Goldmann applanation tonometer (GAT). - Statistical evaluation and the scattergram gave the following results: Correlation coefficient r = 0.74. Regression line y = 3.01 + 0.8x. Close agreement between mean GAT (17.8 ...

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    doi:10.1055/s-2008-1057700

    authors: Derka H

    更新日期:1980-11-01 00:00:00

  • [Clinical and molecular genetic findings in isolated sporadic Duane syndrome].

    abstract:BACKGROUND:Duane retraction syndrome (DURS) accounts for 1 - 4 % of all cases of strabismus. Approximately 90 % of the cases are sporadic with a preponderance for females and the left eye. Many associated ocular and systemic findings have been described. Recently, mutations of SALL4 have been found in patients with aut...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2004-813662

    authors: Wabbels BK,Kohlhase J,Lorenz B

    更新日期:2004-10-01 00:00:00

  • [Initial results in percutaneous radiotherapy of malignant melanomas of the choroid with the linear accelerator].

    abstract::Twenty-seven eyes harboring a choroidal melanoma which could not be treated by other methods were treated with external beam radiation using a linear accelerator. After a mean follow-up period of 15.6 months 3 eyes had to be enucleated. In two eyes fresh tumors developed, which were successfully treated with local bet...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1054595

    authors: Bornfeld N,Alberti W,Foerster MH,Gerke E,Wessing A,Meyer-Schwickerath G

    更新日期:1984-09-01 00:00:00

  • [Zinc concentration in the aqueous humor (author's transl)].

    abstract::The zinc concentration in normal human aqueous humor was determined with the help of an atomic absorption spectrophotometer. The mean value was 0.359 ppm with a scatter range of 0.27 to 0.44 ppm. The spectrophotometer permits simultaneous determination of two metals, in this case zinc and copper. It was possible to de...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057525

    authors: Gerhard JP,Calmé P,Kraeminger E

    更新日期:1980-04-01 00:00:00

  • [Pars plana vitrectomy in proliferative diabetic retinopathy].

    abstract::In this contribution the authors present the results of treatment by pars plana vitrectomy in a consecutive series of 200 patients with proliferative retinopathy. Anatomical success was achieved in 82% of the cases of simple vitreous hemorrhages, in 63% and 67% respectively of the cases of traction detachment with or ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050630

    authors: Krampitz-Glaas G,Laqua H

    更新日期:1986-04-01 00:00:00

  • [II: Difference plots or scattergram--when to use which?].

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    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-35165

    authors: Krummenauer F

    更新日期:2002-09-01 00:00:00

  • [A contribution to the management of paracentral retinal branch vein obstruction (author's transl)].

    abstract::11 eyes (11 patients) with cystoid macular edema secondary to central retinal branch vein occlusion were treated with Laser-coagulations. In 11 eyes macular edema disappeared completely. In 10 eyes visual acuity improved during the next months. One eye developed a macular hole with decrease of visual acuity. The resul...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Paulmann H

    更新日期:1976-04-01 00:00:00

  • [Leukokoria in a child: emergency and challenge].

    abstract:PURPOSE:To heighten the awareness of the medical world to the importance of correct and rapid diagnosis in the presence of leukocoria in the child. METHODS:Starting with the presenting symptom, the authors present the guide lines to follow in a practical manner in order to reach a diagnosis in the principal retinal di...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1034807

    authors: Balmer A,Munier F

    更新日期:1999-05-01 00:00:00

  • [Principals and clinical applications of optical coherence tomography in glaucoma].

    abstract::Optical coherence tomography (OCT) supplies morphological information from different retinal layers. In glaucoma, analysis of the nerve fiber layer is gaining more and more significance: Losses in this layer often precede by years functional losses in the visual field and end up in optical nerve head changes. OCT offe...

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    pub_type: 杂志文章,评审

    doi:10.1055/s-2006-926820

    authors: Parasta AM,Fabian E,Duncker G

    更新日期:2006-08-01 00:00:00

  • [Lamellar keratoplasty, ipsilateral rotation-autokeratoplasty and contralateral autokeratoplasty (author's transl)].

    abstract::During the years 1967--1977, there were performed about 500 mostly perforating keratoplasties. Among these there were special groups: 50 lamellar keratoplasties (43 central, 7 marginal), 5 perforating ipsilateral rotation-autokeratoplasties 2 perforating contralateral autokeratoplasties. The results encourage to use t...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Doden W,Schmitt H,Welt R

    更新日期:1978-10-01 00:00:00

  • [Comparative results of deep sclerectomy transformed to trabeculectomy and classical trabeculectomy].

    abstract:OBJECTIVE:To study the learning risk of a new surgical technique, the deep sclerectomy (DS), which may be complicated with a perforation of the trabeculodescemetic membrane. To do so, we compared the results and the complications of patients who underwent DS transformed in trabeculectomy (DSt) and those of patients who...

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    doi:10.1055/s-2008-1035050

    authors: Sanchez E,Schnyder CC,Mermoud A

    更新日期:1997-05-01 00:00:00

  • [Posterior uveitis in systemic diseases. A pathologic and epidemiologic study].

    abstract::In the course of 2943 autopsies, during which the eyes were also removed, investigations were carried out concerning inflammatory lesions of the posterior uveal tract. Posterior uveitis was found in 202 cases (6.9%) of subjects whose mean age was 74.5 years. In 98% of the cases this was a non-granulomatous inflammatio...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050780

    authors: Hofmann HM,Giarelli L

    更新日期:1986-08-01 00:00:00

  • Inter-Rater Reliability of Cyclotorsion Measurements Using Fundus Photography.

    abstract:BACKGROUND:The foveo-papillary angle (FPA) on fundus photographs is the accepted standard for the measurement of ocular cyclotorsion. We assessed the inter-rater reliability of this method in healthy subjects and in patients with trochlear nerve palsies. PATIENTS AND METHODS:In this methodological study, fundus photog...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0044-101013

    authors: Dysli M,Kanku M,Traber GL

    更新日期:2018-04-01 00:00:00

  • [Bilateral papilledema of unknown etiology in childhood].

    abstract::The author reports on a number of cases of bilateral papilledema of unknown etiology. The condition was presumably caused by a formen virus infection. The symptoms were indicative of increased intracranial pressure; the possibility of a brain tumor therefore had to be ruled out. The results of the neurological examina...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Szabó M

    更新日期:1987-11-01 00:00:00

  • [Choroidal Neovascularisation Other than Typical Neovascular Age-Related Macular Degeneration].

    abstract::Choroidal neovascularisation (CNV) in the context of exsudative age-related macular degeneration (nAMD) can be divided into type 1 (occult) and type 2 (classical) membranes. Retinal angiomatous proliferation (RAP) or polypoidal choroidal vasculopathy (PCV) are "rare subtypes" of chorioretinal neovascularisation and ar...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0042-123833

    authors: Sandner D

    更新日期:2018-08-01 00:00:00

  • [Pattern dystrophies and intrafamilial phenotypic variation].

    abstract:BACKGROUND:Transmitted in an autosomal dominant fashion, the pattern dystrophies involve the retinal pigment epithelium and the external macular retina and are usually divided into four different entities. However, a progression from one form to another is possible, various forms may coexist in the same patient and a c...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035218

    authors: Bernasconi OR,Piguet B

    更新日期:1996-05-01 00:00:00

  • [Value of indocyanine green angiography in localization of occult choroid neovascularization].

    abstract:PURPOSE:To determine the role of Indocyanin Green (ICG) angiography in localizing occult new vessels associated with age-related macular degeneration (ARMD) and assess the possibilities of ICG guided laser photocoagulations. PATIENTS AND METHODS:Fluorescein and ICG angiographies (IMAGEnet system) of 62 patients with o...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035228

    authors: Piguet B,Schalenbourg A,Zografos L

    更新日期:1996-05-01 00:00:00

  • [Experiences with Doppler-ultrasonography of the orbital vessels for ophthalmological vascular diagnosis (author's transl)].

    abstract::With Doppler ultrasonography of the orbit the blood flow in the supratrochlear and supraorbital arteries can be determined transcutaneously. The technique yields reliable informations about the state of the carotid system. It is especially suitable for assessing carotid obstruction. Besides it has proved to be of part...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Bettelheim H,Grabner G

    更新日期:1978-12-01 00:00:00

  • [Efficiency and Therapy Safety of Fractionated Cyclophotocoagulation with up to Ten Laser Spots for Advanced Primary Open-Angle and Pseudoexfoliation Glaucoma].

    abstract:BACKGROUND:Various procedures are available for the treatment of advanced glaucoma. We examined the efficacy and safety of fractionated cyclophotocoagulation (CPC) with up to ten laser spots for advanced primary open-angle glaucoma (POAG) and pseudoexfoliation (PEX) glaucoma treated with maximal topical therapy or eye-...

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    doi:10.1055/a-1057-9699

    authors: Grohmann C,Farrokhi S,Klemm M

    更新日期:2020-02-03 00:00:00

  • [An approach to diabetic retinopathy].

    abstract::Presentation of ophthalmological taking in charge program of the diabetic patients, program elaborated during a symposium in London under the supervision of the World's Health Organisation and the International Federation of Diabetes. A calendar of the necessary controls is worked out. A scheme of the proposed treatme...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1045832

    authors: Ducrey N

    更新日期:1992-05-01 00:00:00

  • [Timolol: long-term results, tolerance test and early-morning measurements (author's transl)].

    abstract::In a study lasting 16 months, Timolol was tested on 57 eyes of a group of selected patients with open-angle glaucoma. Patients whose IOP could not be stabilized with the 0.25% solution were treated with 0.5% drops twice a day. In five separate cases, where regulation was inadequate, pilocarpine 2% twice a day was pres...

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    pub_type: 临床试验,杂志文章

    doi:

    authors: Strempel I

    更新日期:1979-11-01 00:00:00

  • [Surface quality of flexible silicone intraocular lenses. A scanning electron microscopy study].

    abstract:BACKGROUND:Soft intraocular lenses (IOLs) have been developed to be folded during insertion to allow implantation through a small incision. The surface of the IOL is of great importance in postoperative inflammation and long-term acceptance of the implant. Rough and sharp edges can damage delicate intraocular tissues. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035377

    authors: Kohnen T,Magdowski G,Koch DD

    更新日期:1995-10-01 00:00:00

  • [Intravitreal Ranibizumab Injection for the Treatment of Occult and Classic CNV in Exsudative AMD].

    abstract:BACKGROUND:Double-blind, randomised, placebo-controlled and multicentre studies have proven an increase in visual acuity in one-third of the patients receiving Ranibizumab (0.5 mg) injections, who suffer from exsudative AMD. The purpose of this study was to evaluate the early effects of intravitreal Ranibizumab therapy...

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    doi:10.1055/s-0029-1245131

    authors: Maier MM,Feucht N,Fegert C,Fiore B,Winkler von Mohrenfels C,Lohmann C

    更新日期:2011-02-01 00:00:00

  • [Sensitivity of the computer perimeter Competer in early glaucomatous loss of visual field. A controlled study].

    abstract::Comparative examinations were carried out under controlled conditions in 101 eyes of 66 open-angle glaucoma patients with field defects (Stages I-III according to Aulhorn) with the Octopus and Competer computerized perimeters. The results of the Octopus perimetry were selected as a reference system to evaluate the sen...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1055050

    authors: Gramer E,Gerlach R,Krieglstein GK

    更新日期:1982-03-01 00:00:00

  • [Silent sinus syndrome: an unusual cause of vertical diplopia].

    abstract:BACKGROUND:Causes of transient vertical diplopia include myasthenia, dysthyroid orbitopathy, multiple sclerosis, decompensation of a pre-existing state. PURPOSE:To describe an unusual cause of transient diplopia, silent sinus syndrome. METHODS:Clinical, radiological and pathology findings from a 55-year-old man with ...

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    doi:10.1055/s-2008-1034917

    authors: Durig J,Borruat FX,Jaques B

    更新日期:1998-05-01 00:00:00

  • [A convex-concave contact lens for vitreoretinal operations with the BIOM].

    abstract::A new convex-concave contact lens for wide-angle vitreoretinal surgery with the BIOM was developed. Placed on an eye, in which silicone oil is injected, it prevents the formation of an optically disturbing oil-water-film on the surface of the cornea. Thus the new contact lens leads to an essential improvement of the f...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1045932

    authors: Eckardt C,Wiechens B

    更新日期:1991-01-01 00:00:00