Syndrome of inappropriate secretion of antidiuretic hormone in malignancy.

Abstract:

OBJECTIVES:To provide a review of pathophysiology, epidemiology, signs and symptoms, diagnosis, treatment, and nursing management of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in malignancy. DATA SOURCES:Research reports, review articles, and book chapters relevant to SIADH. CONCLUSIONS:The principle cause of hyponatremia in malignancy is SIADH. Early recognition and prompt treatment can prevent serious neurologic sequelae. Antineoplastic therapy and methods to correct hyponatremia constitute effective treatment strategies. IMPLICATIONS FOR NURSING PRACTICE:Nurses play a major role in nursing assessment, appropriate interventions and symptom control, and promoting resolution of problems and optimal quality of life in patients with malignancy complicated by SIADH.

journal_name

Semin Oncol Nurs

authors

Keenan AM

doi

10.1016/s0749-2081(99)80003-5

subject

Has Abstract

pub_date

1999-08-01 00:00:00

pages

160-7

issue

3

eissn

0749-2081

issn

1878-3449

pii

S0749-2081(99)80003-5

journal_volume

15

pub_type

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