Abstract:
:In 16 patients with pulmonary fibrosis, an artificial pneumothorax was introduced using the Veress cannula and the Saugman water manometer. Atmospheric air was introduced by fractionated insufflation to a total volume of 800 ml (median). The interpleural space was found on the first attempt, and in all cases, fractionated insufflation of atmospheric air was conducted while the intrapleural pressure was controlled with the water manometer. In one case, the procedure was stopped because of a rise in the pleural pressure after insufflation of only 50 ml air. This was undoubtedly caused by pleural adhesions not visible on chest X-ray. The main concern with air insufflation is air embolism but this was not observed clinically in any of the present cases. The patients in the present study all suffered from pulmonary fibrosis judged by clinical examination, chest X-ray and pulmonary function tests. Despite a diffusion capacity (DCO/VA) with a median value of 48% expected, the procedure was well tolerated. It has previously been shown that artificial pneumothorax preceding thoracoscopy is well tolerated due to hyperventilation, with an increase in respiratory frequency and a fall in arterial CO2 concentration (PaCO2), while pH and arterial O2 concentration (PO2) remain constant. This probably also explains the tolerance of the patients in this material. Insufflation of air as described here should be restricted to senior pulmonologists because it is an infrequent procedure. The present authors found the procedure to be uncomplicated and easy to perform with little discomfort to the patients.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Faurschou P,Viskum Kdoi
10.1016/s0954-6111(97)90253-5subject
Has Abstractpub_date
1997-08-01 00:00:00pages
402-5issue
7eissn
0954-6111issn
1532-3064pii
S0954-6111(97)90253-5journal_volume
91pub_type
临床试验,杂志文章abstract::Chronic obstructive pulmonary disease (COPD) is increasing in prevalence, and is predicted to become the third leading cause of deaths worldwide by 2020. The precise prevalence of COPD is not known, as many individuals with the disease are left undiagnosed, despite the requirement of only simple spirometry testing for...
journal_title:Respiratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rmed.2009.02.013
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章,随机对照试验
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,meta分析
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2005.11.008
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doi:10.1016/j.rmed.2007.07.011
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pub_type: 杂志文章
doi:10.1016/s0954-6111(06)80060-0
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doi:10.1016/j.rmed.2007.01.002
更新日期:2007-07-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-12-01 00:00:00
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doi:10.1016/s0954-6111(99)90106-3
更新日期:1999-09-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2013-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.rmed.2004.01.014
更新日期:2004-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2008.11.004
更新日期:2009-04-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/s0954-6111(99)90068-9
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pub_type: 杂志文章
doi:10.1016/j.rmed.2017.10.010
更新日期:2017-11-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章,评审
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更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Nitrite in exhaled breath condensate (EBC) has been shown to be elevated in cystic fibrosis (CF), while exhaled nitric oxide (FENO) is paradoxically low. This has been argued to reflect increased metabolism of NO while its diffusion is obstructed by mucus. However, we wanted to study the possible influence o...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2008.09.009
更新日期:2009-02-01 00:00:00