Abstract：
:Ganglioglioma is a tumor composed of neoplastic neurons and neoplastic glial cells mixed in different proportions. Astrocytes are the essential glial component. The tumor proliferates mostly in the temporal lobe cortex, scarcely in other areas of the brain. In ganglioglioma the population of ganglionic neurons is very difficult to diagnose. In the last ten years, immunocytochemical reaction with synaptophysin and neurofilament protein (NFP) triad considered as neoplastic neuron markers seemed to differentiate neoplastic nerve cells from normal neurons occurring incidentally within neoplastic proliferation area. In our study, the reaction with synaptophysin and NFP was performed on fragments of normal frontal lobe, pons and cerebellum as well as on fragments of post-operation tumor diagnosed as ganglioglioma. A positive synaptophysin reaction was obtained on the surface of neoplastic neurons in gangliogliomas, as well as on the surface of normal neurons in the encephalon, cerebellum and pons. Both neoplastic and normal neurons and their processes showed the expression of neurofilaments protein triad. Thus, a positive reaction of neurons with synaptophysin and NFP seems to be nonpathognomic in the diagnosis of the neoplastic neuron population in gangliogliomas.
journal_name
Folia Neuropatholjournal_title
Folia neuropathologicaauthors
Wierzba-Bobrowicz T,Schmidt-Sidor B,Gwiazda E,Bertrand Esubject
Has Abstractpub_date
1999-01-01 00:00:00pages
157-61issue
3eissn
1641-4640issn
1509-572Xjournal_volume
37pub_type
杂志文章abstract：:Angiocentric glioma (AG) is a newly-classified, very rare, WHO grade I central nervous system (CNS) lesion, occurring usually in children and young adults. Only 52 patients with AG have been reported so far, making it one of the rarest neuropathological entities. Hereby we present two new cases of AG in young subjects...
journal_title：Folia neuropathologica
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journal_title：Folia neuropathologica
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journal_title：Folia neuropathologica
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journal_title：Folia neuropathologica
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更新日期：2000-01-01 00:00:00
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journal_title：Folia neuropathologica
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journal_title：Folia neuropathologica
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更新日期：2010-01-01 00:00:00
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journal_title：Folia neuropathologica
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更新日期：2002-01-01 00:00:00
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journal_title：Folia neuropathologica
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journal_title：Folia neuropathologica
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更新日期：2007-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
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journal_title：Folia neuropathologica
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doi：
更新日期：2011-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
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journal_title：Folia neuropathologica
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doi：
更新日期：2000-01-01 00:00:00
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journal_title：Folia neuropathologica
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doi：
更新日期：2001-01-01 00:00:00
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journal_title：Folia neuropathologica
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doi：
更新日期：2006-01-01 00:00:00
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更新日期：1997-01-01 00:00:00
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journal_title：Folia neuropathologica
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doi：
更新日期：1997-01-01 00:00:00
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更新日期：2019-01-01 00:00:00
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journal_title：Folia neuropathologica
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doi：
更新日期：2008-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章,评审
doi：10.5114/fn.2012.32364
更新日期：2012-01-01 00:00:00
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journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Electron microscopic immunocytochemical evaluation of localization and distribution of endothelins 1, 2 and 3 in the CA1 hippocampal sector in rats submitted to 10 min global cerebral ischemia was performed. The studies were done in different postischemic periods (10 min, 3, 6, 12 and 24 h) with postembedding immuno-g...
journal_title：Folia neuropathologica
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
