Diagnosis of ventilator-associated pneumonia: an evaluation of direct examination and presence of intracellular organisms.

abstract：BACKGROUND:Serious complications related to regional anesthesia have previously been described primarily in case reports and retrospective surveys. The authors prospectively evaluated a multicenter series of regional anesthetics, using preplanned criteria to measure the incidence and characteristics of associated serio...

journal_title：Anesthesiology

authors： Auroy Y,Narchi P,Messiah A,Litt L,Rouvier B,Samii K

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Perfluorocarbon liquids are being used experimentally and in clinical trials for the treatment of acute lung injury. Their resemblance to inhaled anesthetic agents suggests the possibility of application by vaporization. The authors' aim was to develop the technical means for perfluorocarbon vaporization and...

journal_title：Anesthesiology

authors： Bleyl JU,Ragaller M,Tschö U,Regner M,Kanzow M,Hübler M,Rasche S,Albrecht M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Clinical concentrations of volatile anesthetics significantly influence contractile response to the sympathetic neurotransmitter norepinephrine although its precise mechanisms remain unclarified. In this study, we investigated its possible alterations in diabetes, as well as its underlying mechanisms. METHO...

journal_title：Anesthesiology

authors： Yoshino J,Akata T,Shirozu K,Izumi K,Hoka S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Hyperkalemic cardiac arrest after the administration of succinylcholine (SCh) to critically ill intensive care patients has been attributed to changes in the acetylcholine receptors (AChRs) at the muscle membrane. The current study attempts to characterize the contributory roles of chronic administration of ...

journal_title：Anesthesiology

authors： Yanez P,Martyn JA

更新日期：1996-02-01 00:00:00

abstract：:The effects of increased intracranial pressure (ICP) and increased cardiac output (QT) on the pulmonary vascular response to regional alveolar hypoxia were compared in pentobarbital-anesthetized, closed-chested dogs. A bronchial divider was inserted, the right lung (RL) was continuously ventilated with 100% O2, and th...

journal_title：Anesthesiology

authors： Domino KB,Hlastala MP,Cheney FW

更新日期：1990-03-01 00:00:00

abstract：:Distribution and elimination of lidocaine and mepivacaine were studies in 114 subjects after obstetric epidural anesthesia, Epinephrine significantly lowered the concentrations of lidocaine in the mothers' circulations by about 33 per cent, and the concentrations of mepivacaine by about 22 per cent. It also significan...

journal_title：Anesthesiology

authors： Brown WU,Bell GC,Lurie AO,Weiss B,Scanlon JW,Alper MH

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:The value of exercise electrocardiography in the prediction of perioperative cardiac risk has yet to be defined. This study was performed to determine the predictive value of exercise electrocardiography as compared with clinical parameters and resting electrocardiography. METHODS:A total of 204 patients at...

journal_title：Anesthesiology

authors： Gauss A,Röhm HJ,Schäuffelen A,Vogel T,Mohl U,Straehle A,Meierhenrich R,Georgieff M,Steinbach G,Schütz W

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The relative contributions of intraoperative and postoperative hypotension to perioperative morbidity remain unclear. We determined the association between hypotension and a composite of 30-day myocardial infarction and death over three periods: (1) intraoperative, (2) remaining day of surgery, and (3) durin...

journal_title：Anesthesiology

authors： Sessler DI,Meyhoff CS,Zimmerman NM,Mao G,Leslie K,Vásquez SM,Balaji P,Alvarez-Garcia J,Cavalcanti AB,Parlow JL,Rahate PV,Seeberger MD,Gossetti B,Walker SA,Premchand RK,Dahl RM,Duceppe E,Rodseth R,Botto F,Devereaux P

更新日期：2018-02-01 00:00:00

abstract：:The effects of anesthetic drugs on lipid order were evaluated by the fluorescence polarization of the probe molecule, 1,6-diphenyl-1,3,5-hexatriene (DPH) incorporated into vesicles of dimyristoylphosphatidylcholine (DMPC) and DMPC with 10 mol% ganglioside (GD1a). Anesthetics (enflurane, chloroform, diethylether, pento...

journal_title：Anesthesiology

authors： Harris RA,Groh GI

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Increasing age appears to be associated with a slower onset of neuromuscular blockade, but such an effect has not been studied with the same doses of the same drugs across pediatric and adult age groups. METHODS:The authors measured the evoked compound action potential of the adductor pollicis muscle in res...

journal_title：Anesthesiology

authors： Koscielniak-Nielsen ZJ,Bevan JC,Popovic V,Baxter MR,Donati F,Bevan DR

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) formed from L-arginine is exhaled by mammals and regulates pulmonary vascular tone. Little is known about how its formation is stimulated. METHODS:The concentration of NO in exhaled air was monitored by chemiluminescence in pentobarbital-anesthetized rabbits receiving mechanical ventilatio...

journal_title：Anesthesiology

authors： Persson MG,Lönnqvist PA,Gustafsson LE

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:The authors' purpose of this study was to elucidate the mechanisms of direct effects of halothane on the contractile proteins and Ca2+ release from the sarcoplasmic reticulum Ca2+ stores using isolated skinned strips (sarcolemma permealized with saponin) from rabbit pulmonary arteries. METHODS:The sarcoplas...

journal_title：Anesthesiology

authors： Su JY,Tang LJ

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Halothane and isoflurane have been reported to suppress the contraction of vascular smooth muscle, although the exact mechanism has not been explained fully. This study examined the effect of halothane and isoflurane on cytosolic calcium ion (Ca2+) concentrations ([Ca2+]cyt), which was measured simultaneousl...

journal_title：Anesthesiology

authors： Tsuchida H,Namba H,Yamakage M,Fujita S,Notsuki E,Namiki A

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Moxonidine, a novel imidazoline-alpha2-adrenergic receptor-selective analgesic, was recently identified as antinociceptive but has yet to be evaluated in neuropathic pain models. alpha2-adrenergic receptor-selective analgesics, and high-efficacy opioids, effectively inhibit neuropathic pain behaviors in rode...

journal_title：Anesthesiology

authors： Fairbanks CA,Nguyen HO,Grocholski BM,Wilcox GL

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Persistent postsurgical pain is common and affects quality of life. The hypothesis was that use of pregabalin and ketamine would prevent persistent pain after cardiac surgery. METHODS:This randomized, double-blind, placebo-controlled trial was undertaken at two cardiac surgery centers in the United Kingdom....

journal_title：Anesthesiology

authors： Anwar S,Cooper J,Rahman J,Sharma C,Langford R

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Propofol is an intravenous anesthetic agent that may impair host defense system. The aim of this study was to evaluate the effects of propofol on macrophage functions and its possible mechanism. METHODS:Mouse macrophage-like Raw 264.7 cells were exposed to propofol, at 3, 30 (a clinically relevant concentra...

journal_title：Anesthesiology

authors： Chen RM,Wu CH,Chang HC,Wu GJ,Lin YL,Sheu JR,Chen TL

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Few data support an association between blood pressure variability and clinical outcomes during cardiac surgery. We tested the hypothesis that intraoperative systolic blood pressure variability outside a targeted blood pressure range predicts 30-day mortality in patients undergoing cardiac surgery. METHODS:...

journal_title：Anesthesiology

authors： Aronson S,Stafford-Smith M,Phillips-Bute B,Shaw A,Gaca J,Newman M,Cardiothoracic Anesthesiology Research Endeavors.

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Investigators in the authors' laboratory previously established the critical participation of the cerulospinal noradrenergic pathway in muscular rigidity elicited by fentanyl. The identification of colocalization of glutamate with tyrosine hydroxylase in most locus ceruleus neurons suggests a role for cerulo...

journal_title：Anesthesiology

authors： Fu MJ,Tsen LY,Lee TY,Lui PW,Chan SH

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Isoflurane has been said to be more ventilatory depressant than halothane. However, data for comparing the respiratory effects of halothane and isoflurane in humans are insufficient at this time. The aim of this study was to extend our understanding of the nature of the central, as opposed to peripheral, ven...

journal_title：Anesthesiology

authors： Canet J,Sanchis J,Zegrí A,Llorente C,Navajas D,Casan P

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Malignant hyperthermia is associated with mutations within the gene encoding the skeletal muscle ryanodine receptor, the calcium channel that releases Ca from sarcoplasmic reticulum stores triggering muscle contraction, and other metabolic activities. More than 200 variants have been identified in the ryanod...

journal_title：Anesthesiology

authors： Sato K,Pollock N,Stowell KM

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Telephone quitlines that provide counseling support are efficacious in helping cigarette smokers quit and have been widely disseminated; currently, they are underused. Surgery represents a teachable moment for smoking cessation, which can benefit surgical outcomes; however, few surgical patients receive smok...

journal_title：Anesthesiology

authors： Warner DO,Klesges RC,Dale LC,Offord KP,Schroeder DR,Shi Y,Vickers KS,Danielson DR

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Neosaxitoxin (NeoSTX) is a site-1 sodium channel blocker that produces prolonged local anesthesia in animals and humans. Under a Food and Drug Administration-approved phase 1 Investigational New Drug trial, the authors evaluated safety and efficacy of NeoSTX alone and combined with 0.2% bupivacaine (Bup) wit...

journal_title：Anesthesiology

authors： Lobo K,Donado C,Cornelissen L,Kim J,Ortiz R,Peake RW,Kellogg M,Alexander ME,Zurakowski D,Kurgansky KE,Peyton J,Bilge A,Boretsky K,McCann ME,Berde CB,Cravero J

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Cardiac surgery requiring cardiopulmonary bypass is associated with platelet activation. Because platelets are increasingly recognized as important effectors of ischemia and end-organ inflammatory injury, the authors explored whether postoperative nadir platelet counts are associated with acute kidney injury...

journal_title：Anesthesiology

authors： Kertai MD,Zhou S,Karhausen JA,Cooter M,Jooste E,Li YJ,White WD,Aronson S,Podgoreanu MV,Gaca J,Welsby IJ,Levy JH,Stafford-Smith M,Mathew JP,Fontes ML

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Rocuronium, like other steroidal nondepolarizing muscle relaxants, may in part be eliminated by the liver. To determine the influence of liver disease on its neuromuscular blocking effect, we studied the pharmacokinetics and pharmacodynamics of rocuronium in patients with cirrhosis. METHODS:Eighteen patient...

journal_title：Anesthesiology

authors： Khalil M,D'Honneur G,Duvaldestin P,Slavov V,De Hys C,Gomeni R

更新日期：1994-06-01 00:00:00

abstract：:The authors present a simple and clinically applicable method for the serial monitoring of pulmonary microvascular enzyme function in vivo. This method requires the intravenous injection of trace amounts of a radiolabelled substrate and the collection of a single arterial blood sample. Simultaneous measurement of pulm...

journal_title：Anesthesiology

authors： Toivonen HJ,Makari N,Catravas JD

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Inhaled nitric oxide (NO), a selective vasodilator, improves oxygenation in many patients with adult respiratory distress syndrome (ARDS). Vasoconstrictors may also improve oxygenation, possibly by enhancing hypoxic pulmonary vasoconstriction. This study compared the effects of phenylephrine, NO, and their c...

journal_title：Anesthesiology

authors： Doering EB,Hanson CW 3rd,Reily DJ,Marshall C,Marshall BE

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Although previous studies have proposed that anesthetics may influence signal transduction systems, their effects on the beta-adrenoceptor-mediated system have not been fully characterized in vascular smooth muscle. The aim of this study was to determine how halothane and isoflurane affect beta-adrenoceptor-...

journal_title：Anesthesiology

authors： Tanaka S,Tsuchida H

更新日期：1998-11-01 00:00:00

abstract：:Critically ill patients must often breathe spontaneously through an endotracheal tube that acts as a fixed inspiratory and expiratory tubular airway resistor. Although this practice is common, its effect on the pattern of breathing is not known. The mean breathing patterns of seven normal, healthy male subjects and ei...

journal_title：Anesthesiology

authors： Weissman C,Askanazi J,Rosenbaum SH,Damask MC,Hyman AI,Kinney JM

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Recent evidence indicates that vascular adenosine triphosphate-sensitive potassium (K(ATP)) channels in vascular smooth muscle cells are critical in the regulation of vascular tonus under both physiologic and pathophysiologic conditions. Studies of the interaction of volatile anesthetics with vascular K(ATP)...

journal_title：Anesthesiology

authors： Tanaka K,Kawano T,Nakamura A,Nazari H,Kawahito S,Oshita S,Takahashi A,Nakaya Y

更新日期：2007-05-01 00:00:00

abstract：:Changes in hepatic plasma flow (HPF) during sodium nitroprusside (SNP) induced hypotension were studied in 14 patients undergoing intracranial aneurysm surgery under neurolept anesthesia. Patients were monitored with the use of a radial artery catheter and a thermistor-tipped Swan-Ganz catheter. Hypotension was induce...

journal_title：Anesthesiology

authors： Chauvin M,Bonnet F,Montembault C,Lafay M,Curet P,Viars P

更新日期：1985-09-01 00:00:00