High prevalence of hantavirus infection in a group of Chinese patients with acute hepatitis of unknown aetiology.

abstract：:Injecting behaviour in people who inject drugs is the main risk factor for hepatitis C virus (HCV) infection. Psychosocial factors such as having a partner who injects drugs and living with other drug users have been associated with increases in injecting risk behaviour. This study aimed to investigate changes in inje...

journal_title：Journal of viral hepatitis

authors： Malaguti A,Sani F,Stephens BP,Ahmad F,Dugard P,Dillon JF,ERADICATE-C Study Group.

更新日期：2019-01-01 00:00:00

abstract：:Only in a minority of patients with chronic hepatitis B (CHB) will treatment with interferon (IFN)-alpha or nucleoside analogues lead to sustained virological response. In vivo immunization (IVI) following virus suppression aims to optimize conditions for an effective immune response: following rapid and profound viru...

journal_title：Journal of viral hepatitis

authors： Sprengers D,van der Molen RG,Binda R,Kusters JG,de Man RA,Niesters HG,Schalm SW,Janssen HL

更新日期：2007-10-01 00:00:00

abstract：:Several direct-acting antivirals (DAAs) have been approved for the treatment of chronic hepatitis C virus (HCV) infections, opening the door to highly effective interferon-free treatment regimens. Resistance-associated substitutions (RASs) have been reported both in treatment-naïve patients and following treatment wit...

journal_title：Journal of viral hepatitis

authors： Eltahla AA,Rodrigo C,Betz-Stablein B,Grebely J,Applegate T,Luciani F,Schinkel J,Dore GJ,Page K,Bruneau J,Morris MD,Cox AL,Kim AY,Shoukry NH,Lauer GM,Maher L,Hellard M,Prins M,Lloyd AR,Bull RA,InC3 Study Group.

更新日期：2017-01-01 00:00:00

abstract：:Although the incidence of new hepatitis C virus (HCV) infection has fallen, HCV-related complications are on the rise. Our aim was to assess and describe the 2005-2009 national inpatient mortality and resource utilization trends for patients with HCV. Data from the National Inpatient Sample (NIS) and the National Hosp...

journal_title：Journal of viral hepatitis

authors： Younossi ZM,Otgonsuren M,Henry L,Arsalla Z,Stepnaova M,Mishra A,Venkatesan C,Hunt S

更新日期：2015-02-01 00:00:00

abstract：:Viral load reduction facilitates recovery of antiviral T-cell responses. Dynamic alterations in intrahepatic viraemia clearance and immune cell reactivity during the early phase of nucleoside analogue (NA) therapy and the impact of these changes on HBeAg seroconversion are unknown. Fifteen HBeAg-positive chronic hepat...

journal_title：Journal of viral hepatitis

authors： Zheng Q,Zhu YY,Chen J,Liu YR,You J,Dong J,Zeng DW,Gao LY,Chen LH,Jiang JJ

更新日期：2014-12-01 00:00:00

abstract：:The short-term prognosis of patients with severe acute exacerbation of chronic hepatitis B (CHB) leading to acute liver failure is extremely poor. We have reported the efficacy of corticosteroid in combination with nucleoside analogue in the early stages, but virological efficacy has not been documented. Our aim was t...

journal_title：Journal of viral hepatitis

authors： Yasui S,Fujiwara K,Nakamura M,Miyamura T,Yonemitsu Y,Mikata R,Arai M,Kanda T,Imazeki F,Oda S,Yokosuka O

更新日期：2015-02-01 00:00:00

abstract：:The aims of the present study were to evaluate the efficacy and tolerability of ledipasvir/sofosbuvir (LDV/SOF) with or without ribavirin in the treatment of chronic hepatitis C (CHC) in patients with advanced liver disease and to analyse whether the use of LDV/SOF treatment is associated with a new occurrence of hepa...

journal_title：Journal of viral hepatitis

authors： Idilman R,Demir M,Aladag M,Erol C,Cavus B,Iliaz R,Koklu H,Cakaloglu Y,Sahin M,Ersoz G,Koksal İ,Karasu Z,Ozgenel M,Turan İ,Gunduz F,Ataseven H,Akdogan M,Kiyici M,Koksal AS,Akhan S,Gunsar F,Tabak F,Kaymakoglu S

更新日期：2019-06-01 00:00:00

abstract：:Approximately 30% of patients with chronic HCV infection have persistently normal ALT levels. Although formerly referred to as 'healthy' or 'asymptomatic' HCV carriers, and thus historically excluded from antiviral treatment, it has now become clear that the majority of these patients have some degree of histological ...

journal_title：Journal of viral hepatitis

authors： Puoti C,Guarisco R,Spilabotti L,Bellis L,Mitidieri Costanza O,Dell' Unto O,Elmo MG

更新日期：2012-04-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection is associated with many extrahepatic malignancies, but its association with and impact on ovarian cancer has not been examined. We therefore examined the prevalence of HBV infection among women with primary ovarian carcinoma in an endemic area, and whether this impacts the presentatio...

journal_title：Journal of viral hepatitis

authors： Wong L,Cheung TH,Yim SF,Lao TT

更新日期：2020-05-01 00:00:00

abstract：:The aim of this study was to evaluate the pharmacokinetic profile of daclatasvir (DCV) and asunaprevir (ASV) dual therapy in haemodialysis patients infected with hepatitis C virus (HCV). Eighteen haemodialysis patients and 54 patients with normal renal function were treated with DCV and ASV dual therapy for 24 weeks. ...

journal_title：Journal of viral hepatitis

authors： Kawakami Y,Imamura M,Ikeda H,Suzuki M,Arataki K,Moriishi M,Mori N,Kokoroishi K,Katamura Y,Ezaki T,Ueno T,Ide K,Masaki T,Ohdan H,Chayama K

更新日期：2016-11-01 00:00:00

abstract：:CH-C negatively affects work productivity (WP), creating a large economic burden. The aim of this study was to model the impact of sustained virologic response (SVR) on WP in CHC genotype 1 (GT1) patients in five European countries (EU5). Work Productivity and Activity Index-Specific Health Problem questionnaire was a...

journal_title：Journal of viral hepatitis

authors： Younossi Z,Brown A,Buti M,Fagiuoli S,Mauss S,Rosenberg W,Serfaty L,Srivastava A,Smith N,Stepanova M,Beckerman R

更新日期：2016-03-01 00:00:00

abstract：:Triple therapy with telaprevir, pegylated interferon and ribavirin has been reported to improve antiviral efficacy but have potentially severe adverse effects in patients with chronic hepatitis C. To avoid the severe effects of telaprevir, lowering the dose has been suggested. However, impact of dosage changes on anti...

journal_title：Journal of viral hepatitis

authors： Oze T,Hiramatsu N,Yakushijin T,Yamada R,Harada N,Morishita N,Oshita M,Mita E,Ito T,Inui Y,Inada M,Tamura S,Yoshihara H,Imai Y,Kato M,Miyagi T,Yoshida Y,Tatsumi T,Kasahara A,Hayashi N,Takehara T

更新日期：2015-03-01 00:00:00

abstract：:Clinical and experimental studies have demonstrated that connective-tissue growth factor (CTGF) expression is increased in fibrotic human liver and experimental animal models of liver fibrogenesis. CTGF has been linked to transforming growth factor-beta (TGF-beta) pathways in fibroproliferative diseases and specific p...

journal_title：Journal of viral hepatitis

authors： Kovalenko E,Tacke F,Gressner OA,Zimmermann HW,Lahme B,Janetzko A,Wiederholt T,Berg T,Müller T,Trautwein C,Gressner AM,Weiskirchen R

更新日期：2009-09-01 00:00:00

abstract：:Many Indigenous Australians in northern Australia living with chronic hepatitis B are unaware of their diagnosis due to low screening rates. A venous blood point of care test (POCT) or oral fluid laboratory test could improve testing uptake in this region. The purpose of this study was to assess the field performance ...

journal_title：Journal of viral hepatitis

authors： Sullivan RP,Davies J,Binks P,Dhurrkay RG,Gurruwiwi GG,Bukulatjpi SM,McKinnon M,Hosking K,Littlejohn M,Jackson K,Locarnini S,Davis JS,Tong SYC

更新日期：2020-04-01 00:00:00

abstract：:Flares in chronic hepatitis B are often detrimental but sometimes lead to sustained immune control and disease remission. The aim of this study was to estimate the frequency of hepatitis flares which occur during and/or after cessation of nucleos(t)ide analogue (NA) therapy, and to assess their outcomes. In a single c...

journal_title：Journal of viral hepatitis

authors： Zhang NP,Reijnders JG,Perquin M,Hansen BE,Janssen HL

更新日期：2011-07-01 00:00:00

abstract：:Significant advances have been made, during the last 5 years, in the treatment of chronic hepatitis B. Several new antiviral agents: lamivudine, famciclovir, lobucavir and adefovir, have been shown to be safe and effective in inhibiting hepatitis B virus (HBV) replication. These compounds can be administered orally an...

journal_title：Journal of viral hepatitis

authors： Hussain M,Lok AS

更新日期：1999-05-01 00:00:00

abstract：:Treatment of chronic hepatitis B has been greatly improved by the use of lamivudine, but mutations occur in the polymerase region of hepatitis B virus (HBV) and lamivudine-resistant mutants frequently develop. The emergence of lamivudine-resistant strains of HBV is a problem for treating chronic hepatitis B using lami...

journal_title：Journal of viral hepatitis

authors： Natsuizaka M,Hige S,Ono Y,Ogawa K,Nakanishi M,Chuma M,Yoshida S,Asaka M

更新日期：2005-03-01 00:00:00

abstract：:It is unknown whether dynamic changes of liver stiffness measurement (LSM) can predict the reversibility of fibrosis. Therefore, we evaluated the utility of LSM changes in predicting histological changes of fibrosis in patients with chronic hepatitis B (CHB) on antiviral therapy. In a prospective cohort of CHB patient...

journal_title：Journal of viral hepatitis

authors： Kong Y,Sun Y,Zhou J,Wu X,Chen Y,Piao H,Lu L,Ding H,Nan Y,Jiang W,Xu Y,Xie W,Li H,Feng B,Shi G,Chen G,Li H,Zheng H,Cheng J,Wang T,Liu H,Lv F,Shao C,Mao Y,Sun J,Chen T,Han T,Han Y,Wang L,Ou X,Zha

更新日期：2019-05-01 00:00:00

abstract：:Hepatitis E virus (HEV) is a major cause of acute hepatitis in many developing countries. Based on data from nonendemic regions, an animal reservoir of HEV has been proposed; however, data from HEV-endemic regions are limited. We tested sera from 200 pigs, 98 chickens, 86 goats, 58 sheep and 30 buffaloes for anti-HEV ...

journal_title：Journal of viral hepatitis

authors： Shukla P,Chauhan UK,Naik S,Anderson D,Aggarwal R

更新日期：2007-05-01 00:00:00

abstract：:With the advent of direct-acting antivirals (DAAs), the treatment of chronic hepatitis C virus (HCV) infection (CHC) has been revolutionized. Modern interferon- and potentially also ribavirin-free combinations consisting of 2 or 3 direct-acting antivirals (DAA) promise sustained virological response rates (SVR) of abo...

journal_title：Journal of viral hepatitis

authors： Boesecke C,Rockstroh JK

更新日期：2015-01-01 00:00:00

abstract：:Both hepatitis B and hepatitis C viruses (HBV and HCV) cause chronic infections worldwide that are associated with development of liver diseases ranging from mild liver inflammation to hepatocellular carcinomas. While efficient preventive vaccines are available for HBV, efforts are ongoing to develop one in case of HC...

journal_title：Journal of viral hepatitis

authors： Inchauspé G,Michel ML

更新日期：2007-11-01 00:00:00

abstract：:The risk of perinatal transmission of hepatitis C virus (HCV) from a cohort of 95 human immunodeficiency virus (HIV)-negative intravenous drug users (IVDU) is described, 89 of whom were positive for antibodies to HCV (anti-HCV). Infection, defined as the presence of HCV RNA in a serum sample collected from an infant a...

journal_title：Journal of viral hepatitis

authors： Spencer JD,Latt N,Beeby PJ,Collins E,Saunders JB,McCaughan GW,Cossart YE

更新日期：1997-01-01 00:00:00

abstract：:Although there are no dietary restrictions recommended in acute viral hepatitis (AVH), there is an altered food intake, probably because of perceptions and traditional nutritional practices, leading to sub-optimal intake and poorer clinical outcome. Therefore, we aimed to determine nutritional intake of AVH patients b...

journal_title：Journal of viral hepatitis

authors： Sathiaraj E,Chutke M,Mahurkar S,Nagaraja Rao P,Nageshwar Reddy D

更新日期：2010-05-01 00:00:00

abstract：:Although tattooing is recognized as a risk factor for transmission of hepatitis C, the efficiency with which transmission occurs is unknown. Sera stored from a serosurvey of tattooists undertaken in 1984 to test for human immunodeficiency virus (HIV) provided the opportunity to determine the prevalence of serological ...

journal_title：Journal of viral hepatitis

authors： Thompson SC,Goudey RE,Breschkin AM,Carnie J,Catton M

更新日期：1997-03-01 00:00:00

abstract：:Chronic hepatitis C virus (HCV) infection eventually leads to cirrhosis in 20-30% of patients and to hepatocellular carcinoma (HCC) in 1-5% of patients. Rates of sustained virological response with standard interferon-alpha (IFN-alpha) are low in patients without cirrhosis (generally < 20%) and are even lower in those...

journal_title：Journal of viral hepatitis

authors： Zeuzem S

更新日期：2000-09-01 00:00:00

abstract：:Chronic infection with the hepatitis C virus is a major health problem. Conventional therapy, with interferon-alpha is effective in only a minority of patients. The failure of current treatments has led to a major initiative to identify new antiviral agents. In the absence of a tissue culture model for hepatitis C inf...

journal_title：Journal of viral hepatitis

authors： Clarke BE

更新日期：1995-01-01 00:00:00

abstract：:For the past decade, a specific hepatitis B virus (HBV) genotype A strain has been prevalent among men having sex with men (MSM) in Amsterdam, the Netherlands. At what point in time this strain was introduced in the MSM population, and why only this specific strain continues to be transmitted, remains unclear. Between...

journal_title：Journal of viral hepatitis

authors： van Houdt R,Bruisten SM,Geskus RB,Bakker M,Wolthers KC,Prins M,Coutinho RA

更新日期：2010-02-01 00:00:00

abstract：:The role of hepatitis C virus (HCV) heterogeneity in the severity of chronic hepatitis C infection remains unclear. Our aim was to study the hypervariable region 1 (HVR1) heterogeneity in patients with chronic hepatitis C infected with genotype 1b or 3 and with normal or abnormal alanine aminotransferase (ALT). HVR1 q...

journal_title：Journal of viral hepatitis

authors： Asselah T,Martinot M,Cazals-Hatem D,Boyer N,Auperin A,Le Breton V,Erlinger S,Degott C,Valla D,Marcellin P

更新日期：2002-01-01 00:00:00

abstract：:The aim of the study was to analyse the current literature regarding the mode of transmission of HCV and its global prevalence in different groups of people. A systematic review of the literature on the epidemiology of hepatitis C from 1991 to 2000 using computerized bibliographic databases which include Medline, Curr...

journal_title：Journal of viral hepatitis

authors： Memon MI,Memon MA

更新日期：2002-03-01 00:00:00

abstract：:Intercellular adhesion molecule-1 (ICAM-1) plays an important role in the pathogenesis of viral hepatitis B. Several inflammatory diseases are associated with distinct polymorphisms of the ICAM-1 gene. The aims of this study were to analyse the association of ICAM-1 polymorphisms G241R and K469E with susceptibility to...

journal_title：Journal of viral hepatitis

authors： Zhang XQ,Hong XJ,Bai XJ

更新日期：2008-03-01 00:00:00