Monte Carlo modelling of electron beams from medical accelerators.

abstract：:For low-energy (up to 150 kV) x-rays, the ratio of mass-energy absorption coefficients for water to air, (mu(en)/rho)w.air, and the backscatter factor B are used in the conversion of air kerma, measured free-in-air, to water kerma on the surface of a water phantom. For clinical radiotherapy, similar conversion factors...

journal_title：Physics in medicine and biology

authors： Ma CM,Seuntjens JP

更新日期：1999-01-01 00:00:00

abstract：:Accurate scatter correction is especially important for high-resolution 3D positron emission tomographies (PETs) such as high-resolution research tomograph (HRRT) due to large scatter fraction in the data. To address this problem, a fully 3D iterative scatter-corrected ordered subset expectation maximization (OSEM) in...

journal_title：Physics in medicine and biology

authors： Kim KS,Ye JC

更新日期：2011-08-07 00:00:00

abstract：:We tested the ability of a single Compton camera (CC) to produce 3-dimensional (3D) images of prompt gammas (PGs) emitted during the irradiation of a tissue-equivalent plastic phantom with proton pencil beams for clinical doses delivered at clinical dose rates. PG measurements were made with a small prototype CC place...

journal_title：Physics in medicine and biology

authors： Draeger E,Mackin D,Peterson S,Chen H,Avery S,Beddar S,Polf JC

更新日期：2018-01-30 00:00:00

abstract：:This paper presents finite-difference time-domain (FDTD) calculations of the whole-body averaged SAR in an anatomically realistic voxel model of the human body. This model, NORMAN, consists of approximately 9 million voxels, of 2 mm dimension in the adult phantom, segmented into 37 tissue types. SAR values are present...

journal_title：Physics in medicine and biology

authors： Dimbylow PJ

更新日期：1997-03-01 00:00:00

abstract：:For medical applications of ultrasound inside the brain, it is necessary to understand the relationship between the apparent density of skull bone and its corresponding speed of sound and attenuation coefficient. Although there have been previous studies exploring this phenomenon, there is still a need to extend the m...

journal_title：Physics in medicine and biology

authors： Pichardo S,Sin VW,Hynynen K

更新日期：2011-01-07 00:00:00

abstract：:Preclinical positron emission tomography, combined with magnetic resonance imaging (PET/MRI), is increasingly used as a tool to simultaneously characterize functional processes in vivo. Many emerging preclinical applications, however, are limited by PET detection sensitivity, especially when generating short imaging f...

journal_title：Physics in medicine and biology

authors： Selfridge AR,Cherry SR,Judenhofer MS

更新日期：2018-12-06 00:00:00

abstract：:Radiation dose distributions have been calculated for 188Re and 32P activity on a coronary artery stent. The doses have been calculated both as a function of position along the stent and of depth into the artery wall. Comparisons of the dose from identical activities of 188Re and 32P on the stent show that the major d...

journal_title：Physics in medicine and biology

authors： Fox RA,Henson PW

更新日期：2000-12-01 00:00:00

abstract：:A solid dynamic phantom with tissue-like optical properties is presented, which contains seven discrete targets impregnated with thermochromic pigment located at different depths from the surface. Changes in absorption are obtained in response to localized heating of the targets, simulating haemodynamic changes occurr...

journal_title：Physics in medicine and biology

authors： Correia T,Banga A,Everdell NL,Gibson AP,Hebden JC

更新日期：2009-10-21 00:00:00

abstract：:An X-ray technique has been developed to enable reproducible and quantitative data to be obtained from radiographs taken by a diagnostic X-ray machine. Careful attention has been paid to the alignment of the specimen and the diagnostic tube and to operating conditions. The choice of X-ray spectrum is described togethe...

journal_title：Physics in medicine and biology

authors： King SD

更新日期：1977-07-01 00:00:00

abstract：:We implemented a hybrid scatter-correction method for 3D PET that combines two scatter-correction methods in a complementary way. The implemented scheme uses a method based on the discrimination of the energy of events (the estimation of trues method (ETM)) and an auxiliary method (the single scatter simulation method...

journal_title：Physics in medicine and biology

authors： Ferreira NC,Trébossen R,Lartizien C,Brulon V,Merceron P,Bendriem B

更新日期：2002-05-07 00:00:00

abstract：:Tumour histological grade has prognostic implications in breast cancer. Tumour features in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and T2-weighted (T2W) imaging can provide related and complementary information in the analysis of breast lesions to improve MRI-based histological status prediction...

journal_title：Physics in medicine and biology

authors： Fan M,Liu Z,Xie S,Xu M,Wang S,Gao X,Li L

更新日期：2019-10-23 00:00:00

abstract：:EEG interictal epileptiform discharges in temporal lobe epilepsy are associated with magnetic fields. The maxima of magnetic spikes recorded over the spherical portions of the head appear fairly symmetric, whereas those over the lower temporal region often have irregular shapes. Furthermore, their magnitude is often u...

journal_title：Physics in medicine and biology

authors： Rose DF,Sato S,Smith PD,White J

更新日期：1987-01-01 00:00:00

abstract：:In a previous paper the calibration of an isotropic light detector in clear media was described and validated. However, in most applications the detector is used to measure light distribution in turbid (scattering) media, that is, in tissues or tissue equivalent optical phantoms. Despite its small diameter (typically ...

journal_title：Physics in medicine and biology

authors： Marijnissen JP,Star WM

更新日期：2002-06-21 00:00:00

abstract：:Enabling automated pipelines, image analysis and big data methodology in cancer clinics requires thorough understanding of the data. Automated quality assurance steps could improve the efficiency and robustness of these methods by verifying possible data biases. In particular, in head and neck (H&N) computed-tomograph...

journal_title：Physics in medicine and biology

authors： Welch ML,McIntosh C,Purdie TG,Wee L,Traverso A,Dekker A,Haibe-Kains B,Jaffray DA

更新日期：2020-01-10 00:00:00

abstract：:In external beam radiation therapy, radioactive beams offer the best clinical solution to simultaneously treat and in vivo monitor the dose delivery and tumor response using PET or PET-CT imaging. However, difficulties mainly linked to the low production efficiency have so far limited their use. This study is devoted ...

journal_title：Physics in medicine and biology

authors： Lazzeroni M,Brahme A

更新日期：2011-03-21 00:00:00

abstract：:Magnetic resonance and ultrasound elastography techniques are now important tools for staging high-grade fibrosis in patients with chronic liver disease. However, uncertainty remains about the effects of simple accumulation of fat (steatosis) and inflammation (steatohepatitis) on the parameters that can be measured us...

journal_title：Physics in medicine and biology

authors： Parker KJ,Ormachea J,Drage MG,Kim H,Hah Z

更新日期：2018-05-17 00:00:00

abstract：:The aim of this study was to evaluate angiogenic compositions and tumour response in the course of neoadjuvant chemotherapy in patients with locally advanced breast cancer (LABC) using dynamic contrast-enhanced (DCE) MRI. Thirteen patients with LABC underwent serial DCE MRI during the course of chemotherapy. DCE MRI w...

journal_title：Physics in medicine and biology

authors： Chang YC,Huang CS,Liu YJ,Chen JH,Lu YS,Tseng WY

更新日期：2004-08-21 00:00:00

abstract：:The dosimetric impact of intrafraction prostate motion was investigated for helical tomotherapy treatments. Measured motion tracks were used to calculate the dosimetric impact on delivered target dose distributions. A dynamic dose calculation engine was developed to facilitate this evaluation. It was found that the D9...

journal_title：Physics in medicine and biology

authors： Langen KM,Lu W,Ngwa W,Willoughby TR,Chauhan B,Meeks SL,Kupelian PA,Olivera G

更新日期：2008-12-21 00:00:00

abstract：:The in vivo electric conductivity (σ) values of tissue are essential for accurate electromagnetic simulations and specific absorption rate (SAR) assessment for applications such as thermal dose computations in hyperthermia. Currently used σ-values are mostly based on ex vivo measurements. In this study the conductivit...

journal_title：Physics in medicine and biology

authors： Balidemaj E,de Boer P,van Lier AL,Remis RF,Stalpers LJ,Westerveld GH,Nederveen AJ,van den Berg CA,Crezee J

更新日期：2016-02-21 00:00:00

abstract：:Scanned ion pencil beams carry a low-dose envelope which can extend up to several centimeters from the individual beam central axis. Depending on the energy and species of the beam, this halo consists mainly of secondary particles produced by nuclear interactions in the target or of particles undergoing multiple Coulo...

journal_title：Physics in medicine and biology

authors： Schwaab J,Brons S,Fieres J,Parodi K

更新日期：2011-12-21 00:00:00

abstract：:Four dimensional cone beam computed tomography (4DCBCT) uses a constant gantry speed and imaging frequency that are independent of the patient's breathing rate. Using a technique called respiratory motion guided 4DCBCT (RMG-4DCBCT), we have previously demonstrated that by varying the gantry speed and imaging frequency...

journal_title：Physics in medicine and biology

authors： O'Brien RT,Stankovic U,Sonke JJ,Keall PJ

更新日期：2017-06-07 00:00:00

abstract：:Effects of different scatter compensation methods incorporated in fully 3D iterative reconstruction are investigated. The methods are: (i) the inclusion of an 'ideal scatter estimate' (ISE); (ii) like (i) but with a noiseless scatter estimate (ISE-NF); (iii) incorporation of scatter in the point spread function during...

journal_title：Physics in medicine and biology

authors： Beekman FJ,Kamphuis C,Frey EC

更新日期：1997-08-01 00:00:00

abstract：:Cylindrical ionization chambers with varying radii have been used to determine the displacement effect at distances between 10 mm and 40 mm from 60Co and 192Ir brachytherapy sources. Agreement with published values of the displacement factor for external 60Co beams is obtained. The shift between the centre of the ioni...

journal_title：Physics in medicine and biology

authors： Tölli H,Johansson KA

更新日期：1993-10-01 00:00:00

abstract：:In BANG gel dosimetry, the spin-spin relaxation rate, R2 = I/T2, is related to the radiation dose that has been delivered to the gel phantom. R2 is calculated by fitting the pixel intensities of a set of differently T2-weighted base images. In gel dosimetry for radiotherapy, an accuracy of 5% in dose and 3 mm spatiall...

journal_title：Physics in medicine and biology

authors： De Deene Y,De Wagter C,De Neve W,Achten E

更新日期：2000-07-01 00:00:00

abstract：:Several papers have recently addressed the issue of estimating chromophore concentration in optoacoustic imaging (OAI) using multiple wavelengths. The choice of wavelengths obviously affects the accuracy and precision of the estimates. One might assume that the wavelengths that maximize the extinction coefficients of ...

journal_title：Physics in medicine and biology

authors： Modgil D,La Riviére PJ

更新日期：2010-12-07 00:00:00

abstract：:We discuss the use of terahertz time domain spectroscopy for studies of conformational flexibility and conformational change in biomolecules. Protein structural dynamics are vital to biological function with protein flexibility affecting enzymatic reaction rates and sensory transduction cycling times. Conformational m...

journal_title：Physics in medicine and biology

authors： Markelz A,Whitmire S,Hillebrecht J,Birge R

更新日期：2002-11-07 00:00:00

abstract：:Determining plaque vulnerability is critical when selecting the most suitable treatment for patients with atherosclerotic plaque. Currently, clinical non-invasive ultrasound-based methods for plaque characterization are limited to visual assessment of plaque morphology and new quantitative methods are needed. In this ...

journal_title：Physics in medicine and biology

authors： Widman E,Maksuti E,Larsson D,Urban MW,Bjällmark A,Larsson M

更新日期：2015-04-21 00:00:00

abstract：:This paper presents a new algorithm for constrained intensity-modulated radiotherapy (IMRT) planning, made tractable by a dimensionality reduction using a set of plans obtained by fast, unconstrained optimizations. The main result is to reduce planning time by an order of magnitude, producing viable five field prostat...

journal_title：Physics in medicine and biology

authors： Lu R,Radke RJ,Yang J,Happersett L,Yorke E,Jackson A

更新日期：2008-12-07 00:00:00

abstract：:This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical obs...

journal_title：Physics in medicine and biology

authors： Lee TS,Frey EC,Tsui BM

更新日期：2015-04-07 00:00:00

abstract：:This work aims to investigate the dosimetric impact of dental implants on volumetric modulated arc therapy (VMAT) for head-and-neck patients and to evaluate the effectiveness of using the material's electron-density ratio for the correction. An in-house Monte Carlo (MC) code was utilized for the dose calculation to ac...

journal_title：Physics in medicine and biology

authors： Lin MH,Li J,Price RA Jr,Wang L,Lee CC,Ma CM

更新日期：2013-02-21 00:00:00