Abstract:
:Ingestion of potentially poisonous agents is a common reason for children to present to an emergency department. The clinician must decide whether gastrointestinal decontamination is indicated for these patients. The controversy over the type of gastrointestinal decontamination is resolving and recent recommendations are reviewed. Also two new antidotes, fomepizole for toxic alcohols and octreotide for sulfonylureas, are reviewed.
journal_name
Pediatr Clin North Amjournal_title
Pediatric clinics of North Americaauthors
Tenenbein Mdoi
10.1016/s0031-3955(05)70181-4subject
Has Abstractpub_date
1999-12-01 00:00:00pages
1179-88, viiissue
6eissn
0031-3955issn
1557-8240pii
S0031-3955(05)70181-4journal_volume
46pub_type
杂志文章,评审abstract::Infant mortality and morbidity disparities occur between non-Indigenous and Indigenous populations of Australia, Canada, New Zealand, and the United States. Neonatal mortality is due to high-risk births, which vary according to prevalence of the maternal risk factors of smoking, alcohol consumption, infection, and dis...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2009.09.009
更新日期:2009-12-01 00:00:00
abstract::Sudden cardiac death (SCD) in children is the result of multiple etiologies and treatment (prophylaxis) must be tailored accordingly. In children who do not have congenital heart disease, surgical therapy of SCD typically consists of implantation of an internal defibrillator, with specific attention to the small size ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2004.04.003
更新日期:2004-10-01 00:00:00
abstract::This article focuses on the current status of in utero catheter interventions for congenital heart disease. The discussion of fetal interventions for cardiac defects briefly reviews the evolution of approaches to congenital heart disease and issues surrounding the prenatal detection of cardiac defects, the rationale f...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2004.08.005
更新日期:2004-12-01 00:00:00
abstract::At least 1 in 10 children in the United States is born into a chemically dependent family. Parental addiction has long-lasting detrimental effects on the health and safety of children. We must mobilize to free children from the double jeopardy of substance abuse and child abuse, and interrupt the multigenerational pat...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)36941-3
更新日期:1990-08-01 00:00:00
abstract::Children's temperament continues to make a significant contribution to their physical health, development, and behavior as they progress into later childhood and adolescence. The definition of temperament as behavioral style remains the same, although the relative importance of the several dimensions shifts, factors a...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38345-6
更新日期:1992-06-01 00:00:00
abstract::Abnormalities of occlusal development manifest themselves clinically as a need for orthodontic treatment. There are many circumstances in which there is an interaction between traditional pediatric concerns and occlusal abnormalities. In some cases medical treatment impacts on the development of occlusion. In other ca...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38192-5
更新日期:1991-10-01 00:00:00
abstract::All definitions of bronchopulmonary dysplasia (BPD) have limitations and a new definition for the purpose of clinical research, benchmarking, and prognostic prediction is needed. Different inhaled and systemic drugs are currently used to prevent or treat BPD. Despite some positive effects on BPD, more information abou...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2017.08.012
更新日期:2017-12-01 00:00:00
abstract::Evaluation and treatment of acute musculoskeletal injuries can be rewarding for primary care providers. They are common presenting complaints, and with appropriate management, many patients make a full recovery in a short period of time. This article reviews basic principles of evaluation of acutely injured children, ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2014.08.009
更新日期:2014-12-01 00:00:00
abstract::As a result of their preadoptive histories and experiences, internationally adopted children, especially those with a history of institutionalization, can present with a complex profile of developmental and behavioral issues. Although many children demonstrate significant recovery and resilience after joining their ad...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2005.06.010
更新日期:2005-10-01 00:00:00
abstract::Refugee children and international adoptees have special medical considerations that must be addressed. Providers must be aware of the immigration history, where, and under what circumstances the child lived and migrated to the United States. Federal guidelines exist regarding which infections should be screened for, ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2017.03.011
更新日期:2017-08-01 00:00:00
abstract::Caustic ingestions, both accidental and intentional, continue to cause significant morbidity and mortality. This article recommends the best methods of managing caustic ingestion and the related problems of foreign bodies in the digestive tracts of small children, and also stresses the need for prevention as the best ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)36796-7
更新日期:1989-12-01 00:00:00
abstract::Recent advances in science and technology have led to the capability of early screening of newborn infants for congenital hypothyroidism. Preliminary screening programs in North America have been established in Quebec and in the Northwestern and Northeastern United States. To date these programs have screened approxim...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/s0031-3955(16)33598-2
更新日期:1978-08-01 00:00:00
abstract::Highly specialized pediatric critical care centers have matured significantly over the past two decades; however, access to this care is limited to tertiary care facilities and constrained by geography. With the advances of transport medicine, great distances can be spanned to bring critical care to the patient and pr...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38508-x
更新日期:1993-04-01 00:00:00
abstract::Pediatric patients presenting with painless scrotal masses can be perplexing because of the long differential diagnosis. A careful plan based on the physical examination and sonogram findings localizes the mass to the testis or an extratesticular location. Sonography distinguishes solid from cystic lesions. Subsequent...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70555-1
更新日期:1997-10-01 00:00:00
abstract::The pediatric autopsy can provide great benefits to families at a time when their world is falling apart. It can be invaluable in the processing of grief that families endure, helping them to plan their future. Autopsy results not only provide information but may also provide consolation by giving the family the oppor...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38877-0
更新日期:1994-12-01 00:00:00
abstract::In spite of a large volume of data regarding the in vitro activity of single and combined antimicrobial activity, the clinical relevance of these studies is unclear. Few comparative trials of combined and single antibiotic therapy of human infection have been performed. Synergistic combination therapy has been shown t...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)34325-5
更新日期:1983-02-01 00:00:00
abstract::This article reviews the necessary skills required for clinicians to make informed decisions about the use of medications in women who are breastfeeding. Even without specific data on certain medications, this review of kinetic principles, mechanisms of medication entry into breast milk, and important infant factors c...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2012.10.009
更新日期:2013-02-01 00:00:00
abstract::In the past decade, considerable advances have occurred in our understanding of the pathophysiology of this disorder, its metabolic sequelae, and its management, particularly with respect to continuous low-dose insulin infusion and the potential benefits of phosphate. This article reviews these advances as they pertai...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)34608-9
更新日期:1984-06-01 00:00:00
abstract::Beginning with a brief description of mature anatomic pathways and neurotransmitters in the "pain system," this article details their development in the human fetus, neonate, and child. Special emphasis is given to the basic mechanisms and physiologic effects of opioid analgesia. The clinical implications of these dat...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)36722-0
更新日期:1989-08-01 00:00:00
abstract::The possibility of extending life with advanced medical procedures such as organ transplantation in childhood has made it possible to focus on patients' well-being in a wider perspective. They still experience a high prevalence of medical and physical disabilities, which definitively have an impact on a child's psycho...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(03)00128-7
更新日期:2003-12-01 00:00:00
abstract::Conjunctivitis is a common, usually mild, self-limited problem. Pathogens vary at different ages. Conjunctivitis occurs alone or as a manifestation of a systemic infection or a systemic disease. Diagnosis can usually be established by the combination of clinical and laboratory findings. Topical, systemic or combinatio...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)36367-2
更新日期:1987-12-01 00:00:00
abstract::In children, laboratory evaluations can assist in the screening of patients for inflammatory disorders, confirm diagnoses, allow for monitoring of disease activity and response to therapy, and suggest prognoses and risk of morbidities associated with rheumatic diseases. This review provides an overview of the usefulne...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2012.03.008
更新日期:2012-04-01 00:00:00
abstract::This review represents the author's personal style of practice in a new and evolving field, where the standard academic framework is still in its infancy. When there is no prior established practice to follow, good clinical care needs to come from listening very carefully to patients and empirically judging appropriat...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70107-3
更新日期:1998-12-01 00:00:00
abstract::Vascular malformations are rare but important skin disorders in children, which often require multidisciplinary care. The goal of this article is to orient pediatricians to the various types of vascular malformations. We discuss the clinical characteristics, diagnostic criteria, and management of capillary, venous, ar...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2010.08.003
更新日期:2010-10-01 00:00:00
abstract::Improvements in diagnosis and treatment have increased survival for many children with malignant bone tumors. New molecular genetic discoveries are providing insights into the mechanisms of tumorigenesis and may provide novel therapeutic modalities based on interfering with aberrant transcriptional activation by hybri...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70445-4
更新日期:1996-08-01 00:00:00
abstract::Neonatal infections continue to cause morbidity and mortality in infants. Among approximately 400,000 infants followed nationally, the incidence rates of early-onset sepsis infection within 3 days of life are 0.98 cases per 1000 live births. Newborn infants are at increased risk for infections because they have relati...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2014.11.010
更新日期:2015-04-01 00:00:00
abstract::ADDs can occur as primary genetic disorders or may develop secondary to various other conditions, including infections, trauma, malnutrition, and protein-losing states. Although antibiotics are the first-line therapy for acute infection, using them prophylactically can select for resistant organisms. IM ISG and fresh ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70275-3
更新日期:2000-12-01 00:00:00
abstract::Approximately half of children sustain some type of dental injury. Management of injuries to the anterior teeth of preschool children is directed toward minimizing potential damage to the developing permanent teeth; therefore, heroic measures to save primary teeth are not indicated. Crown fractures in the permanent de...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70258-3
更新日期:2000-10-01 00:00:00
abstract::Fluid homeostasis requires adequate water intake, regulated by an intact thirst mechanism and appropriate free water excretion by the kidneys, mediated by appropriate secretion of arginine vasopressin (AVP, also known as antidiuretic hormone). AVP exerts its antidiuretic action by binding to the X chromosome-encoded V...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/j.pcl.2011.07.013
更新日期:2011-10-01 00:00:00
abstract::The diagnosis of a parasitic infection depends upon demonstration of the organism in stool, blood, or tissue specimens, and a variety of relatively simple procedures is available for this purpose. In this article, the author describes those procedures that are most frequently used on a routine basis. ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/s0031-3955(16)34868-4
更新日期:1985-08-01 00:00:00