Isolation and characterization of the chicken vitamin D receptor gene and its promoter.

abstract：:Periodontitis, a common chronic inflammatory disease of the periodontium, is caused by dental plaque formation induced by microorganisms. Recent studies have demonstrated that lncRNAs play a critical role in the regulation of gene expression and in the pathogenesis of diseases. To demonstrate that periodontitis is ass...

journal_title：Journal of cellular biochemistry

authors： Zou Y,Li C,Shu F,Tian Z,Xu W,Xu H,Tian H,Shi R,Mao X

更新日期：2015-04-01 00:00:00

abstract：:Radioprotection is an important approach to reduce the side-effects of radiotherapy. The radioprotective effect of the flavonoids of Rosa roxburghii Tratt (FRT) has been confirmed, and the mechanism has been identified as theBcl-2/caspase-3/PARP-1 signaling pathway. In this study, we investigated the effects of FRT on...

journal_title：Journal of cellular biochemistry

authors： Xu P,Liu X,Xiong X,Zhang W,Cai X,Qiu P,Hao M,Wang L,Lu D,Zhang X,Yang W

更新日期：2017-11-01 00:00:00

abstract：:Neurological disorders, such as stroke, are triggered by a loss of neurons and glial cells. Ischemic stroke remains a substantial problem for industrialized countries. Over the previous few decades our understanding about the pathophysiology of stroke has enhanced, nevertheless, more awareness is required to advance t...

journal_title：Journal of cellular biochemistry

authors： Rikhtegar R,Yousefi M,Dolati S,Kasmaei HD,Charsouei S,Nouri M,Shakouri SK

更新日期：2019-06-01 00:00:00

abstract：:A chimeric long terminal repeat-thymidine kinase (LTR-tk) gene has been used to define the sequence requirements for glucocorticoid induction of gene expression. The original LTR-tk gene contains an entire mouse mammary tumor virus (MMTV) LTR preceding the tk gene. This gene can be expressed in a hormone-responsive fa...

journal_title：Journal of cellular biochemistry

authors： Groner B,Herrlich P,Kennedy N,Ponta H,Rahmsdorf U,Hynes NE

更新日期：1982-01-01 00:00:00

abstract：:Protein-tyrosine phosphatases (PTPases) play an important role in the regulation of insulin action by dephosphorylating the active (autophosphorylated) form of the insulin receptor and attenuating its tyrosine kinase activity. PTPases can also modulate post-receptor signalling by catalyzing the dephosphorylation of ce...

journal_title：Journal of cellular biochemistry

authors： Goldstein BJ

更新日期：1992-01-01 00:00:00

abstract：:Gastric cancer (GC) is the fourth common cancer and second leading cause of cancer-related mortality in the world. WD repeat domain 5 (WDR5) has been identified that its functions as an important role in various biological functions through the epigenetic regulation of gene transcription. However, the oncogenic effect...

journal_title：Journal of cellular biochemistry

authors： Sun W,Guo F,Liu M

更新日期：2018-04-01 00:00:00

abstract：:The active vitamin D metabolite 1,25-dihydroxyvitamin D3 [1,25-D3] is thought to promote many of its actions through interaction with a specific intracellular receptor. The discovery of such receptors in monocytes and activated lymphocytes has led investigators to evaluate the role of the hormone on the immune system....

journal_title：Journal of cellular biochemistry

authors： Lemire JM

更新日期：1992-05-01 00:00:00

abstract：:The dysregulation of miR-125a-3p has been observed in multiple tumor types. Nevertheless, the function of miR-125a-3p in papillary thyroid carcinoma (PTC) is yet to be explored. Herein, we find that miR-125a-3p is markedly downregulated in PTC tissues, and its level is inversely related to the histological grade of PT...

journal_title：Journal of cellular biochemistry

authors： Song M,Wang N,Li Z,Zhang Y,Zheng Y,Yi P,Chen J

更新日期：2020-02-01 00:00:00

abstract：:Scribble (Scrib) is a large multi-domain cytoplasmic protein that was first identified through its requirement for the establishment of epithelial polarity. We tested the hypotheses that Scrib asssociates with the basolateral membrane via multiple domains, binds specific protein partners, and is part of a multimeric c...

journal_title：Journal of cellular biochemistry

authors： Kallay LM,McNickle A,Brennwald PJ,Hubbard AL,Braiterman LT

更新日期：2006-10-01 00:00:00

abstract：:We previously suggested that keratinocyte releasable factors might modulate the wound healing process by regulating the expression of key extracellular matrix components such as collagenase (matrix metalloproteinase-1) and type I collagen in fibroblasts. The first one, we called it keratinocyte-derived anti-fibrogenic...

journal_title：Journal of cellular biochemistry

authors： Chavez-Muñoz C,Hartwell R,Jalili RB,Jafarnejad SM,Lai A,Nabai L,Ghaffari A,Hojabrpour P,Kanaan N,Duronio V,Guns E,Cherkasov A,Ghahary A

更新日期：2012-08-01 00:00:00

abstract：:Survivin is a member of the inhibitor of apoptosis (IAP) gene family, containing a single baculovirus IAP repeat (BIR) and no RING finger, that is expressed in many human cancers. Although it has been proposed to be involved in mitotic and cytokinetic processes, its functional subcellular distribution in the cytoplasm...

journal_title：Journal of cellular biochemistry

authors： Jiang X,Wilford C,Duensing S,Munger K,Jones G,Jones D

更新日期：2001-08-01 00:00:00

abstract：:Osteopontin is a secreted glycoprotein with adhesive and migratory functions. Cellular interactions with osteopontin are mediated through integrin receptors which recognize the RGD domain. Recently, CD44, a non-integrin, multifunctional adhesion molecule was identified as an osteopontin receptor. CD44 is a ubiquitous ...

journal_title：Journal of cellular biochemistry

authors： Smith LL,Greenfield BW,Aruffo A,Giachelli CM

更新日期：1999-04-01 00:00:00

abstract：:Phospholipids, sphingolipids, and cholesterol are integral components of eukaryotic cell organelles, including the nucleus. Recent evidence shows characteristic features of nuclear lipid composition and signaling, which are distinct from that of the cytoplasm and plasma membrane. While the nuclear phosphoinositol lipi...

journal_title：Journal of cellular biochemistry

authors： Fu P,Ebenezer DL,Ha AW,Suryadevara V,Harijith A,Natarajan V

更新日期：2018-08-01 00:00:00

abstract：:Evidence indicates that agonists of neuronal nicotinic receptors (nAChRs), including nicotine, can induce neuroprotective and anti-apoptotic effects in the CNS. To study these mechanisms, the present study focused on nicotine-mediated modulation of the extracellular regulated kinase 1 and 2 (ERK1/2) pathway in culture...

journal_title：Journal of cellular biochemistry

authors： Toborek M,Son KW,Pudelko A,King-Pospisil K,Wylegala E,Malecki A

更新日期：2007-02-01 00:00:00

abstract：:To study hematopoietic differentiation a variety of in vitro systems have been established using hematopoietic precursors derived from various explanted adult and fetal tissues. In this prospective we describe and discuss the potential of a novel system for studying the earliest stages of hematopoietic development. In...

journal_title：Journal of cellular biochemistry

authors： Snodgrass HR,Schmitt RM,Bruyns E

更新日期：1992-07-01 00:00:00

abstract：:Cultured human melanoma cells were found to secrete TGF-beta mostly in latent biologically inactive form but in addition five of six melanoma cell lines studied produced in conditioned culture medium active TGF-beta in the range from 370 to 610 pg per 10(6) cells per 24 h. A distinct characteristic of these melanoma c...

journal_title：Journal of cellular biochemistry

authors： Bizik J,Felnerova D,Grofova M,Vaheri A

更新日期：1996-07-01 00:00:00

abstract：:Four detergents have been compared for identification of the Plasmodium knowlesi variant antigen on infected erythrocytes by immunoprecipitation analysis. Erythrocytes infected with late trophozoite and schizont forms of cloned asexual parasites were labeled by lactoperoxidase-catalyzed radioiodination and extracted e...

journal_title：Journal of cellular biochemistry

authors： Howard RJ,Barnwell JW

更新日期：1984-01-01 00:00:00

abstract：:Resistance to therapies, recurrence, and metastasis remain challenging issues for breast cancer patients, particularly for triple-negative and breast cancer stem cells. The activation of the epithelial-to-mesenchymal transition (EMT) plays an indispensable role in the poor prognosis of those types. The accumulating pr...

journal_title：Journal of cellular biochemistry

authors： Koohestanimobarhan S,Salami S,Imeni V,Mohammadi Z,Bayat O

更新日期：2018-09-06 00:00:00

abstract：:Ischemia/reperfusion injury is a tissue injury occurring post-reperfusion of tissues with pre-existing ischemia. A good blood supply to tissues aids in the survival of ischemic tissue, however, due to prolonged ischemia the levels of ATP decrease and pH declines leading to acidosis. Reduced ATP leads to an increase in...

journal_title：Journal of cellular biochemistry

authors： Ghaderi S,Alidadiani N,SoleimaniRad J,Heidari HR,Dilaver N,Heim C,Ramsperger-Gleixner M,Baradaran B,Weyand M

更新日期：2018-09-01 00:00:00

abstract：:microRNA (miRNA) is a family of small, non-coding RNA first discovered as an important regulator of development in Caenorhabditis elegans (C. elegans). Numerous miRNAs have been found in C. elegans, and some of them are well conserved in many organisms. Though, the biologic function of miRNAs in C. elegans was largely...

journal_title：Journal of cellular biochemistry

authors： Liu J,Yang B,Ai J

更新日期：2013-05-01 00:00:00

abstract：:The infection and inflammation process is associated with disturbances in lipid and lipoprotein metabolism. The apolipoprotein E (apo E) plays an important role in the lipoprotein metabolism and has been linked to inflammatory disease such as atherosclerosis and Alzheimer disease. An anti-inflammatory effect has also ...

journal_title：Journal of cellular biochemistry

authors： Ripollés Piquer B,Nazih H,Neunlist M,Huvelin JM,Bard JM

更新日期：2004-03-01 00:00:00

abstract：:Emerging evidence indicates that some altered patterns of methylation that occur in breast tumors may also be found in breast tissue of healthy women in relation to the breast cancer (BC) risk factors. Progesterone receptor (PR) isoform α is a crucial regulator of breast hormone responsiveness and its hypermethylation...

journal_title：Journal of cellular biochemistry

authors： Daraei A,Izadi P,Khorasani G,Nafissi N,Naghizadeh MM,Younosi N,Meysamie A,Mansoori Y,Nariman-Saleh-Fam Z,Bastami M,Saadatian Z,Zendehbad Z,Tavakkoly-Bazzaz J

更新日期：2019-08-01 00:00:00

abstract：:A gene coding for the (pro)phospholipase A2 (PLA2) from bovine pancreas has been designed, synthesized, and expressed in Escherichia coli. The gene was designed with a variety of restriction sites that will facilitate future mutagenesis studies. Codons occurring frequently in prokaryotic systems were chosen whenever p...

journal_title：Journal of cellular biochemistry

authors： Noel JP,Tsai MD

更新日期：1989-07-01 00:00:00

abstract：:Regulation of mesenchymal stem cell (MSC) lineage selection is important for the generation of bone mass. Inhibition of cyclooxygenase-2 (COX2) may increase adipogenesis at the cost of decreasing osteoprogenitor output. Here we investigated the role of COX2 and its products during MSC differentiation. Indomethacin sti...

journal_title：Journal of cellular biochemistry

authors： Styner M,Sen B,Xie Z,Case N,Rubin J

更新日期：2010-11-01 00:00:00

abstract：:Bone is a target tissue of progestins, but the mechanisms by which they act are still unclear. We examined the early (5-60 s) effects of progesterone and progesterone covalently bound to BSA (P-CMO BSA), which does not enter the cell, on the cytosolic free Ca(2+) concentration ([Ca(2+)]i) and the formation of inositol...

journal_title：Journal of cellular biochemistry

authors： Grosse B,Kachkache M,Le Mellay V,Lieberherr M

更新日期：2000-08-02 00:00:00

abstract：:Scaffolds porosity has an important role in in vitro and in vivo differentiation process of stem cells with given the amount of space available to the cells to proliferate and differentiate. In the present study, chitosan with three porosities including 10%, 15%, and 20% that created by gelatin were used for investiga...

journal_title：Journal of cellular biochemistry

authors： Ardeshirylajimi A,Delgoshaie M,Mirzaei S,Khojasteh A

更新日期：2018-01-01 00:00:00

abstract：:Prostate cancer is the second highest caused by cancer-related death among males. microRNAs (miRs) have been reported to participate in carcinogenesis, yet their roles in prostate cancer are rarely studied or investigated. Therefore, the present study attempted to explore the effect of miR-137 in prostate cancer via r...

journal_title：Journal of cellular biochemistry

authors： Wu QQ,Zheng B,Weng GB,Yang HM,Ren Y,Weng XJ,Zhang SW,Zhu WZ

更新日期：2019-06-01 00:00:00

abstract：:Our previous study demonstrate that vitamin D3 induces the binding of vitamin D3 receptor (VDR) to Sp1 transcription factor and stimulates p27Kip1 expression via the Sp1 consensus sequences in the promoter. Both VDR and Sp1 are transcriptional activators, it is unclear which protein functions as the transcription comp...

journal_title：Journal of cellular biochemistry

authors： Cheng HT,Chen JY,Huang YC,Chang HC,Hung WC

更新日期：2006-08-15 00:00:00

abstract：:This study aims to explore the effect of miR-330 targeting VAV1 on amyloid β-protein (Aβ) production, oxidative stress (OS), and mitochondrial dysfunction in Alzheimer's disease (AD) mice through the MAPK signaling pathway. Putative targeted gene of miR-330 was performed by a miRNA target prediction website and dual-l...

journal_title：Journal of cellular biochemistry

authors： Zhou Y,Wang ZF,Li W,Hong H,Chen J,Tian Y,Liu ZY

更新日期：2018-07-01 00:00:00

abstract：:We investigated the early effects of the anti-idiotypic antibody (clone 1D5), which recognized the estrogen receptor (ER), on cytosolic free calcium concentration ([Ca2+]i) and its long term effects on creatine kinase (CK) specific activity in female human and rat osteoblasts. These actions were compared to the known ...

journal_title：Journal of cellular biochemistry

authors： Sömjen D,Kohen F,Lieberherr M

更新日期：1997-04-01 00:00:00